data_AF-Q8R3G1-F1
#
_entry.id AF-Q8R3G1-F1
#
loop_
_atom_type.symbol
C 
N 
O 
S 
#
loop_
_audit_author.name
_audit_author.pdbx_ordinal
"Jumper, John"               1  
"Evans, Richard"             2  
"Pritzel, Alexander"         3  
"Green, Tim"                 4  
"Figurnov, Michael"          5  
"Ronneberger, Olaf"          6  
"Tunyasuvunakool, Kathryn"   7  
"Bates, Russ"                8  
"Zidek, Augustin"            9  
"Potapenko, Anna"            10 
"Bridgland, Alex"            11 
"Meyer, Clemens"             12 
"Kohl, Simon A. A."          13 
"Ballard, Andrew J."         14 
"Cowie, Andrew"              15 
"Romera-Paredes, Bernardino" 16 
"Nikolov, Stanislav"         17 
"Jain, Rishub"               18 
"Adler, Jonas"               19 
"Back, Trevor"               20 
"Petersen, Stig"             21 
"Reiman, David"              22 
"Clancy, Ellen"              23 
"Zielinski, Michal"          24 
"Steinegger, Martin"         25 
"Pacholska, Michalina"       26 
"Berghammer, Tamas"          27 
"Silver, David"              28 
"Vinyals, Oriol"             29 
"Senior, Andrew W."          30 
"Kavukcuoglu, Koray"         31 
"Kohli, Pushmeet"            32 
"Hassabis, Demis"            33 
#
_audit_conform.dict_location https://raw.githubusercontent.com/ihmwg/ModelCIF/master/dist/mmcif_ma.dic
_audit_conform.dict_name     mmcif_ma.dic
_audit_conform.dict_version  1.3.9
#
loop_
_chem_comp.formula
_chem_comp.formula_weight
_chem_comp.id
_chem_comp.mon_nstd_flag
_chem_comp.name
_chem_comp.pdbx_synonyms
_chem_comp.type
"C3 H7 N O2"    89.093  ALA y ALANINE         ? "L-PEPTIDE LINKING" 
"C6 H15 N4 O2"  175.209 ARG y ARGININE        ? "L-PEPTIDE LINKING" 
"C4 H8 N2 O3"   132.118 ASN y ASPARAGINE      ? "L-PEPTIDE LINKING" 
"C4 H7 N O4"    133.103 ASP y "ASPARTIC ACID" ? "L-PEPTIDE LINKING" 
"C3 H7 N O2 S"  121.158 CYS y CYSTEINE        ? "L-PEPTIDE LINKING" 
"C5 H10 N2 O3"  146.144 GLN y GLUTAMINE       ? "L-PEPTIDE LINKING" 
"C5 H9 N O4"    147.129 GLU y "GLUTAMIC ACID" ? "L-PEPTIDE LINKING" 
"C2 H5 N O2"    75.067  GLY y GLYCINE         ? "PEPTIDE LINKING"   
"C6 H10 N3 O2"  156.162 HIS y HISTIDINE       ? "L-PEPTIDE LINKING" 
"C6 H13 N O2"   131.173 ILE y ISOLEUCINE      ? "L-PEPTIDE LINKING" 
"C6 H13 N O2"   131.173 LEU y LEUCINE         ? "L-PEPTIDE LINKING" 
"C6 H15 N2 O2"  147.195 LYS y LYSINE          ? "L-PEPTIDE LINKING" 
"C5 H11 N O2 S" 149.211 MET y METHIONINE      ? "L-PEPTIDE LINKING" 
"C9 H11 N O2"   165.189 PHE y PHENYLALANINE   ? "L-PEPTIDE LINKING" 
"C5 H9 N O2"    115.130 PRO y PROLINE         ? "L-PEPTIDE LINKING" 
"C3 H7 N O3"    105.093 SER y SERINE          ? "L-PEPTIDE LINKING" 
"C4 H9 N O3"    119.119 THR y THREONINE       ? "L-PEPTIDE LINKING" 
"C11 H12 N2 O2" 204.225 TRP y TRYPTOPHAN      ? "L-PEPTIDE LINKING" 
"C9 H11 N O3"   181.189 TYR y TYROSINE        ? "L-PEPTIDE LINKING" 
"C5 H11 N O2"   117.146 VAL y VALINE          ? "L-PEPTIDE LINKING" 
#
_citation.book_publisher          ?
_citation.country                 UK
_citation.id                      primary
_citation.journal_full            Nature
_citation.journal_id_ASTM         NATUAS
_citation.journal_id_CSD          0006
_citation.journal_id_ISSN         0028-0836
_citation.journal_volume          596
_citation.page_first              583
_citation.page_last               589
_citation.pdbx_database_id_DOI    10.1038/s41586-021-03819-2
_citation.pdbx_database_id_PubMed 34265844
_citation.title                   "Highly accurate protein structure prediction with AlphaFold"
_citation.year                    2021
#
loop_
_citation_author.citation_id
_citation_author.name
_citation_author.ordinal
1 "Jumper, John"               1  
1 "Evans, Richard"             2  
1 "Pritzel, Alexander"         3  
1 "Green, Tim"                 4  
1 "Figurnov, Michael"          5  
1 "Ronneberger, Olaf"          6  
1 "Tunyasuvunakool, Kathryn"   7  
1 "Bates, Russ"                8  
1 "Zidek, Augustin"            9  
1 "Potapenko, Anna"            10 
1 "Bridgland, Alex"            11 
1 "Meyer, Clemens"             12 
1 "Kohl, Simon A. A."          13 
1 "Ballard, Andrew J."         14 
1 "Cowie, Andrew"              15 
1 "Romera-Paredes, Bernardino" 16 
1 "Nikolov, Stanislav"         17 
1 "Jain, Rishub"               18 
1 "Adler, Jonas"               19 
1 "Back, Trevor"               20 
1 "Petersen, Stig"             21 
1 "Reiman, David"              22 
1 "Clancy, Ellen"              23 
1 "Zielinski, Michal"          24 
1 "Steinegger, Martin"         25 
1 "Pacholska, Michalina"       26 
1 "Berghammer, Tamas"          27 
1 "Silver, David"              28 
1 "Vinyals, Oriol"             29 
1 "Senior, Andrew W."          30 
1 "Kavukcuoglu, Koray"         31 
1 "Kohli, Pushmeet"            32 
1 "Hassabis, Demis"            33 
#
_database_2.database_code AF-Q8R3G1-F1
_database_2.database_id   AlphaFoldDB
#
_entity.details                  ?
_entity.formula_weight           ?
_entity.id                       1
_entity.pdbx_description         "Nuclear inhibitor of protein phosphatase 1"
_entity.pdbx_ec                  ?
_entity.pdbx_fragment            ?
_entity.pdbx_mutation            ?
_entity.pdbx_number_of_molecules 1
_entity.src_method               man
_entity.type                     polymer
#
_entity_poly.entity_id                    1
_entity_poly.nstd_linkage                 no
_entity_poly.nstd_monomer                 no
_entity_poly.pdbx_seq_one_letter_code     
;MAAAVNSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHL
KRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEE
TELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRMEG
SGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSETGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVAINPTPNPA
VYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI
;
_entity_poly.pdbx_seq_one_letter_code_can 
;MAAAVNSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHL
KRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEE
TELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRMEG
SGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSETGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVAINPTPNPA
VYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI
;
_entity_poly.pdbx_strand_id               A
_entity_poly.type                         polypeptide(L)
#
loop_
_entity_poly_seq.entity_id
_entity_poly_seq.hetero
_entity_poly_seq.mon_id
_entity_poly_seq.num
1 n MET 1   
1 n ALA 2   
1 n ALA 3   
1 n ALA 4   
1 n VAL 5   
1 n ASN 6   
1 n SER 7   
1 n GLY 8   
1 n SER 9   
1 n SER 10  
1 n LEU 11  
1 n PRO 12  
1 n LEU 13  
1 n PHE 14  
1 n ASP 15  
1 n CYS 16  
1 n PRO 17  
1 n THR 18  
1 n TRP 19  
1 n ALA 20  
1 n GLY 21  
1 n LYS 22  
1 n PRO 23  
1 n PRO 24  
1 n PRO 25  
1 n GLY 26  
1 n LEU 27  
1 n HIS 28  
1 n LEU 29  
1 n ASP 30  
1 n VAL 31  
1 n VAL 32  
1 n LYS 33  
1 n GLY 34  
1 n ASP 35  
1 n LYS 36  
1 n LEU 37  
1 n ILE 38  
1 n GLU 39  
1 n LYS 40  
1 n LEU 41  
1 n ILE 42  
1 n ILE 43  
1 n ASP 44  
1 n GLU 45  
1 n LYS 46  
1 n LYS 47  
1 n TYR 48  
1 n TYR 49  
1 n LEU 50  
1 n PHE 51  
1 n GLY 52  
1 n ARG 53  
1 n ASN 54  
1 n PRO 55  
1 n ASP 56  
1 n LEU 57  
1 n CYS 58  
1 n ASP 59  
1 n PHE 60  
1 n THR 61  
1 n ILE 62  
1 n ASP 63  
1 n HIS 64  
1 n GLN 65  
1 n SER 66  
1 n CYS 67  
1 n SER 68  
1 n ARG 69  
1 n VAL 70  
1 n HIS 71  
1 n ALA 72  
1 n ALA 73  
1 n LEU 74  
1 n VAL 75  
1 n TYR 76  
1 n HIS 77  
1 n LYS 78  
1 n HIS 79  
1 n LEU 80  
1 n LYS 81  
1 n ARG 82  
1 n VAL 83  
1 n PHE 84  
1 n LEU 85  
1 n ILE 86  
1 n ASP 87  
1 n LEU 88  
1 n ASN 89  
1 n SER 90  
1 n THR 91  
1 n HIS 92  
1 n GLY 93  
1 n THR 94  
1 n PHE 95  
1 n LEU 96  
1 n GLY 97  
1 n HIS 98  
1 n ILE 99  
1 n ARG 100 
1 n LEU 101 
1 n GLU 102 
1 n PRO 103 
1 n HIS 104 
1 n LYS 105 
1 n PRO 106 
1 n GLN 107 
1 n GLN 108 
1 n ILE 109 
1 n PRO 110 
1 n ILE 111 
1 n ASP 112 
1 n SER 113 
1 n THR 114 
1 n VAL 115 
1 n SER 116 
1 n PHE 117 
1 n GLY 118 
1 n ALA 119 
1 n SER 120 
1 n THR 121 
1 n ARG 122 
1 n ALA 123 
1 n TYR 124 
1 n THR 125 
1 n LEU 126 
1 n ARG 127 
1 n GLU 128 
1 n LYS 129 
1 n PRO 130 
1 n GLN 131 
1 n THR 132 
1 n LEU 133 
1 n PRO 134 
1 n SER 135 
1 n ALA 136 
1 n VAL 137 
1 n LYS 138 
1 n GLY 139 
1 n ASP 140 
1 n GLU 141 
1 n LYS 142 
1 n MET 143 
1 n GLY 144 
1 n GLY 145 
1 n GLU 146 
1 n ASP 147 
1 n ASP 148 
1 n GLU 149 
1 n LEU 150 
1 n LYS 151 
1 n GLY 152 
1 n LEU 153 
1 n LEU 154 
1 n GLY 155 
1 n LEU 156 
1 n PRO 157 
1 n GLU 158 
1 n GLU 159 
1 n GLU 160 
1 n THR 161 
1 n GLU 162 
1 n LEU 163 
1 n ASP 164 
1 n ASN 165 
1 n LEU 166 
1 n THR 167 
1 n GLU 168 
1 n PHE 169 
1 n ASN 170 
1 n THR 171 
1 n ALA 172 
1 n HIS 173 
1 n ASN 174 
1 n LYS 175 
1 n ARG 176 
1 n ILE 177 
1 n SER 178 
1 n THR 179 
1 n LEU 180 
1 n THR 181 
1 n ILE 182 
1 n GLU 183 
1 n GLU 184 
1 n GLY 185 
1 n ASN 186 
1 n LEU 187 
1 n ASP 188 
1 n ILE 189 
1 n GLN 190 
1 n ARG 191 
1 n PRO 192 
1 n LYS 193 
1 n ARG 194 
1 n LYS 195 
1 n ARG 196 
1 n LYS 197 
1 n ASN 198 
1 n SER 199 
1 n ARG 200 
1 n VAL 201 
1 n THR 202 
1 n PHE 203 
1 n SER 204 
1 n GLU 205 
1 n ASP 206 
1 n ASP 207 
1 n GLU 208 
1 n ILE 209 
1 n ILE 210 
1 n ASN 211 
1 n PRO 212 
1 n GLU 213 
1 n ASP 214 
1 n VAL 215 
1 n ASP 216 
1 n PRO 217 
1 n SER 218 
1 n VAL 219 
1 n GLY 220 
1 n ARG 221 
1 n PHE 222 
1 n ARG 223 
1 n ASN 224 
1 n MET 225 
1 n VAL 226 
1 n GLN 227 
1 n THR 228 
1 n ALA 229 
1 n VAL 230 
1 n VAL 231 
1 n PRO 232 
1 n VAL 233 
1 n LYS 234 
1 n LYS 235 
1 n LYS 236 
1 n ARG 237 
1 n MET 238 
1 n GLU 239 
1 n GLY 240 
1 n SER 241 
1 n GLY 242 
1 n SER 243 
1 n LEU 244 
1 n GLY 245 
1 n LEU 246 
1 n GLU 247 
1 n GLU 248 
1 n SER 249 
1 n GLY 250 
1 n SER 251 
1 n ARG 252 
1 n ARG 253 
1 n MET 254 
1 n GLN 255 
1 n ASN 256 
1 n PHE 257 
1 n ALA 258 
1 n PHE 259 
1 n SER 260 
1 n GLY 261 
1 n GLY 262 
1 n LEU 263 
1 n TYR 264 
1 n GLY 265 
1 n GLY 266 
1 n LEU 267 
1 n PRO 268 
1 n PRO 269 
1 n THR 270 
1 n HIS 271 
1 n SER 272 
1 n GLU 273 
1 n THR 274 
1 n GLY 275 
1 n SER 276 
1 n GLN 277 
1 n PRO 278 
1 n HIS 279 
1 n GLY 280 
1 n ILE 281 
1 n HIS 282 
1 n GLY 283 
1 n THR 284 
1 n ALA 285 
1 n LEU 286 
1 n ILE 287 
1 n GLY 288 
1 n GLY 289 
1 n LEU 290 
1 n PRO 291 
1 n MET 292 
1 n PRO 293 
1 n TYR 294 
1 n PRO 295 
1 n ASN 296 
1 n LEU 297 
1 n ALA 298 
1 n PRO 299 
1 n ASP 300 
1 n VAL 301 
1 n ASP 302 
1 n LEU 303 
1 n THR 304 
1 n PRO 305 
1 n VAL 306 
1 n VAL 307 
1 n PRO 308 
1 n SER 309 
1 n ALA 310 
1 n VAL 311 
1 n ALA 312 
1 n ILE 313 
1 n ASN 314 
1 n PRO 315 
1 n THR 316 
1 n PRO 317 
1 n ASN 318 
1 n PRO 319 
1 n ALA 320 
1 n VAL 321 
1 n TYR 322 
1 n ASN 323 
1 n PRO 324 
1 n GLU 325 
1 n ALA 326 
1 n VAL 327 
1 n ASN 328 
1 n GLU 329 
1 n PRO 330 
1 n LYS 331 
1 n LYS 332 
1 n LYS 333 
1 n LYS 334 
1 n TYR 335 
1 n ALA 336 
1 n LYS 337 
1 n GLU 338 
1 n ALA 339 
1 n TRP 340 
1 n PRO 341 
1 n GLY 342 
1 n LYS 343 
1 n LYS 344 
1 n PRO 345 
1 n THR 346 
1 n PRO 347 
1 n SER 348 
1 n LEU 349 
1 n LEU 350 
1 n ILE 351 
#
loop_
_ma_data.content_type
_ma_data.id
_ma_data.name
"model coordinates" 1 Model             
"input structure"   2 "Input structure" 
#
_ma_model_list.data_id          1
_ma_model_list.model_group_id   1
_ma_model_list.model_group_name "AlphaFold Monomer v2.0 model"
_ma_model_list.model_id         1
_ma_model_list.model_name       "Top ranked model"
_ma_model_list.model_type       "Ab initio model"
_ma_model_list.ordinal_id       1
#
loop_
_ma_protocol_step.method_type
_ma_protocol_step.ordinal_id
_ma_protocol_step.protocol_id
_ma_protocol_step.step_id
"coevolution MSA" 1 1 1 
"template search" 2 1 2 
modeling          3 1 3 
#
loop_
_ma_qa_metric.id
_ma_qa_metric.mode
_ma_qa_metric.name
_ma_qa_metric.software_group_id
_ma_qa_metric.type
1 global pLDDT 1 pLDDT 
2 local  pLDDT 1 pLDDT 
#
_ma_qa_metric_global.metric_id    1
_ma_qa_metric_global.metric_value 68.99
_ma_qa_metric_global.model_id     1
_ma_qa_metric_global.ordinal_id   1
#
loop_
_ma_qa_metric_local.label_asym_id
_ma_qa_metric_local.label_comp_id
_ma_qa_metric_local.label_seq_id
_ma_qa_metric_local.metric_id
_ma_qa_metric_local.metric_value
_ma_qa_metric_local.model_id
_ma_qa_metric_local.ordinal_id
A MET 1   2 37.21 1 1   
A ALA 2   2 43.64 1 2   
A ALA 3   2 53.16 1 3   
A ALA 4   2 46.14 1 4   
A VAL 5   2 56.84 1 5   
A ASN 6   2 37.39 1 6   
A SER 7   2 47.96 1 7   
A GLY 8   2 36.94 1 8   
A SER 9   2 45.69 1 9   
A SER 10  2 57.84 1 10  
A LEU 11  2 58.15 1 11  
A PRO 12  2 64.29 1 12  
A LEU 13  2 74.95 1 13  
A PHE 14  2 85.59 1 14  
A ASP 15  2 86.37 1 15  
A CYS 16  2 87.01 1 16  
A PRO 17  2 90.70 1 17  
A THR 18  2 91.70 1 18  
A TRP 19  2 93.14 1 19  
A ALA 20  2 93.60 1 20  
A GLY 21  2 91.46 1 21  
A LYS 22  2 90.55 1 22  
A PRO 23  2 91.05 1 23  
A PRO 24  2 88.20 1 24  
A PRO 25  2 87.27 1 25  
A GLY 26  2 87.61 1 26  
A LEU 27  2 91.62 1 27  
A HIS 28  2 92.85 1 28  
A LEU 29  2 94.26 1 29  
A ASP 30  2 94.62 1 30  
A VAL 31  2 95.22 1 31  
A VAL 32  2 95.22 1 32  
A LYS 33  2 94.00 1 33  
A GLY 34  2 90.92 1 34  
A ASP 35  2 89.50 1 35  
A LYS 36  2 92.86 1 36  
A LEU 37  2 91.35 1 37  
A ILE 38  2 91.81 1 38  
A GLU 39  2 92.04 1 39  
A LYS 40  2 92.45 1 40  
A LEU 41  2 92.72 1 41  
A ILE 42  2 92.41 1 42  
A ILE 43  2 92.54 1 43  
A ASP 44  2 88.88 1 44  
A GLU 45  2 86.72 1 45  
A LYS 46  2 89.98 1 46  
A LYS 47  2 91.50 1 47  
A TYR 48  2 94.04 1 48  
A TYR 49  2 95.05 1 49  
A LEU 50  2 95.13 1 50  
A PHE 51  2 95.94 1 51  
A GLY 52  2 95.11 1 52  
A ARG 53  2 94.39 1 53  
A ASN 54  2 91.93 1 54  
A PRO 55  2 91.63 1 55  
A ASP 56  2 90.08 1 56  
A LEU 57  2 88.38 1 57  
A CYS 58  2 92.19 1 58  
A ASP 59  2 92.28 1 59  
A PHE 60  2 93.92 1 60  
A THR 61  2 93.85 1 61  
A ILE 62  2 94.20 1 62  
A ASP 63  2 91.13 1 63  
A HIS 64  2 94.29 1 64  
A GLN 65  2 94.92 1 65  
A SER 66  2 95.06 1 66  
A CYS 67  2 94.97 1 67  
A SER 68  2 94.37 1 68  
A ARG 69  2 93.35 1 69  
A VAL 70  2 94.33 1 70  
A HIS 71  2 94.97 1 71  
A ALA 72  2 96.30 1 72  
A ALA 73  2 95.89 1 73  
A LEU 74  2 95.57 1 74  
A VAL 75  2 95.46 1 75  
A TYR 76  2 95.28 1 76  
A HIS 77  2 94.74 1 77  
A LYS 78  2 91.75 1 78  
A HIS 79  2 91.06 1 79  
A LEU 80  2 91.76 1 80  
A LYS 81  2 90.83 1 81  
A ARG 82  2 93.00 1 82  
A VAL 83  2 94.68 1 83  
A PHE 84  2 95.81 1 84  
A LEU 85  2 96.04 1 85  
A ILE 86  2 96.05 1 86  
A ASP 87  2 96.34 1 87  
A LEU 88  2 94.52 1 88  
A ASN 89  2 93.89 1 89  
A SER 90  2 94.27 1 90  
A THR 91  2 95.30 1 91  
A HIS 92  2 95.94 1 92  
A GLY 93  2 95.66 1 93  
A THR 94  2 97.13 1 94  
A PHE 95  2 96.73 1 95  
A LEU 96  2 95.85 1 96  
A GLY 97  2 92.82 1 97  
A HIS 98  2 91.72 1 98  
A ILE 99  2 95.42 1 99  
A ARG 100 2 96.08 1 100 
A LEU 101 2 96.15 1 101 
A GLU 102 2 96.50 1 102 
A PRO 103 2 94.80 1 103 
A HIS 104 2 91.75 1 104 
A LYS 105 2 93.95 1 105 
A PRO 106 2 94.51 1 106 
A GLN 107 2 95.98 1 107 
A GLN 108 2 94.97 1 108 
A ILE 109 2 95.12 1 109 
A PRO 110 2 93.75 1 110 
A ILE 111 2 92.71 1 111 
A ASP 112 2 93.31 1 112 
A SER 113 2 95.20 1 113 
A THR 114 2 95.56 1 114 
A VAL 115 2 96.61 1 115 
A SER 116 2 95.89 1 116 
A PHE 117 2 96.37 1 117 
A GLY 118 2 94.86 1 118 
A ALA 119 2 94.43 1 119 
A SER 120 2 93.81 1 120 
A THR 121 2 93.17 1 121 
A ARG 122 2 94.34 1 122 
A ALA 123 2 95.08 1 123 
A TYR 124 2 96.57 1 124 
A THR 125 2 95.67 1 125 
A LEU 126 2 94.75 1 126 
A ARG 127 2 92.02 1 127 
A GLU 128 2 89.25 1 128 
A LYS 129 2 80.82 1 129 
A PRO 130 2 67.36 1 130 
A GLN 131 2 61.14 1 131 
A THR 132 2 52.44 1 132 
A LEU 133 2 51.81 1 133 
A PRO 134 2 44.95 1 134 
A SER 135 2 43.99 1 135 
A ALA 136 2 43.46 1 136 
A VAL 137 2 49.86 1 137 
A LYS 138 2 49.71 1 138 
A GLY 139 2 44.35 1 139 
A ASP 140 2 50.40 1 140 
A GLU 141 2 44.52 1 141 
A LYS 142 2 50.81 1 142 
A MET 143 2 42.42 1 143 
A GLY 144 2 46.58 1 144 
A GLY 145 2 50.35 1 145 
A GLU 146 2 59.06 1 146 
A ASP 147 2 61.83 1 147 
A ASP 148 2 59.51 1 148 
A GLU 149 2 56.76 1 149 
A LEU 150 2 58.63 1 150 
A LYS 151 2 58.85 1 151 
A GLY 152 2 59.30 1 152 
A LEU 153 2 58.61 1 153 
A LEU 154 2 59.19 1 154 
A GLY 155 2 61.51 1 155 
A LEU 156 2 64.95 1 156 
A PRO 157 2 64.07 1 157 
A GLU 158 2 66.85 1 158 
A GLU 159 2 75.37 1 159 
A GLU 160 2 79.83 1 160 
A THR 161 2 81.41 1 161 
A GLU 162 2 80.68 1 162 
A LEU 163 2 80.25 1 163 
A ASP 164 2 84.26 1 164 
A ASN 165 2 84.08 1 165 
A LEU 166 2 82.92 1 166 
A THR 167 2 85.17 1 167 
A GLU 168 2 85.46 1 168 
A PHE 169 2 82.91 1 169 
A ASN 170 2 85.50 1 170 
A THR 171 2 87.03 1 171 
A ALA 172 2 81.28 1 172 
A HIS 173 2 80.76 1 173 
A ASN 174 2 77.38 1 174 
A LYS 175 2 79.72 1 175 
A ARG 176 2 67.44 1 176 
A ILE 177 2 58.75 1 177 
A SER 178 2 55.00 1 178 
A THR 179 2 52.88 1 179 
A LEU 180 2 50.30 1 180 
A THR 181 2 40.88 1 181 
A ILE 182 2 46.44 1 182 
A GLU 183 2 46.09 1 183 
A GLU 184 2 47.71 1 184 
A GLY 185 2 44.16 1 185 
A ASN 186 2 43.26 1 186 
A LEU 187 2 53.02 1 187 
A ASP 188 2 50.93 1 188 
A ILE 189 2 53.68 1 189 
A GLN 190 2 48.42 1 190 
A ARG 191 2 52.81 1 191 
A PRO 192 2 54.21 1 192 
A LYS 193 2 51.37 1 193 
A ARG 194 2 56.96 1 194 
A LYS 195 2 57.07 1 195 
A ARG 196 2 59.93 1 196 
A LYS 197 2 59.75 1 197 
A ASN 198 2 60.53 1 198 
A SER 199 2 64.72 1 199 
A ARG 200 2 68.13 1 200 
A VAL 201 2 71.62 1 201 
A THR 202 2 72.97 1 202 
A PHE 203 2 68.33 1 203 
A SER 204 2 72.96 1 204 
A GLU 205 2 70.92 1 205 
A ASP 206 2 68.75 1 206 
A ASP 207 2 67.28 1 207 
A GLU 208 2 69.67 1 208 
A ILE 209 2 69.46 1 209 
A ILE 210 2 66.79 1 210 
A ASN 211 2 70.33 1 211 
A PRO 212 2 67.62 1 212 
A GLU 213 2 67.81 1 213 
A ASP 214 2 67.66 1 214 
A VAL 215 2 66.16 1 215 
A ASP 216 2 65.51 1 216 
A PRO 217 2 68.37 1 217 
A SER 218 2 67.37 1 218 
A VAL 219 2 64.58 1 219 
A GLY 220 2 67.05 1 220 
A ARG 221 2 67.48 1 221 
A PHE 222 2 61.92 1 222 
A ARG 223 2 58.68 1 223 
A ASN 224 2 61.46 1 224 
A MET 225 2 64.94 1 225 
A VAL 226 2 63.72 1 226 
A GLN 227 2 67.78 1 227 
A THR 228 2 70.50 1 228 
A ALA 229 2 74.39 1 229 
A VAL 230 2 75.92 1 230 
A VAL 231 2 69.00 1 231 
A PRO 232 2 73.70 1 232 
A VAL 233 2 69.71 1 233 
A LYS 234 2 62.48 1 234 
A LYS 235 2 58.87 1 235 
A LYS 236 2 50.26 1 236 
A ARG 237 2 46.26 1 237 
A MET 238 2 46.37 1 238 
A GLU 239 2 44.13 1 239 
A GLY 240 2 39.35 1 240 
A SER 241 2 39.11 1 241 
A GLY 242 2 37.48 1 242 
A SER 243 2 39.32 1 243 
A LEU 244 2 45.53 1 244 
A GLY 245 2 36.94 1 245 
A LEU 246 2 44.89 1 246 
A GLU 247 2 42.94 1 247 
A GLU 248 2 42.35 1 248 
A SER 249 2 47.91 1 249 
A GLY 250 2 42.28 1 250 
A SER 251 2 44.36 1 251 
A ARG 252 2 47.35 1 252 
A ARG 253 2 42.07 1 253 
A MET 254 2 47.52 1 254 
A GLN 255 2 47.01 1 255 
A ASN 256 2 42.65 1 256 
A PHE 257 2 42.67 1 257 
A ALA 258 2 45.09 1 258 
A PHE 259 2 43.30 1 259 
A SER 260 2 52.54 1 260 
A GLY 261 2 50.30 1 261 
A GLY 262 2 49.40 1 262 
A LEU 263 2 58.73 1 263 
A TYR 264 2 61.06 1 264 
A GLY 265 2 59.50 1 265 
A GLY 266 2 63.73 1 266 
A LEU 267 2 58.01 1 267 
A PRO 268 2 61.28 1 268 
A PRO 269 2 62.43 1 269 
A THR 270 2 54.75 1 270 
A HIS 271 2 48.67 1 271 
A SER 272 2 43.79 1 272 
A GLU 273 2 42.86 1 273 
A THR 274 2 41.53 1 274 
A GLY 275 2 39.48 1 275 
A SER 276 2 41.79 1 276 
A GLN 277 2 42.39 1 277 
A PRO 278 2 41.07 1 278 
A HIS 279 2 40.42 1 279 
A GLY 280 2 38.89 1 280 
A ILE 281 2 43.42 1 281 
A HIS 282 2 38.73 1 282 
A GLY 283 2 36.94 1 283 
A THR 284 2 39.64 1 284 
A ALA 285 2 40.48 1 285 
A LEU 286 2 49.74 1 286 
A ILE 287 2 47.60 1 287 
A GLY 288 2 40.79 1 288 
A GLY 289 2 43.45 1 289 
A LEU 290 2 47.89 1 290 
A PRO 291 2 53.74 1 291 
A MET 292 2 65.48 1 292 
A PRO 293 2 62.13 1 293 
A TYR 294 2 65.58 1 294 
A PRO 295 2 62.34 1 295 
A ASN 296 2 59.26 1 296 
A LEU 297 2 50.19 1 297 
A ALA 298 2 55.74 1 298 
A PRO 299 2 61.12 1 299 
A ASP 300 2 53.53 1 300 
A VAL 301 2 64.31 1 301 
A ASP 302 2 48.09 1 302 
A LEU 303 2 48.59 1 303 
A THR 304 2 50.14 1 304 
A PRO 305 2 51.46 1 305 
A VAL 306 2 52.65 1 306 
A VAL 307 2 49.66 1 307 
A PRO 308 2 43.38 1 308 
A SER 309 2 43.01 1 309 
A ALA 310 2 41.88 1 310 
A VAL 311 2 47.33 1 311 
A ALA 312 2 43.50 1 312 
A ILE 313 2 51.12 1 313 
A ASN 314 2 51.20 1 314 
A PRO 315 2 53.40 1 315 
A THR 316 2 55.46 1 316 
A PRO 317 2 50.48 1 317 
A ASN 318 2 49.35 1 318 
A PRO 319 2 42.12 1 319 
A ALA 320 2 44.76 1 320 
A VAL 321 2 46.29 1 321 
A TYR 322 2 38.27 1 322 
A ASN 323 2 47.44 1 323 
A PRO 324 2 41.46 1 324 
A GLU 325 2 41.15 1 325 
A ALA 326 2 41.87 1 326 
A VAL 327 2 43.29 1 327 
A ASN 328 2 42.37 1 328 
A GLU 329 2 47.08 1 329 
A PRO 330 2 56.11 1 330 
A LYS 331 2 52.45 1 331 
A LYS 332 2 50.10 1 332 
A LYS 333 2 59.56 1 333 
A LYS 334 2 60.55 1 334 
A TYR 335 2 50.85 1 335 
A ALA 336 2 60.25 1 336 
A LYS 337 2 55.43 1 337 
A GLU 338 2 56.83 1 338 
A ALA 339 2 55.21 1 339 
A TRP 340 2 47.63 1 340 
A PRO 341 2 59.57 1 341 
A GLY 342 2 49.33 1 342 
A LYS 343 2 53.01 1 343 
A LYS 344 2 61.28 1 344 
A PRO 345 2 55.41 1 345 
A THR 346 2 62.00 1 346 
A PRO 347 2 61.19 1 347 
A SER 348 2 61.89 1 348 
A LEU 349 2 60.44 1 349 
A LEU 350 2 50.27 1 350 
A ILE 351 2 52.42 1 351 
#
_ma_software_group.group_id    1
_ma_software_group.ordinal_id  1
_ma_software_group.software_id 1
#
_ma_target_entity.data_id   1
_ma_target_entity.entity_id 1
_ma_target_entity.origin    "reference database"
#
_ma_target_entity_instance.asym_id   A
_ma_target_entity_instance.details   .
_ma_target_entity_instance.entity_id 1
#
_ma_target_ref_db_details.db_accession                 Q8R3G1
_ma_target_ref_db_details.db_code                      PP1R8_MOUSE
_ma_target_ref_db_details.db_name                      UNP
_ma_target_ref_db_details.gene_name                    Ppp1r8
_ma_target_ref_db_details.ncbi_taxonomy_id             10090
_ma_target_ref_db_details.organism_scientific          "Mus musculus"
_ma_target_ref_db_details.seq_db_align_begin           1
_ma_target_ref_db_details.seq_db_align_end             351
_ma_target_ref_db_details.seq_db_isoform               ?
_ma_target_ref_db_details.seq_db_sequence_checksum     D3A3BC4B2DF467A2
_ma_target_ref_db_details.seq_db_sequence_version_date 2002-06-01
_ma_target_ref_db_details.target_entity_id             1
#
loop_
_ma_template_details.ordinal_id
_ma_template_details.target_asym_id
_ma_template_details.template_auth_asym_id
_ma_template_details.template_data_id
_ma_template_details.template_entity_type
_ma_template_details.template_id
_ma_template_details.template_model_num
_ma_template_details.template_origin
_ma_template_details.template_trans_matrix_id
1 A A 2 polymer 1 1 "reference database" 1 
2 A X 2 polymer 2 1 "reference database" 1 
3 A 0 2 polymer 3 1 "reference database" 1 
4 A A 2 polymer 4 1 "reference database" 1 
#
loop_
_ma_template_ref_db_details.db_accession_code
_ma_template_ref_db_details.db_name
_ma_template_ref_db_details.template_id
2JPE PDB 1 
5Z56 PDB 2 
7ABH PDB 3 
2N84 PDB 4 
#
_ma_template_trans_matrix.id               1
_ma_template_trans_matrix.rot_matrix[1][1] 1.0
_ma_template_trans_matrix.rot_matrix[1][2] 0.0
_ma_template_trans_matrix.rot_matrix[1][3] 0.0
_ma_template_trans_matrix.rot_matrix[2][1] 0.0
_ma_template_trans_matrix.rot_matrix[2][2] 1.0
_ma_template_trans_matrix.rot_matrix[2][3] 0.0
_ma_template_trans_matrix.rot_matrix[3][1] 0.0
_ma_template_trans_matrix.rot_matrix[3][2] 0.0
_ma_template_trans_matrix.rot_matrix[3][3] 1.0
_ma_template_trans_matrix.tr_vector[1]     0.0
_ma_template_trans_matrix.tr_vector[2]     0.0
_ma_template_trans_matrix.tr_vector[3]     0.0
#
loop_
_pdbx_audit_revision_details.data_content_type
_pdbx_audit_revision_details.description
_pdbx_audit_revision_details.ordinal
_pdbx_audit_revision_details.provider
_pdbx_audit_revision_details.revision_ordinal
_pdbx_audit_revision_details.type
"Structure model" ?                                                       1 repository 1 "Initial release" 
"Structure model" "Format fixes, new metadata, initial SwissProt release" 2 repository 2 Remediation       
"Structure model" "Format fixes, new metadata, initial UniProt release"   3 repository 3 Remediation       
"Structure model" "Improved prediction accuracy, small format fixes"      4 repository 4 Remediation       
#
loop_
_pdbx_audit_revision_history.data_content_type
_pdbx_audit_revision_history.major_revision
_pdbx_audit_revision_history.minor_revision
_pdbx_audit_revision_history.ordinal
_pdbx_audit_revision_history.revision_date
"Structure model" 1 0 1 2021-07-01 
"Structure model" 2 0 2 2021-12-09 
"Structure model" 3 0 3 2022-06-01 
"Structure model" 4 0 4 2022-09-30 
#
loop_
_pdbx_data_usage.details
_pdbx_data_usage.id
_pdbx_data_usage.name
_pdbx_data_usage.type
_pdbx_data_usage.url
"Data in this file is available under a CC-BY-4.0 license." 1 CC-BY-4.0 license    https://creativecommons.org/licenses/by/4.0/ 
;ALPHAFOLD DATA, COPYRIGHT (2021) DEEPMIND TECHNOLOGIES LIMITED. THE INFORMATION
PROVIDED IS THEORETICAL MODELLING ONLY AND CAUTION SHOULD BE EXERCISED IN ITS
USE. IT IS PROVIDED "AS-IS" WITHOUT ANY WARRANTY OF ANY KIND, WHETHER EXPRESSED
OR IMPLIED. NO WARRANTY IS GIVEN THAT USE OF THE INFORMATION SHALL NOT INFRINGE
THE RIGHTS OF ANY THIRD PARTY. DISCLAIMER: THE INFORMATION IS NOT INTENDED TO BE
A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT, AND DOES
NOT CONSTITUTE MEDICAL OR OTHER PROFESSIONAL ADVICE. IT IS AVAILABLE FOR
ACADEMIC AND COMMERCIAL PURPOSES, UNDER CC-BY 4.0 LICENCE.
;
2 ?         disclaimer ?                                            
#
_pdbx_database_status.entry_id                      AF-Q8R3G1-F1
_pdbx_database_status.recvd_initial_deposition_date 2022-06-01
_pdbx_database_status.status_code                   REL
#
loop_
_pdbx_poly_seq_scheme.asym_id
_pdbx_poly_seq_scheme.auth_seq_num
_pdbx_poly_seq_scheme.entity_id
_pdbx_poly_seq_scheme.hetero
_pdbx_poly_seq_scheme.mon_id
_pdbx_poly_seq_scheme.pdb_ins_code
_pdbx_poly_seq_scheme.pdb_mon_id
_pdbx_poly_seq_scheme.pdb_seq_num
_pdbx_poly_seq_scheme.pdb_strand_id
_pdbx_poly_seq_scheme.seq_id
A 1   1 n MET . MET 1   A 1   
A 2   1 n ALA . ALA 2   A 2   
A 3   1 n ALA . ALA 3   A 3   
A 4   1 n ALA . ALA 4   A 4   
A 5   1 n VAL . VAL 5   A 5   
A 6   1 n ASN . ASN 6   A 6   
A 7   1 n SER . SER 7   A 7   
A 8   1 n GLY . GLY 8   A 8   
A 9   1 n SER . SER 9   A 9   
A 10  1 n SER . SER 10  A 10  
A 11  1 n LEU . LEU 11  A 11  
A 12  1 n PRO . PRO 12  A 12  
A 13  1 n LEU . LEU 13  A 13  
A 14  1 n PHE . PHE 14  A 14  
A 15  1 n ASP . ASP 15  A 15  
A 16  1 n CYS . CYS 16  A 16  
A 17  1 n PRO . PRO 17  A 17  
A 18  1 n THR . THR 18  A 18  
A 19  1 n TRP . TRP 19  A 19  
A 20  1 n ALA . ALA 20  A 20  
A 21  1 n GLY . GLY 21  A 21  
A 22  1 n LYS . LYS 22  A 22  
A 23  1 n PRO . PRO 23  A 23  
A 24  1 n PRO . PRO 24  A 24  
A 25  1 n PRO . PRO 25  A 25  
A 26  1 n GLY . GLY 26  A 26  
A 27  1 n LEU . LEU 27  A 27  
A 28  1 n HIS . HIS 28  A 28  
A 29  1 n LEU . LEU 29  A 29  
A 30  1 n ASP . ASP 30  A 30  
A 31  1 n VAL . VAL 31  A 31  
A 32  1 n VAL . VAL 32  A 32  
A 33  1 n LYS . LYS 33  A 33  
A 34  1 n GLY . GLY 34  A 34  
A 35  1 n ASP . ASP 35  A 35  
A 36  1 n LYS . LYS 36  A 36  
A 37  1 n LEU . LEU 37  A 37  
A 38  1 n ILE . ILE 38  A 38  
A 39  1 n GLU . GLU 39  A 39  
A 40  1 n LYS . LYS 40  A 40  
A 41  1 n LEU . LEU 41  A 41  
A 42  1 n ILE . ILE 42  A 42  
A 43  1 n ILE . ILE 43  A 43  
A 44  1 n ASP . ASP 44  A 44  
A 45  1 n GLU . GLU 45  A 45  
A 46  1 n LYS . LYS 46  A 46  
A 47  1 n LYS . LYS 47  A 47  
A 48  1 n TYR . TYR 48  A 48  
A 49  1 n TYR . TYR 49  A 49  
A 50  1 n LEU . LEU 50  A 50  
A 51  1 n PHE . PHE 51  A 51  
A 52  1 n GLY . GLY 52  A 52  
A 53  1 n ARG . ARG 53  A 53  
A 54  1 n ASN . ASN 54  A 54  
A 55  1 n PRO . PRO 55  A 55  
A 56  1 n ASP . ASP 56  A 56  
A 57  1 n LEU . LEU 57  A 57  
A 58  1 n CYS . CYS 58  A 58  
A 59  1 n ASP . ASP 59  A 59  
A 60  1 n PHE . PHE 60  A 60  
A 61  1 n THR . THR 61  A 61  
A 62  1 n ILE . ILE 62  A 62  
A 63  1 n ASP . ASP 63  A 63  
A 64  1 n HIS . HIS 64  A 64  
A 65  1 n GLN . GLN 65  A 65  
A 66  1 n SER . SER 66  A 66  
A 67  1 n CYS . CYS 67  A 67  
A 68  1 n SER . SER 68  A 68  
A 69  1 n ARG . ARG 69  A 69  
A 70  1 n VAL . VAL 70  A 70  
A 71  1 n HIS . HIS 71  A 71  
A 72  1 n ALA . ALA 72  A 72  
A 73  1 n ALA . ALA 73  A 73  
A 74  1 n LEU . LEU 74  A 74  
A 75  1 n VAL . VAL 75  A 75  
A 76  1 n TYR . TYR 76  A 76  
A 77  1 n HIS . HIS 77  A 77  
A 78  1 n LYS . LYS 78  A 78  
A 79  1 n HIS . HIS 79  A 79  
A 80  1 n LEU . LEU 80  A 80  
A 81  1 n LYS . LYS 81  A 81  
A 82  1 n ARG . ARG 82  A 82  
A 83  1 n VAL . VAL 83  A 83  
A 84  1 n PHE . PHE 84  A 84  
A 85  1 n LEU . LEU 85  A 85  
A 86  1 n ILE . ILE 86  A 86  
A 87  1 n ASP . ASP 87  A 87  
A 88  1 n LEU . LEU 88  A 88  
A 89  1 n ASN . ASN 89  A 89  
A 90  1 n SER . SER 90  A 90  
A 91  1 n THR . THR 91  A 91  
A 92  1 n HIS . HIS 92  A 92  
A 93  1 n GLY . GLY 93  A 93  
A 94  1 n THR . THR 94  A 94  
A 95  1 n PHE . PHE 95  A 95  
A 96  1 n LEU . LEU 96  A 96  
A 97  1 n GLY . GLY 97  A 97  
A 98  1 n HIS . HIS 98  A 98  
A 99  1 n ILE . ILE 99  A 99  
A 100 1 n ARG . ARG 100 A 100 
A 101 1 n LEU . LEU 101 A 101 
A 102 1 n GLU . GLU 102 A 102 
A 103 1 n PRO . PRO 103 A 103 
A 104 1 n HIS . HIS 104 A 104 
A 105 1 n LYS . LYS 105 A 105 
A 106 1 n PRO . PRO 106 A 106 
A 107 1 n GLN . GLN 107 A 107 
A 108 1 n GLN . GLN 108 A 108 
A 109 1 n ILE . ILE 109 A 109 
A 110 1 n PRO . PRO 110 A 110 
A 111 1 n ILE . ILE 111 A 111 
A 112 1 n ASP . ASP 112 A 112 
A 113 1 n SER . SER 113 A 113 
A 114 1 n THR . THR 114 A 114 
A 115 1 n VAL . VAL 115 A 115 
A 116 1 n SER . SER 116 A 116 
A 117 1 n PHE . PHE 117 A 117 
A 118 1 n GLY . GLY 118 A 118 
A 119 1 n ALA . ALA 119 A 119 
A 120 1 n SER . SER 120 A 120 
A 121 1 n THR . THR 121 A 121 
A 122 1 n ARG . ARG 122 A 122 
A 123 1 n ALA . ALA 123 A 123 
A 124 1 n TYR . TYR 124 A 124 
A 125 1 n THR . THR 125 A 125 
A 126 1 n LEU . LEU 126 A 126 
A 127 1 n ARG . ARG 127 A 127 
A 128 1 n GLU . GLU 128 A 128 
A 129 1 n LYS . LYS 129 A 129 
A 130 1 n PRO . PRO 130 A 130 
A 131 1 n GLN . GLN 131 A 131 
A 132 1 n THR . THR 132 A 132 
A 133 1 n LEU . LEU 133 A 133 
A 134 1 n PRO . PRO 134 A 134 
A 135 1 n SER . SER 135 A 135 
A 136 1 n ALA . ALA 136 A 136 
A 137 1 n VAL . VAL 137 A 137 
A 138 1 n LYS . LYS 138 A 138 
A 139 1 n GLY . GLY 139 A 139 
A 140 1 n ASP . ASP 140 A 140 
A 141 1 n GLU . GLU 141 A 141 
A 142 1 n LYS . LYS 142 A 142 
A 143 1 n MET . MET 143 A 143 
A 144 1 n GLY . GLY 144 A 144 
A 145 1 n GLY . GLY 145 A 145 
A 146 1 n GLU . GLU 146 A 146 
A 147 1 n ASP . ASP 147 A 147 
A 148 1 n ASP . ASP 148 A 148 
A 149 1 n GLU . GLU 149 A 149 
A 150 1 n LEU . LEU 150 A 150 
A 151 1 n LYS . LYS 151 A 151 
A 152 1 n GLY . GLY 152 A 152 
A 153 1 n LEU . LEU 153 A 153 
A 154 1 n LEU . LEU 154 A 154 
A 155 1 n GLY . GLY 155 A 155 
A 156 1 n LEU . LEU 156 A 156 
A 157 1 n PRO . PRO 157 A 157 
A 158 1 n GLU . GLU 158 A 158 
A 159 1 n GLU . GLU 159 A 159 
A 160 1 n GLU . GLU 160 A 160 
A 161 1 n THR . THR 161 A 161 
A 162 1 n GLU . GLU 162 A 162 
A 163 1 n LEU . LEU 163 A 163 
A 164 1 n ASP . ASP 164 A 164 
A 165 1 n ASN . ASN 165 A 165 
A 166 1 n LEU . LEU 166 A 166 
A 167 1 n THR . THR 167 A 167 
A 168 1 n GLU . GLU 168 A 168 
A 169 1 n PHE . PHE 169 A 169 
A 170 1 n ASN . ASN 170 A 170 
A 171 1 n THR . THR 171 A 171 
A 172 1 n ALA . ALA 172 A 172 
A 173 1 n HIS . HIS 173 A 173 
A 174 1 n ASN . ASN 174 A 174 
A 175 1 n LYS . LYS 175 A 175 
A 176 1 n ARG . ARG 176 A 176 
A 177 1 n ILE . ILE 177 A 177 
A 178 1 n SER . SER 178 A 178 
A 179 1 n THR . THR 179 A 179 
A 180 1 n LEU . LEU 180 A 180 
A 181 1 n THR . THR 181 A 181 
A 182 1 n ILE . ILE 182 A 182 
A 183 1 n GLU . GLU 183 A 183 
A 184 1 n GLU . GLU 184 A 184 
A 185 1 n GLY . GLY 185 A 185 
A 186 1 n ASN . ASN 186 A 186 
A 187 1 n LEU . LEU 187 A 187 
A 188 1 n ASP . ASP 188 A 188 
A 189 1 n ILE . ILE 189 A 189 
A 190 1 n GLN . GLN 190 A 190 
A 191 1 n ARG . ARG 191 A 191 
A 192 1 n PRO . PRO 192 A 192 
A 193 1 n LYS . LYS 193 A 193 
A 194 1 n ARG . ARG 194 A 194 
A 195 1 n LYS . LYS 195 A 195 
A 196 1 n ARG . ARG 196 A 196 
A 197 1 n LYS . LYS 197 A 197 
A 198 1 n ASN . ASN 198 A 198 
A 199 1 n SER . SER 199 A 199 
A 200 1 n ARG . ARG 200 A 200 
A 201 1 n VAL . VAL 201 A 201 
A 202 1 n THR . THR 202 A 202 
A 203 1 n PHE . PHE 203 A 203 
A 204 1 n SER . SER 204 A 204 
A 205 1 n GLU . GLU 205 A 205 
A 206 1 n ASP . ASP 206 A 206 
A 207 1 n ASP . ASP 207 A 207 
A 208 1 n GLU . GLU 208 A 208 
A 209 1 n ILE . ILE 209 A 209 
A 210 1 n ILE . ILE 210 A 210 
A 211 1 n ASN . ASN 211 A 211 
A 212 1 n PRO . PRO 212 A 212 
A 213 1 n GLU . GLU 213 A 213 
A 214 1 n ASP . ASP 214 A 214 
A 215 1 n VAL . VAL 215 A 215 
A 216 1 n ASP . ASP 216 A 216 
A 217 1 n PRO . PRO 217 A 217 
A 218 1 n SER . SER 218 A 218 
A 219 1 n VAL . VAL 219 A 219 
A 220 1 n GLY . GLY 220 A 220 
A 221 1 n ARG . ARG 221 A 221 
A 222 1 n PHE . PHE 222 A 222 
A 223 1 n ARG . ARG 223 A 223 
A 224 1 n ASN . ASN 224 A 224 
A 225 1 n MET . MET 225 A 225 
A 226 1 n VAL . VAL 226 A 226 
A 227 1 n GLN . GLN 227 A 227 
A 228 1 n THR . THR 228 A 228 
A 229 1 n ALA . ALA 229 A 229 
A 230 1 n VAL . VAL 230 A 230 
A 231 1 n VAL . VAL 231 A 231 
A 232 1 n PRO . PRO 232 A 232 
A 233 1 n VAL . VAL 233 A 233 
A 234 1 n LYS . LYS 234 A 234 
A 235 1 n LYS . LYS 235 A 235 
A 236 1 n LYS . LYS 236 A 236 
A 237 1 n ARG . ARG 237 A 237 
A 238 1 n MET . MET 238 A 238 
A 239 1 n GLU . GLU 239 A 239 
A 240 1 n GLY . GLY 240 A 240 
A 241 1 n SER . SER 241 A 241 
A 242 1 n GLY . GLY 242 A 242 
A 243 1 n SER . SER 243 A 243 
A 244 1 n LEU . LEU 244 A 244 
A 245 1 n GLY . GLY 245 A 245 
A 246 1 n LEU . LEU 246 A 246 
A 247 1 n GLU . GLU 247 A 247 
A 248 1 n GLU . GLU 248 A 248 
A 249 1 n SER . SER 249 A 249 
A 250 1 n GLY . GLY 250 A 250 
A 251 1 n SER . SER 251 A 251 
A 252 1 n ARG . ARG 252 A 252 
A 253 1 n ARG . ARG 253 A 253 
A 254 1 n MET . MET 254 A 254 
A 255 1 n GLN . GLN 255 A 255 
A 256 1 n ASN . ASN 256 A 256 
A 257 1 n PHE . PHE 257 A 257 
A 258 1 n ALA . ALA 258 A 258 
A 259 1 n PHE . PHE 259 A 259 
A 260 1 n SER . SER 260 A 260 
A 261 1 n GLY . GLY 261 A 261 
A 262 1 n GLY . GLY 262 A 262 
A 263 1 n LEU . LEU 263 A 263 
A 264 1 n TYR . TYR 264 A 264 
A 265 1 n GLY . GLY 265 A 265 
A 266 1 n GLY . GLY 266 A 266 
A 267 1 n LEU . LEU 267 A 267 
A 268 1 n PRO . PRO 268 A 268 
A 269 1 n PRO . PRO 269 A 269 
A 270 1 n THR . THR 270 A 270 
A 271 1 n HIS . HIS 271 A 271 
A 272 1 n SER . SER 272 A 272 
A 273 1 n GLU . GLU 273 A 273 
A 274 1 n THR . THR 274 A 274 
A 275 1 n GLY . GLY 275 A 275 
A 276 1 n SER . SER 276 A 276 
A 277 1 n GLN . GLN 277 A 277 
A 278 1 n PRO . PRO 278 A 278 
A 279 1 n HIS . HIS 279 A 279 
A 280 1 n GLY . GLY 280 A 280 
A 281 1 n ILE . ILE 281 A 281 
A 282 1 n HIS . HIS 282 A 282 
A 283 1 n GLY . GLY 283 A 283 
A 284 1 n THR . THR 284 A 284 
A 285 1 n ALA . ALA 285 A 285 
A 286 1 n LEU . LEU 286 A 286 
A 287 1 n ILE . ILE 287 A 287 
A 288 1 n GLY . GLY 288 A 288 
A 289 1 n GLY . GLY 289 A 289 
A 290 1 n LEU . LEU 290 A 290 
A 291 1 n PRO . PRO 291 A 291 
A 292 1 n MET . MET 292 A 292 
A 293 1 n PRO . PRO 293 A 293 
A 294 1 n TYR . TYR 294 A 294 
A 295 1 n PRO . PRO 295 A 295 
A 296 1 n ASN . ASN 296 A 296 
A 297 1 n LEU . LEU 297 A 297 
A 298 1 n ALA . ALA 298 A 298 
A 299 1 n PRO . PRO 299 A 299 
A 300 1 n ASP . ASP 300 A 300 
A 301 1 n VAL . VAL 301 A 301 
A 302 1 n ASP . ASP 302 A 302 
A 303 1 n LEU . LEU 303 A 303 
A 304 1 n THR . THR 304 A 304 
A 305 1 n PRO . PRO 305 A 305 
A 306 1 n VAL . VAL 306 A 306 
A 307 1 n VAL . VAL 307 A 307 
A 308 1 n PRO . PRO 308 A 308 
A 309 1 n SER . SER 309 A 309 
A 310 1 n ALA . ALA 310 A 310 
A 311 1 n VAL . VAL 311 A 311 
A 312 1 n ALA . ALA 312 A 312 
A 313 1 n ILE . ILE 313 A 313 
A 314 1 n ASN . ASN 314 A 314 
A 315 1 n PRO . PRO 315 A 315 
A 316 1 n THR . THR 316 A 316 
A 317 1 n PRO . PRO 317 A 317 
A 318 1 n ASN . ASN 318 A 318 
A 319 1 n PRO . PRO 319 A 319 
A 320 1 n ALA . ALA 320 A 320 
A 321 1 n VAL . VAL 321 A 321 
A 322 1 n TYR . TYR 322 A 322 
A 323 1 n ASN . ASN 323 A 323 
A 324 1 n PRO . PRO 324 A 324 
A 325 1 n GLU . GLU 325 A 325 
A 326 1 n ALA . ALA 326 A 326 
A 327 1 n VAL . VAL 327 A 327 
A 328 1 n ASN . ASN 328 A 328 
A 329 1 n GLU . GLU 329 A 329 
A 330 1 n PRO . PRO 330 A 330 
A 331 1 n LYS . LYS 331 A 331 
A 332 1 n LYS . LYS 332 A 332 
A 333 1 n LYS . LYS 333 A 333 
A 334 1 n LYS . LYS 334 A 334 
A 335 1 n TYR . TYR 335 A 335 
A 336 1 n ALA . ALA 336 A 336 
A 337 1 n LYS . LYS 337 A 337 
A 338 1 n GLU . GLU 338 A 338 
A 339 1 n ALA . ALA 339 A 339 
A 340 1 n TRP . TRP 340 A 340 
A 341 1 n PRO . PRO 341 A 341 
A 342 1 n GLY . GLY 342 A 342 
A 343 1 n LYS . LYS 343 A 343 
A 344 1 n LYS . LYS 344 A 344 
A 345 1 n PRO . PRO 345 A 345 
A 346 1 n THR . THR 346 A 346 
A 347 1 n PRO . PRO 347 A 347 
A 348 1 n SER . SER 348 A 348 
A 349 1 n LEU . LEU 349 A 349 
A 350 1 n LEU . LEU 350 A 350 
A 351 1 n ILE . ILE 351 A 351 
#
loop_
_software.classification
_software.date
_software.description
_software.name
_software.pdbx_ordinal
_software.type
_software.version
other ? "Structure prediction" AlphaFold 1 package v2.0 
other ? "Secondary structure"  dssp      2 library 4    
#
_struct_asym.entity_id 1
_struct_asym.id        A
#
loop_
_struct_conf.beg_auth_asym_id
_struct_conf.beg_auth_comp_id
_struct_conf.beg_auth_seq_id
_struct_conf.beg_label_asym_id
_struct_conf.beg_label_comp_id
_struct_conf.beg_label_seq_id
_struct_conf.conf_type_id
_struct_conf.end_auth_asym_id
_struct_conf.end_auth_comp_id
_struct_conf.end_auth_seq_id
_struct_conf.end_label_asym_id
_struct_conf.end_label_comp_id
_struct_conf.end_label_seq_id
_struct_conf.id
_struct_conf.pdbx_beg_PDB_ins_code
_struct_conf.pdbx_end_PDB_ins_code
A GLY 8   A GLY 8   BEND         A GLY 8   A GLY 8   BEND1          ? ? 
A LEU 13  A LEU 13  BEND         A PHE 14  A PHE 14  BEND2          ? ? 
A ASP 15  A ASP 15  HELX_LH_PP_P A PRO 17  A PRO 17  HELX_LH_PP_P1  ? ? 
A THR 18  A THR 18  TURN_TY1_P   A TRP 19  A TRP 19  TURN_TY1_P1    ? ? 
A ALA 20  A ALA 20  STRN         A ALA 20  A ALA 20  STRN1          ? ? 
A LYS 22  A LYS 22  HELX_LH_PP_P A PRO 24  A PRO 24  HELX_LH_PP_P2  ? ? 
A PRO 25  A PRO 25  TURN_TY1_P   A GLY 26  A GLY 26  TURN_TY1_P2    ? ? 
A LEU 27  A LEU 27  STRN         A LYS 33  A LYS 33  STRN2          ? ? 
A GLY 34  A GLY 34  TURN_TY1_P   A ASP 35  A ASP 35  TURN_TY1_P3    ? ? 
A LYS 36  A LYS 36  STRN         A ILE 42  A ILE 42  STRN3          ? ? 
A ASP 44  A ASP 44  BEND         A GLU 45  A GLU 45  BEND3          ? ? 
A LYS 47  A LYS 47  BEND         A LYS 47  A LYS 47  BEND4          ? ? 
A TYR 48  A TYR 48  STRN         A GLY 52  A GLY 52  STRN4          ? ? 
A ARG 53  A ARG 53  BEND         A ARG 53  A ARG 53  BEND5          ? ? 
A PRO 55  A PRO 55  TURN_TY1_P   A LEU 57  A LEU 57  TURN_TY1_P4    ? ? 
A ASP 59  A ASP 59  BEND         A ASP 59  A ASP 59  BEND6          ? ? 
A PHE 60  A PHE 60  STRN         A THR 61  A THR 61  STRN5          ? ? 
A GLN 65  A GLN 65  TURN_TY1_P   A SER 66  A SER 66  TURN_TY1_P5    ? ? 
A CYS 67  A CYS 67  BEND         A CYS 67  A CYS 67  BEND7          ? ? 
A ARG 69  A ARG 69  BEND         A VAL 70  A VAL 70  BEND8          ? ? 
A ALA 72  A ALA 72  STRN         A HIS 77  A HIS 77  STRN6          ? ? 
A LYS 78  A LYS 78  TURN_TY1_P   A LYS 81  A LYS 81  TURN_TY1_P6    ? ? 
A ARG 82  A ARG 82  STRN         A ASP 87  A ASP 87  STRN7          ? ? 
A ASN 89  A ASN 89  BEND         A ASN 89  A ASN 89  BEND9          ? ? 
A THR 91  A THR 91  BEND         A HIS 92  A HIS 92  BEND10         ? ? 
A THR 94  A THR 94  STRN         A LEU 96  A LEU 96  STRN8          ? ? 
A GLY 97  A GLY 97  TURN_TY1_P   A HIS 98  A HIS 98  TURN_TY1_P7    ? ? 
A ILE 99  A ILE 99  STRN         A ARG 100 A ARG 100 STRN9          ? ? 
A LEU 101 A LEU 101 HELX_LH_PP_P A GLU 102 A GLU 102 HELX_LH_PP_P3  ? ? 
A PRO 103 A PRO 103 STRN         A PRO 103 A PRO 103 STRN10         ? ? 
A HIS 104 A HIS 104 TURN_TY1_P   A HIS 104 A HIS 104 TURN_TY1_P8    ? ? 
A GLN 107 A GLN 107 STRN         A ILE 109 A ILE 109 STRN11         ? ? 
A PRO 110 A PRO 110 HELX_LH_PP_P A PRO 110 A PRO 110 HELX_LH_PP_P4  ? ? 
A ILE 111 A ILE 111 TURN_TY1_P   A ASP 112 A ASP 112 TURN_TY1_P9    ? ? 
A THR 114 A THR 114 STRN         A PHE 117 A PHE 117 STRN12         ? ? 
A GLY 118 A GLY 118 TURN_TY1_P   A ALA 119 A ALA 119 TURN_TY1_P10   ? ? 
A THR 121 A THR 121 BEND         A THR 121 A THR 121 BEND11         ? ? 
A ARG 122 A ARG 122 STRN         A GLU 128 A GLU 128 STRN13         ? ? 
A VAL 137 A VAL 137 BEND         A VAL 137 A VAL 137 BEND12         ? ? 
A GLU 146 A GLU 146 HELX_RH_AL_P A LEU 153 A LEU 153 HELX_RH_AL_P1  ? ? 
A LEU 154 A LEU 154 TURN_TY1_P   A GLY 155 A GLY 155 TURN_TY1_P11   ? ? 
A GLU 158 A GLU 158 BEND         A GLU 159 A GLU 159 BEND13         ? ? 
A GLU 160 A GLU 160 HELX_RH_AL_P A SER 178 A SER 178 HELX_RH_AL_P2  ? ? 
A THR 179 A THR 179 TURN_TY1_P   A THR 179 A THR 179 TURN_TY1_P12   ? ? 
A LEU 180 A LEU 180 BEND         A LEU 180 A LEU 180 BEND14         ? ? 
A GLU 184 A GLU 184 BEND         A GLU 184 A GLU 184 BEND15         ? ? 
A LEU 187 A LEU 187 TURN_TY1_P   A ASP 188 A ASP 188 TURN_TY1_P13   ? ? 
A GLU 205 A GLU 205 BEND         A GLU 205 A GLU 205 BEND16         ? ? 
A PRO 212 A PRO 212 TURN_TY1_P   A ASP 214 A ASP 214 TURN_TY1_P14   ? ? 
A VAL 215 A VAL 215 BEND         A VAL 215 A VAL 215 BEND17         ? ? 
A PRO 217 A PRO 217 TURN_TY1_P   A SER 218 A SER 218 TURN_TY1_P15   ? ? 
A VAL 219 A VAL 219 BEND         A GLY 220 A GLY 220 BEND18         ? ? 
A ARG 221 A ARG 221 TURN_TY1_P   A MET 225 A MET 225 TURN_TY1_P16   ? ? 
A MET 254 A MET 254 HELX_LH_PP_P A ASN 256 A ASN 256 HELX_LH_PP_P5  ? ? 
A LEU 263 A LEU 263 TURN_TY1_P   A GLY 266 A GLY 266 TURN_TY1_P17   ? ? 
A LEU 267 A LEU 267 HELX_LH_PP_P A PRO 269 A PRO 269 HELX_LH_PP_P6  ? ? 
A PRO 291 A PRO 291 HELX_LH_PP_P A ASN 296 A ASN 296 HELX_LH_PP_P7  ? ? 
A ALA 298 A ALA 298 HELX_LH_PP_P A ASP 300 A ASP 300 HELX_LH_PP_P8  ? ? 
A ASN 314 A ASN 314 HELX_LH_PP_P A PRO 317 A PRO 317 HELX_LH_PP_P9  ? ? 
A GLU 338 A GLU 338 HELX_LH_PP_P A PRO 341 A PRO 341 HELX_LH_PP_P10 ? ? 
A LYS 344 A LYS 344 HELX_LH_PP_P A LEU 349 A LEU 349 HELX_LH_PP_P11 ? ? 
#
loop_
_struct_conf_type.criteria
_struct_conf_type.id
DSSP BEND         
DSSP HELX_LH_PP_P 
DSSP TURN_TY1_P   
DSSP STRN         
DSSP HELX_RH_AL_P 
#
_struct_ref.db_code                  PP1R8_MOUSE
_struct_ref.db_name                  UNP
_struct_ref.entity_id                1
_struct_ref.id                       1
_struct_ref.pdbx_align_begin         1
_struct_ref.pdbx_align_end           351
_struct_ref.pdbx_db_accession        Q8R3G1
_struct_ref.pdbx_db_isoform          ?
_struct_ref.pdbx_seq_one_letter_code 
;MAAAVNSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHL
KRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEE
TELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRMEG
SGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSETGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVAINPTPNPA
VYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI
;
#
_struct_ref_seq.align_id                    1
_struct_ref_seq.db_align_beg                1
_struct_ref_seq.db_align_end                351
_struct_ref_seq.pdbx_PDB_id_code            AF-Q8R3G1-F1
_struct_ref_seq.pdbx_auth_seq_align_beg     1
_struct_ref_seq.pdbx_auth_seq_align_end     351
_struct_ref_seq.pdbx_db_accession           Q8R3G1
_struct_ref_seq.pdbx_db_align_beg_ins_code  ?
_struct_ref_seq.pdbx_db_align_end_ins_code  ?
_struct_ref_seq.pdbx_seq_align_beg_ins_code ?
_struct_ref_seq.pdbx_seq_align_end_ins_code ?
_struct_ref_seq.pdbx_strand_id              A
_struct_ref_seq.ref_id                      1
_struct_ref_seq.seq_align_beg               1
_struct_ref_seq.seq_align_end               351
#
loop_
_atom_site.group_PDB
_atom_site.id
_atom_site.type_symbol
_atom_site.label_atom_id
_atom_site.label_alt_id
_atom_site.label_comp_id
_atom_site.label_asym_id
_atom_site.label_entity_id
_atom_site.label_seq_id
_atom_site.pdbx_PDB_ins_code
_atom_site.Cartn_x
_atom_site.Cartn_y
_atom_site.Cartn_z
_atom_site.occupancy
_atom_site.B_iso_or_equiv
_atom_site.pdbx_formal_charge
_atom_site.auth_seq_id
_atom_site.auth_comp_id
_atom_site.auth_asym_id
_atom_site.auth_atom_id
_atom_site.pdbx_PDB_model_num
_atom_site.pdbx_sifts_xref_db_acc
_atom_site.pdbx_sifts_xref_db_name
_atom_site.pdbx_sifts_xref_db_num
_atom_site.pdbx_sifts_xref_db_res
ATOM 1    N N   . MET A 1 1   ? 8.069   -14.147 -24.295 1.0 37.21 ? 1   MET A N   1 Q8R3G1 UNP 1   M 
ATOM 2    C CA  . MET A 1 1   ? 8.981   -12.987 -24.159 1.0 37.21 ? 1   MET A CA  1 Q8R3G1 UNP 1   M 
ATOM 3    C C   . MET A 1 1   ? 8.710   -12.330 -22.811 1.0 37.21 ? 1   MET A C   1 Q8R3G1 UNP 1   M 
ATOM 4    C CB  . MET A 1 1   ? 8.798   -12.011 -25.340 1.0 37.21 ? 1   MET A CB  1 Q8R3G1 UNP 1   M 
ATOM 5    O O   . MET A 1 1   ? 7.825   -11.494 -22.711 1.0 37.21 ? 1   MET A O   1 Q8R3G1 UNP 1   M 
ATOM 6    C CG  . MET A 1 1   ? 9.925   -12.152 -26.366 1.0 37.21 ? 1   MET A CG  1 Q8R3G1 UNP 1   M 
ATOM 7    S SD  . MET A 1 1   ? 9.547   -11.350 -27.942 1.0 37.21 ? 1   MET A SD  1 Q8R3G1 UNP 1   M 
ATOM 8    C CE  . MET A 1 1   ? 11.148  -11.500 -28.781 1.0 37.21 ? 1   MET A CE  1 Q8R3G1 UNP 1   M 
ATOM 9    N N   . ALA A 1 2   ? 9.378   -12.806 -21.758 1.0 43.64 ? 2   ALA A N   1 Q8R3G1 UNP 2   A 
ATOM 10   C CA  . ALA A 1 2   ? 9.194   -12.360 -20.375 1.0 43.64 ? 2   ALA A CA  1 Q8R3G1 UNP 2   A 
ATOM 11   C C   . ALA A 1 2   ? 10.428  -11.563 -19.909 1.0 43.64 ? 2   ALA A C   1 Q8R3G1 UNP 2   A 
ATOM 12   C CB  . ALA A 1 2   ? 8.882   -13.573 -19.490 1.0 43.64 ? 2   ALA A CB  1 Q8R3G1 UNP 2   A 
ATOM 13   O O   . ALA A 1 2   ? 11.521  -11.757 -20.432 1.0 43.64 ? 2   ALA A O   1 Q8R3G1 UNP 2   A 
ATOM 14   N N   . ALA A 1 3   ? 10.196  -10.623 -18.994 1.0 53.16 ? 3   ALA A N   1 Q8R3G1 UNP 3   A 
ATOM 15   C CA  . ALA A 1 3   ? 11.005  -9.445  -18.679 1.0 53.16 ? 3   ALA A CA  1 Q8R3G1 UNP 3   A 
ATOM 16   C C   . ALA A 1 3   ? 12.529  -9.650  -18.550 1.0 53.16 ? 3   ALA A C   1 Q8R3G1 UNP 3   A 
ATOM 17   C CB  . ALA A 1 3   ? 10.441  -8.881  -17.367 1.0 53.16 ? 3   ALA A CB  1 Q8R3G1 UNP 3   A 
ATOM 18   O O   . ALA A 1 3   ? 13.001  -10.362 -17.670 1.0 53.16 ? 3   ALA A O   1 Q8R3G1 UNP 3   A 
ATOM 19   N N   . ALA A 1 4   ? 13.293  -8.883  -19.333 1.0 46.14 ? 4   ALA A N   1 Q8R3G1 UNP 4   A 
ATOM 20   C CA  . ALA A 1 4   ? 14.685  -8.574  -19.037 1.0 46.14 ? 4   ALA A CA  1 Q8R3G1 UNP 4   A 
ATOM 21   C C   . ALA A 1 4   ? 14.738  -7.346  -18.112 1.0 46.14 ? 4   ALA A C   1 Q8R3G1 UNP 4   A 
ATOM 22   C CB  . ALA A 1 4   ? 15.444  -8.355  -20.352 1.0 46.14 ? 4   ALA A CB  1 Q8R3G1 UNP 4   A 
ATOM 23   O O   . ALA A 1 4   ? 14.456  -6.224  -18.528 1.0 46.14 ? 4   ALA A O   1 Q8R3G1 UNP 4   A 
ATOM 24   N N   . VAL A 1 5   ? 15.087  -7.560  -16.845 1.0 56.84 ? 5   VAL A N   1 Q8R3G1 UNP 5   V 
ATOM 25   C CA  . VAL A 1 5   ? 15.636  -6.518  -15.970 1.0 56.84 ? 5   VAL A CA  1 Q8R3G1 UNP 5   V 
ATOM 26   C C   . VAL A 1 5   ? 17.047  -6.936  -15.596 1.0 56.84 ? 5   VAL A C   1 Q8R3G1 UNP 5   V 
ATOM 27   C CB  . VAL A 1 5   ? 14.765  -6.212  -14.733 1.0 56.84 ? 5   VAL A CB  1 Q8R3G1 UNP 5   V 
ATOM 28   O O   . VAL A 1 5   ? 17.261  -7.655  -14.630 1.0 56.84 ? 5   VAL A O   1 Q8R3G1 UNP 5   V 
ATOM 29   C CG1 . VAL A 1 5   ? 13.620  -5.279  -15.134 1.0 56.84 ? 5   VAL A CG1 1 Q8R3G1 UNP 5   V 
ATOM 30   C CG2 . VAL A 1 5   ? 14.158  -7.440  -14.040 1.0 56.84 ? 5   VAL A CG2 1 Q8R3G1 UNP 5   V 
ATOM 31   N N   . ASN A 1 6   ? 18.012  -6.517  -16.411 1.0 37.39 ? 6   ASN A N   1 Q8R3G1 UNP 6   N 
ATOM 32   C CA  . ASN A 1 6   ? 19.420  -6.555  -16.051 1.0 37.39 ? 6   ASN A CA  1 Q8R3G1 UNP 6   N 
ATOM 33   C C   . ASN A 1 6   ? 19.948  -5.121  -16.062 1.0 37.39 ? 6   ASN A C   1 Q8R3G1 UNP 6   N 
ATOM 34   C CB  . ASN A 1 6   ? 20.204  -7.484  -16.993 1.0 37.39 ? 6   ASN A CB  1 Q8R3G1 UNP 6   N 
ATOM 35   O O   . ASN A 1 6   ? 20.251  -4.582  -17.123 1.0 37.39 ? 6   ASN A O   1 Q8R3G1 UNP 6   N 
ATOM 36   C CG  . ASN A 1 6   ? 21.653  -7.621  -16.546 1.0 37.39 ? 6   ASN A CG  1 Q8R3G1 UNP 6   N 
ATOM 37   N ND2 . ASN A 1 6   ? 22.537  -8.034  -17.422 1.0 37.39 ? 6   ASN A ND2 1 Q8R3G1 UNP 6   N 
ATOM 38   O OD1 . ASN A 1 6   ? 22.008  -7.364  -15.408 1.0 37.39 ? 6   ASN A OD1 1 Q8R3G1 UNP 6   N 
ATOM 39   N N   . SER A 1 7   ? 20.019  -4.509  -14.884 1.0 47.96 ? 7   SER A N   1 Q8R3G1 UNP 7   S 
ATOM 40   C CA  . SER A 1 7   ? 20.835  -3.320  -14.646 1.0 47.96 ? 7   SER A CA  1 Q8R3G1 UNP 7   S 
ATOM 41   C C   . SER A 1 7   ? 21.003  -3.101  -13.141 1.0 47.96 ? 7   SER A C   1 Q8R3G1 UNP 7   S 
ATOM 42   C CB  . SER A 1 7   ? 20.261  -2.070  -15.338 1.0 47.96 ? 7   SER A CB  1 Q8R3G1 UNP 7   S 
ATOM 43   O O   . SER A 1 7   ? 20.171  -2.461  -12.509 1.0 47.96 ? 7   SER A O   1 Q8R3G1 UNP 7   S 
ATOM 44   O OG  . SER A 1 7   ? 18.902  -1.877  -15.008 1.0 47.96 ? 7   SER A OG  1 Q8R3G1 UNP 7   S 
ATOM 45   N N   . GLY A 1 8   ? 22.085  -3.676  -12.605 1.0 36.94 ? 8   GLY A N   1 Q8R3G1 UNP 8   G 
ATOM 46   C CA  . GLY A 1 8   ? 22.994  -3.033  -11.649 1.0 36.94 ? 8   GLY A CA  1 Q8R3G1 UNP 8   G 
ATOM 47   C C   . GLY A 1 8   ? 22.459  -2.621  -10.275 1.0 36.94 ? 8   GLY A C   1 Q8R3G1 UNP 8   G 
ATOM 48   O O   . GLY A 1 8   ? 21.796  -1.601  -10.141 1.0 36.94 ? 8   GLY A O   1 Q8R3G1 UNP 8   G 
ATOM 49   N N   . SER A 1 9   ? 22.945  -3.322  -9.244  1.0 45.69 ? 9   SER A N   1 Q8R3G1 UNP 9   S 
ATOM 50   C CA  . SER A 1 9   ? 22.877  -3.012  -7.804  1.0 45.69 ? 9   SER A CA  1 Q8R3G1 UNP 9   S 
ATOM 51   C C   . SER A 1 9   ? 21.497  -3.135  -7.142  1.0 45.69 ? 9   SER A C   1 Q8R3G1 UNP 9   S 
ATOM 52   C CB  . SER A 1 9   ? 23.597  -1.696  -7.471  1.0 45.69 ? 9   SER A CB  1 Q8R3G1 UNP 9   S 
ATOM 53   O O   . SER A 1 9   ? 20.509  -2.554  -7.570  1.0 45.69 ? 9   SER A O   1 Q8R3G1 UNP 9   S 
ATOM 54   O OG  . SER A 1 9   ? 22.910  -0.562  -7.951  1.0 45.69 ? 9   SER A OG  1 Q8R3G1 UNP 9   S 
ATOM 55   N N   . SER A 1 10  ? 21.445  -3.931  -6.072  1.0 57.84 ? 10  SER A N   1 Q8R3G1 UNP 10  S 
ATOM 56   C CA  . SER A 1 10  ? 20.278  -4.286  -5.255  1.0 57.84 ? 10  SER A CA  1 Q8R3G1 UNP 10  S 
ATOM 57   C C   . SER A 1 10  ? 19.746  -3.111  -4.424  1.0 57.84 ? 10  SER A C   1 Q8R3G1 UNP 10  S 
ATOM 58   C CB  . SER A 1 10  ? 20.693  -5.448  -4.343  1.0 57.84 ? 10  SER A CB  1 Q8R3G1 UNP 10  S 
ATOM 59   O O   . SER A 1 10  ? 19.659  -3.196  -3.197  1.0 57.84 ? 10  SER A O   1 Q8R3G1 UNP 10  S 
ATOM 60   O OG  . SER A 1 10  ? 21.810  -5.044  -3.569  1.0 57.84 ? 10  SER A OG  1 Q8R3G1 UNP 10  S 
ATOM 61   N N   . LEU A 1 11  ? 19.445  -1.985  -5.066  1.0 58.15 ? 11  LEU A N   1 Q8R3G1 UNP 11  L 
ATOM 62   C CA  . LEU A 1 11  ? 18.814  -0.865  -4.388  1.0 58.15 ? 11  LEU A CA  1 Q8R3G1 UNP 11  L 
ATOM 63   C C   . LEU A 1 11  ? 17.363  -1.233  -4.059  1.0 58.15 ? 11  LEU A C   1 Q8R3G1 UNP 11  L 
ATOM 64   C CB  . LEU A 1 11  ? 18.928  0.415   -5.229  1.0 58.15 ? 11  LEU A CB  1 Q8R3G1 UNP 11  L 
ATOM 65   O O   . LEU A 1 11  ? 16.672  -1.813  -4.906  1.0 58.15 ? 11  LEU A O   1 Q8R3G1 UNP 11  L 
ATOM 66   C CG  . LEU A 1 11  ? 20.374  0.923   -5.380  1.0 58.15 ? 11  LEU A CG  1 Q8R3G1 UNP 11  L 
ATOM 67   C CD1 . LEU A 1 11  ? 20.391  2.146   -6.294  1.0 58.15 ? 11  LEU A CD1 1 Q8R3G1 UNP 11  L 
ATOM 68   C CD2 . LEU A 1 11  ? 20.999  1.325   -4.038  1.0 58.15 ? 11  LEU A CD2 1 Q8R3G1 UNP 11  L 
ATOM 69   N N   . PRO A 1 12  ? 16.887  -0.928  -2.839  1.0 64.29 ? 12  PRO A N   1 Q8R3G1 UNP 12  P 
ATOM 70   C CA  . PRO A 1 12  ? 15.489  -1.120  -2.507  1.0 64.29 ? 12  PRO A CA  1 Q8R3G1 UNP 12  P 
ATOM 71   C C   . PRO A 1 12  ? 14.644  -0.310  -3.490  1.0 64.29 ? 12  PRO A C   1 Q8R3G1 UNP 12  P 
ATOM 72   C CB  . PRO A 1 12  ? 15.332  -0.661  -1.055  1.0 64.29 ? 12  PRO A CB  1 Q8R3G1 UNP 12  P 
ATOM 73   O O   . PRO A 1 12  ? 14.890  0.871   -3.724  1.0 64.29 ? 12  PRO A O   1 Q8R3G1 UNP 12  P 
ATOM 74   C CG  . PRO A 1 12  ? 16.470  0.342   -0.871  1.0 64.29 ? 12  PRO A CG  1 Q8R3G1 UNP 12  P 
ATOM 75   C CD  . PRO A 1 12  ? 17.571  -0.207  -1.775  1.0 64.29 ? 12  PRO A CD  1 Q8R3G1 UNP 12  P 
ATOM 76   N N   . LEU A 1 13  ? 13.645  -0.970  -4.068  1.0 74.95 ? 13  LEU A N   1 Q8R3G1 UNP 13  L 
ATOM 77   C CA  . LEU A 1 13  ? 12.728  -0.405  -5.058  1.0 74.95 ? 13  LEU A CA  1 Q8R3G1 UNP 13  L 
ATOM 78   C C   . LEU A 1 13  ? 12.066  0.905   -4.587  1.0 74.95 ? 13  LEU A C   1 Q8R3G1 UNP 13  L 
ATOM 79   C CB  . LEU A 1 13  ? 11.690  -1.509  -5.290  1.0 74.95 ? 13  LEU A CB  1 Q8R3G1 UNP 13  L 
ATOM 80   O O   . LEU A 1 13  ? 11.734  1.768   -5.397  1.0 74.95 ? 13  LEU A O   1 Q8R3G1 UNP 13  L 
ATOM 81   C CG  . LEU A 1 13  ? 10.532  -1.140  -6.219  1.0 74.95 ? 13  LEU A CG  1 Q8R3G1 UNP 13  L 
ATOM 82   C CD1 . LEU A 1 13  ? 11.023  -0.948  -7.662  1.0 74.95 ? 13  LEU A CD1 1 Q8R3G1 UNP 13  L 
ATOM 83   C CD2 . LEU A 1 13  ? 9.502   -2.265  -6.092  1.0 74.95 ? 13  LEU A CD2 1 Q8R3G1 UNP 13  L 
ATOM 84   N N   . PHE A 1 14  ? 11.887  1.044   -3.276  1.0 85.59 ? 14  PHE A N   1 Q8R3G1 UNP 14  F 
ATOM 85   C CA  . PHE A 1 14  ? 11.422  2.253   -2.622  1.0 85.59 ? 14  PHE A CA  1 Q8R3G1 UNP 14  F 
ATOM 86   C C   . PHE A 1 14  ? 12.132  2.403   -1.276  1.0 85.59 ? 14  PHE A C   1 Q8R3G1 UNP 14  F 
ATOM 87   C CB  . PHE A 1 14  ? 9.904   2.158   -2.446  1.0 85.59 ? 14  PHE A CB  1 Q8R3G1 UNP 14  F 
ATOM 88   O O   . PHE A 1 14  ? 12.092  1.486   -0.451  1.0 85.59 ? 14  PHE A O   1 Q8R3G1 UNP 14  F 
ATOM 89   C CG  . PHE A 1 14  ? 9.317   3.335   -1.703  1.0 85.59 ? 14  PHE A CG  1 Q8R3G1 UNP 14  F 
ATOM 90   C CD1 . PHE A 1 14  ? 8.806   3.181   -0.401  1.0 85.59 ? 14  PHE A CD1 1 Q8R3G1 UNP 14  F 
ATOM 91   C CD2 . PHE A 1 14  ? 9.329   4.602   -2.307  1.0 85.59 ? 14  PHE A CD2 1 Q8R3G1 UNP 14  F 
ATOM 92   C CE1 . PHE A 1 14  ? 8.304   4.297   0.291   1.0 85.59 ? 14  PHE A CE1 1 Q8R3G1 UNP 14  F 
ATOM 93   C CE2 . PHE A 1 14  ? 8.818   5.716   -1.623  1.0 85.59 ? 14  PHE A CE2 1 Q8R3G1 UNP 14  F 
ATOM 94   C CZ  . PHE A 1 14  ? 8.318   5.562   -0.321  1.0 85.59 ? 14  PHE A CZ  1 Q8R3G1 UNP 14  F 
ATOM 95   N N   . ASP A 1 15  ? 12.761  3.555   -1.045  1.0 86.37 ? 15  ASP A N   1 Q8R3G1 UNP 15  D 
ATOM 96   C CA  . ASP A 1 15  ? 13.335  3.878   0.257   1.0 86.37 ? 15  ASP A CA  1 Q8R3G1 UNP 15  D 
ATOM 97   C C   . ASP A 1 15  ? 12.293  4.578   1.133   1.0 86.37 ? 15  ASP A C   1 Q8R3G1 UNP 15  D 
ATOM 98   C CB  . ASP A 1 15  ? 14.636  4.678   0.128   1.0 86.37 ? 15  ASP A CB  1 Q8R3G1 UNP 15  D 
ATOM 99   O O   . ASP A 1 15  ? 11.698  5.595   0.765   1.0 86.37 ? 15  ASP A O   1 Q8R3G1 UNP 15  D 
ATOM 100  C CG  . ASP A 1 15  ? 15.366  4.780   1.475   1.0 86.37 ? 15  ASP A CG  1 Q8R3G1 UNP 15  D 
ATOM 101  O OD1 . ASP A 1 15  ? 15.070  3.947   2.368   1.0 86.37 ? 15  ASP A OD1 1 Q8R3G1 UNP 15  D 
ATOM 102  O OD2 . ASP A 1 15  ? 16.207  5.694   1.604   1.0 86.37 ? 15  ASP A OD2 1 Q8R3G1 UNP 15  D 
ATOM 103  N N   . CYS A 1 16  ? 12.037  3.998   2.301   1.0 87.01 ? 16  CYS A N   1 Q8R3G1 UNP 16  C 
ATOM 104  C CA  . CYS A 1 16  ? 10.999  4.479   3.193   1.0 87.01 ? 16  CYS A CA  1 Q8R3G1 UNP 16  C 
ATOM 105  C C   . CYS A 1 16  ? 11.489  5.744   3.910   1.0 87.01 ? 16  CYS A C   1 Q8R3G1 UNP 16  C 
ATOM 106  C CB  . CYS A 1 16  ? 10.646  3.371   4.182   1.0 87.01 ? 16  CYS A CB  1 Q8R3G1 UNP 16  C 
ATOM 107  O O   . CYS A 1 16  ? 12.440  5.662   4.690   1.0 87.01 ? 16  CYS A O   1 Q8R3G1 UNP 16  C 
ATOM 108  S SG  . CYS A 1 16  ? 9.418   3.980   5.373   1.0 87.01 ? 16  CYS A SG  1 Q8R3G1 UNP 16  C 
ATOM 109  N N   . PRO A 1 17  ? 10.799  6.887   3.775   1.0 90.70 ? 17  PRO A N   1 Q8R3G1 UNP 17  P 
ATOM 110  C CA  . PRO A 1 17  ? 11.256  8.116   4.400   1.0 90.70 ? 17  PRO A CA  1 Q8R3G1 UNP 17  P 
ATOM 111  C C   . PRO A 1 17  ? 11.199  8.032   5.934   1.0 90.70 ? 17  PRO A C   1 Q8R3G1 UNP 17  P 
ATOM 112  C CB  . PRO A 1 17  ? 10.359  9.209   3.834   1.0 90.70 ? 17  PRO A CB  1 Q8R3G1 UNP 17  P 
ATOM 113  O O   . PRO A 1 17  ? 10.350  7.355   6.516   1.0 90.70 ? 17  PRO A O   1 Q8R3G1 UNP 17  P 
ATOM 114  C CG  . PRO A 1 17  ? 9.072   8.478   3.464   1.0 90.70 ? 17  PRO A CG  1 Q8R3G1 UNP 17  P 
ATOM 115  C CD  . PRO A 1 17  ? 9.558   7.096   3.044   1.0 90.70 ? 17  PRO A CD  1 Q8R3G1 UNP 17  P 
ATOM 116  N N   . THR A 1 18  ? 12.079  8.772   6.611   1.0 91.70 ? 18  THR A N   1 Q8R3G1 UNP 18  T 
ATOM 117  C CA  . THR A 1 18  ? 12.238  8.753   8.083   1.0 91.70 ? 18  THR A CA  1 Q8R3G1 UNP 18  T 
ATOM 118  C C   . THR A 1 18  ? 11.008  9.258   8.850   1.0 91.70 ? 18  THR A C   1 Q8R3G1 UNP 18  T 
ATOM 119  C CB  . THR A 1 18  ? 13.447  9.611   8.485   1.0 91.70 ? 18  THR A CB  1 Q8R3G1 UNP 18  T 
ATOM 120  O O   . THR A 1 18  ? 10.771  8.889   10.009  1.0 91.70 ? 18  THR A O   1 Q8R3G1 UNP 18  T 
ATOM 121  C CG2 . THR A 1 18  ? 14.763  9.062   7.934   1.0 91.70 ? 18  THR A CG2 1 Q8R3G1 UNP 18  T 
ATOM 122  O OG1 . THR A 1 18  ? 13.292  10.917  7.976   1.0 91.70 ? 18  THR A OG1 1 Q8R3G1 UNP 18  T 
ATOM 123  N N   . TRP A 1 19  ? 10.194  10.089  8.197   1.0 93.14 ? 19  TRP A N   1 Q8R3G1 UNP 19  W 
ATOM 124  C CA  . TRP A 1 19  ? 8.933   10.613  8.717   1.0 93.14 ? 19  TRP A CA  1 Q8R3G1 UNP 19  W 
ATOM 125  C C   . TRP A 1 19  ? 7.764   9.622   8.611   1.0 93.14 ? 19  TRP A C   1 Q8R3G1 UNP 19  W 
ATOM 126  C CB  . TRP A 1 19  ? 8.629   11.937  8.013   1.0 93.14 ? 19  TRP A CB  1 Q8R3G1 UNP 19  W 
ATOM 127  O O   . TRP A 1 19  ? 6.705   9.866   9.204   1.0 93.14 ? 19  TRP A O   1 Q8R3G1 UNP 19  W 
ATOM 128  C CG  . TRP A 1 19  ? 8.680   11.934  6.514   1.0 93.14 ? 19  TRP A CG  1 Q8R3G1 UNP 19  W 
ATOM 129  C CD1 . TRP A 1 19  ? 9.673   12.468  5.766   1.0 93.14 ? 19  TRP A CD1 1 Q8R3G1 UNP 19  W 
ATOM 130  C CD2 . TRP A 1 19  ? 7.689   11.436  5.559   1.0 93.14 ? 19  TRP A CD2 1 Q8R3G1 UNP 19  W 
ATOM 131  C CE2 . TRP A 1 19  ? 8.150   11.724  4.239   1.0 93.14 ? 19  TRP A CE2 1 Q8R3G1 UNP 19  W 
ATOM 132  C CE3 . TRP A 1 19  ? 6.440   10.789  5.672   1.0 93.14 ? 19  TRP A CE3 1 Q8R3G1 UNP 19  W 
ATOM 133  N NE1 . TRP A 1 19  ? 9.359   12.358  4.426   1.0 93.14 ? 19  TRP A NE1 1 Q8R3G1 UNP 19  W 
ATOM 134  C CH2 . TRP A 1 19  ? 6.183   10.729  3.244   1.0 93.14 ? 19  TRP A CH2 1 Q8R3G1 UNP 19  W 
ATOM 135  C CZ2 . TRP A 1 19  ? 7.422   11.374  3.094   1.0 93.14 ? 19  TRP A CZ2 1 Q8R3G1 UNP 19  W 
ATOM 136  C CZ3 . TRP A 1 19  ? 5.689   10.449  4.530   1.0 93.14 ? 19  TRP A CZ3 1 Q8R3G1 UNP 19  W 
ATOM 137  N N   . ALA A 1 20  ? 7.949   8.499   7.909   1.0 93.60 ? 20  ALA A N   1 Q8R3G1 UNP 20  A 
ATOM 138  C CA  . ALA A 1 20  ? 6.947   7.451   7.822   1.0 93.60 ? 20  ALA A CA  1 Q8R3G1 UNP 20  A 
ATOM 139  C C   . ALA A 1 20  ? 6.718   6.788   9.189   1.0 93.60 ? 20  ALA A C   1 Q8R3G1 UNP 20  A 
ATOM 140  C CB  . ALA A 1 20  ? 7.356   6.418   6.773   1.0 93.60 ? 20  ALA A CB  1 Q8R3G1 UNP 20  A 
ATOM 141  O O   . ALA A 1 20  ? 7.653   6.572   9.967   1.0 93.60 ? 20  ALA A O   1 Q8R3G1 UNP 20  A 
ATOM 142  N N   . GLY A 1 21  ? 5.474   6.429   9.486   1.0 91.46 ? 21  GLY A N   1 Q8R3G1 UNP 21  G 
ATOM 143  C CA  . GLY A 1 21  ? 5.140   5.631   10.663  1.0 91.46 ? 21  GLY A CA  1 Q8R3G1 UNP 21  G 
ATOM 144  C C   . GLY A 1 21  ? 3.818   4.902   10.503  1.0 91.46 ? 21  GLY A C   1 Q8R3G1 UNP 21  G 
ATOM 145  O O   . GLY A 1 21  ? 3.234   4.918   9.426   1.0 91.46 ? 21  GLY A O   1 Q8R3G1 UNP 21  G 
ATOM 146  N N   . LYS A 1 22  ? 3.372   4.230   11.566  1.0 90.55 ? 22  LYS A N   1 Q8R3G1 UNP 22  K 
ATOM 147  C CA  . LYS A 1 22  ? 2.144   3.433   11.521  1.0 90.55 ? 22  LYS A CA  1 Q8R3G1 UNP 22  K 
ATOM 148  C C   . LYS A 1 22  ? 0.895   4.334   11.581  1.0 90.55 ? 22  LYS A C   1 Q8R3G1 UNP 22  K 
ATOM 149  C CB  . LYS A 1 22  ? 2.116   2.370   12.624  1.0 90.55 ? 22  LYS A CB  1 Q8R3G1 UNP 22  K 
ATOM 150  O O   . LYS A 1 22  ? 0.835   5.187   12.473  1.0 90.55 ? 22  LYS A O   1 Q8R3G1 UNP 22  K 
ATOM 151  C CG  . LYS A 1 22  ? 3.173   1.282   12.381  1.0 90.55 ? 22  LYS A CG  1 Q8R3G1 UNP 22  K 
ATOM 152  C CD  . LYS A 1 22  ? 2.988   0.133   13.377  1.0 90.55 ? 22  LYS A CD  1 Q8R3G1 UNP 22  K 
ATOM 153  C CE  . LYS A 1 22  ? 3.983   -0.996  13.092  1.0 90.55 ? 22  LYS A CE  1 Q8R3G1 UNP 22  K 
ATOM 154  N NZ  . LYS A 1 22  ? 3.703   -2.179  13.944  1.0 90.55 ? 22  LYS A NZ  1 Q8R3G1 UNP 22  K 
ATOM 155  N N   . PRO A 1 23  ? -0.057  4.167   10.652  1.0 91.05 ? 23  PRO A N   1 Q8R3G1 UNP 23  P 
ATOM 156  C CA  . PRO A 1 23  ? -1.367  4.804   10.718  1.0 91.05 ? 23  PRO A CA  1 Q8R3G1 UNP 23  P 
ATOM 157  C C   . PRO A 1 23  ? -2.203  4.329   11.920  1.0 91.05 ? 23  PRO A C   1 Q8R3G1 UNP 23  P 
ATOM 158  C CB  . PRO A 1 23  ? -2.065  4.504   9.389   1.0 91.05 ? 23  PRO A CB  1 Q8R3G1 UNP 23  P 
ATOM 159  O O   . PRO A 1 23  ? -1.956  3.244   12.448  1.0 91.05 ? 23  PRO A O   1 Q8R3G1 UNP 23  P 
ATOM 160  C CG  . PRO A 1 23  ? -1.155  3.547   8.628   1.0 91.05 ? 23  PRO A CG  1 Q8R3G1 UNP 23  P 
ATOM 161  C CD  . PRO A 1 23  ? 0.097   3.370   9.447   1.0 91.05 ? 23  PRO A CD  1 Q8R3G1 UNP 23  P 
ATOM 162  N N   . PRO A 1 24  ? -3.177  5.132   12.387  1.0 88.20 ? 24  PRO A N   1 Q8R3G1 UNP 24  P 
ATOM 163  C CA  . PRO A 1 24  ? -4.207  4.661   13.307  1.0 88.20 ? 24  PRO A CA  1 Q8R3G1 UNP 24  P 
ATOM 164  C C   . PRO A 1 24  ? -5.105  3.600   12.639  1.0 88.20 ? 24  PRO A C   1 Q8R3G1 UNP 24  P 
ATOM 165  C CB  . PRO A 1 24  ? -5.003  5.909   13.707  1.0 88.20 ? 24  PRO A CB  1 Q8R3G1 UNP 24  P 
ATOM 166  O O   . PRO A 1 24  ? -5.269  3.622   11.415  1.0 88.20 ? 24  PRO A O   1 Q8R3G1 UNP 24  P 
ATOM 167  C CG  . PRO A 1 24  ? -4.861  6.815   12.485  1.0 88.20 ? 24  PRO A CG  1 Q8R3G1 UNP 24  P 
ATOM 168  C CD  . PRO A 1 24  ? -3.445  6.508   12.004  1.0 88.20 ? 24  PRO A CD  1 Q8R3G1 UNP 24  P 
ATOM 169  N N   . PRO A 1 25  ? -5.702  2.688   13.430  1.0 87.27 ? 25  PRO A N   1 Q8R3G1 UNP 25  P 
ATOM 170  C CA  . PRO A 1 25  ? -6.610  1.669   12.912  1.0 87.27 ? 25  PRO A CA  1 Q8R3G1 UNP 25  P 
ATOM 171  C C   . PRO A 1 25  ? -7.853  2.307   12.286  1.0 87.27 ? 25  PRO A C   1 Q8R3G1 UNP 25  P 
ATOM 172  C CB  . PRO A 1 25  ? -6.956  0.779   14.109  1.0 87.27 ? 25  PRO A CB  1 Q8R3G1 UNP 25  P 
ATOM 173  O O   . PRO A 1 25  ? -8.427  3.234   12.856  1.0 87.27 ? 25  PRO A O   1 Q8R3G1 UNP 25  P 
ATOM 174  C CG  . PRO A 1 25  ? -6.793  1.715   15.307  1.0 87.27 ? 25  PRO A CG  1 Q8R3G1 UNP 25  P 
ATOM 175  C CD  . PRO A 1 25  ? -5.638  2.619   14.884  1.0 87.27 ? 25  PRO A CD  1 Q8R3G1 UNP 25  P 
ATOM 176  N N   . GLY A 1 26  ? -8.285  1.781   11.137  1.0 87.61 ? 26  GLY A N   1 Q8R3G1 UNP 26  G 
ATOM 177  C CA  . GLY A 1 26  ? -9.497  2.233   10.441  1.0 87.61 ? 26  GLY A CA  1 Q8R3G1 UNP 26  G 
ATOM 178  C C   . GLY A 1 26  ? -9.268  2.990   9.131   1.0 87.61 ? 26  GLY A C   1 Q8R3G1 UNP 26  G 
ATOM 179  O O   . GLY A 1 26  ? -10.226 3.196   8.386   1.0 87.61 ? 26  GLY A O   1 Q8R3G1 UNP 26  G 
ATOM 180  N N   . LEU A 1 27  ? -8.033  3.365   8.794   1.0 91.62 ? 27  LEU A N   1 Q8R3G1 UNP 27  L 
ATOM 181  C CA  . LEU A 1 27  ? -7.738  3.957   7.486   1.0 91.62 ? 27  LEU A CA  1 Q8R3G1 UNP 27  L 
ATOM 182  C C   . LEU A 1 27  ? -7.815  2.905   6.372   1.0 91.62 ? 27  LEU A C   1 Q8R3G1 UNP 27  L 
ATOM 183  C CB  . LEU A 1 27  ? -6.373  4.661   7.514   1.0 91.62 ? 27  LEU A CB  1 Q8R3G1 UNP 27  L 
ATOM 184  O O   . LEU A 1 27  ? -7.194  1.841   6.449   1.0 91.62 ? 27  LEU A O   1 Q8R3G1 UNP 27  L 
ATOM 185  C CG  . LEU A 1 27  ? -6.389  5.990   8.290   1.0 91.62 ? 27  LEU A CG  1 Q8R3G1 UNP 27  L 
ATOM 186  C CD1 . LEU A 1 27  ? -4.954  6.465   8.500   1.0 91.62 ? 27  LEU A CD1 1 Q8R3G1 UNP 27  L 
ATOM 187  C CD2 . LEU A 1 27  ? -7.134  7.096   7.540   1.0 91.62 ? 27  LEU A CD2 1 Q8R3G1 UNP 27  L 
ATOM 188  N N   . HIS A 1 28  ? -8.560  3.223   5.317   1.0 92.85 ? 28  HIS A N   1 Q8R3G1 UNP 28  H 
ATOM 189  C CA  . HIS A 1 28  ? -8.759  2.348   4.167   1.0 92.85 ? 28  HIS A CA  1 Q8R3G1 UNP 28  H 
ATOM 190  C C   . HIS A 1 28  ? -8.904  3.149   2.864   1.0 92.85 ? 28  HIS A C   1 Q8R3G1 UNP 28  H 
ATOM 191  C CB  . HIS A 1 28  ? -9.946  1.410   4.432   1.0 92.85 ? 28  HIS A CB  1 Q8R3G1 UNP 28  H 
ATOM 192  O O   . HIS A 1 28  ? -9.196  4.344   2.868   1.0 92.85 ? 28  HIS A O   1 Q8R3G1 UNP 28  H 
ATOM 193  C CG  . HIS A 1 28  ? -11.265 2.100   4.677   1.0 92.85 ? 28  HIS A CG  1 Q8R3G1 UNP 28  H 
ATOM 194  C CD2 . HIS A 1 28  ? -12.300 2.188   3.788   1.0 92.85 ? 28  HIS A CD2 1 Q8R3G1 UNP 28  H 
ATOM 195  N ND1 . HIS A 1 28  ? -11.683 2.700   5.847   1.0 92.85 ? 28  HIS A ND1 1 Q8R3G1 UNP 28  H 
ATOM 196  C CE1 . HIS A 1 28  ? -12.940 3.135   5.659   1.0 92.85 ? 28  HIS A CE1 1 Q8R3G1 UNP 28  H 
ATOM 197  N NE2 . HIS A 1 28  ? -13.367 2.824   4.428   1.0 92.85 ? 28  HIS A NE2 1 Q8R3G1 UNP 28  H 
ATOM 198  N N   . LEU A 1 29  ? -8.651  2.495   1.733   1.0 94.26 ? 29  LEU A N   1 Q8R3G1 UNP 29  L 
ATOM 199  C CA  . LEU A 1 29  ? -8.896  3.035   0.399   1.0 94.26 ? 29  LEU A CA  1 Q8R3G1 UNP 29  L 
ATOM 200  C C   . LEU A 1 29  ? -10.071 2.301   -0.231  1.0 94.26 ? 29  LEU A C   1 Q8R3G1 UNP 29  L 
ATOM 201  C CB  . LEU A 1 29  ? -7.656  2.891   -0.492  1.0 94.26 ? 29  LEU A CB  1 Q8R3G1 UNP 29  L 
ATOM 202  O O   . LEU A 1 29  ? -10.038 1.080   -0.372  1.0 94.26 ? 29  LEU A O   1 Q8R3G1 UNP 29  L 
ATOM 203  C CG  . LEU A 1 29  ? -6.448  3.729   -0.065  1.0 94.26 ? 29  LEU A CG  1 Q8R3G1 UNP 29  L 
ATOM 204  C CD1 . LEU A 1 29  ? -5.209  3.198   -0.771  1.0 94.26 ? 29  LEU A CD1 1 Q8R3G1 UNP 29  L 
ATOM 205  C CD2 . LEU A 1 29  ? -6.596  5.192   -0.470  1.0 94.26 ? 29  LEU A CD2 1 Q8R3G1 UNP 29  L 
ATOM 206  N N   . ASP A 1 30  ? -11.060 3.057   -0.672  1.0 94.62 ? 30  ASP A N   1 Q8R3G1 UNP 30  D 
ATOM 207  C CA  . ASP A 1 30  ? -12.178 2.550   -1.451  1.0 94.62 ? 30  ASP A CA  1 Q8R3G1 UNP 30  D 
ATOM 208  C C   . ASP A 1 30  ? -11.824 2.565   -2.929  1.0 94.62 ? 30  ASP A C   1 Q8R3G1 UNP 30  D 
ATOM 209  C CB  . ASP A 1 30  ? -13.405 3.417   -1.185  1.0 94.62 ? 30  ASP A CB  1 Q8R3G1 UNP 30  D 
ATOM 210  O O   . ASP A 1 30  ? -11.521 3.615   -3.493  1.0 94.62 ? 30  ASP A O   1 Q8R3G1 UNP 30  D 
ATOM 211  C CG  . ASP A 1 30  ? -14.100 3.057   0.118   1.0 94.62 ? 30  ASP A CG  1 Q8R3G1 UNP 30  D 
ATOM 212  O OD1 . ASP A 1 30  ? -13.648 2.168   0.864   1.0 94.62 ? 30  ASP A OD1 1 Q8R3G1 UNP 30  D 
ATOM 213  O OD2 . ASP A 1 30  ? -15.171 3.640   0.355   1.0 94.62 ? 30  ASP A OD2 1 Q8R3G1 UNP 30  D 
ATOM 214  N N   . VAL A 1 31  ? -11.865 1.399   -3.564  1.0 95.22 ? 31  VAL A N   1 Q8R3G1 UNP 31  V 
ATOM 215  C CA  . VAL A 1 31  ? -11.595 1.251   -4.991  1.0 95.22 ? 31  VAL A CA  1 Q8R3G1 UNP 31  V 
ATOM 216  C C   . VAL A 1 31  ? -12.920 1.233   -5.730  1.0 95.22 ? 31  VAL A C   1 Q8R3G1 UNP 31  V 
ATOM 217  C CB  . VAL A 1 31  ? -10.776 -0.014  -5.283  1.0 95.22 ? 31  VAL A CB  1 Q8R3G1 UNP 31  V 
ATOM 218  O O   . VAL A 1 31  ? -13.641 0.242   -5.704  1.0 95.22 ? 31  VAL A O   1 Q8R3G1 UNP 31  V 
ATOM 219  C CG1 . VAL A 1 31  ? -10.324 -0.024  -6.749  1.0 95.22 ? 31  VAL A CG1 1 Q8R3G1 UNP 31  V 
ATOM 220  C CG2 . VAL A 1 31  ? -9.533  -0.097  -4.393  1.0 95.22 ? 31  VAL A CG2 1 Q8R3G1 UNP 31  V 
ATOM 221  N N   . VAL A 1 32  ? -13.238 2.319   -6.421  1.0 95.22 ? 32  VAL A N   1 Q8R3G1 UNP 32  V 
ATOM 222  C CA  . VAL A 1 32  ? -14.471 2.489   -7.193  1.0 95.22 ? 32  VAL A CA  1 Q8R3G1 UNP 32  V 
ATOM 223  C C   . VAL A 1 32  ? -14.155 2.396   -8.685  1.0 95.22 ? 32  VAL A C   1 Q8R3G1 UNP 32  V 
ATOM 224  C CB  . VAL A 1 32  ? -15.159 3.816   -6.816  1.0 95.22 ? 32  VAL A CB  1 Q8R3G1 UNP 32  V 
ATOM 225  O O   . VAL A 1 32  ? -13.135 2.902   -9.152  1.0 95.22 ? 32  VAL A O   1 Q8R3G1 UNP 32  V 
ATOM 226  C CG1 . VAL A 1 32  ? -16.482 3.995   -7.564  1.0 95.22 ? 32  VAL A CG1 1 Q8R3G1 UNP 32  V 
ATOM 227  C CG2 . VAL A 1 32  ? -15.472 3.890   -5.315  1.0 95.22 ? 32  VAL A CG2 1 Q8R3G1 UNP 32  V 
ATOM 228  N N   . LYS A 1 33  ? -15.013 1.741   -9.468  1.0 94.00 ? 33  LYS A N   1 Q8R3G1 UNP 33  K 
ATOM 229  C CA  . LYS A 1 33  ? -14.930 1.723   -10.936 1.0 94.00 ? 33  LYS A CA  1 Q8R3G1 UNP 33  K 
ATOM 230  C C   . LYS A 1 33  ? -16.300 2.068   -11.512 1.0 94.00 ? 33  LYS A C   1 Q8R3G1 UNP 33  K 
ATOM 231  C CB  . LYS A 1 33  ? -14.426 0.351   -11.405 1.0 94.00 ? 33  LYS A CB  1 Q8R3G1 UNP 33  K 
ATOM 232  O O   . LYS A 1 33  ? -17.234 1.280   -11.374 1.0 94.00 ? 33  LYS A O   1 Q8R3G1 UNP 33  K 
ATOM 233  C CG  . LYS A 1 33  ? -14.213 0.298   -12.924 1.0 94.00 ? 33  LYS A CG  1 Q8R3G1 UNP 33  K 
ATOM 234  C CD  . LYS A 1 33  ? -13.787 -1.101  -13.390 1.0 94.00 ? 33  LYS A CD  1 Q8R3G1 UNP 33  K 
ATOM 235  C CE  . LYS A 1 33  ? -13.703 -1.115  -14.923 1.0 94.00 ? 33  LYS A CE  1 Q8R3G1 UNP 33  K 
ATOM 236  N NZ  . LYS A 1 33  ? -13.375 -2.459  -15.461 1.0 94.00 ? 33  LYS A NZ  1 Q8R3G1 UNP 33  K 
ATOM 237  N N   . GLY A 1 34  ? -16.399 3.212   -12.190 1.0 90.92 ? 34  GLY A N   1 Q8R3G1 UNP 34  G 
ATOM 238  C CA  . GLY A 1 34  ? -17.702 3.782   -12.547 1.0 90.92 ? 34  GLY A CA  1 Q8R3G1 UNP 34  G 
ATOM 239  C C   . GLY A 1 34  ? -18.458 4.141   -11.269 1.0 90.92 ? 34  GLY A C   1 Q8R3G1 UNP 34  G 
ATOM 240  O O   . GLY A 1 34  ? -17.887 4.807   -10.414 1.0 90.92 ? 34  GLY A O   1 Q8R3G1 UNP 34  G 
ATOM 241  N N   . ASP A 1 35  ? -19.663 3.602   -11.105 1.0 89.50 ? 35  ASP A N   1 Q8R3G1 UNP 35  D 
ATOM 242  C CA  . ASP A 1 35  ? -20.508 3.836   -9.922  1.0 89.50 ? 35  ASP A CA  1 Q8R3G1 UNP 35  D 
ATOM 243  C C   . ASP A 1 35  ? -20.490 2.667   -8.923  1.0 89.50 ? 35  ASP A C   1 Q8R3G1 UNP 35  D 
ATOM 244  C CB  . ASP A 1 35  ? -21.931 4.173   -10.386 1.0 89.50 ? 35  ASP A CB  1 Q8R3G1 UNP 35  D 
ATOM 245  O O   . ASP A 1 35  ? -21.270 2.625   -7.976  1.0 89.50 ? 35  ASP A O   1 Q8R3G1 UNP 35  D 
ATOM 246  C CG  . ASP A 1 35  ? -21.935 5.332   -11.384 1.0 89.50 ? 35  ASP A CG  1 Q8R3G1 UNP 35  D 
ATOM 247  O OD1 . ASP A 1 35  ? -21.222 6.328   -11.132 1.0 89.50 ? 35  ASP A OD1 1 Q8R3G1 UNP 35  D 
ATOM 248  O OD2 . ASP A 1 35  ? -22.574 5.164   -12.446 1.0 89.50 ? 35  ASP A OD2 1 Q8R3G1 UNP 35  D 
ATOM 249  N N   . LYS A 1 36  ? -19.610 1.679   -9.134  1.0 92.86 ? 36  LYS A N   1 Q8R3G1 UNP 36  K 
ATOM 250  C CA  . LYS A 1 36  ? -19.545 0.466   -8.315  1.0 92.86 ? 36  LYS A CA  1 Q8R3G1 UNP 36  K 
ATOM 251  C C   . LYS A 1 36  ? -18.291 0.444   -7.449  1.0 92.86 ? 36  LYS A C   1 Q8R3G1 UNP 36  K 
ATOM 252  C CB  . LYS A 1 36  ? -19.662 -0.759  -9.232  1.0 92.86 ? 36  LYS A CB  1 Q8R3G1 UNP 36  K 
ATOM 253  O O   . LYS A 1 36  ? -17.178 0.543   -7.977  1.0 92.86 ? 36  LYS A O   1 Q8R3G1 UNP 36  K 
ATOM 254  C CG  . LYS A 1 36  ? -19.720 -2.046  -8.404  1.0 92.86 ? 36  LYS A CG  1 Q8R3G1 UNP 36  K 
ATOM 255  C CD  . LYS A 1 36  ? -19.951 -3.287  -9.265  1.0 92.86 ? 36  LYS A CD  1 Q8R3G1 UNP 36  K 
ATOM 256  C CE  . LYS A 1 36  ? -19.998 -4.488  -8.317  1.0 92.86 ? 36  LYS A CE  1 Q8R3G1 UNP 36  K 
ATOM 257  N NZ  . LYS A 1 36  ? -20.255 -5.754  -9.040  1.0 92.86 ? 36  LYS A NZ  1 Q8R3G1 UNP 36  K 
ATOM 258  N N   . LEU A 1 37  ? -18.456 0.205   -6.147  1.0 91.35 ? 37  LEU A N   1 Q8R3G1 UNP 37  L 
ATOM 259  C CA  . LEU A 1 37  ? -17.338 -0.171  -5.288  1.0 91.35 ? 37  LEU A CA  1 Q8R3G1 UNP 37  L 
ATOM 260  C C   . LEU A 1 37  ? -16.861 -1.586  -5.644  1.0 91.35 ? 37  LEU A C   1 Q8R3G1 UNP 37  L 
ATOM 261  C CB  . LEU A 1 37  ? -17.708 -0.048  -3.805  1.0 91.35 ? 37  LEU A CB  1 Q8R3G1 UNP 37  L 
ATOM 262  O O   . LEU A 1 37  ? -17.631 -2.546  -5.690  1.0 91.35 ? 37  LEU A O   1 Q8R3G1 UNP 37  L 
ATOM 263  C CG  . LEU A 1 37  ? -16.457 -0.212  -2.921  1.0 91.35 ? 37  LEU A CG  1 Q8R3G1 UNP 37  L 
ATOM 264  C CD1 . LEU A 1 37  ? -15.558 1.021   -2.903  1.0 91.35 ? 37  LEU A CD1 1 Q8R3G1 UNP 37  L 
ATOM 265  C CD2 . LEU A 1 37  ? -16.850 -0.460  -1.496  1.0 91.35 ? 37  LEU A CD2 1 Q8R3G1 UNP 37  L 
ATOM 266  N N   . ILE A 1 38  ? -15.575 -1.700  -5.952  1.0 91.81 ? 38  ILE A N   1 Q8R3G1 UNP 38  I 
ATOM 267  C CA  . ILE A 1 38  ? -14.915 -2.946  -6.334  1.0 91.81 ? 38  ILE A CA  1 Q8R3G1 UNP 38  I 
ATOM 268  C C   . ILE A 1 38  ? -14.359 -3.651  -5.103  1.0 91.81 ? 38  ILE A C   1 Q8R3G1 UNP 38  I 
ATOM 269  C CB  . ILE A 1 38  ? -13.816 -2.661  -7.383  1.0 91.81 ? 38  ILE A CB  1 Q8R3G1 UNP 38  I 
ATOM 270  O O   . ILE A 1 38  ? -14.599 -4.841  -4.917  1.0 91.81 ? 38  ILE A O   1 Q8R3G1 UNP 38  I 
ATOM 271  C CG1 . ILE A 1 38  ? -14.379 -1.999  -8.661  1.0 91.81 ? 38  ILE A CG1 1 Q8R3G1 UNP 38  I 
ATOM 272  C CG2 . ILE A 1 38  ? -13.035 -3.938  -7.744  1.0 91.81 ? 38  ILE A CG2 1 Q8R3G1 UNP 38  I 
ATOM 273  C CD1 . ILE A 1 38  ? -15.470 -2.813  -9.377  1.0 91.81 ? 38  ILE A CD1 1 Q8R3G1 UNP 38  I 
ATOM 274  N N   . GLU A 1 39  ? -13.598 -2.928  -4.284  1.0 92.04 ? 39  GLU A N   1 Q8R3G1 UNP 39  E 
ATOM 275  C CA  . GLU A 1 39  ? -12.978 -3.461  -3.075  1.0 92.04 ? 39  GLU A CA  1 Q8R3G1 UNP 39  E 
ATOM 276  C C   . GLU A 1 39  ? -12.566 -2.339  -2.118  1.0 92.04 ? 39  GLU A C   1 Q8R3G1 UNP 39  E 
ATOM 277  C CB  . GLU A 1 39  ? -11.768 -4.351  -3.430  1.0 92.04 ? 39  GLU A CB  1 Q8R3G1 UNP 39  E 
ATOM 278  O O   . GLU A 1 39  ? -12.366 -1.198  -2.534  1.0 92.04 ? 39  GLU A O   1 Q8R3G1 UNP 39  E 
ATOM 279  C CG  . GLU A 1 39  ? -10.625 -3.627  -4.163  1.0 92.04 ? 39  GLU A CG  1 Q8R3G1 UNP 39  E 
ATOM 280  C CD  . GLU A 1 39  ? -9.493  -4.567  -4.605  1.0 92.04 ? 39  GLU A CD  1 Q8R3G1 UNP 39  E 
ATOM 281  O OE1 . GLU A 1 39  ? -8.561  -4.046  -5.259  1.0 92.04 ? 39  GLU A OE1 1 Q8R3G1 UNP 39  E 
ATOM 282  O OE2 . GLU A 1 39  ? -9.574  -5.791  -4.327  1.0 92.04 ? 39  GLU A OE2 1 Q8R3G1 UNP 39  E 
ATOM 283  N N   . LYS A 1 40  ? -12.395 -2.684  -0.838  1.0 92.45 ? 40  LYS A N   1 Q8R3G1 UNP 40  K 
ATOM 284  C CA  . LYS A 1 40  ? -11.766 -1.817  0.162   1.0 92.45 ? 40  LYS A CA  1 Q8R3G1 UNP 40  K 
ATOM 285  C C   . LYS A 1 40  ? -10.383 -2.359  0.507   1.0 92.45 ? 40  LYS A C   1 Q8R3G1 UNP 40  K 
ATOM 286  C CB  . LYS A 1 40  ? -12.654 -1.642  1.406   1.0 92.45 ? 40  LYS A CB  1 Q8R3G1 UNP 40  K 
ATOM 287  O O   . LYS A 1 40  ? -10.232 -3.540  0.816   1.0 92.45 ? 40  LYS A O   1 Q8R3G1 UNP 40  K 
ATOM 288  C CG  . LYS A 1 40  ? -14.032 -1.043  1.079   1.0 92.45 ? 40  LYS A CG  1 Q8R3G1 UNP 40  K 
ATOM 289  C CD  . LYS A 1 40  ? -14.742 -0.557  2.353   1.0 92.45 ? 40  LYS A CD  1 Q8R3G1 UNP 40  K 
ATOM 290  C CE  . LYS A 1 40  ? -16.143 0.014   2.087   1.0 92.45 ? 40  LYS A CE  1 Q8R3G1 UNP 40  K 
ATOM 291  N NZ  . LYS A 1 40  ? -16.172 1.484   1.910   1.0 92.45 ? 40  LYS A NZ  1 Q8R3G1 UNP 40  K 
ATOM 292  N N   . LEU A 1 41  ? -9.371  -1.502  0.458   1.0 92.72 ? 41  LEU A N   1 Q8R3G1 UNP 41  L 
ATOM 293  C CA  . LEU A 1 41  ? -7.980  -1.834  0.753   1.0 92.72 ? 41  LEU A CA  1 Q8R3G1 UNP 41  L 
ATOM 294  C C   . LEU A 1 41  ? -7.597  -1.251  2.111   1.0 92.72 ? 41  LEU A C   1 Q8R3G1 UNP 41  L 
ATOM 295  C CB  . LEU A 1 41  ? -7.065  -1.301  -0.359  1.0 92.72 ? 41  LEU A CB  1 Q8R3G1 UNP 41  L 
ATOM 296  O O   . LEU A 1 41  ? -7.588  -0.037  2.296   1.0 92.72 ? 41  LEU A O   1 Q8R3G1 UNP 41  L 
ATOM 297  C CG  . LEU A 1 41  ? -7.382  -1.790  -1.782  1.0 92.72 ? 41  LEU A CG  1 Q8R3G1 UNP 41  L 
ATOM 298  C CD1 . LEU A 1 41  ? -6.432  -1.106  -2.767  1.0 92.72 ? 41  LEU A CD1 1 Q8R3G1 UNP 41  L 
ATOM 299  C CD2 . LEU A 1 41  ? -7.249  -3.306  -1.903  1.0 92.72 ? 41  LEU A CD2 1 Q8R3G1 UNP 41  L 
ATOM 300  N N   . ILE A 1 42  ? -7.270  -2.111  3.069   1.0 92.41 ? 42  ILE A N   1 Q8R3G1 UNP 42  I 
ATOM 301  C CA  . ILE A 1 42  ? -6.918  -1.687  4.426   1.0 92.41 ? 42  ILE A CA  1 Q8R3G1 UNP 42  I 
ATOM 302  C C   . ILE A 1 42  ? -5.463  -1.201  4.466   1.0 92.41 ? 42  ILE A C   1 Q8R3G1 UNP 42  I 
ATOM 303  C CB  . ILE A 1 42  ? -7.193  -2.832  5.421   1.0 92.41 ? 42  ILE A CB  1 Q8R3G1 UNP 42  I 
ATOM 304  O O   . ILE A 1 42  ? -4.550  -1.939  4.083   1.0 92.41 ? 42  ILE A O   1 Q8R3G1 UNP 42  I 
ATOM 305  C CG1 . ILE A 1 42  ? -8.637  -3.384  5.364   1.0 92.41 ? 42  ILE A CG1 1 Q8R3G1 UNP 42  I 
ATOM 306  C CG2 . ILE A 1 42  ? -6.861  -2.363  6.838   1.0 92.41 ? 42  ILE A CG2 1 Q8R3G1 UNP 42  I 
ATOM 307  C CD1 . ILE A 1 42  ? -9.748  -2.346  5.564   1.0 92.41 ? 42  ILE A CD1 1 Q8R3G1 UNP 42  I 
ATOM 308  N N   . ILE A 1 43  ? -5.242  0.026   4.951   1.0 92.54 ? 43  ILE A N   1 Q8R3G1 UNP 43  I 
ATOM 309  C CA  . ILE A 1 43  ? -3.924  0.684   4.955   1.0 92.54 ? 43  ILE A CA  1 Q8R3G1 UNP 43  I 
ATOM 310  C C   . ILE A 1 43  ? -3.418  1.041   6.360   1.0 92.54 ? 43  ILE A C   1 Q8R3G1 UNP 43  I 
ATOM 311  C CB  . ILE A 1 43  ? -3.863  1.887   3.984   1.0 92.54 ? 43  ILE A CB  1 Q8R3G1 UNP 43  I 
ATOM 312  O O   . ILE A 1 43  ? -2.616  1.958   6.498   1.0 92.54 ? 43  ILE A O   1 Q8R3G1 UNP 43  I 
ATOM 313  C CG1 . ILE A 1 43  ? -4.884  2.975   4.367   1.0 92.54 ? 43  ILE A CG1 1 Q8R3G1 UNP 43  I 
ATOM 314  C CG2 . ILE A 1 43  ? -4.041  1.425   2.530   1.0 92.54 ? 43  ILE A CG2 1 Q8R3G1 UNP 43  I 
ATOM 315  C CD1 . ILE A 1 43  ? -4.616  4.329   3.711   1.0 92.54 ? 43  ILE A CD1 1 Q8R3G1 UNP 43  I 
ATOM 316  N N   . ASP A 1 44  ? -3.872  0.344   7.403   1.0 88.88 ? 44  ASP A N   1 Q8R3G1 UNP 44  D 
ATOM 317  C CA  . ASP A 1 44  ? -3.576  0.658   8.810   1.0 88.88 ? 44  ASP A CA  1 Q8R3G1 UNP 44  D 
ATOM 318  C C   . ASP A 1 44  ? -2.379  -0.109  9.427   1.0 88.88 ? 44  ASP A C   1 Q8R3G1 UNP 44  D 
ATOM 319  C CB  . ASP A 1 44  ? -4.849  0.538   9.650   1.0 88.88 ? 44  ASP A CB  1 Q8R3G1 UNP 44  D 
ATOM 320  O O   . ASP A 1 44  ? -1.912  0.226   10.515  1.0 88.88 ? 44  ASP A O   1 Q8R3G1 UNP 44  D 
ATOM 321  C CG  . ASP A 1 44  ? -5.490  -0.846  9.655   1.0 88.88 ? 44  ASP A CG  1 Q8R3G1 UNP 44  D 
ATOM 322  O OD1 . ASP A 1 44  ? -4.889  -1.781  9.076   1.0 88.88 ? 44  ASP A OD1 1 Q8R3G1 UNP 44  D 
ATOM 323  O OD2 . ASP A 1 44  ? -6.606  -0.919  10.220  1.0 88.88 ? 44  ASP A OD2 1 Q8R3G1 UNP 44  D 
ATOM 324  N N   . GLU A 1 45  ? -1.819  -1.106  8.737   1.0 86.72 ? 45  GLU A N   1 Q8R3G1 UNP 45  E 
ATOM 325  C CA  . GLU A 1 45  ? -0.788  -1.990  9.310   1.0 86.72 ? 45  GLU A CA  1 Q8R3G1 UNP 45  E 
ATOM 326  C C   . GLU A 1 45  ? 0.652   -1.555  8.997   1.0 86.72 ? 45  GLU A C   1 Q8R3G1 UNP 45  E 
ATOM 327  C CB  . GLU A 1 45  ? -0.973  -3.417  8.792   1.0 86.72 ? 45  GLU A CB  1 Q8R3G1 UNP 45  E 
ATOM 328  O O   . GLU A 1 45  ? 1.543   -1.627  9.856   1.0 86.72 ? 45  GLU A O   1 Q8R3G1 UNP 45  E 
ATOM 329  C CG  . GLU A 1 45  ? -2.189  -4.167  9.360   1.0 86.72 ? 45  GLU A CG  1 Q8R3G1 UNP 45  E 
ATOM 330  C CD  . GLU A 1 45  ? -2.312  -5.566  8.738   1.0 86.72 ? 45  GLU A CD  1 Q8R3G1 UNP 45  E 
ATOM 331  O OE1 . GLU A 1 45  ? -3.408  -6.156  8.789   1.0 86.72 ? 45  GLU A OE1 1 Q8R3G1 UNP 45  E 
ATOM 332  O OE2 . GLU A 1 45  ? -1.349  -5.973  8.039   1.0 86.72 ? 45  GLU A OE2 1 Q8R3G1 UNP 45  E 
ATOM 333  N N   . LYS A 1 46  ? 0.910   -1.149  7.746   1.0 89.98 ? 46  LYS A N   1 Q8R3G1 UNP 46  K 
ATOM 334  C CA  . LYS A 1 46  ? 2.253   -0.816  7.252   1.0 89.98 ? 46  LYS A CA  1 Q8R3G1 UNP 46  K 
ATOM 335  C C   . LYS A 1 46  ? 2.472   0.695   7.237   1.0 89.98 ? 46  LYS A C   1 Q8R3G1 UNP 46  K 
ATOM 336  C CB  . LYS A 1 46  ? 2.534   -1.450  5.875   1.0 89.98 ? 46  LYS A CB  1 Q8R3G1 UNP 46  K 
ATOM 337  O O   . LYS A 1 46  ? 1.556   1.494   7.091   1.0 89.98 ? 46  LYS A O   1 Q8R3G1 UNP 46  K 
ATOM 338  C CG  . LYS A 1 46  ? 2.469   -2.987  5.870   1.0 89.98 ? 46  LYS A CG  1 Q8R3G1 UNP 46  K 
ATOM 339  C CD  . LYS A 1 46  ? 2.873   -3.552  4.498   1.0 89.98 ? 46  LYS A CD  1 Q8R3G1 UNP 46  K 
ATOM 340  C CE  . LYS A 1 46  ? 2.818   -5.087  4.498   1.0 89.98 ? 46  LYS A CE  1 Q8R3G1 UNP 46  K 
ATOM 341  N NZ  . LYS A 1 46  ? 3.249   -5.652  3.194   1.0 89.98 ? 46  LYS A NZ  1 Q8R3G1 UNP 46  K 
ATOM 342  N N   . LYS A 1 47  ? 3.741   1.090   7.362   1.0 91.50 ? 47  LYS A N   1 Q8R3G1 UNP 47  K 
ATOM 343  C CA  . LYS A 1 47  ? 4.178   2.494   7.258   1.0 91.50 ? 47  LYS A CA  1 Q8R3G1 UNP 47  K 
ATOM 344  C C   . LYS A 1 47  ? 4.115   3.039   5.823   1.0 91.50 ? 47  LYS A C   1 Q8R3G1 UNP 47  K 
ATOM 345  C CB  . LYS A 1 47  ? 5.573   2.656   7.891   1.0 91.50 ? 47  LYS A CB  1 Q8R3G1 UNP 47  K 
ATOM 346  O O   . LYS A 1 47  ? 4.013   4.250   5.629   1.0 91.50 ? 47  LYS A O   1 Q8R3G1 UNP 47  K 
ATOM 347  C CG  . LYS A 1 47  ? 6.617   1.677   7.323   1.0 91.50 ? 47  LYS A CG  1 Q8R3G1 UNP 47  K 
ATOM 348  C CD  . LYS A 1 47  ? 8.027   1.934   7.870   1.0 91.50 ? 47  LYS A CD  1 Q8R3G1 UNP 47  K 
ATOM 349  C CE  . LYS A 1 47  ? 9.032   1.026   7.143   1.0 91.50 ? 47  LYS A CE  1 Q8R3G1 UNP 47  K 
ATOM 350  N NZ  . LYS A 1 47  ? 10.440  1.396   7.442   1.0 91.50 ? 47  LYS A NZ  1 Q8R3G1 UNP 47  K 
ATOM 351  N N   . TYR A 1 48  ? 4.196   2.146   4.838   1.0 94.04 ? 48  TYR A N   1 Q8R3G1 UNP 48  Y 
ATOM 352  C CA  . TYR A 1 48  ? 4.016   2.443   3.424   1.0 94.04 ? 48  TYR A CA  1 Q8R3G1 UNP 48  Y 
ATOM 353  C C   . TYR A 1 48  ? 3.363   1.254   2.709   1.0 94.04 ? 48  TYR A C   1 Q8R3G1 UNP 48  Y 
ATOM 354  C CB  . TYR A 1 48  ? 5.358   2.823   2.766   1.0 94.04 ? 48  TYR A CB  1 Q8R3G1 UNP 48  Y 
ATOM 355  O O   . TYR A 1 48  ? 3.455   0.126   3.195   1.0 94.04 ? 48  TYR A O   1 Q8R3G1 UNP 48  Y 
ATOM 356  C CG  . TYR A 1 48  ? 6.340   1.677   2.585   1.0 94.04 ? 48  TYR A CG  1 Q8R3G1 UNP 48  Y 
ATOM 357  C CD1 . TYR A 1 48  ? 7.358   1.453   3.530   1.0 94.04 ? 48  TYR A CD1 1 Q8R3G1 UNP 48  Y 
ATOM 358  C CD2 . TYR A 1 48  ? 6.241   0.839   1.458   1.0 94.04 ? 48  TYR A CD2 1 Q8R3G1 UNP 48  Y 
ATOM 359  C CE1 . TYR A 1 48  ? 8.245   0.366   3.379   1.0 94.04 ? 48  TYR A CE1 1 Q8R3G1 UNP 48  Y 
ATOM 360  C CE2 . TYR A 1 48  ? 7.123   -0.245  1.300   1.0 94.04 ? 48  TYR A CE2 1 Q8R3G1 UNP 48  Y 
ATOM 361  O OH  . TYR A 1 48  ? 8.973   -1.533  2.093   1.0 94.04 ? 48  TYR A OH  1 Q8R3G1 UNP 48  Y 
ATOM 362  C CZ  . TYR A 1 48  ? 8.121   -0.489  2.261   1.0 94.04 ? 48  TYR A CZ  1 Q8R3G1 UNP 48  Y 
ATOM 363  N N   . TYR A 1 49  ? 2.749   1.526   1.561   1.0 95.05 ? 49  TYR A N   1 Q8R3G1 UNP 49  Y 
ATOM 364  C CA  . TYR A 1 49  ? 2.157   0.546   0.656   1.0 95.05 ? 49  TYR A CA  1 Q8R3G1 UNP 49  Y 
ATOM 365  C C   . TYR A 1 49  ? 2.559   0.852   -0.783  1.0 95.05 ? 49  TYR A C   1 Q8R3G1 UNP 49  Y 
ATOM 366  C CB  . TYR A 1 49  ? 0.633   0.563   0.784   1.0 95.05 ? 49  TYR A CB  1 Q8R3G1 UNP 49  Y 
ATOM 367  O O   . TYR A 1 49  ? 2.555   2.012   -1.198  1.0 95.05 ? 49  TYR A O   1 Q8R3G1 UNP 49  Y 
ATOM 368  C CG  . TYR A 1 49  ? 0.129   0.021   2.102   1.0 95.05 ? 49  TYR A CG  1 Q8R3G1 UNP 49  Y 
ATOM 369  C CD1 . TYR A 1 49  ? -0.167  -1.348  2.209   1.0 95.05 ? 49  TYR A CD1 1 Q8R3G1 UNP 49  Y 
ATOM 370  C CD2 . TYR A 1 49  ? -0.040  0.871   3.213   1.0 95.05 ? 49  TYR A CD2 1 Q8R3G1 UNP 49  Y 
ATOM 371  C CE1 . TYR A 1 49  ? -0.662  -1.873  3.413   1.0 95.05 ? 49  TYR A CE1 1 Q8R3G1 UNP 49  Y 
ATOM 372  C CE2 . TYR A 1 49  ? -0.494  0.341   4.437   1.0 95.05 ? 49  TYR A CE2 1 Q8R3G1 UNP 49  Y 
ATOM 373  O OH  . TYR A 1 49  ? -1.312  -1.554  5.681   1.0 95.05 ? 49  TYR A OH  1 Q8R3G1 UNP 49  Y 
ATOM 374  C CZ  . TYR A 1 49  ? -0.824  -1.028  4.529   1.0 95.05 ? 49  TYR A CZ  1 Q8R3G1 UNP 49  Y 
ATOM 375  N N   . LEU A 1 50  ? 2.898   -0.179  -1.548  1.0 95.13 ? 50  LEU A N   1 Q8R3G1 UNP 50  L 
ATOM 376  C CA  . LEU A 1 50  ? 3.273   -0.053  -2.954  1.0 95.13 ? 50  LEU A CA  1 Q8R3G1 UNP 50  L 
ATOM 377  C C   . LEU A 1 50  ? 2.106   -0.399  -3.878  1.0 95.13 ? 50  LEU A C   1 Q8R3G1 UNP 50  L 
ATOM 378  C CB  . LEU A 1 50  ? 4.509   -0.918  -3.233  1.0 95.13 ? 50  LEU A CB  1 Q8R3G1 UNP 50  L 
ATOM 379  O O   . LEU A 1 50  ? 1.424   -1.405  -3.696  1.0 95.13 ? 50  LEU A O   1 Q8R3G1 UNP 50  L 
ATOM 380  C CG  . LEU A 1 50  ? 5.793   -0.430  -2.541  1.0 95.13 ? 50  LEU A CG  1 Q8R3G1 UNP 50  L 
ATOM 381  C CD1 . LEU A 1 50  ? 6.927   -1.417  -2.804  1.0 95.13 ? 50  LEU A CD1 1 Q8R3G1 UNP 50  L 
ATOM 382  C CD2 . LEU A 1 50  ? 6.239   0.946   -3.038  1.0 95.13 ? 50  LEU A CD2 1 Q8R3G1 UNP 50  L 
ATOM 383  N N   . PHE A 1 51  ? 1.931   0.432   -4.901  1.0 95.94 ? 51  PHE A N   1 Q8R3G1 UNP 51  F 
ATOM 384  C CA  . PHE A 1 51  ? 0.924   0.291   -5.942  1.0 95.94 ? 51  PHE A CA  1 Q8R3G1 UNP 51  F 
ATOM 385  C C   . PHE A 1 51  ? 1.600   0.004   -7.273  1.0 95.94 ? 51  PHE A C   1 Q8R3G1 UNP 51  F 
ATOM 386  C CB  . PHE A 1 51  ? 0.118   1.589   -6.039  1.0 95.94 ? 51  PHE A CB  1 Q8R3G1 UNP 51  F 
ATOM 387  O O   . PHE A 1 51  ? 2.506   0.736   -7.680  1.0 95.94 ? 51  PHE A O   1 Q8R3G1 UNP 51  F 
ATOM 388  C CG  . PHE A 1 51  ? -0.842  1.786   -4.895  1.0 95.94 ? 51  PHE A CG  1 Q8R3G1 UNP 51  F 
ATOM 389  C CD1 . PHE A 1 51  ? -2.166  1.319   -4.994  1.0 95.94 ? 51  PHE A CD1 1 Q8R3G1 UNP 51  F 
ATOM 390  C CD2 . PHE A 1 51  ? -0.382  2.364   -3.699  1.0 95.94 ? 51  PHE A CD2 1 Q8R3G1 UNP 51  F 
ATOM 391  C CE1 . PHE A 1 51  ? -3.034  1.431   -3.896  1.0 95.94 ? 51  PHE A CE1 1 Q8R3G1 UNP 51  F 
ATOM 392  C CE2 . PHE A 1 51  ? -1.242  2.434   -2.594  1.0 95.94 ? 51  PHE A CE2 1 Q8R3G1 UNP 51  F 
ATOM 393  C CZ  . PHE A 1 51  ? -2.564  1.984   -2.695  1.0 95.94 ? 51  PHE A CZ  1 Q8R3G1 UNP 51  F 
ATOM 394  N N   . GLY A 1 52  ? 1.138   -1.007  -7.999  1.0 95.11 ? 52  GLY A N   1 Q8R3G1 UNP 52  G 
ATOM 395  C CA  . GLY A 1 52  ? 1.681   -1.297  -9.320  1.0 95.11 ? 52  GLY A CA  1 Q8R3G1 UNP 52  G 
ATOM 396  C C   . GLY A 1 52  ? 1.090   -2.537  -9.963  1.0 95.11 ? 52  GLY A C   1 Q8R3G1 UNP 52  G 
ATOM 397  O O   . GLY A 1 52  ? 0.250   -3.218  -9.391  1.0 95.11 ? 52  GLY A O   1 Q8R3G1 UNP 52  G 
ATOM 398  N N   . ARG A 1 53  ? 1.517   -2.830  -11.190 1.0 94.39 ? 53  ARG A N   1 Q8R3G1 UNP 53  R 
ATOM 399  C CA  . ARG A 1 53  ? 1.025   -3.992  -11.943 1.0 94.39 ? 53  ARG A CA  1 Q8R3G1 UNP 53  R 
ATOM 400  C C   . ARG A 1 53  ? 1.620   -5.325  -11.469 1.0 94.39 ? 53  ARG A C   1 Q8R3G1 UNP 53  R 
ATOM 401  C CB  . ARG A 1 53  ? 1.271   -3.739  -13.438 1.0 94.39 ? 53  ARG A CB  1 Q8R3G1 UNP 53  R 
ATOM 402  O O   . ARG A 1 53  ? 1.103   -6.370  -11.841 1.0 94.39 ? 53  ARG A O   1 Q8R3G1 UNP 53  R 
ATOM 403  C CG  . ARG A 1 53  ? 0.379   -4.605  -14.340 1.0 94.39 ? 53  ARG A CG  1 Q8R3G1 UNP 53  R 
ATOM 404  C CD  . ARG A 1 53  ? 0.638   -4.297  -15.816 1.0 94.39 ? 53  ARG A CD  1 Q8R3G1 UNP 53  R 
ATOM 405  N NE  . ARG A 1 53  ? 1.897   -4.908  -16.294 1.0 94.39 ? 53  ARG A NE  1 Q8R3G1 UNP 53  R 
ATOM 406  N NH1 . ARG A 1 53  ? 2.185   -3.555  -18.125 1.0 94.39 ? 53  ARG A NH1 1 Q8R3G1 UNP 53  R 
ATOM 407  N NH2 . ARG A 1 53  ? 3.562   -5.285  -17.801 1.0 94.39 ? 53  ARG A NH2 1 Q8R3G1 UNP 53  R 
ATOM 408  C CZ  . ARG A 1 53  ? 2.541   -4.579  -17.399 1.0 94.39 ? 53  ARG A CZ  1 Q8R3G1 UNP 53  R 
ATOM 409  N N   . ASN A 1 54  ? 2.738   -5.310  -10.732 1.0 91.93 ? 54  ASN A N   1 Q8R3G1 UNP 54  N 
ATOM 410  C CA  . ASN A 1 54  ? 3.420   -6.534  -10.309 1.0 91.93 ? 54  ASN A CA  1 Q8R3G1 UNP 54  N 
ATOM 411  C C   . ASN A 1 54  ? 3.020   -6.951  -8.874  1.0 91.93 ? 54  ASN A C   1 Q8R3G1 UNP 54  N 
ATOM 412  C CB  . ASN A 1 54  ? 4.948   -6.372  -10.453 1.0 91.93 ? 54  ASN A CB  1 Q8R3G1 UNP 54  N 
ATOM 413  O O   . ASN A 1 54  ? 3.480   -6.284  -7.945  1.0 91.93 ? 54  ASN A O   1 Q8R3G1 UNP 54  N 
ATOM 414  C CG  . ASN A 1 54  ? 5.648   -7.711  -10.269 1.0 91.93 ? 54  ASN A CG  1 Q8R3G1 UNP 54  N 
ATOM 415  N ND2 . ASN A 1 54  ? 6.955   -7.769  -10.282 1.0 91.93 ? 54  ASN A ND2 1 Q8R3G1 UNP 54  N 
ATOM 416  O OD1 . ASN A 1 54  ? 5.026   -8.743  -10.163 1.0 91.93 ? 54  ASN A OD1 1 Q8R3G1 UNP 54  N 
ATOM 417  N N   . PRO A 1 55  ? 2.243   -8.038  -8.676  1.0 91.63 ? 55  PRO A N   1 Q8R3G1 UNP 55  P 
ATOM 418  C CA  . PRO A 1 55  ? 1.872   -8.535  -7.343  1.0 91.63 ? 55  PRO A CA  1 Q8R3G1 UNP 55  P 
ATOM 419  C C   . PRO A 1 55  ? 3.070   -8.922  -6.474  1.0 91.63 ? 55  PRO A C   1 Q8R3G1 UNP 55  P 
ATOM 420  C CB  . PRO A 1 55  ? 1.009   -9.783  -7.578  1.0 91.63 ? 55  PRO A CB  1 Q8R3G1 UNP 55  P 
ATOM 421  O O   . PRO A 1 55  ? 3.010   -8.777  -5.262  1.0 91.63 ? 55  PRO A O   1 Q8R3G1 UNP 55  P 
ATOM 422  C CG  . PRO A 1 55  ? 1.367   -10.228 -8.991  1.0 91.63 ? 55  PRO A CG  1 Q8R3G1 UNP 55  P 
ATOM 423  C CD  . PRO A 1 55  ? 1.701   -8.924  -9.701  1.0 91.63 ? 55  PRO A CD  1 Q8R3G1 UNP 55  P 
ATOM 424  N N   . ASP A 1 56  ? 4.169   -9.376  -7.077  1.0 90.08 ? 56  ASP A N   1 Q8R3G1 UNP 56  D 
ATOM 425  C CA  . ASP A 1 56  ? 5.313   -9.891  -6.313  1.0 90.08 ? 56  ASP A CA  1 Q8R3G1 UNP 56  D 
ATOM 426  C C   . ASP A 1 56  ? 6.087   -8.777  -5.591  1.0 90.08 ? 56  ASP A C   1 Q8R3G1 UNP 56  D 
ATOM 427  C CB  . ASP A 1 56  ? 6.268   -10.632 -7.260  1.0 90.08 ? 56  ASP A CB  1 Q8R3G1 UNP 56  D 
ATOM 428  O O   . ASP A 1 56  ? 6.819   -9.024  -4.636  1.0 90.08 ? 56  ASP A O   1 Q8R3G1 UNP 56  D 
ATOM 429  C CG  . ASP A 1 56  ? 5.618   -11.774 -8.046  1.0 90.08 ? 56  ASP A CG  1 Q8R3G1 UNP 56  D 
ATOM 430  O OD1 . ASP A 1 56  ? 4.640   -12.369 -7.543  1.0 90.08 ? 56  ASP A OD1 1 Q8R3G1 UNP 56  D 
ATOM 431  O OD2 . ASP A 1 56  ? 6.104   -12.013 -9.175  1.0 90.08 ? 56  ASP A OD2 1 Q8R3G1 UNP 56  D 
ATOM 432  N N   . LEU A 1 57  ? 5.963   -7.539  -6.080  1.0 88.38 ? 57  LEU A N   1 Q8R3G1 UNP 57  L 
ATOM 433  C CA  . LEU A 1 57  ? 6.694   -6.374  -5.573  1.0 88.38 ? 57  LEU A CA  1 Q8R3G1 UNP 57  L 
ATOM 434  C C   . LEU A 1 57  ? 5.787   -5.351  -4.890  1.0 88.38 ? 57  LEU A C   1 Q8R3G1 UNP 57  L 
ATOM 435  C CB  . LEU A 1 57  ? 7.439   -5.697  -6.737  1.0 88.38 ? 57  LEU A CB  1 Q8R3G1 UNP 57  L 
ATOM 436  O O   . LEU A 1 57  ? 6.284   -4.509  -4.144  1.0 88.38 ? 57  LEU A O   1 Q8R3G1 UNP 57  L 
ATOM 437  C CG  . LEU A 1 57  ? 8.476   -6.574  -7.456  1.0 88.38 ? 57  LEU A CG  1 Q8R3G1 UNP 57  L 
ATOM 438  C CD1 . LEU A 1 57  ? 9.071   -5.780  -8.628  1.0 88.38 ? 57  LEU A CD1 1 Q8R3G1 UNP 57  L 
ATOM 439  C CD2 . LEU A 1 57  ? 9.619   -7.018  -6.546  1.0 88.38 ? 57  LEU A CD2 1 Q8R3G1 UNP 57  L 
ATOM 440  N N   . CYS A 1 58  ? 4.492   -5.360  -5.202  1.0 92.19 ? 58  CYS A N   1 Q8R3G1 UNP 58  C 
ATOM 441  C CA  . CYS A 1 58  ? 3.535   -4.360  -4.746  1.0 92.19 ? 58  CYS A CA  1 Q8R3G1 UNP 58  C 
ATOM 442  C C   . CYS A 1 58  ? 2.530   -4.975  -3.778  1.0 92.19 ? 58  CYS A C   1 Q8R3G1 UNP 58  C 
ATOM 443  C CB  . CYS A 1 58  ? 2.834   -3.714  -5.948  1.0 92.19 ? 58  CYS A CB  1 Q8R3G1 UNP 58  C 
ATOM 444  O O   . CYS A 1 58  ? 2.065   -6.088  -3.985  1.0 92.19 ? 58  CYS A O   1 Q8R3G1 UNP 58  C 
ATOM 445  S SG  . CYS A 1 58  ? 4.052   -2.810  -6.946  1.0 92.19 ? 58  CYS A SG  1 Q8R3G1 UNP 58  C 
ATOM 446  N N   . ASP A 1 59  ? 2.146   -4.213  -2.757  1.0 92.28 ? 59  ASP A N   1 Q8R3G1 UNP 59  D 
ATOM 447  C CA  . ASP A 1 59  ? 1.099   -4.625  -1.820  1.0 92.28 ? 59  ASP A CA  1 Q8R3G1 UNP 59  D 
ATOM 448  C C   . ASP A 1 59  ? -0.286  -4.617  -2.475  1.0 92.28 ? 59  ASP A C   1 Q8R3G1 UNP 59  D 
ATOM 449  C CB  . ASP A 1 59  ? 1.086   -3.667  -0.628  1.0 92.28 ? 59  ASP A CB  1 Q8R3G1 UNP 59  D 
ATOM 450  O O   . ASP A 1 59  ? -1.131  -5.452  -2.160  1.0 92.28 ? 59  ASP A O   1 Q8R3G1 UNP 59  D 
ATOM 451  C CG  . ASP A 1 59  ? 2.422   -3.629  0.102   1.0 92.28 ? 59  ASP A CG  1 Q8R3G1 UNP 59  D 
ATOM 452  O OD1 . ASP A 1 59  ? 2.686   -4.566  0.890   1.0 92.28 ? 59  ASP A OD1 1 Q8R3G1 UNP 59  D 
ATOM 453  O OD2 . ASP A 1 59  ? 3.149   -2.625  -0.067  1.0 92.28 ? 59  ASP A OD2 1 Q8R3G1 UNP 59  D 
ATOM 454  N N   . PHE A 1 60  ? -0.513  -3.668  -3.386  1.0 93.92 ? 60  PHE A N   1 Q8R3G1 UNP 60  F 
ATOM 455  C CA  . PHE A 1 60  ? -1.768  -3.511  -4.105  1.0 93.92 ? 60  PHE A CA  1 Q8R3G1 UNP 60  F 
ATOM 456  C C   . PHE A 1 60  ? -1.540  -3.559  -5.611  1.0 93.92 ? 60  PHE A C   1 Q8R3G1 UNP 60  F 
ATOM 457  C CB  . PHE A 1 60  ? -2.456  -2.216  -3.671  1.0 93.92 ? 60  PHE A CB  1 Q8R3G1 UNP 60  F 
ATOM 458  O O   . PHE A 1 60  ? -0.762  -2.782  -6.181  1.0 93.92 ? 60  PHE A O   1 Q8R3G1 UNP 60  F 
ATOM 459  C CG  . PHE A 1 60  ? -2.745  -2.141  -2.184  1.0 93.92 ? 60  PHE A CG  1 Q8R3G1 UNP 60  F 
ATOM 460  C CD1 . PHE A 1 60  ? -3.517  -3.136  -1.554  1.0 93.92 ? 60  PHE A CD1 1 Q8R3G1 UNP 60  F 
ATOM 461  C CD2 . PHE A 1 60  ? -2.240  -1.073  -1.424  1.0 93.92 ? 60  PHE A CD2 1 Q8R3G1 UNP 60  F 
ATOM 462  C CE1 . PHE A 1 60  ? -3.793  -3.053  -0.178  1.0 93.92 ? 60  PHE A CE1 1 Q8R3G1 UNP 60  F 
ATOM 463  C CE2 . PHE A 1 60  ? -2.549  -0.969  -0.058  1.0 93.92 ? 60  PHE A CE2 1 Q8R3G1 UNP 60  F 
ATOM 464  C CZ  . PHE A 1 60  ? -3.321  -1.961  0.569   1.0 93.92 ? 60  PHE A CZ  1 Q8R3G1 UNP 60  F 
ATOM 465  N N   . THR A 1 61  ? -2.251  -4.475  -6.261  1.0 93.85 ? 61  THR A N   1 Q8R3G1 UNP 61  T 
ATOM 466  C CA  . THR A 1 61  ? -2.161  -4.702  -7.696  1.0 93.85 ? 61  THR A CA  1 Q8R3G1 UNP 61  T 
ATOM 467  C C   . THR A 1 61  ? -3.106  -3.793  -8.467  1.0 93.85 ? 61  THR A C   1 Q8R3G1 UNP 61  T 
ATOM 468  C CB  . THR A 1 61  ? -2.427  -6.165  -8.053  1.0 93.85 ? 61  THR A CB  1 Q8R3G1 UNP 61  T 
ATOM 469  O O   . THR A 1 61  ? -4.306  -3.725  -8.210  1.0 93.85 ? 61  THR A O   1 Q8R3G1 UNP 61  T 
ATOM 470  C CG2 . THR A 1 61  ? -1.258  -7.039  -7.631  1.0 93.85 ? 61  THR A CG2 1 Q8R3G1 UNP 61  T 
ATOM 471  O OG1 . THR A 1 61  ? -3.554  -6.662  -7.377  1.0 93.85 ? 61  THR A OG1 1 Q8R3G1 UNP 61  T 
ATOM 472  N N   . ILE A 1 62  ? -2.562  -3.093  -9.460  1.0 94.20 ? 62  ILE A N   1 Q8R3G1 UNP 62  I 
ATOM 473  C CA  . ILE A 1 62  ? -3.338  -2.268  -10.382 1.0 94.20 ? 62  ILE A CA  1 Q8R3G1 UNP 62  I 
ATOM 474  C C   . ILE A 1 62  ? -3.445  -2.976  -11.731 1.0 94.20 ? 62  ILE A C   1 Q8R3G1 UNP 62  I 
ATOM 475  C CB  . ILE A 1 62  ? -2.764  -0.844  -10.523 1.0 94.20 ? 62  ILE A CB  1 Q8R3G1 UNP 62  I 
ATOM 476  O O   . ILE A 1 62  ? -2.463  -3.097  -12.469 1.0 94.20 ? 62  ILE A O   1 Q8R3G1 UNP 62  I 
ATOM 477  C CG1 . ILE A 1 62  ? -2.638  -0.133  -9.157  1.0 94.20 ? 62  ILE A CG1 1 Q8R3G1 UNP 62  I 
ATOM 478  C CG2 . ILE A 1 62  ? -3.716  -0.053  -11.450 1.0 94.20 ? 62  ILE A CG2 1 Q8R3G1 UNP 62  I 
ATOM 479  C CD1 . ILE A 1 62  ? -1.831  1.168   -9.231  1.0 94.20 ? 62  ILE A CD1 1 Q8R3G1 UNP 62  I 
ATOM 480  N N   . ASP A 1 63  ? -4.669  -3.355  -12.090 1.0 91.13 ? 63  ASP A N   1 Q8R3G1 UNP 63  D 
ATOM 481  C CA  . ASP A 1 63  ? -4.983  -4.040  -13.346 1.0 91.13 ? 63  ASP A CA  1 Q8R3G1 UNP 63  D 
ATOM 482  C C   . ASP A 1 63  ? -5.144  -3.053  -14.510 1.0 91.13 ? 63  ASP A C   1 Q8R3G1 UNP 63  D 
ATOM 483  C CB  . ASP A 1 63  ? -6.236  -4.909  -13.185 1.0 91.13 ? 63  ASP A CB  1 Q8R3G1 UNP 63  D 
ATOM 484  O O   . ASP A 1 63  ? -6.241  -2.844  -15.032 1.0 91.13 ? 63  ASP A O   1 Q8R3G1 UNP 63  D 
ATOM 485  C CG  . ASP A 1 63  ? -6.100  -5.967  -12.098 1.0 91.13 ? 63  ASP A CG  1 Q8R3G1 UNP 63  D 
ATOM 486  O OD1 . ASP A 1 63  ? -4.997  -6.538  -11.974 1.0 91.13 ? 63  ASP A OD1 1 Q8R3G1 UNP 63  D 
ATOM 487  O OD2 . ASP A 1 63  ? -7.126  -6.147  -11.398 1.0 91.13 ? 63  ASP A OD2 1 Q8R3G1 UNP 63  D 
ATOM 488  N N   . HIS A 1 64  ? -4.052  -2.408  -14.924 1.0 94.29 ? 64  HIS A N   1 Q8R3G1 UNP 64  H 
ATOM 489  C CA  . HIS A 1 64  ? -4.065  -1.590  -16.134 1.0 94.29 ? 64  HIS A CA  1 Q8R3G1 UNP 64  H 
ATOM 490  C C   . HIS A 1 64  ? -2.724  -1.603  -16.875 1.0 94.29 ? 64  HIS A C   1 Q8R3G1 UNP 64  H 
ATOM 491  C CB  . HIS A 1 64  ? -4.528  -0.164  -15.803 1.0 94.29 ? 64  HIS A CB  1 Q8R3G1 UNP 64  H 
ATOM 492  O O   . HIS A 1 64  ? -1.655  -1.513  -16.270 1.0 94.29 ? 64  HIS A O   1 Q8R3G1 UNP 64  H 
ATOM 493  C CG  . HIS A 1 64  ? -5.040  0.536   -17.030 1.0 94.29 ? 64  HIS A CG  1 Q8R3G1 UNP 64  H 
ATOM 494  C CD2 . HIS A 1 64  ? -6.235  0.305   -17.651 1.0 94.29 ? 64  HIS A CD2 1 Q8R3G1 UNP 64  H 
ATOM 495  N ND1 . HIS A 1 64  ? -4.366  1.459   -17.787 1.0 94.29 ? 64  HIS A ND1 1 Q8R3G1 UNP 64  H 
ATOM 496  C CE1 . HIS A 1 64  ? -5.133  1.781   -18.839 1.0 94.29 ? 64  HIS A CE1 1 Q8R3G1 UNP 64  H 
ATOM 497  N NE2 . HIS A 1 64  ? -6.268  1.078   -18.812 1.0 94.29 ? 64  HIS A NE2 1 Q8R3G1 UNP 64  H 
ATOM 498  N N   . GLN A 1 65  ? -2.762  -1.671  -18.213 1.0 94.92 ? 65  GLN A N   1 Q8R3G1 UNP 65  Q 
ATOM 499  C CA  . GLN A 1 65  ? -1.543  -1.735  -19.032 1.0 94.92 ? 65  GLN A CA  1 Q8R3G1 UNP 65  Q 
ATOM 500  C C   . GLN A 1 65  ? -0.695  -0.458  -18.956 1.0 94.92 ? 65  GLN A C   1 Q8R3G1 UNP 65  Q 
ATOM 501  C CB  . GLN A 1 65  ? -1.873  -2.075  -20.492 1.0 94.92 ? 65  GLN A CB  1 Q8R3G1 UNP 65  Q 
ATOM 502  O O   . GLN A 1 65  ? 0.526   -0.531  -19.067 1.0 94.92 ? 65  GLN A O   1 Q8R3G1 UNP 65  Q 
ATOM 503  C CG  . GLN A 1 65  ? -2.711  -1.013  -21.233 1.0 94.92 ? 65  GLN A CG  1 Q8R3G1 UNP 65  Q 
ATOM 504  C CD  . GLN A 1 65  ? -2.684  -1.192  -22.748 1.0 94.92 ? 65  GLN A CD  1 Q8R3G1 UNP 65  Q 
ATOM 505  N NE2 . GLN A 1 65  ? -3.254  -0.275  -23.496 1.0 94.92 ? 65  GLN A NE2 1 Q8R3G1 UNP 65  Q 
ATOM 506  O OE1 . GLN A 1 65  ? -2.133  -2.135  -23.288 1.0 94.92 ? 65  GLN A OE1 1 Q8R3G1 UNP 65  Q 
ATOM 507  N N   . SER A 1 66  ? -1.337  0.692   -18.719 1.0 95.06 ? 66  SER A N   1 Q8R3G1 UNP 66  S 
ATOM 508  C CA  . SER A 1 66  ? -0.659  1.984   -18.563 1.0 95.06 ? 66  SER A CA  1 Q8R3G1 UNP 66  S 
ATOM 509  C C   . SER A 1 66  ? 0.049   2.115   -17.209 1.0 95.06 ? 66  SER A C   1 Q8R3G1 UNP 66  S 
ATOM 510  C CB  . SER A 1 66  ? -1.666  3.128   -18.727 1.0 95.06 ? 66  SER A CB  1 Q8R3G1 UNP 66  S 
ATOM 511  O O   . SER A 1 66  ? 0.700   3.121   -16.943 1.0 95.06 ? 66  SER A O   1 Q8R3G1 UNP 66  S 
ATOM 512  O OG  . SER A 1 66  ? -2.356  3.327   -17.507 1.0 95.06 ? 66  SER A OG  1 Q8R3G1 UNP 66  S 
ATOM 513  N N   . CYS A 1 67  ? -0.151  1.175   -16.286 1.0 94.97 ? 67  CYS A N   1 Q8R3G1 UNP 67  C 
ATOM 514  C CA  . CYS A 1 67  ? 0.476   1.229   -14.978 1.0 94.97 ? 67  CYS A CA  1 Q8R3G1 UNP 67  C 
ATOM 515  C C   . CYS A 1 67  ? 1.811   0.485   -15.017 1.0 94.97 ? 67  CYS A C   1 Q8R3G1 UNP 67  C 
ATOM 516  C CB  . CYS A 1 67  ? -0.493  0.719   -13.906 1.0 94.97 ? 67  CYS A CB  1 Q8R3G1 UNP 67  C 
ATOM 517  O O   . CYS A 1 67  ? 1.901   -0.671  -15.439 1.0 94.97 ? 67  CYS A O   1 Q8R3G1 UNP 67  C 
ATOM 518  S SG  . CYS A 1 67  ? -1.863  1.904   -13.765 1.0 94.97 ? 67  CYS A SG  1 Q8R3G1 UNP 67  C 
ATOM 519  N N   . SER A 1 68  ? 2.864   1.160   -14.556 1.0 94.37 ? 68  SER A N   1 Q8R3G1 UNP 68  S 
ATOM 520  C CA  . SER A 1 68  ? 4.163   0.551   -14.298 1.0 94.37 ? 68  SER A CA  1 Q8R3G1 UNP 68  S 
ATOM 521  C C   . SER A 1 68  ? 4.049   -0.640  -13.337 1.0 94.37 ? 68  SER A C   1 Q8R3G1 UNP 68  S 
ATOM 522  C CB  . SER A 1 68  ? 5.113   1.604   -13.717 1.0 94.37 ? 68  SER A CB  1 Q8R3G1 UNP 68  S 
ATOM 523  O O   . SER A 1 68  ? 3.144   -0.712  -12.503 1.0 94.37 ? 68  SER A O   1 Q8R3G1 UNP 68  S 
ATOM 524  O OG  . SER A 1 68  ? 5.248   2.694   -14.609 1.0 94.37 ? 68  SER A OG  1 Q8R3G1 UNP 68  S 
ATOM 525  N N   . ARG A 1 69  ? 5.014   -1.568  -13.417 1.0 93.35 ? 69  ARG A N   1 Q8R3G1 UNP 69  R 
ATOM 526  C CA  . ARG A 1 69  ? 5.148   -2.693  -12.467 1.0 93.35 ? 69  ARG A CA  1 Q8R3G1 UNP 69  R 
ATOM 527  C C   . ARG A 1 69  ? 5.126   -2.219  -11.017 1.0 93.35 ? 69  ARG A C   1 Q8R3G1 UNP 69  R 
ATOM 528  C CB  . ARG A 1 69  ? 6.459   -3.449  -12.716 1.0 93.35 ? 69  ARG A CB  1 Q8R3G1 UNP 69  R 
ATOM 529  O O   . ARG A 1 69  ? 4.528   -2.885  -10.188 1.0 93.35 ? 69  ARG A O   1 Q8R3G1 UNP 69  R 
ATOM 530  C CG  . ARG A 1 69  ? 6.395   -4.290  -13.996 1.0 93.35 ? 69  ARG A CG  1 Q8R3G1 UNP 69  R 
ATOM 531  C CD  . ARG A 1 69  ? 7.717   -5.027  -14.234 1.0 93.35 ? 69  ARG A CD  1 Q8R3G1 UNP 69  R 
ATOM 532  N NE  . ARG A 1 69  ? 8.804   -4.105  -14.622 1.0 93.35 ? 69  ARG A NE  1 Q8R3G1 UNP 69  R 
ATOM 533  N NH1 . ARG A 1 69  ? 10.463  -5.679  -14.739 1.0 93.35 ? 69  ARG A NH1 1 Q8R3G1 UNP 69  R 
ATOM 534  N NH2 . ARG A 1 69  ? 10.922  -3.548  -15.244 1.0 93.35 ? 69  ARG A NH2 1 Q8R3G1 UNP 69  R 
ATOM 535  C CZ  . ARG A 1 69  ? 10.056  -4.446  -14.866 1.0 93.35 ? 69  ARG A CZ  1 Q8R3G1 UNP 69  R 
ATOM 536  N N   . VAL A 1 70  ? 5.747   -1.068  -10.780 1.0 94.33 ? 70  VAL A N   1 Q8R3G1 UNP 70  V 
ATOM 537  C CA  . VAL A 1 70  ? 5.778   -0.319  -9.530  1.0 94.33 ? 70  VAL A CA  1 Q8R3G1 UNP 70  V 
ATOM 538  C C   . VAL A 1 70  ? 5.492   1.119   -9.937  1.0 94.33 ? 70  VAL A C   1 Q8R3G1 UNP 70  V 
ATOM 539  C CB  . VAL A 1 70  ? 7.157   -0.452  -8.869  1.0 94.33 ? 70  VAL A CB  1 Q8R3G1 UNP 70  V 
ATOM 540  O O   . VAL A 1 70  ? 6.235   1.688   -10.734 1.0 94.33 ? 70  VAL A O   1 Q8R3G1 UNP 70  V 
ATOM 541  C CG1 . VAL A 1 70  ? 7.153   0.276   -7.524  1.0 94.33 ? 70  VAL A CG1 1 Q8R3G1 UNP 70  V 
ATOM 542  C CG2 . VAL A 1 70  ? 7.533   -1.935  -8.707  1.0 94.33 ? 70  VAL A CG2 1 Q8R3G1 UNP 70  V 
ATOM 543  N N   . HIS A 1 71  ? 4.346   1.642   -9.525  1.0 94.97 ? 71  HIS A N   1 Q8R3G1 UNP 71  H 
ATOM 544  C CA  . HIS A 1 71  ? 3.768   2.874   -10.054 1.0 94.97 ? 71  HIS A CA  1 Q8R3G1 UNP 71  H 
ATOM 545  C C   . HIS A 1 71  ? 3.871   4.012   -9.042  1.0 94.97 ? 71  HIS A C   1 Q8R3G1 UNP 71  H 
ATOM 546  C CB  . HIS A 1 71  ? 2.316   2.581   -10.460 1.0 94.97 ? 71  HIS A CB  1 Q8R3G1 UNP 71  H 
ATOM 547  O O   . HIS A 1 71  ? 4.383   5.082   -9.358  1.0 94.97 ? 71  HIS A O   1 Q8R3G1 UNP 71  H 
ATOM 548  C CG  . HIS A 1 71  ? 1.670   3.682   -11.254 1.0 94.97 ? 71  HIS A CG  1 Q8R3G1 UNP 71  H 
ATOM 549  C CD2 . HIS A 1 71  ? 1.130   4.844   -10.774 1.0 94.97 ? 71  HIS A CD2 1 Q8R3G1 UNP 71  H 
ATOM 550  N ND1 . HIS A 1 71  ? 1.485   3.685   -12.614 1.0 94.97 ? 71  HIS A ND1 1 Q8R3G1 UNP 71  H 
ATOM 551  C CE1 . HIS A 1 71  ? 0.851   4.819   -12.953 1.0 94.97 ? 71  HIS A CE1 1 Q8R3G1 UNP 71  H 
ATOM 552  N NE2 . HIS A 1 71  ? 0.583   5.535   -11.859 1.0 94.97 ? 71  HIS A NE2 1 Q8R3G1 UNP 71  H 
ATOM 553  N N   . ALA A 1 72  ? 3.425   3.766   -7.815  1.0 96.30 ? 72  ALA A N   1 Q8R3G1 UNP 72  A 
ATOM 554  C CA  . ALA A 1 72  ? 3.432   4.756   -6.751  1.0 96.30 ? 72  ALA A CA  1 Q8R3G1 UNP 72  A 
ATOM 555  C C   . ALA A 1 72  ? 3.615   4.092   -5.385  1.0 96.30 ? 72  ALA A C   1 Q8R3G1 UNP 72  A 
ATOM 556  C CB  . ALA A 1 72  ? 2.130   5.563   -6.820  1.0 96.30 ? 72  ALA A CB  1 Q8R3G1 UNP 72  A 
ATOM 557  O O   . ALA A 1 72  ? 3.338   2.904   -5.209  1.0 96.30 ? 72  ALA A O   1 Q8R3G1 UNP 72  A 
ATOM 558  N N   . ALA A 1 73  ? 4.060   4.880   -4.415  1.0 95.89 ? 73  ALA A N   1 Q8R3G1 UNP 73  A 
ATOM 559  C CA  . ALA A 1 73  ? 4.129   4.506   -3.014  1.0 95.89 ? 73  ALA A CA  1 Q8R3G1 UNP 73  A 
ATOM 560  C C   . ALA A 1 73  ? 3.214   5.412   -2.194  1.0 95.89 ? 73  ALA A C   1 Q8R3G1 UNP 73  A 
ATOM 561  C CB  . ALA A 1 73  ? 5.578   4.589   -2.529  1.0 95.89 ? 73  ALA A CB  1 Q8R3G1 UNP 73  A 
ATOM 562  O O   . ALA A 1 73  ? 3.288   6.639   -2.275  1.0 95.89 ? 73  ALA A O   1 Q8R3G1 UNP 73  A 
ATOM 563  N N   . LEU A 1 74  ? 2.376   4.802   -1.371  1.0 95.57 ? 74  LEU A N   1 Q8R3G1 UNP 74  L 
ATOM 564  C CA  . LEU A 1 74  ? 1.588   5.476   -0.355  1.0 95.57 ? 74  LEU A CA  1 Q8R3G1 UNP 74  L 
ATOM 565  C C   . LEU A 1 74  ? 2.342   5.404   0.965   1.0 95.57 ? 74  LEU A C   1 Q8R3G1 UNP 74  L 
ATOM 566  C CB  . LEU A 1 74  ? 0.241   4.766   -0.269  1.0 95.57 ? 74  LEU A CB  1 Q8R3G1 UNP 74  L 
ATOM 567  O O   . LEU A 1 74  ? 2.772   4.328   1.365   1.0 95.57 ? 74  LEU A O   1 Q8R3G1 UNP 74  L 
ATOM 568  C CG  . LEU A 1 74  ? -0.811  5.511   0.558   1.0 95.57 ? 74  LEU A CG  1 Q8R3G1 UNP 74  L 
ATOM 569  C CD1 . LEU A 1 74  ? -1.461  6.570   -0.329  1.0 95.57 ? 74  LEU A CD1 1 Q8R3G1 UNP 74  L 
ATOM 570  C CD2 . LEU A 1 74  ? -1.877  4.536   1.044   1.0 95.57 ? 74  LEU A CD2 1 Q8R3G1 UNP 74  L 
ATOM 571  N N   . VAL A 1 75  ? 2.497   6.524   1.656   1.0 95.46 ? 75  VAL A N   1 Q8R3G1 UNP 75  V 
ATOM 572  C CA  . VAL A 1 75  ? 3.261   6.603   2.902   1.0 95.46 ? 75  VAL A CA  1 Q8R3G1 UNP 75  V 
ATOM 573  C C   . VAL A 1 75  ? 2.469   7.371   3.942   1.0 95.46 ? 75  VAL A C   1 Q8R3G1 UNP 75  V 
ATOM 574  C CB  . VAL A 1 75  ? 4.624   7.274   2.683   1.0 95.46 ? 75  VAL A CB  1 Q8R3G1 UNP 75  V 
ATOM 575  O O   . VAL A 1 75  ? 1.987   8.473   3.683   1.0 95.46 ? 75  VAL A O   1 Q8R3G1 UNP 75  V 
ATOM 576  C CG1 . VAL A 1 75  ? 5.488   7.132   3.939   1.0 95.46 ? 75  VAL A CG1 1 Q8R3G1 UNP 75  V 
ATOM 577  C CG2 . VAL A 1 75  ? 5.419   6.670   1.523   1.0 95.46 ? 75  VAL A CG2 1 Q8R3G1 UNP 75  V 
ATOM 578  N N   . TYR A 1 76  ? 2.371   6.825   5.150   1.0 95.28 ? 76  TYR A N   1 Q8R3G1 UNP 76  Y 
ATOM 579  C CA  . TYR A 1 76  ? 1.721   7.517   6.254   1.0 95.28 ? 76  TYR A CA  1 Q8R3G1 UNP 76  Y 
ATOM 580  C C   . TYR A 1 76  ? 2.723   8.348   7.059   1.0 95.28 ? 76  TYR A C   1 Q8R3G1 UNP 76  Y 
ATOM 581  C CB  . TYR A 1 76  ? 0.972   6.519   7.130   1.0 95.28 ? 76  TYR A CB  1 Q8R3G1 UNP 76  Y 
ATOM 582  O O   . TYR A 1 76  ? 3.719   7.834   7.570   1.0 95.28 ? 76  TYR A O   1 Q8R3G1 UNP 76  Y 
ATOM 583  C CG  . TYR A 1 76  ? 0.215   7.222   8.233   1.0 95.28 ? 76  TYR A CG  1 Q8R3G1 UNP 76  Y 
ATOM 584  C CD1 . TYR A 1 76  ? 0.798   7.379   9.503   1.0 95.28 ? 76  TYR A CD1 1 Q8R3G1 UNP 76  Y 
ATOM 585  C CD2 . TYR A 1 76  ? -1.056  7.761   7.970   1.0 95.28 ? 76  TYR A CD2 1 Q8R3G1 UNP 76  Y 
ATOM 586  C CE1 . TYR A 1 76  ? 0.093   8.042   10.523  1.0 95.28 ? 76  TYR A CE1 1 Q8R3G1 UNP 76  Y 
ATOM 587  C CE2 . TYR A 1 76  ? -1.763  8.434   8.980   1.0 95.28 ? 76  TYR A CE2 1 Q8R3G1 UNP 76  Y 
ATOM 588  O OH  . TYR A 1 76  ? -1.892  9.157   11.257  1.0 95.28 ? 76  TYR A OH  1 Q8R3G1 UNP 76  Y 
ATOM 589  C CZ  . TYR A 1 76  ? -1.194  8.559   10.262  1.0 95.28 ? 76  TYR A CZ  1 Q8R3G1 UNP 76  Y 
ATOM 590  N N   . HIS A 1 77  ? 2.450   9.641   7.221   1.0 94.74 ? 77  HIS A N   1 Q8R3G1 UNP 77  H 
ATOM 591  C CA  . HIS A 1 77  ? 3.305   10.557  7.963   1.0 94.74 ? 77  HIS A CA  1 Q8R3G1 UNP 77  H 
ATOM 592  C C   . HIS A 1 77  ? 2.928   10.598  9.448   1.0 94.74 ? 77  HIS A C   1 Q8R3G1 UNP 77  H 
ATOM 593  C CB  . HIS A 1 77  ? 3.242   11.938  7.303   1.0 94.74 ? 77  HIS A CB  1 Q8R3G1 UNP 77  H 
ATOM 594  O O   . HIS A 1 77  ? 1.891   11.145  9.825   1.0 94.74 ? 77  HIS A O   1 Q8R3G1 UNP 77  H 
ATOM 595  C CG  . HIS A 1 77  ? 4.300   12.890  7.790   1.0 94.74 ? 77  HIS A CG  1 Q8R3G1 UNP 77  H 
ATOM 596  C CD2 . HIS A 1 77  ? 5.134   13.634  7.001   1.0 94.74 ? 77  HIS A CD2 1 Q8R3G1 UNP 77  H 
ATOM 597  N ND1 . HIS A 1 77  ? 4.647   13.139  9.099   1.0 94.74 ? 77  HIS A ND1 1 Q8R3G1 UNP 77  H 
ATOM 598  C CE1 . HIS A 1 77  ? 5.668   14.013  9.090   1.0 94.74 ? 77  HIS A CE1 1 Q8R3G1 UNP 77  H 
ATOM 599  N NE2 . HIS A 1 77  ? 5.988   14.348  7.842   1.0 94.74 ? 77  HIS A NE2 1 Q8R3G1 UNP 77  H 
ATOM 600  N N   . LYS A 1 78  ? 3.830   10.138  10.328  1.0 91.75 ? 78  LYS A N   1 Q8R3G1 UNP 78  K 
ATOM 601  C CA  . LYS A 1 78  ? 3.551   10.007  11.774  1.0 91.75 ? 78  LYS A CA  1 Q8R3G1 UNP 78  K 
ATOM 602  C C   . LYS A 1 78  ? 3.326   11.335  12.504  1.0 91.75 ? 78  LYS A C   1 Q8R3G1 UNP 78  K 
ATOM 603  C CB  . LYS A 1 78  ? 4.639   9.150   12.439  1.0 91.75 ? 78  LYS A CB  1 Q8R3G1 UNP 78  K 
ATOM 604  O O   . LYS A 1 78  ? 2.441   11.425  13.345  1.0 91.75 ? 78  LYS A O   1 Q8R3G1 UNP 78  K 
ATOM 605  C CG  . LYS A 1 78  ? 6.002   9.845   12.601  1.0 91.75 ? 78  LYS A CG  1 Q8R3G1 UNP 78  K 
ATOM 606  C CD  . LYS A 1 78  ? 7.123   8.835   12.876  1.0 91.75 ? 78  LYS A CD  1 Q8R3G1 UNP 78  K 
ATOM 607  C CE  . LYS A 1 78  ? 8.463   9.572   12.983  1.0 91.75 ? 78  LYS A CE  1 Q8R3G1 UNP 78  K 
ATOM 608  N NZ  . LYS A 1 78  ? 9.631   8.673   12.831  1.0 91.75 ? 78  LYS A NZ  1 Q8R3G1 UNP 78  K 
ATOM 609  N N   . HIS A 1 79  ? 4.103   12.372  12.172  1.0 91.06 ? 79  HIS A N   1 Q8R3G1 UNP 79  H 
ATOM 610  C CA  . HIS A 1 79  ? 3.991   13.676  12.844  1.0 91.06 ? 79  HIS A CA  1 Q8R3G1 UNP 79  H 
ATOM 611  C C   . HIS A 1 79  ? 2.793   14.502  12.364  1.0 91.06 ? 79  HIS A C   1 Q8R3G1 UNP 79  H 
ATOM 612  C CB  . HIS A 1 79  ? 5.287   14.483  12.695  1.0 91.06 ? 79  HIS A CB  1 Q8R3G1 UNP 79  H 
ATOM 613  O O   . HIS A 1 79  ? 2.118   15.124  13.174  1.0 91.06 ? 79  HIS A O   1 Q8R3G1 UNP 79  H 
ATOM 614  C CG  . HIS A 1 79  ? 6.521   13.725  13.107  1.0 91.06 ? 79  HIS A CG  1 Q8R3G1 UNP 79  H 
ATOM 615  C CD2 . HIS A 1 79  ? 7.490   13.178  12.306  1.0 91.06 ? 79  HIS A CD2 1 Q8R3G1 UNP 79  H 
ATOM 616  N ND1 . HIS A 1 79  ? 6.882   13.473  14.409  1.0 91.06 ? 79  HIS A ND1 1 Q8R3G1 UNP 79  H 
ATOM 617  C CE1 . HIS A 1 79  ? 8.043   12.804  14.399  1.0 91.06 ? 79  HIS A CE1 1 Q8R3G1 UNP 79  H 
ATOM 618  N NE2 . HIS A 1 79  ? 8.437   12.573  13.137  1.0 91.06 ? 79  HIS A NE2 1 Q8R3G1 UNP 79  H 
ATOM 619  N N   . LEU A 1 80  ? 2.515   14.491  11.056  1.0 91.76 ? 80  LEU A N   1 Q8R3G1 UNP 80  L 
ATOM 620  C CA  . LEU A 1 80  ? 1.399   15.230  10.467  1.0 91.76 ? 80  LEU A CA  1 Q8R3G1 UNP 80  L 
ATOM 621  C C   . LEU A 1 80  ? 0.061   14.492  10.560  1.0 91.76 ? 80  LEU A C   1 Q8R3G1 UNP 80  L 
ATOM 622  C CB  . LEU A 1 80  ? 1.740   15.573  9.006   1.0 91.76 ? 80  LEU A CB  1 Q8R3G1 UNP 80  L 
ATOM 623  O O   . LEU A 1 80  ? -0.968  15.120  10.339  1.0 91.76 ? 80  LEU A O   1 Q8R3G1 UNP 80  L 
ATOM 624  C CG  . LEU A 1 80  ? 2.922   16.543  8.828   1.0 91.76 ? 80  LEU A CG  1 Q8R3G1 UNP 80  L 
ATOM 625  C CD1 . LEU A 1 80  ? 3.107   16.841  7.341   1.0 91.76 ? 80  LEU A CD1 1 Q8R3G1 UNP 80  L 
ATOM 626  C CD2 . LEU A 1 80  ? 2.700   17.864  9.565   1.0 91.76 ? 80  LEU A CD2 1 Q8R3G1 UNP 80  L 
ATOM 627  N N   . LYS A 1 81  ? 0.081   13.187  10.867  1.0 90.83 ? 81  LYS A N   1 Q8R3G1 UNP 81  K 
ATOM 628  C CA  . LYS A 1 81  ? -1.081  12.285  10.841  1.0 90.83 ? 81  LYS A CA  1 Q8R3G1 UNP 81  K 
ATOM 629  C C   . LYS A 1 81  ? -1.834  12.335  9.508   1.0 90.83 ? 81  LYS A C   1 Q8R3G1 UNP 81  K 
ATOM 630  C CB  . LYS A 1 81  ? -2.006  12.531  12.042  1.0 90.83 ? 81  LYS A CB  1 Q8R3G1 UNP 81  K 
ATOM 631  O O   . LYS A 1 81  ? -3.052  12.464  9.459   1.0 90.83 ? 81  LYS A O   1 Q8R3G1 UNP 81  K 
ATOM 632  C CG  . LYS A 1 81  ? -1.318  12.347  13.400  1.0 90.83 ? 81  LYS A CG  1 Q8R3G1 UNP 81  K 
ATOM 633  C CD  . LYS A 1 81  ? -2.365  12.551  14.500  1.0 90.83 ? 81  LYS A CD  1 Q8R3G1 UNP 81  K 
ATOM 634  C CE  . LYS A 1 81  ? -1.752  12.380  15.890  1.0 90.83 ? 81  LYS A CE  1 Q8R3G1 UNP 81  K 
ATOM 635  N NZ  . LYS A 1 81  ? -2.790  12.534  16.941  1.0 90.83 ? 81  LYS A NZ  1 Q8R3G1 UNP 81  K 
ATOM 636  N N   . ARG A 1 82  ? -1.077  12.324  8.410   1.0 93.00 ? 82  ARG A N   1 Q8R3G1 UNP 82  R 
ATOM 637  C CA  . ARG A 1 82  ? -1.588  12.495  7.043   1.0 93.00 ? 82  ARG A CA  1 Q8R3G1 UNP 82  R 
ATOM 638  C C   . ARG A 1 82  ? -0.962  11.472  6.114   1.0 93.00 ? 82  ARG A C   1 Q8R3G1 UNP 82  R 
ATOM 639  C CB  . ARG A 1 82  ? -1.329  13.928  6.552   1.0 93.00 ? 82  ARG A CB  1 Q8R3G1 UNP 82  R 
ATOM 640  O O   . ARG A 1 82  ? 0.187   11.076  6.308   1.0 93.00 ? 82  ARG A O   1 Q8R3G1 UNP 82  R 
ATOM 641  C CG  . ARG A 1 82  ? -2.270  14.939  7.222   1.0 93.00 ? 82  ARG A CG  1 Q8R3G1 UNP 82  R 
ATOM 642  C CD  . ARG A 1 82  ? -1.853  16.374  6.886   1.0 93.00 ? 82  ARG A CD  1 Q8R3G1 UNP 82  R 
ATOM 643  N NE  . ARG A 1 82  ? -2.662  17.389  7.589   1.0 93.00 ? 82  ARG A NE  1 Q8R3G1 UNP 82  R 
ATOM 644  N NH1 . ARG A 1 82  ? -4.630  17.211  6.401   1.0 93.00 ? 82  ARG A NH1 1 Q8R3G1 UNP 82  R 
ATOM 645  N NH2 . ARG A 1 82  ? -4.488  18.654  8.083   1.0 93.00 ? 82  ARG A NH2 1 Q8R3G1 UNP 82  R 
ATOM 646  C CZ  . ARG A 1 82  ? -3.914  17.744  7.350   1.0 93.00 ? 82  ARG A CZ  1 Q8R3G1 UNP 82  R 
ATOM 647  N N   . VAL A 1 83  ? -1.713  11.085  5.093   1.0 94.68 ? 83  VAL A N   1 Q8R3G1 UNP 83  V 
ATOM 648  C CA  . VAL A 1 83  ? -1.255  10.169  4.051   1.0 94.68 ? 83  VAL A CA  1 Q8R3G1 UNP 83  V 
ATOM 649  C C   . VAL A 1 83  ? -0.612  10.973  2.922   1.0 94.68 ? 83  VAL A C   1 Q8R3G1 UNP 83  V 
ATOM 650  C CB  . VAL A 1 83  ? -2.422  9.302   3.551   1.0 94.68 ? 83  VAL A CB  1 Q8R3G1 UNP 83  V 
ATOM 651  O O   . VAL A 1 83  ? -1.114  12.027  2.531   1.0 94.68 ? 83  VAL A O   1 Q8R3G1 UNP 83  V 
ATOM 652  C CG1 . VAL A 1 83  ? -1.937  8.287   2.521   1.0 94.68 ? 83  VAL A CG1 1 Q8R3G1 UNP 83  V 
ATOM 653  C CG2 . VAL A 1 83  ? -3.068  8.491   4.683   1.0 94.68 ? 83  VAL A CG2 1 Q8R3G1 UNP 83  V 
ATOM 654  N N   . PHE A 1 84  ? 0.510   10.483  2.409   1.0 95.81 ? 84  PHE A N   1 Q8R3G1 UNP 84  F 
ATOM 655  C CA  . PHE A 1 84  ? 1.212   11.039  1.262   1.0 95.81 ? 84  PHE A CA  1 Q8R3G1 UNP 84  F 
ATOM 656  C C   . PHE A 1 84  ? 1.299   10.004  0.145   1.0 95.81 ? 84  PHE A C   1 Q8R3G1 UNP 84  F 
ATOM 657  C CB  . PHE A 1 84  ? 2.606   11.534  1.670   1.0 95.81 ? 84  PHE A CB  1 Q8R3G1 UNP 84  F 
ATOM 658  O O   . PHE A 1 84  ? 1.491   8.819   0.404   1.0 95.81 ? 84  PHE A O   1 Q8R3G1 UNP 84  F 
ATOM 659  C CG  . PHE A 1 84  ? 2.592   12.852  2.419   1.0 95.81 ? 84  PHE A CG  1 Q8R3G1 UNP 84  F 
ATOM 660  C CD1 . PHE A 1 84  ? 2.885   14.048  1.739   1.0 95.81 ? 84  PHE A CD1 1 Q8R3G1 UNP 84  F 
ATOM 661  C CD2 . PHE A 1 84  ? 2.270   12.892  3.787   1.0 95.81 ? 84  PHE A CD2 1 Q8R3G1 UNP 84  F 
ATOM 662  C CE1 . PHE A 1 84  ? 2.864   15.276  2.420   1.0 95.81 ? 84  PHE A CE1 1 Q8R3G1 UNP 84  F 
ATOM 663  C CE2 . PHE A 1 84  ? 2.243   14.121  4.471   1.0 95.81 ? 84  PHE A CE2 1 Q8R3G1 UNP 84  F 
ATOM 664  C CZ  . PHE A 1 84  ? 2.541   15.313  3.788   1.0 95.81 ? 84  PHE A CZ  1 Q8R3G1 UNP 84  F 
ATOM 665  N N   . LEU A 1 85  ? 1.198   10.468  -1.095  1.0 96.04 ? 85  LEU A N   1 Q8R3G1 UNP 85  L 
ATOM 666  C CA  . LEU A 1 85  ? 1.421   9.686   -2.300  1.0 96.04 ? 85  LEU A CA  1 Q8R3G1 UNP 85  L 
ATOM 667  C C   . LEU A 1 85  ? 2.689   10.161  -2.987  1.0 96.04 ? 85  LEU A C   1 Q8R3G1 UNP 85  L 
ATOM 668  C CB  . LEU A 1 85  ? 0.221   9.847   -3.235  1.0 96.04 ? 85  LEU A CB  1 Q8R3G1 UNP 85  L 
ATOM 669  O O   . LEU A 1 85  ? 2.890   11.362  -3.162  1.0 96.04 ? 85  LEU A O   1 Q8R3G1 UNP 85  L 
ATOM 670  C CG  . LEU A 1 85  ? 0.104   8.809   -4.360  1.0 96.04 ? 85  LEU A CG  1 Q8R3G1 UNP 85  L 
ATOM 671  C CD1 . LEU A 1 85  ? 0.081   7.363   -3.858  1.0 96.04 ? 85  LEU A CD1 1 Q8R3G1 UNP 85  L 
ATOM 672  C CD2 . LEU A 1 85  ? -1.224  9.065   -5.061  1.0 96.04 ? 85  LEU A CD2 1 Q8R3G1 UNP 85  L 
ATOM 673  N N   . ILE A 1 86  ? 3.529   9.220   -3.386  1.0 96.05 ? 86  ILE A N   1 Q8R3G1 UNP 86  I 
ATOM 674  C CA  . ILE A 1 86  ? 4.755   9.477   -4.130  1.0 96.05 ? 86  ILE A CA  1 Q8R3G1 UNP 86  I 
ATOM 675  C C   . ILE A 1 86  ? 4.655   8.702   -5.435  1.0 96.05 ? 86  ILE A C   1 Q8R3G1 UNP 86  I 
ATOM 676  C CB  . ILE A 1 86  ? 5.991   9.056   -3.306  1.0 96.05 ? 86  ILE A CB  1 Q8R3G1 UNP 86  I 
ATOM 677  O O   . ILE A 1 86  ? 4.567   7.475   -5.423  1.0 96.05 ? 86  ILE A O   1 Q8R3G1 UNP 86  I 
ATOM 678  C CG1 . ILE A 1 86  ? 6.072   9.813   -1.961  1.0 96.05 ? 86  ILE A CG1 1 Q8R3G1 UNP 86  I 
ATOM 679  C CG2 . ILE A 1 86  ? 7.271   9.328   -4.121  1.0 96.05 ? 86  ILE A CG2 1 Q8R3G1 UNP 86  I 
ATOM 680  C CD1 . ILE A 1 86  ? 7.025   9.177   -0.947  1.0 96.05 ? 86  ILE A CD1 1 Q8R3G1 UNP 86  I 
ATOM 681  N N   . ASP A 1 87  ? 4.686   9.407   -6.560  1.0 96.34 ? 87  ASP A N   1 Q8R3G1 UNP 87  D 
ATOM 682  C CA  . ASP A 1 87  ? 4.812   8.767   -7.865  1.0 96.34 ? 87  ASP A CA  1 Q8R3G1 UNP 87  D 
ATOM 683  C C   . ASP A 1 87  ? 6.256   8.277   -8.054  1.0 96.34 ? 87  ASP A C   1 Q8R3G1 UNP 87  D 
ATOM 684  C CB  . ASP A 1 87  ? 4.358   9.745   -8.951  1.0 96.34 ? 87  ASP A CB  1 Q8R3G1 UNP 87  D 
ATOM 685  O O   . ASP A 1 87  ? 7.208   9.047   -7.911  1.0 96.34 ? 87  ASP A O   1 Q8R3G1 UNP 87  D 
ATOM 686  C CG  . ASP A 1 87  ? 4.416   9.092   -10.328 1.0 96.34 ? 87  ASP A CG  1 Q8R3G1 UNP 87  D 
ATOM 687  O OD1 . ASP A 1 87  ? 3.424   8.420   -10.689 1.0 96.34 ? 87  ASP A OD1 1 Q8R3G1 UNP 87  D 
ATOM 688  O OD2 . ASP A 1 87  ? 5.445   9.211   -11.022 1.0 96.34 ? 87  ASP A OD2 1 Q8R3G1 UNP 87  D 
ATOM 689  N N   . LEU A 1 88  ? 6.433   6.986   -8.345  1.0 94.52 ? 88  LEU A N   1 Q8R3G1 UNP 88  L 
ATOM 690  C CA  . LEU A 1 88  ? 7.749   6.350   -8.491  1.0 94.52 ? 88  LEU A CA  1 Q8R3G1 UNP 88  L 
ATOM 691  C C   . LEU A 1 88  ? 8.229   6.411   -9.941  1.0 94.52 ? 88  LEU A C   1 Q8R3G1 UNP 88  L 
ATOM 692  C CB  . LEU A 1 88  ? 7.737   4.931   -7.891  1.0 94.52 ? 88  LEU A CB  1 Q8R3G1 UNP 88  L 
ATOM 693  O O   . LEU A 1 88  ? 8.664   5.413   -10.515 1.0 94.52 ? 88  LEU A O   1 Q8R3G1 UNP 88  L 
ATOM 694  C CG  . LEU A 1 88  ? 7.440   4.884   -6.383  1.0 94.52 ? 88  LEU A CG  1 Q8R3G1 UNP 88  L 
ATOM 695  C CD1 . LEU A 1 88  ? 7.442   3.433   -5.908  1.0 94.52 ? 88  LEU A CD1 1 Q8R3G1 UNP 88  L 
ATOM 696  C CD2 . LEU A 1 88  ? 8.453   5.666   -5.548  1.0 94.52 ? 88  LEU A CD2 1 Q8R3G1 UNP 88  L 
ATOM 697  N N   . ASN A 1 89  ? 8.116   7.604   -10.527 1.0 93.89 ? 89  ASN A N   1 Q8R3G1 UNP 89  N 
ATOM 698  C CA  . ASN A 1 89  ? 8.442   7.890   -11.916 1.0 93.89 ? 89  ASN A CA  1 Q8R3G1 UNP 89  N 
ATOM 699  C C   . ASN A 1 89  ? 7.649   7.000   -12.885 1.0 93.89 ? 89  ASN A C   1 Q8R3G1 UNP 89  N 
ATOM 700  C CB  . ASN A 1 89  ? 9.968   7.864   -12.069 1.0 93.89 ? 89  ASN A CB  1 Q8R3G1 UNP 89  N 
ATOM 701  O O   . ASN A 1 89  ? 8.200   6.331   -13.768 1.0 93.89 ? 89  ASN A O   1 Q8R3G1 UNP 89  N 
ATOM 702  C CG  . ASN A 1 89  ? 10.429  8.755   -13.192 1.0 93.89 ? 89  ASN A CG  1 Q8R3G1 UNP 89  N 
ATOM 703  N ND2 . ASN A 1 89  ? 10.623  8.210   -14.366 1.0 93.89 ? 89  ASN A ND2 1 Q8R3G1 UNP 89  N 
ATOM 704  O OD1 . ASN A 1 89  ? 10.576  9.955   -13.041 1.0 93.89 ? 89  ASN A OD1 1 Q8R3G1 UNP 89  N 
ATOM 705  N N   . SER A 1 90  ? 6.333   6.955   -12.674 1.0 94.27 ? 90  SER A N   1 Q8R3G1 UNP 90  S 
ATOM 706  C CA  . SER A 1 90  ? 5.443   6.112   -13.459 1.0 94.27 ? 90  SER A CA  1 Q8R3G1 UNP 90  S 
ATOM 707  C C   . SER A 1 90  ? 5.319   6.616   -14.900 1.0 94.27 ? 90  SER A C   1 Q8R3G1 UNP 90  S 
ATOM 708  C CB  . SER A 1 90  ? 4.081   5.985   -12.786 1.0 94.27 ? 90  SER A CB  1 Q8R3G1 UNP 90  S 
ATOM 709  O O   . SER A 1 90  ? 5.384   7.812   -15.179 1.0 94.27 ? 90  SER A O   1 Q8R3G1 UNP 90  S 
ATOM 710  O OG  . SER A 1 90  ? 3.334   7.161   -12.938 1.0 94.27 ? 90  SER A OG  1 Q8R3G1 UNP 90  S 
ATOM 711  N N   . THR A 1 91  ? 5.107   5.700   -15.852 1.0 95.30 ? 91  THR A N   1 Q8R3G1 UNP 91  T 
ATOM 712  C CA  . THR A 1 91  ? 5.081   6.048   -17.285 1.0 95.30 ? 91  THR A CA  1 Q8R3G1 UNP 91  T 
ATOM 713  C C   . THR A 1 91  ? 3.960   7.030   -17.633 1.0 95.30 ? 91  THR A C   1 Q8R3G1 UNP 91  T 
ATOM 714  C CB  . THR A 1 91  ? 4.935   4.772   -18.126 1.0 95.30 ? 91  THR A CB  1 Q8R3G1 UNP 91  T 
ATOM 715  O O   . THR A 1 91  ? 4.157   7.935   -18.439 1.0 95.30 ? 91  THR A O   1 Q8R3G1 UNP 91  T 
ATOM 716  C CG2 . THR A 1 91  ? 5.005   5.016   -19.632 1.0 95.30 ? 91  THR A CG2 1 Q8R3G1 UNP 91  T 
ATOM 717  O OG1 . THR A 1 91  ? 5.970   3.871   -17.802 1.0 95.30 ? 91  THR A OG1 1 Q8R3G1 UNP 91  T 
ATOM 718  N N   . HIS A 1 92  ? 2.786   6.870   -17.021 1.0 95.94 ? 92  HIS A N   1 Q8R3G1 UNP 92  H 
ATOM 719  C CA  . HIS A 1 92  ? 1.605   7.689   -17.311 1.0 95.94 ? 92  HIS A CA  1 Q8R3G1 UNP 92  H 
ATOM 720  C C   . HIS A 1 92  ? 1.291   8.728   -16.224 1.0 95.94 ? 92  HIS A C   1 Q8R3G1 UNP 92  H 
ATOM 721  C CB  . HIS A 1 92  ? 0.425   6.764   -17.618 1.0 95.94 ? 92  HIS A CB  1 Q8R3G1 UNP 92  H 
ATOM 722  O O   . HIS A 1 92  ? 0.397   9.550   -16.418 1.0 95.94 ? 92  HIS A O   1 Q8R3G1 UNP 92  H 
ATOM 723  C CG  . HIS A 1 92  ? 0.564   6.066   -18.948 1.0 95.94 ? 92  HIS A CG  1 Q8R3G1 UNP 92  H 
ATOM 724  C CD2 . HIS A 1 92  ? 1.262   4.920   -19.217 1.0 95.94 ? 92  HIS A CD2 1 Q8R3G1 UNP 92  H 
ATOM 725  N ND1 . HIS A 1 92  ? 0.026   6.490   -20.140 1.0 95.94 ? 92  HIS A ND1 1 Q8R3G1 UNP 92  H 
ATOM 726  C CE1 . HIS A 1 92  ? 0.363   5.603   -21.091 1.0 95.94 ? 92  HIS A CE1 1 Q8R3G1 UNP 92  H 
ATOM 727  N NE2 . HIS A 1 92  ? 1.091   4.608   -20.566 1.0 95.94 ? 92  HIS A NE2 1 Q8R3G1 UNP 92  H 
ATOM 728  N N   . GLY A 1 93  ? 2.046   8.741   -15.124 1.0 95.66 ? 93  GLY A N   1 Q8R3G1 UNP 93  G 
ATOM 729  C CA  . GLY A 1 93  ? 1.803   9.605   -13.977 1.0 95.66 ? 93  GLY A CA  1 Q8R3G1 UNP 93  G 
ATOM 730  C C   . GLY A 1 93  ? 0.698   9.097   -13.050 1.0 95.66 ? 93  GLY A C   1 Q8R3G1 UNP 93  G 
ATOM 731  O O   . GLY A 1 93  ? -0.159  8.294   -13.426 1.0 95.66 ? 93  GLY A O   1 Q8R3G1 UNP 93  G 
ATOM 732  N N   . THR A 1 94  ? 0.715   9.639   -11.838 1.0 97.13 ? 94  THR A N   1 Q8R3G1 UNP 94  T 
ATOM 733  C CA  . THR A 1 94  ? -0.327  9.479   -10.823 1.0 97.13 ? 94  THR A CA  1 Q8R3G1 UNP 94  T 
ATOM 734  C C   . THR A 1 94  ? -1.143  10.768  -10.722 1.0 97.13 ? 94  THR A C   1 Q8R3G1 UNP 94  T 
ATOM 735  C CB  . THR A 1 94  ? 0.319   9.126   -9.480  1.0 97.13 ? 94  THR A CB  1 Q8R3G1 UNP 94  T 
ATOM 736  O O   . THR A 1 94  ? -0.592  11.860  -10.858 1.0 97.13 ? 94  THR A O   1 Q8R3G1 UNP 94  T 
ATOM 737  C CG2 . THR A 1 94  ? -0.713  8.875   -8.392  1.0 97.13 ? 94  THR A CG2 1 Q8R3G1 UNP 94  T 
ATOM 738  O OG1 . THR A 1 94  ? 1.064   7.934   -9.570  1.0 97.13 ? 94  THR A OG1 1 Q8R3G1 UNP 94  T 
ATOM 739  N N   . PHE A 1 95  ? -2.445  10.664  -10.471 1.0 96.73 ? 95  PHE A N   1 Q8R3G1 UNP 95  F 
ATOM 740  C CA  . PHE A 1 95  ? -3.374  11.791  -10.415 1.0 96.73 ? 95  PHE A CA  1 Q8R3G1 UNP 95  F 
ATOM 741  C C   . PHE A 1 95  ? -4.083  11.841  -9.058  1.0 96.73 ? 95  PHE A C   1 Q8R3G1 UNP 95  F 
ATOM 742  C CB  . PHE A 1 95  ? -4.380  11.700  -11.574 1.0 96.73 ? 95  PHE A CB  1 Q8R3G1 UNP 95  F 
ATOM 743  O O   . PHE A 1 95  ? -4.539  10.818  -8.554  1.0 96.73 ? 95  PHE A O   1 Q8R3G1 UNP 95  F 
ATOM 744  C CG  . PHE A 1 95  ? -3.751  11.713  -12.958 1.0 96.73 ? 95  PHE A CG  1 Q8R3G1 UNP 95  F 
ATOM 745  C CD1 . PHE A 1 95  ? -3.674  12.912  -13.692 1.0 96.73 ? 95  PHE A CD1 1 Q8R3G1 UNP 95  F 
ATOM 746  C CD2 . PHE A 1 95  ? -3.245  10.523  -13.517 1.0 96.73 ? 95  PHE A CD2 1 Q8R3G1 UNP 95  F 
ATOM 747  C CE1 . PHE A 1 95  ? -3.091  12.920  -14.973 1.0 96.73 ? 95  PHE A CE1 1 Q8R3G1 UNP 95  F 
ATOM 748  C CE2 . PHE A 1 95  ? -2.640  10.537  -14.785 1.0 96.73 ? 95  PHE A CE2 1 Q8R3G1 UNP 95  F 
ATOM 749  C CZ  . PHE A 1 95  ? -2.563  11.735  -15.515 1.0 96.73 ? 95  PHE A CZ  1 Q8R3G1 UNP 95  F 
ATOM 750  N N   . LEU A 1 96  ? -4.196  13.033  -8.474  1.0 95.85 ? 96  LEU A N   1 Q8R3G1 UNP 96  L 
ATOM 751  C CA  . LEU A 1 96  ? -5.038  13.328  -7.315  1.0 95.85 ? 96  LEU A CA  1 Q8R3G1 UNP 96  L 
ATOM 752  C C   . LEU A 1 96  ? -6.224  14.168  -7.806  1.0 95.85 ? 96  LEU A C   1 Q8R3G1 UNP 96  L 
ATOM 753  C CB  . LEU A 1 96  ? -4.182  14.031  -6.247  1.0 95.85 ? 96  LEU A CB  1 Q8R3G1 UNP 96  L 
ATOM 754  O O   . LEU A 1 96  ? -6.068  15.337  -8.166  1.0 95.85 ? 96  LEU A O   1 Q8R3G1 UNP 96  L 
ATOM 755  C CG  . LEU A 1 96  ? -4.940  14.421  -4.966  1.0 95.85 ? 96  LEU A CG  1 Q8R3G1 UNP 96  L 
ATOM 756  C CD1 . LEU A 1 96  ? -5.429  13.207  -4.179  1.0 95.85 ? 96  LEU A CD1 1 Q8R3G1 UNP 96  L 
ATOM 757  C CD2 . LEU A 1 96  ? -4.013  15.215  -4.043  1.0 95.85 ? 96  LEU A CD2 1 Q8R3G1 UNP 96  L 
ATOM 758  N N   . GLY A 1 97  ? -7.400  13.552  -7.890  1.0 92.82 ? 97  GLY A N   1 Q8R3G1 UNP 97  G 
ATOM 759  C CA  . GLY A 1 97  ? -8.553  14.084  -8.607  1.0 92.82 ? 97  GLY A CA  1 Q8R3G1 UNP 97  G 
ATOM 760  C C   . GLY A 1 97  ? -8.204  14.302  -10.078 1.0 92.82 ? 97  GLY A C   1 Q8R3G1 UNP 97  G 
ATOM 761  O O   . GLY A 1 97  ? -7.887  13.362  -10.801 1.0 92.82 ? 97  GLY A O   1 Q8R3G1 UNP 97  G 
ATOM 762  N N   . HIS A 1 98  ? -8.207  15.562  -10.506 1.0 91.72 ? 98  HIS A N   1 Q8R3G1 UNP 98  H 
ATOM 763  C CA  . HIS A 1 98  ? -7.852  15.963  -11.873 1.0 91.72 ? 98  HIS A CA  1 Q8R3G1 UNP 98  H 
ATOM 764  C C   . HIS A 1 98  ? -6.408  16.480  -12.002 1.0 91.72 ? 98  HIS A C   1 Q8R3G1 UNP 98  H 
ATOM 765  C CB  . HIS A 1 98  ? -8.875  16.996  -12.360 1.0 91.72 ? 98  HIS A CB  1 Q8R3G1 UNP 98  H 
ATOM 766  O O   . HIS A 1 98  ? -5.990  16.888  -13.083 1.0 91.72 ? 98  HIS A O   1 Q8R3G1 UNP 98  H 
ATOM 767  C CG  . HIS A 1 98  ? -10.298 16.536  -12.175 1.0 91.72 ? 98  HIS A CG  1 Q8R3G1 UNP 98  H 
ATOM 768  C CD2 . HIS A 1 98  ? -11.194 17.012  -11.256 1.0 91.72 ? 98  HIS A CD2 1 Q8R3G1 UNP 98  H 
ATOM 769  N ND1 . HIS A 1 98  ? -10.912 15.496  -12.837 1.0 91.72 ? 98  HIS A ND1 1 Q8R3G1 UNP 98  H 
ATOM 770  C CE1 . HIS A 1 98  ? -12.149 15.355  -12.333 1.0 91.72 ? 98  HIS A CE1 1 Q8R3G1 UNP 98  H 
ATOM 771  N NE2 . HIS A 1 98  ? -12.362 16.257  -11.364 1.0 91.72 ? 98  HIS A NE2 1 Q8R3G1 UNP 98  H 
ATOM 772  N N   . ILE A 1 99  ? -5.645  16.504  -10.904 1.0 95.42 ? 99  ILE A N   1 Q8R3G1 UNP 99  I 
ATOM 773  C CA  . ILE A 1 99  ? -4.304  17.092  -10.854 1.0 95.42 ? 99  ILE A CA  1 Q8R3G1 UNP 99  I 
ATOM 774  C C   . ILE A 1 99  ? -3.265  15.984  -10.994 1.0 95.42 ? 99  ILE A C   1 Q8R3G1 UNP 99  I 
ATOM 775  C CB  . ILE A 1 99  ? -4.113  17.914  -9.559  1.0 95.42 ? 99  ILE A CB  1 Q8R3G1 UNP 99  I 
ATOM 776  O O   . ILE A 1 99  ? -3.221  15.063  -10.179 1.0 95.42 ? 99  ILE A O   1 Q8R3G1 UNP 99  I 
ATOM 777  C CG1 . ILE A 1 99  ? -5.170  19.042  -9.469  1.0 95.42 ? 99  ILE A CG1 1 Q8R3G1 UNP 99  I 
ATOM 778  C CG2 . ILE A 1 99  ? -2.688  18.500  -9.508  1.0 95.42 ? 99  ILE A CG2 1 Q8R3G1 UNP 99  I 
ATOM 779  C CD1 . ILE A 1 99  ? -5.178  19.785  -8.128  1.0 95.42 ? 99  ILE A CD1 1 Q8R3G1 UNP 99  I 
ATOM 780  N N   . ARG A 1 100 ? -2.394  16.086  -12.002 1.0 96.08 ? 100 ARG A N   1 Q8R3G1 UNP 100 R 
ATOM 781  C CA  . ARG A 1 100 ? -1.244  15.187  -12.154 1.0 96.08 ? 100 ARG A CA  1 Q8R3G1 UNP 100 R 
ATOM 782  C C   . ARG A 1 100 ? -0.176  15.511  -11.110 1.0 96.08 ? 100 ARG A C   1 Q8R3G1 UNP 100 R 
ATOM 783  C CB  . ARG A 1 100 ? -0.690  15.279  -13.580 1.0 96.08 ? 100 ARG A CB  1 Q8R3G1 UNP 100 R 
ATOM 784  O O   . ARG A 1 100 ? 0.174   16.673  -10.923 1.0 96.08 ? 100 ARG A O   1 Q8R3G1 UNP 100 R 
ATOM 785  C CG  . ARG A 1 100 ? 0.379   14.205  -13.828 1.0 96.08 ? 100 ARG A CG  1 Q8R3G1 UNP 100 R 
ATOM 786  C CD  . ARG A 1 100 ? 0.821   14.216  -15.292 1.0 96.08 ? 100 ARG A CD  1 Q8R3G1 UNP 100 R 
ATOM 787  N NE  . ARG A 1 100 ? 1.892   13.233  -15.528 1.0 96.08 ? 100 ARG A NE  1 Q8R3G1 UNP 100 R 
ATOM 788  N NH1 . ARG A 1 100 ? 1.894   13.335  -17.820 1.0 96.08 ? 100 ARG A NH1 1 Q8R3G1 UNP 100 R 
ATOM 789  N NH2 . ARG A 1 100 ? 3.273   11.920  -16.773 1.0 96.08 ? 100 ARG A NH2 1 Q8R3G1 UNP 100 R 
ATOM 790  C CZ  . ARG A 1 100 ? 2.346   12.834  -16.702 1.0 96.08 ? 100 ARG A CZ  1 Q8R3G1 UNP 100 R 
ATOM 791  N N   . LEU A 1 101 ? 0.341   14.482  -10.452 1.0 96.15 ? 101 LEU A N   1 Q8R3G1 UNP 101 L 
ATOM 792  C CA  . LEU A 1 101 ? 1.402   14.591  -9.459  1.0 96.15 ? 101 LEU A CA  1 Q8R3G1 UNP 101 L 
ATOM 793  C C   . LEU A 1 101 ? 2.781   14.556  -10.118 1.0 96.15 ? 101 LEU A C   1 Q8R3G1 UNP 101 L 
ATOM 794  C CB  . LEU A 1 101 ? 1.257   13.476  -8.409  1.0 96.15 ? 101 LEU A CB  1 Q8R3G1 UNP 101 L 
ATOM 795  O O   . LEU A 1 101 ? 2.987   13.882  -11.128 1.0 96.15 ? 101 LEU A O   1 Q8R3G1 UNP 101 L 
ATOM 796  C CG  . LEU A 1 101 ? -0.116  13.425  -7.716  1.0 96.15 ? 101 LEU A CG  1 Q8R3G1 UNP 101 L 
ATOM 797  C CD1 . LEU A 1 101 ? -0.059  12.417  -6.570  1.0 96.15 ? 101 LEU A CD1 1 Q8R3G1 UNP 101 L 
ATOM 798  C CD2 . LEU A 1 101 ? -0.523  14.792  -7.173  1.0 96.15 ? 101 LEU A CD2 1 Q8R3G1 UNP 101 L 
ATOM 799  N N   . GLU A 1 102 ? 3.725   15.263  -9.506  1.0 96.50 ? 102 GLU A N   1 Q8R3G1 UNP 102 E 
ATOM 800  C CA  . GLU A 1 102 ? 5.125   15.252  -9.923  1.0 96.50 ? 102 GLU A CA  1 Q8R3G1 UNP 102 E 
ATOM 801  C C   . GLU A 1 102 ? 5.825   13.960  -9.463  1.0 96.50 ? 102 GLU A C   1 Q8R3G1 UNP 102 E 
ATOM 802  C CB  . GLU A 1 102 ? 5.853   16.481  -9.356  1.0 96.50 ? 102 GLU A CB  1 Q8R3G1 UNP 102 E 
ATOM 803  O O   . GLU A 1 102 ? 5.625   13.529  -8.318  1.0 96.50 ? 102 GLU A O   1 Q8R3G1 UNP 102 E 
ATOM 804  C CG  . GLU A 1 102 ? 5.386   17.811  -9.969  1.0 96.50 ? 102 GLU A CG  1 Q8R3G1 UNP 102 E 
ATOM 805  C CD  . GLU A 1 102 ? 5.662   17.920  -11.477 1.0 96.50 ? 102 GLU A CD  1 Q8R3G1 UNP 102 E 
ATOM 806  O OE1 . GLU A 1 102 ? 4.875   18.616  -12.153 1.0 96.50 ? 102 GLU A OE1 1 Q8R3G1 UNP 102 E 
ATOM 807  O OE2 . GLU A 1 102 ? 6.663   17.325  -11.932 1.0 96.50 ? 102 GLU A OE2 1 Q8R3G1 UNP 102 E 
ATOM 808  N N   . PRO A 1 103 ? 6.677   13.352  -10.308 1.0 94.80 ? 103 PRO A N   1 Q8R3G1 UNP 103 P 
ATOM 809  C CA  . PRO A 1 103 ? 7.449   12.173  -9.934  1.0 94.80 ? 103 PRO A CA  1 Q8R3G1 UNP 103 P 
ATOM 810  C C   . PRO A 1 103 ? 8.406   12.484  -8.776  1.0 94.80 ? 103 PRO A C   1 Q8R3G1 UNP 103 P 
ATOM 811  C CB  . PRO A 1 103 ? 8.169   11.733  -11.208 1.0 94.80 ? 103 PRO A CB  1 Q8R3G1 UNP 103 P 
ATOM 812  O O   . PRO A 1 103 ? 8.945   13.585  -8.664  1.0 94.80 ? 103 PRO A O   1 Q8R3G1 UNP 103 P 
ATOM 813  C CG  . PRO A 1 103 ? 8.333   13.034  -11.989 1.0 94.80 ? 103 PRO A CG  1 Q8R3G1 UNP 103 P 
ATOM 814  C CD  . PRO A 1 103 ? 7.066   13.810  -11.636 1.0 94.80 ? 103 PRO A CD  1 Q8R3G1 UNP 103 P 
ATOM 815  N N   . HIS A 1 104 ? 8.613   11.505  -7.892  1.0 91.75 ? 104 HIS A N   1 Q8R3G1 UNP 104 H 
ATOM 816  C CA  . HIS A 1 104 ? 9.483   11.576  -6.709  1.0 91.75 ? 104 HIS A CA  1 Q8R3G1 UNP 104 H 
ATOM 817  C C   . HIS A 1 104 ? 9.146   12.664  -5.676  1.0 91.75 ? 104 HIS A C   1 Q8R3G1 UNP 104 H 
ATOM 818  C CB  . HIS A 1 104 ? 10.956  11.617  -7.139  1.0 91.75 ? 104 HIS A CB  1 Q8R3G1 UNP 104 H 
ATOM 819  O O   . HIS A 1 104 ? 9.874   12.826  -4.693  1.0 91.75 ? 104 HIS A O   1 Q8R3G1 UNP 104 H 
ATOM 820  C CG  . HIS A 1 104 ? 11.379  10.369  -7.855  1.0 91.75 ? 104 HIS A CG  1 Q8R3G1 UNP 104 H 
ATOM 821  C CD2 . HIS A 1 104 ? 11.714  10.247  -9.176  1.0 91.75 ? 104 HIS A CD2 1 Q8R3G1 UNP 104 H 
ATOM 822  N ND1 . HIS A 1 104 ? 11.518  9.128   -7.278  1.0 91.75 ? 104 HIS A ND1 1 Q8R3G1 UNP 104 H 
ATOM 823  C CE1 . HIS A 1 104 ? 11.940  8.276   -8.224  1.0 91.75 ? 104 HIS A CE1 1 Q8R3G1 UNP 104 H 
ATOM 824  N NE2 . HIS A 1 104 ? 12.086  8.916   -9.392  1.0 91.75 ? 104 HIS A NE2 1 Q8R3G1 UNP 104 H 
ATOM 825  N N   . LYS A 1 105 ? 8.028   13.379  -5.834  1.0 93.95 ? 105 LYS A N   1 Q8R3G1 UNP 105 K 
ATOM 826  C CA  . LYS A 1 105 ? 7.588   14.401  -4.886  1.0 93.95 ? 105 LYS A CA  1 Q8R3G1 UNP 105 K 
ATOM 827  C C   . LYS A 1 105 ? 6.433   13.872  -4.028  1.0 93.95 ? 105 LYS A C   1 Q8R3G1 UNP 105 K 
ATOM 828  C CB  . LYS A 1 105 ? 7.226   15.665  -5.665  1.0 93.95 ? 105 LYS A CB  1 Q8R3G1 UNP 105 K 
ATOM 829  O O   . LYS A 1 105 ? 5.382   13.546  -4.575  1.0 93.95 ? 105 LYS A O   1 Q8R3G1 UNP 105 K 
ATOM 830  C CG  . LYS A 1 105 ? 7.022   16.857  -4.722  1.0 93.95 ? 105 LYS A CG  1 Q8R3G1 UNP 105 K 
ATOM 831  C CD  . LYS A 1 105 ? 6.784   18.118  -5.552  1.0 93.95 ? 105 LYS A CD  1 Q8R3G1 UNP 105 K 
ATOM 832  C CE  . LYS A 1 105 ? 6.576   19.332  -4.647  1.0 93.95 ? 105 LYS A CE  1 Q8R3G1 UNP 105 K 
ATOM 833  N NZ  . LYS A 1 105 ? 6.330   20.544  -5.465  1.0 93.95 ? 105 LYS A NZ  1 Q8R3G1 UNP 105 K 
ATOM 834  N N   . PRO A 1 106 ? 6.576   13.806  -2.691  1.0 94.51 ? 106 PRO A N   1 Q8R3G1 UNP 106 P 
ATOM 835  C CA  . PRO A 1 106 ? 5.477   13.408  -1.819  1.0 94.51 ? 106 PRO A CA  1 Q8R3G1 UNP 106 P 
ATOM 836  C C   . PRO A 1 106 ? 4.364   14.456  -1.842  1.0 94.51 ? 106 PRO A C   1 Q8R3G1 UNP 106 P 
ATOM 837  C CB  . PRO A 1 106 ? 6.098   13.223  -0.428  1.0 94.51 ? 106 PRO A CB  1 Q8R3G1 UNP 106 P 
ATOM 838  O O   . PRO A 1 106 ? 4.562   15.599  -1.429  1.0 94.51 ? 106 PRO A O   1 Q8R3G1 UNP 106 P 
ATOM 839  C CG  . PRO A 1 106 ? 7.322   14.137  -0.452  1.0 94.51 ? 106 PRO A CG  1 Q8R3G1 UNP 106 P 
ATOM 840  C CD  . PRO A 1 106 ? 7.771   14.100  -1.912  1.0 94.51 ? 106 PRO A CD  1 Q8R3G1 UNP 106 P 
ATOM 841  N N   . GLN A 1 107 ? 3.178   14.048  -2.287  1.0 95.98 ? 107 GLN A N   1 Q8R3G1 UNP 107 Q 
ATOM 842  C CA  . GLN A 1 107 ? 1.967   14.856  -2.277  1.0 95.98 ? 107 GLN A CA  1 Q8R3G1 UNP 107 Q 
ATOM 843  C C   . GLN A 1 107 ? 1.029   14.396  -1.163  1.0 95.98 ? 107 GLN A C   1 Q8R3G1 UNP 107 Q 
ATOM 844  C CB  . GLN A 1 107 ? 1.277   14.776  -3.645  1.0 95.98 ? 107 GLN A CB  1 Q8R3G1 UNP 107 Q 
ATOM 845  O O   . GLN A 1 107 ? 0.721   13.215  -1.050  1.0 95.98 ? 107 GLN A O   1 Q8R3G1 UNP 107 Q 
ATOM 846  C CG  . GLN A 1 107 ? -0.026  15.590  -3.673  1.0 95.98 ? 107 GLN A CG  1 Q8R3G1 UNP 107 Q 
ATOM 847  C CD  . GLN A 1 107 ? 0.182   17.059  -3.340  1.0 95.98 ? 107 GLN A CD  1 Q8R3G1 UNP 107 Q 
ATOM 848  N NE2 . GLN A 1 107 ? -0.574  17.585  -2.401  1.0 95.98 ? 107 GLN A NE2 1 Q8R3G1 UNP 107 Q 
ATOM 849  O OE1 . GLN A 1 107 ? 1.042   17.743  -3.869  1.0 95.98 ? 107 GLN A OE1 1 Q8R3G1 UNP 107 Q 
ATOM 850  N N   . GLN A 1 108 ? 0.525   15.331  -0.362  1.0 94.97 ? 108 GLN A N   1 Q8R3G1 UNP 108 Q 
ATOM 851  C CA  . GLN A 1 108 ? -0.464  15.026  0.667   1.0 94.97 ? 108 GLN A CA  1 Q8R3G1 UNP 108 Q 
ATOM 852  C C   . GLN A 1 108 ? -1.816  14.656  0.037   1.0 94.97 ? 108 GLN A C   1 Q8R3G1 UNP 108 Q 
ATOM 853  C CB  . GLN A 1 108 ? -0.606  16.247  1.579   1.0 94.97 ? 108 GLN A CB  1 Q8R3G1 UNP 108 Q 
ATOM 854  O O   . GLN A 1 108 ? -2.325  15.415  -0.792  1.0 94.97 ? 108 GLN A O   1 Q8R3G1 UNP 108 Q 
ATOM 855  C CG  . GLN A 1 108 ? -1.496  15.949  2.787   1.0 94.97 ? 108 GLN A CG  1 Q8R3G1 UNP 108 Q 
ATOM 856  C CD  . GLN A 1 108 ? -1.909  17.229  3.485   1.0 94.97 ? 108 GLN A CD  1 Q8R3G1 UNP 108 Q 
ATOM 857  N NE2 . GLN A 1 108 ? -3.172  17.366  3.817   1.0 94.97 ? 108 GLN A NE2 1 Q8R3G1 UNP 108 Q 
ATOM 858  O OE1 . GLN A 1 108 ? -1.128  18.115  3.777   1.0 94.97 ? 108 GLN A OE1 1 Q8R3G1 UNP 108 Q 
ATOM 859  N N   . ILE A 1 109 ? -2.417  13.556  0.499   1.0 95.12 ? 109 ILE A N   1 Q8R3G1 UNP 109 I 
ATOM 860  C CA  . ILE A 1 109 ? -3.779  13.129  0.163   1.0 95.12 ? 109 ILE A CA  1 Q8R3G1 UNP 109 I 
ATOM 861  C C   . ILE A 1 109 ? -4.703  13.462  1.348   1.0 95.12 ? 109 ILE A C   1 Q8R3G1 UNP 109 I 
ATOM 862  C CB  . ILE A 1 109 ? -3.853  11.622  -0.159  1.0 95.12 ? 109 ILE A CB  1 Q8R3G1 UNP 109 I 
ATOM 863  O O   . ILE A 1 109 ? -4.482  12.960  2.455   1.0 95.12 ? 109 ILE A O   1 Q8R3G1 UNP 109 I 
ATOM 864  C CG1 . ILE A 1 109 ? -2.790  11.164  -1.174  1.0 95.12 ? 109 ILE A CG1 1 Q8R3G1 UNP 109 I 
ATOM 865  C CG2 . ILE A 1 109 ? -5.252  11.287  -0.717  1.0 95.12 ? 109 ILE A CG2 1 Q8R3G1 UNP 109 I 
ATOM 866  C CD1 . ILE A 1 109 ? -2.735  9.633   -1.233  1.0 95.12 ? 109 ILE A CD1 1 Q8R3G1 UNP 109 I 
ATOM 867  N N   . PRO A 1 110 ? -5.703  14.336  1.171   1.0 93.75 ? 110 PRO A N   1 Q8R3G1 UNP 110 P 
ATOM 868  C CA  . PRO A 1 110 ? -6.760  14.537  2.160   1.0 93.75 ? 110 PRO A CA  1 Q8R3G1 UNP 110 P 
ATOM 869  C C   . PRO A 1 110 ? -7.677  13.308  2.273   1.0 93.75 ? 110 PRO A C   1 Q8R3G1 UNP 110 P 
ATOM 870  C CB  . PRO A 1 110 ? -7.539  15.780  1.709   1.0 93.75 ? 110 PRO A CB  1 Q8R3G1 UNP 110 P 
ATOM 871  O O   . PRO A 1 110 ? -7.791  12.524  1.334   1.0 93.75 ? 110 PRO A O   1 Q8R3G1 UNP 110 P 
ATOM 872  C CG  . PRO A 1 110 ? -6.750  16.358  0.531   1.0 93.75 ? 110 PRO A CG  1 Q8R3G1 UNP 110 P 
ATOM 873  C CD  . PRO A 1 110 ? -5.881  15.212  0.029   1.0 93.75 ? 110 PRO A CD  1 Q8R3G1 UNP 110 P 
ATOM 874  N N   . ILE A 1 111 ? -8.368  13.164  3.406   1.0 92.71 ? 111 ILE A N   1 Q8R3G1 UNP 111 I 
ATOM 875  C CA  . ILE A 1 111 ? -9.490  12.217  3.510   1.0 92.71 ? 111 ILE A CA  1 Q8R3G1 UNP 111 I 
ATOM 876  C C   . ILE A 1 111 ? -10.579 12.638  2.505   1.0 92.71 ? 111 ILE A C   1 Q8R3G1 UNP 111 I 
ATOM 877  C CB  . ILE A 1 111 ? -10.009 12.118  4.966   1.0 92.71 ? 111 ILE A CB  1 Q8R3G1 UNP 111 I 
ATOM 878  O O   . ILE A 1 111 ? -10.651 13.807  2.119   1.0 92.71 ? 111 ILE A O   1 Q8R3G1 UNP 111 I 
ATOM 879  C CG1 . ILE A 1 111 ? -8.885  11.876  6.005   1.0 92.71 ? 111 ILE A CG1 1 Q8R3G1 UNP 111 I 
ATOM 880  C CG2 . ILE A 1 111 ? -11.066 11.012  5.115   1.0 92.71 ? 111 ILE A CG2 1 Q8R3G1 UNP 111 I 
ATOM 881  C CD1 . ILE A 1 111 ? -8.045  10.609  5.791   1.0 92.71 ? 111 ILE A CD1 1 Q8R3G1 UNP 111 I 
ATOM 882  N N   . ASP A 1 112 ? -11.333 11.666  2.005   1.0 93.31 ? 112 ASP A N   1 Q8R3G1 UNP 112 D 
ATOM 883  C CA  . ASP A 1 112 ? -12.360 11.772  0.961   1.0 93.31 ? 112 ASP A CA  1 Q8R3G1 UNP 112 D 
ATOM 884  C C   . ASP A 1 112 ? -11.841 12.249  -0.400  1.0 93.31 ? 112 ASP A C   1 Q8R3G1 UNP 112 D 
ATOM 885  C CB  . ASP A 1 112 ? -13.570 12.555  1.479   1.0 93.31 ? 112 ASP A CB  1 Q8R3G1 UNP 112 D 
ATOM 886  O O   . ASP A 1 112 ? -12.600 12.538  -1.326  1.0 93.31 ? 112 ASP A O   1 Q8R3G1 UNP 112 D 
ATOM 887  C CG  . ASP A 1 112 ? -14.054 11.978  2.809   1.0 93.31 ? 112 ASP A CG  1 Q8R3G1 UNP 112 D 
ATOM 888  O OD1 . ASP A 1 112 ? -14.219 10.737  2.867   1.0 93.31 ? 112 ASP A OD1 1 Q8R3G1 UNP 112 D 
ATOM 889  O OD2 . ASP A 1 112 ? -14.173 12.774  3.766   1.0 93.31 ? 112 ASP A OD2 1 Q8R3G1 UNP 112 D 
ATOM 890  N N   . SER A 1 113 ? -10.518 12.300  -0.566  1.0 95.20 ? 113 SER A N   1 Q8R3G1 UNP 113 S 
ATOM 891  C CA  . SER A 1 113 ? -9.903  12.612  -1.849  1.0 95.20 ? 113 SER A CA  1 Q8R3G1 UNP 113 S 
ATOM 892  C C   . SER A 1 113 ? -9.706  11.362  -2.684  1.0 95.20 ? 113 SER A C   1 Q8R3G1 UNP 113 S 
ATOM 893  C CB  . SER A 1 113 ? -8.593  13.356  -1.671  1.0 95.20 ? 113 SER A CB  1 Q8R3G1 UNP 113 S 
ATOM 894  O O   . SER A 1 113 ? -9.324  10.304  -2.185  1.0 95.20 ? 113 SER A O   1 Q8R3G1 UNP 113 S 
ATOM 895  O OG  . SER A 1 113 ? -8.885  14.560  -1.000  1.0 95.20 ? 113 SER A OG  1 Q8R3G1 UNP 113 S 
ATOM 896  N N   . THR A 1 114 ? -9.934  11.521  -3.984  1.0 95.56 ? 114 THR A N   1 Q8R3G1 UNP 114 T 
ATOM 897  C CA  . THR A 1 114 ? -9.828  10.444  -4.963  1.0 95.56 ? 114 THR A CA  1 Q8R3G1 UNP 114 T 
ATOM 898  C C   . THR A 1 114 ? -8.497  10.507  -5.697  1.0 95.56 ? 114 THR A C   1 Q8R3G1 UNP 114 T 
ATOM 899  C CB  . THR A 1 114 ? -11.016 10.488  -5.925  1.0 95.56 ? 114 THR A CB  1 Q8R3G1 UNP 114 T 
ATOM 900  O O   . THR A 1 114 ? -8.064  11.572  -6.126  1.0 95.56 ? 114 THR A O   1 Q8R3G1 UNP 114 T 
ATOM 901  C CG2 . THR A 1 114 ? -10.952 9.379   -6.967  1.0 95.56 ? 114 THR A CG2 1 Q8R3G1 UNP 114 T 
ATOM 902  O OG1 . THR A 1 114 ? -12.197 10.282  -5.181  1.0 95.56 ? 114 THR A OG1 1 Q8R3G1 UNP 114 T 
ATOM 903  N N   . VAL A 1 115 ? -7.855  9.361   -5.866  1.0 96.61 ? 115 VAL A N   1 Q8R3G1 UNP 115 V 
ATOM 904  C CA  . VAL A 1 115 ? -6.592  9.168   -6.579  1.0 96.61 ? 115 VAL A CA  1 Q8R3G1 UNP 115 V 
ATOM 905  C C   . VAL A 1 115 ? -6.827  8.256   -7.780  1.0 96.61 ? 115 VAL A C   1 Q8R3G1 UNP 115 V 
ATOM 906  C CB  . VAL A 1 115 ? -5.537  8.597   -5.615  1.0 96.61 ? 115 VAL A CB  1 Q8R3G1 UNP 115 V 
ATOM 907  O O   . VAL A 1 115 ? -7.674  7.365   -7.751  1.0 96.61 ? 115 VAL A O   1 Q8R3G1 UNP 115 V 
ATOM 908  C CG1 . VAL A 1 115 ? -4.229  8.190   -6.300  1.0 96.61 ? 115 VAL A CG1 1 Q8R3G1 UNP 115 V 
ATOM 909  C CG2 . VAL A 1 115 ? -5.190  9.615   -4.522  1.0 96.61 ? 115 VAL A CG2 1 Q8R3G1 UNP 115 V 
ATOM 910  N N   . SER A 1 116 ? -6.085  8.461   -8.860  1.0 95.89 ? 116 SER A N   1 Q8R3G1 UNP 116 S 
ATOM 911  C CA  . SER A 1 116 ? -6.121  7.620   -10.057 1.0 95.89 ? 116 SER A CA  1 Q8R3G1 UNP 116 S 
ATOM 912  C C   . SER A 1 116 ? -4.708  7.379   -10.577 1.0 95.89 ? 116 SER A C   1 Q8R3G1 UNP 116 S 
ATOM 913  C CB  . SER A 1 116 ? -7.017  8.254   -11.125 1.0 95.89 ? 116 SER A CB  1 Q8R3G1 UNP 116 S 
ATOM 914  O O   . SER A 1 116 ? -3.830  8.231   -10.450 1.0 95.89 ? 116 SER A O   1 Q8R3G1 UNP 116 S 
ATOM 915  O OG  . SER A 1 116 ? -8.322  8.403   -10.603 1.0 95.89 ? 116 SER A OG  1 Q8R3G1 UNP 116 S 
ATOM 916  N N   . PHE A 1 117 ? -4.470  6.204   -11.154 1.0 96.37 ? 117 PHE A N   1 Q8R3G1 UNP 117 F 
ATOM 917  C CA  . PHE A 1 117 ? -3.137  5.777   -11.586 1.0 96.37 ? 117 PHE A CA  1 Q8R3G1 UNP 117 F 
ATOM 918  C C   . PHE A 1 117 ? -3.099  5.593   -13.101 1.0 96.37 ? 117 PHE A C   1 Q8R3G1 UNP 117 F 
ATOM 919  C CB  . PHE A 1 117 ? -2.747  4.495   -10.845 1.0 96.37 ? 117 PHE A CB  1 Q8R3G1 UNP 117 F 
ATOM 920  O O   . PHE A 1 117 ? -3.832  4.769   -13.653 1.0 96.37 ? 117 PHE A O   1 Q8R3G1 UNP 117 F 
ATOM 921  C CG  . PHE A 1 117 ? -2.682  4.643   -9.336  1.0 96.37 ? 117 PHE A CG  1 Q8R3G1 UNP 117 F 
ATOM 922  C CD1 . PHE A 1 117 ? -1.648  5.382   -8.737  1.0 96.37 ? 117 PHE A CD1 1 Q8R3G1 UNP 117 F 
ATOM 923  C CD2 . PHE A 1 117 ? -3.655  4.035   -8.524  1.0 96.37 ? 117 PHE A CD2 1 Q8R3G1 UNP 117 F 
ATOM 924  C CE1 . PHE A 1 117 ? -1.571  5.487   -7.338  1.0 96.37 ? 117 PHE A CE1 1 Q8R3G1 UNP 117 F 
ATOM 925  C CE2 . PHE A 1 117 ? -3.583  4.141   -7.124  1.0 96.37 ? 117 PHE A CE2 1 Q8R3G1 UNP 117 F 
ATOM 926  C CZ  . PHE A 1 117 ? -2.534  4.861   -6.529  1.0 96.37 ? 117 PHE A CZ  1 Q8R3G1 UNP 117 F 
ATOM 927  N N   . GLY A 1 118 ? -2.229  6.341   -13.781 1.0 94.86 ? 118 GLY A N   1 Q8R3G1 UNP 118 G 
ATOM 928  C CA  . GLY A 1 118 ? -2.140  6.359   -15.236 1.0 94.86 ? 118 GLY A CA  1 Q8R3G1 UNP 118 G 
ATOM 929  C C   . GLY A 1 118 ? -3.495  6.588   -15.911 1.0 94.86 ? 118 GLY A C   1 Q8R3G1 UNP 118 G 
ATOM 930  O O   . GLY A 1 118 ? -4.206  7.532   -15.592 1.0 94.86 ? 118 GLY A O   1 Q8R3G1 UNP 118 G 
ATOM 931  N N   . ALA A 1 119 ? -3.850  5.702   -16.839 1.0 94.43 ? 119 ALA A N   1 Q8R3G1 UNP 119 A 
ATOM 932  C CA  . ALA A 1 119 ? -5.133  5.680   -17.537 1.0 94.43 ? 119 ALA A CA  1 Q8R3G1 UNP 119 A 
ATOM 933  C C   . ALA A 1 119 ? -6.109  4.627   -16.966 1.0 94.43 ? 119 ALA A C   1 Q8R3G1 UNP 119 A 
ATOM 934  C CB  . ALA A 1 119 ? -4.847  5.514   -19.036 1.0 94.43 ? 119 ALA A CB  1 Q8R3G1 UNP 119 A 
ATOM 935  O O   . ALA A 1 119 ? -7.035  4.209   -17.655 1.0 94.43 ? 119 ALA A O   1 Q8R3G1 UNP 119 A 
ATOM 936  N N   . SER A 1 120 ? -5.890  4.159   -15.731 1.0 93.81 ? 120 SER A N   1 Q8R3G1 UNP 120 S 
ATOM 937  C CA  . SER A 1 120 ? -6.832  3.260   -15.058 1.0 93.81 ? 120 SER A CA  1 Q8R3G1 UNP 120 S 
ATOM 938  C C   . SER A 1 120 ? -8.175  3.956   -14.837 1.0 93.81 ? 120 SER A C   1 Q8R3G1 UNP 120 S 
ATOM 939  C CB  . SER A 1 120 ? -6.272  2.816   -13.707 1.0 93.81 ? 120 SER A CB  1 Q8R3G1 UNP 120 S 
ATOM 940  O O   . SER A 1 120 ? -8.222  5.097   -14.390 1.0 93.81 ? 120 SER A O   1 Q8R3G1 UNP 120 S 
ATOM 941  O OG  . SER A 1 120 ? -7.177  1.943   -13.054 1.0 93.81 ? 120 SER A OG  1 Q8R3G1 UNP 120 S 
ATOM 942  N N   . THR A 1 121 ? -9.273  3.237   -15.072 1.0 93.17 ? 121 THR A N   1 Q8R3G1 UNP 121 T 
ATOM 943  C CA  . THR A 1 121 ? -10.632 3.715   -14.771 1.0 93.17 ? 121 THR A CA  1 Q8R3G1 UNP 121 T 
ATOM 944  C C   . THR A 1 121 ? -11.015 3.541   -13.297 1.0 93.17 ? 121 THR A C   1 Q8R3G1 UNP 121 T 
ATOM 945  C CB  . THR A 1 121 ? -11.678 3.001   -15.642 1.0 93.17 ? 121 THR A CB  1 Q8R3G1 UNP 121 T 
ATOM 946  O O   . THR A 1 121 ? -12.156 3.813   -12.934 1.0 93.17 ? 121 THR A O   1 Q8R3G1 UNP 121 T 
ATOM 947  C CG2 . THR A 1 121 ? -11.388 3.094   -17.139 1.0 93.17 ? 121 THR A CG2 1 Q8R3G1 UNP 121 T 
ATOM 948  O OG1 . THR A 1 121 ? -11.743 1.635   -15.271 1.0 93.17 ? 121 THR A OG1 1 Q8R3G1 UNP 121 T 
ATOM 949  N N   . ARG A 1 122 ? -10.128 2.976   -12.464 1.0 94.34 ? 122 ARG A N   1 Q8R3G1 UNP 122 R 
ATOM 950  C CA  . ARG A 1 122 ? -10.369 2.802   -11.026 1.0 94.34 ? 122 ARG A CA  1 Q8R3G1 UNP 122 R 
ATOM 951  C C   . ARG A 1 122 ? -9.987  4.082   -10.278 1.0 94.34 ? 122 ARG A C   1 Q8R3G1 UNP 122 R 
ATOM 952  C CB  . ARG A 1 122 ? -9.625  1.584   -10.448 1.0 94.34 ? 122 ARG A CB  1 Q8R3G1 UNP 122 R 
ATOM 953  O O   . ARG A 1 122 ? -8.863  4.566   -10.416 1.0 94.34 ? 122 ARG A O   1 Q8R3G1 UNP 122 R 
ATOM 954  C CG  . ARG A 1 122 ? -10.096 0.224   -10.996 1.0 94.34 ? 122 ARG A CG  1 Q8R3G1 UNP 122 R 
ATOM 955  C CD  . ARG A 1 122 ? -9.357  -0.926  -10.284 1.0 94.34 ? 122 ARG A CD  1 Q8R3G1 UNP 122 R 
ATOM 956  N NE  . ARG A 1 122 ? -9.714  -2.265  -10.807 1.0 94.34 ? 122 ARG A NE  1 Q8R3G1 UNP 122 R 
ATOM 957  N NH1 . ARG A 1 122 ? -8.068  -3.490  -9.726  1.0 94.34 ? 122 ARG A NH1 1 Q8R3G1 UNP 122 R 
ATOM 958  N NH2 . ARG A 1 122 ? -9.339  -4.490  -11.214 1.0 94.34 ? 122 ARG A NH2 1 Q8R3G1 UNP 122 R 
ATOM 959  C CZ  . ARG A 1 122 ? -9.052  -3.395  -10.572 1.0 94.34 ? 122 ARG A CZ  1 Q8R3G1 UNP 122 R 
ATOM 960  N N   . ALA A 1 123 ? -10.912 4.566   -9.464  1.0 95.08 ? 123 ALA A N   1 Q8R3G1 UNP 123 A 
ATOM 961  C CA  . ALA A 1 123 ? -10.764 5.670   -8.532  1.0 95.08 ? 123 ALA A CA  1 Q8R3G1 UNP 123 A 
ATOM 962  C C   . ALA A 1 123 ? -10.499 5.116   -7.125  1.0 95.08 ? 123 ALA A C   1 Q8R3G1 UNP 123 A 
ATOM 963  C CB  . ALA A 1 123 ? -12.060 6.485   -8.602  1.0 95.08 ? 123 ALA A CB  1 Q8R3G1 UNP 123 A 
ATOM 964  O O   . ALA A 1 123 ? -11.210 4.227   -6.671  1.0 95.08 ? 123 ALA A O   1 Q8R3G1 UNP 123 A 
ATOM 965  N N   . TYR A 1 124 ? -9.473  5.625   -6.450  1.0 96.57 ? 124 TYR A N   1 Q8R3G1 UNP 124 Y 
ATOM 966  C CA  . TYR A 1 124 ? -9.087  5.217   -5.100  1.0 96.57 ? 124 TYR A CA  1 Q8R3G1 UNP 124 Y 
ATOM 967  C C   . TYR A 1 124 ? -9.394  6.356   -4.136  1.0 96.57 ? 124 TYR A C   1 Q8R3G1 UNP 124 Y 
ATOM 968  C CB  . TYR A 1 124 ? -7.596  4.849   -5.058  1.0 96.57 ? 124 TYR A CB  1 Q8R3G1 UNP 124 Y 
ATOM 969  O O   . TYR A 1 124 ? -8.694  7.366   -4.147  1.0 96.57 ? 124 TYR A O   1 Q8R3G1 UNP 124 Y 
ATOM 970  C CG  . TYR A 1 124 ? -7.225  3.651   -5.905  1.0 96.57 ? 124 TYR A CG  1 Q8R3G1 UNP 124 Y 
ATOM 971  C CD1 . TYR A 1 124 ? -7.033  2.391   -5.307  1.0 96.57 ? 124 TYR A CD1 1 Q8R3G1 UNP 124 Y 
ATOM 972  C CD2 . TYR A 1 124 ? -7.082  3.797   -7.298  1.0 96.57 ? 124 TYR A CD2 1 Q8R3G1 UNP 124 Y 
ATOM 973  C CE1 . TYR A 1 124 ? -6.715  1.273   -6.102  1.0 96.57 ? 124 TYR A CE1 1 Q8R3G1 UNP 124 Y 
ATOM 974  C CE2 . TYR A 1 124 ? -6.778  2.683   -8.097  1.0 96.57 ? 124 TYR A CE2 1 Q8R3G1 UNP 124 Y 
ATOM 975  O OH  . TYR A 1 124 ? -6.279  0.351   -8.277  1.0 96.57 ? 124 TYR A OH  1 Q8R3G1 UNP 124 Y 
ATOM 976  C CZ  . TYR A 1 124 ? -6.587  1.420   -7.498  1.0 96.57 ? 124 TYR A CZ  1 Q8R3G1 UNP 124 Y 
ATOM 977  N N   . THR A 1 125 ? -10.429 6.219   -3.318  1.0 95.67 ? 125 THR A N   1 Q8R3G1 UNP 125 T 
ATOM 978  C CA  . THR A 1 125 ? -10.845 7.259   -2.372  1.0 95.67 ? 125 THR A CA  1 Q8R3G1 UNP 125 T 
ATOM 979  C C   . THR A 1 125 ? -10.343 6.925   -0.976  1.0 95.67 ? 125 THR A C   1 Q8R3G1 UNP 125 T 
ATOM 980  C CB  . THR A 1 125 ? -12.363 7.462   -2.399  1.0 95.67 ? 125 THR A CB  1 Q8R3G1 UNP 125 T 
ATOM 981  O O   . THR A 1 125 ? -10.627 5.853   -0.448  1.0 95.67 ? 125 THR A O   1 Q8R3G1 UNP 125 T 
ATOM 982  C CG2 . THR A 1 125 ? -12.798 8.668   -1.569  1.0 95.67 ? 125 THR A CG2 1 Q8R3G1 UNP 125 T 
ATOM 983  O OG1 . THR A 1 125 ? -12.793 7.679   -3.727  1.0 95.67 ? 125 THR A OG1 1 Q8R3G1 UNP 125 T 
ATOM 984  N N   . LEU A 1 126 ? -9.580  7.833   -0.371  1.0 94.75 ? 126 LEU A N   1 Q8R3G1 UNP 126 L 
ATOM 985  C CA  . LEU A 1 126 ? -9.081  7.660   0.993   1.0 94.75 ? 126 LEU A CA  1 Q8R3G1 UNP 126 L 
ATOM 986  C C   . LEU A 1 126 ? -10.193 7.911   2.004   1.0 94.75 ? 126 LEU A C   1 Q8R3G1 UNP 126 L 
ATOM 987  C CB  . LEU A 1 126 ? -7.875  8.593   1.195   1.0 94.75 ? 126 LEU A CB  1 Q8R3G1 UNP 126 L 
ATOM 988  O O   . LEU A 1 126 ? -10.686 9.028   2.077   1.0 94.75 ? 126 LEU A O   1 Q8R3G1 UNP 126 L 
ATOM 989  C CG  . LEU A 1 126 ? -7.277  8.549   2.612   1.0 94.75 ? 126 LEU A CG  1 Q8R3G1 UNP 126 L 
ATOM 990  C CD1 . LEU A 1 126 ? -6.724  7.171   2.974   1.0 94.75 ? 126 LEU A CD1 1 Q8R3G1 UNP 126 L 
ATOM 991  C CD2 . LEU A 1 126 ? -6.123  9.548   2.706   1.0 94.75 ? 126 LEU A CD2 1 Q8R3G1 UNP 126 L 
ATOM 992  N N   . ARG A 1 127 ? -10.542 6.910   2.813   1.0 92.02 ? 127 ARG A N   1 Q8R3G1 UNP 127 R 
ATOM 993  C CA  . ARG A 1 127 ? -11.558 7.030   3.862   1.0 92.02 ? 127 ARG A CA  1 Q8R3G1 UNP 127 R 
ATOM 994  C C   . ARG A 1 127 ? -11.030 6.555   5.211   1.0 92.02 ? 127 ARG A C   1 Q8R3G1 UNP 127 R 
ATOM 995  C CB  . ARG A 1 127 ? -12.844 6.290   3.460   1.0 92.02 ? 127 ARG A CB  1 Q8R3G1 UNP 127 R 
ATOM 996  O O   . ARG A 1 127 ? -10.075 5.781   5.314   1.0 92.02 ? 127 ARG A O   1 Q8R3G1 UNP 127 R 
ATOM 997  C CG  . ARG A 1 127 ? -13.463 6.826   2.158   1.0 92.02 ? 127 ARG A CG  1 Q8R3G1 UNP 127 R 
ATOM 998  C CD  . ARG A 1 127 ? -14.922 6.375   2.043   1.0 92.02 ? 127 ARG A CD  1 Q8R3G1 UNP 127 R 
ATOM 999  N NE  . ARG A 1 127 ? -15.373 6.335   0.642   1.0 92.02 ? 127 ARG A NE  1 Q8R3G1 UNP 127 R 
ATOM 1000 N NH1 . ARG A 1 127 ? -17.549 7.009   0.956   1.0 92.02 ? 127 ARG A NH1 1 Q8R3G1 UNP 127 R 
ATOM 1001 N NH2 . ARG A 1 127 ? -16.883 6.294   -1.049  1.0 92.02 ? 127 ARG A NH2 1 Q8R3G1 UNP 127 R 
ATOM 1002 C CZ  . ARG A 1 127 ? -16.594 6.555   0.195   1.0 92.02 ? 127 ARG A CZ  1 Q8R3G1 UNP 127 R 
ATOM 1003 N N   . GLU A 1 128 ? -11.662 7.044   6.265   1.0 89.25 ? 128 GLU A N   1 Q8R3G1 UNP 128 E 
ATOM 1004 C CA  . GLU A 1 128 ? -11.479 6.549   7.625   1.0 89.25 ? 128 GLU A CA  1 Q8R3G1 UNP 128 E 
ATOM 1005 C C   . GLU A 1 128 ? -12.711 5.734   8.017   1.0 89.25 ? 128 GLU A C   1 Q8R3G1 UNP 128 E 
ATOM 1006 C CB  . GLU A 1 128 ? -11.184 7.726   8.569   1.0 89.25 ? 128 GLU A CB  1 Q8R3G1 UNP 128 E 
ATOM 1007 O O   . GLU A 1 128 ? -13.812 5.977   7.521   1.0 89.25 ? 128 GLU A O   1 Q8R3G1 UNP 128 E 
ATOM 1008 C CG  . GLU A 1 128 ? -10.715 7.266   9.960   1.0 89.25 ? 128 GLU A CG  1 Q8R3G1 UNP 128 E 
ATOM 1009 C CD  . GLU A 1 128 ? -10.223 8.412   10.867  1.0 89.25 ? 128 GLU A CD  1 Q8R3G1 UNP 128 E 
ATOM 1010 O OE1 . GLU A 1 128 ? -9.843  8.107   12.024  1.0 89.25 ? 128 GLU A OE1 1 Q8R3G1 UNP 128 E 
ATOM 1011 O OE2 . GLU A 1 128 ? -10.157 9.574   10.406  1.0 89.25 ? 128 GLU A OE2 1 Q8R3G1 UNP 128 E 
ATOM 1012 N N   . LYS A 1 129 ? -12.533 4.721   8.870   1.0 80.82 ? 129 LYS A N   1 Q8R3G1 UNP 129 K 
ATOM 1013 C CA  . LYS A 1 129 ? -13.651 3.954   9.413   1.0 80.82 ? 129 LYS A CA  1 Q8R3G1 UNP 129 K 
ATOM 1014 C C   . LYS A 1 129 ? -14.624 4.941   10.068  1.0 80.82 ? 129 LYS A C   1 Q8R3G1 UNP 129 K 
ATOM 1015 C CB  . LYS A 1 129 ? -13.136 2.904   10.410  1.0 80.82 ? 129 LYS A CB  1 Q8R3G1 UNP 129 K 
ATOM 1016 O O   . LYS A 1 129 ? -14.163 5.721   10.906  1.0 80.82 ? 129 LYS A O   1 Q8R3G1 UNP 129 K 
ATOM 1017 C CG  . LYS A 1 129 ? -14.281 2.055   10.978  1.0 80.82 ? 129 LYS A CG  1 Q8R3G1 UNP 129 K 
ATOM 1018 C CD  . LYS A 1 129 ? -13.768 0.959   11.914  1.0 80.82 ? 129 LYS A CD  1 Q8R3G1 UNP 129 K 
ATOM 1019 C CE  . LYS A 1 129 ? -14.977 0.191   12.457  1.0 80.82 ? 129 LYS A CE  1 Q8R3G1 UNP 129 K 
ATOM 1020 N NZ  . LYS A 1 129 ? -14.572 -0.987  13.260  1.0 80.82 ? 129 LYS A NZ  1 Q8R3G1 UNP 129 K 
ATOM 1021 N N   . PRO A 1 130 ? -15.928 4.896   9.742   1.0 67.36 ? 130 PRO A N   1 Q8R3G1 UNP 130 P 
ATOM 1022 C CA  . PRO A 1 130 ? -16.908 5.679   10.473  1.0 67.36 ? 130 PRO A CA  1 Q8R3G1 UNP 130 P 
ATOM 1023 C C   . PRO A 1 130 ? -16.770 5.306   11.948  1.0 67.36 ? 130 PRO A C   1 Q8R3G1 UNP 130 P 
ATOM 1024 C CB  . PRO A 1 130 ? -18.275 5.346   9.860   1.0 67.36 ? 130 PRO A CB  1 Q8R3G1 UNP 130 P 
ATOM 1025 O O   . PRO A 1 130 ? -16.938 4.144   12.337  1.0 67.36 ? 130 PRO A O   1 Q8R3G1 UNP 130 P 
ATOM 1026 C CG  . PRO A 1 130 ? -18.058 4.011   9.149   1.0 67.36 ? 130 PRO A CG  1 Q8R3G1 UNP 130 P 
ATOM 1027 C CD  . PRO A 1 130 ? -16.581 4.037   8.764   1.0 67.36 ? 130 PRO A CD  1 Q8R3G1 UNP 130 P 
ATOM 1028 N N   . GLN A 1 131 ? -16.321 6.266   12.760  1.0 61.14 ? 131 GLN A N   1 Q8R3G1 UNP 131 Q 
ATOM 1029 C CA  . GLN A 1 131 ? -16.286 6.075   14.196  1.0 61.14 ? 131 GLN A CA  1 Q8R3G1 UNP 131 Q 
ATOM 1030 C C   . GLN A 1 131 ? -17.740 5.944   14.613  1.0 61.14 ? 131 GLN A C   1 Q8R3G1 UNP 131 Q 
ATOM 1031 C CB  . GLN A 1 131 ? -15.585 7.237   14.925  1.0 61.14 ? 131 GLN A CB  1 Q8R3G1 UNP 131 Q 
ATOM 1032 O O   . GLN A 1 131 ? -18.481 6.921   14.581  1.0 61.14 ? 131 GLN A O   1 Q8R3G1 UNP 131 Q 
ATOM 1033 C CG  . GLN A 1 131 ? -14.060 7.205   14.741  1.0 61.14 ? 131 GLN A CG  1 Q8R3G1 UNP 131 Q 
ATOM 1034 C CD  . GLN A 1 131 ? -13.318 8.254   15.571  1.0 61.14 ? 131 GLN A CD  1 Q8R3G1 UNP 131 Q 
ATOM 1035 N NE2 . GLN A 1 131 ? -12.015 8.345   15.428  1.0 61.14 ? 131 GLN A NE2 1 Q8R3G1 UNP 131 Q 
ATOM 1036 O OE1 . GLN A 1 131 ? -13.862 9.003   16.366  1.0 61.14 ? 131 GLN A OE1 1 Q8R3G1 UNP 131 Q 
ATOM 1037 N N   . THR A 1 132 ? -18.139 4.736   15.002  1.0 52.44 ? 132 THR A N   1 Q8R3G1 UNP 132 T 
ATOM 1038 C CA  . THR A 1 132 ? -19.335 4.520   15.808  1.0 52.44 ? 132 THR A CA  1 Q8R3G1 UNP 132 T 
ATOM 1039 C C   . THR A 1 132 ? -19.071 5.230   17.133  1.0 52.44 ? 132 THR A C   1 Q8R3G1 UNP 132 T 
ATOM 1040 C CB  . THR A 1 132 ? -19.612 3.017   16.004  1.0 52.44 ? 132 THR A CB  1 Q8R3G1 UNP 132 T 
ATOM 1041 O O   . THR A 1 132 ? -18.568 4.635   18.089  1.0 52.44 ? 132 THR A O   1 Q8R3G1 UNP 132 T 
ATOM 1042 C CG2 . THR A 1 132 ? -19.906 2.299   14.688  1.0 52.44 ? 132 THR A CG2 1 Q8R3G1 UNP 132 T 
ATOM 1043 O OG1 . THR A 1 132 ? -18.481 2.391   16.583  1.0 52.44 ? 132 THR A OG1 1 Q8R3G1 UNP 132 T 
ATOM 1044 N N   . LEU A 1 133 ? -19.258 6.548   17.163  1.0 51.81 ? 133 LEU A N   1 Q8R3G1 UNP 133 L 
ATOM 1045 C CA  . LEU A 1 133 ? -19.293 7.287   18.407  1.0 51.81 ? 133 LEU A CA  1 Q8R3G1 UNP 133 L 
ATOM 1046 C C   . LEU A 1 133 ? -20.441 6.664   19.203  1.0 51.81 ? 133 LEU A C   1 Q8R3G1 UNP 133 L 
ATOM 1047 C CB  . LEU A 1 133 ? -19.535 8.784   18.133  1.0 51.81 ? 133 LEU A CB  1 Q8R3G1 UNP 133 L 
ATOM 1048 O O   . LEU A 1 133 ? -21.550 6.569   18.678  1.0 51.81 ? 133 LEU A O   1 Q8R3G1 UNP 133 L 
ATOM 1049 C CG  . LEU A 1 133 ? -18.300 9.529   17.591  1.0 51.81 ? 133 LEU A CG  1 Q8R3G1 UNP 133 L 
ATOM 1050 C CD1 . LEU A 1 133 ? -18.711 10.874  16.995  1.0 51.81 ? 133 LEU A CD1 1 Q8R3G1 UNP 133 L 
ATOM 1051 C CD2 . LEU A 1 133 ? -17.274 9.801   18.698  1.0 51.81 ? 133 LEU A CD2 1 Q8R3G1 UNP 133 L 
ATOM 1052 N N   . PRO A 1 134 ? -20.226 6.218   20.450  1.0 44.95 ? 134 PRO A N   1 Q8R3G1 UNP 134 P 
ATOM 1053 C CA  . PRO A 1 134 ? -21.355 6.077   21.341  1.0 44.95 ? 134 PRO A CA  1 Q8R3G1 UNP 134 P 
ATOM 1054 C C   . PRO A 1 134 ? -21.886 7.500   21.512  1.0 44.95 ? 134 PRO A C   1 Q8R3G1 UNP 134 P 
ATOM 1055 C CB  . PRO A 1 134 ? -20.793 5.442   22.615  1.0 44.95 ? 134 PRO A CB  1 Q8R3G1 UNP 134 P 
ATOM 1056 O O   . PRO A 1 134 ? -21.256 8.308   22.197  1.0 44.95 ? 134 PRO A O   1 Q8R3G1 UNP 134 P 
ATOM 1057 C CG  . PRO A 1 134 ? -19.321 5.863   22.629  1.0 44.95 ? 134 PRO A CG  1 Q8R3G1 UNP 134 P 
ATOM 1058 C CD  . PRO A 1 134 ? -18.964 6.078   21.157  1.0 44.95 ? 134 PRO A CD  1 Q8R3G1 UNP 134 P 
ATOM 1059 N N   . SER A 1 135 ? -22.981 7.833   20.825  1.0 43.99 ? 135 SER A N   1 Q8R3G1 UNP 135 S 
ATOM 1060 C CA  . SER A 1 135 ? -23.728 9.078   21.002  1.0 43.99 ? 135 SER A CA  1 Q8R3G1 UNP 135 S 
ATOM 1061 C C   . SER A 1 135 ? -24.299 9.106   22.416  1.0 43.99 ? 135 SER A C   1 Q8R3G1 UNP 135 S 
ATOM 1062 C CB  . SER A 1 135 ? -24.817 9.233   19.932  1.0 43.99 ? 135 SER A CB  1 Q8R3G1 UNP 135 S 
ATOM 1063 O O   . SER A 1 135 ? -25.473 8.874   22.669  1.0 43.99 ? 135 SER A O   1 Q8R3G1 UNP 135 S 
ATOM 1064 O OG  . SER A 1 135 ? -24.201 9.596   18.713  1.0 43.99 ? 135 SER A OG  1 Q8R3G1 UNP 135 S 
ATOM 1065 N N   . ALA A 1 136 ? -23.422 9.368   23.374  1.0 43.46 ? 136 ALA A N   1 Q8R3G1 UNP 136 A 
ATOM 1066 C CA  . ALA A 1 136 ? -23.748 9.764   24.714  1.0 43.46 ? 136 ALA A CA  1 Q8R3G1 UNP 136 A 
ATOM 1067 C C   . ALA A 1 136 ? -23.489 11.273  24.782  1.0 43.46 ? 136 ALA A C   1 Q8R3G1 UNP 136 A 
ATOM 1068 C CB  . ALA A 1 136 ? -22.925 8.920   25.700  1.0 43.46 ? 136 ALA A CB  1 Q8R3G1 UNP 136 A 
ATOM 1069 O O   . ALA A 1 136 ? -22.343 11.719  24.796  1.0 43.46 ? 136 ALA A O   1 Q8R3G1 UNP 136 A 
ATOM 1070 N N   . VAL A 1 137 ? -24.583 12.031  24.922  1.0 49.86 ? 137 VAL A N   1 Q8R3G1 UNP 137 V 
ATOM 1071 C CA  . VAL A 1 137 ? -24.628 13.364  25.549  1.0 49.86 ? 137 VAL A CA  1 Q8R3G1 UNP 137 V 
ATOM 1072 C C   . VAL A 1 137 ? -24.332 14.567  24.626  1.0 49.86 ? 137 VAL A C   1 Q8R3G1 UNP 137 V 
ATOM 1073 C CB  . VAL A 1 137 ? -23.793 13.360  26.869  1.0 49.86 ? 137 VAL A CB  1 Q8R3G1 UNP 137 V 
ATOM 1074 O O   . VAL A 1 137 ? -23.244 15.133  24.685  1.0 49.86 ? 137 VAL A O   1 Q8R3G1 UNP 137 V 
ATOM 1075 C CG1 . VAL A 1 137 ? -23.990 14.614  27.723  1.0 49.86 ? 137 VAL A CG1 1 Q8R3G1 UNP 137 V 
ATOM 1076 C CG2 . VAL A 1 137 ? -24.144 12.182  27.796  1.0 49.86 ? 137 VAL A CG2 1 Q8R3G1 UNP 137 V 
ATOM 1077 N N   . LYS A 1 138 ? -25.355 15.047  23.884  1.0 49.71 ? 138 LYS A N   1 Q8R3G1 UNP 138 K 
ATOM 1078 C CA  . LYS A 1 138 ? -25.962 16.412  23.989  1.0 49.71 ? 138 LYS A CA  1 Q8R3G1 UNP 138 K 
ATOM 1079 C C   . LYS A 1 138 ? -26.697 16.879  22.713  1.0 49.71 ? 138 LYS A C   1 Q8R3G1 UNP 138 K 
ATOM 1080 C CB  . LYS A 1 138 ? -24.948 17.516  24.377  1.0 49.71 ? 138 LYS A CB  1 Q8R3G1 UNP 138 K 
ATOM 1081 O O   . LYS A 1 138 ? -26.054 17.336  21.781  1.0 49.71 ? 138 LYS A O   1 Q8R3G1 UNP 138 K 
ATOM 1082 C CG  . LYS A 1 138 ? -24.852 17.651  25.901  1.0 49.71 ? 138 LYS A CG  1 Q8R3G1 UNP 138 K 
ATOM 1083 C CD  . LYS A 1 138 ? -23.547 18.320  26.335  1.0 49.71 ? 138 LYS A CD  1 Q8R3G1 UNP 138 K 
ATOM 1084 C CE  . LYS A 1 138 ? -23.505 18.401  27.863  1.0 49.71 ? 138 LYS A CE  1 Q8R3G1 UNP 138 K 
ATOM 1085 N NZ  . LYS A 1 138 ? -22.296 19.119  28.320  1.0 49.71 ? 138 LYS A NZ  1 Q8R3G1 UNP 138 K 
ATOM 1086 N N   . GLY A 1 139 ? -28.033 16.834  22.785  1.0 44.35 ? 139 GLY A N   1 Q8R3G1 UNP 139 G 
ATOM 1087 C CA  . GLY A 1 139 ? -29.017 17.866  22.401  1.0 44.35 ? 139 GLY A CA  1 Q8R3G1 UNP 139 G 
ATOM 1088 C C   . GLY A 1 139 ? -28.945 18.558  21.035  1.0 44.35 ? 139 GLY A C   1 Q8R3G1 UNP 139 G 
ATOM 1089 O O   . GLY A 1 139 ? -28.042 19.351  20.808  1.0 44.35 ? 139 GLY A O   1 Q8R3G1 UNP 139 G 
ATOM 1090 N N   . ASP A 1 140 ? -29.998 18.401  20.229  1.0 50.40 ? 140 ASP A N   1 Q8R3G1 UNP 140 D 
ATOM 1091 C CA  . ASP A 1 140 ? -30.994 19.465  20.001  1.0 50.40 ? 140 ASP A CA  1 Q8R3G1 UNP 140 D 
ATOM 1092 C C   . ASP A 1 140 ? -32.273 18.864  19.386  1.0 50.40 ? 140 ASP A C   1 Q8R3G1 UNP 140 D 
ATOM 1093 C CB  . ASP A 1 140 ? -30.462 20.615  19.127  1.0 50.40 ? 140 ASP A CB  1 Q8R3G1 UNP 140 D 
ATOM 1094 O O   . ASP A 1 140 ? -32.224 17.919  18.604  1.0 50.40 ? 140 ASP A O   1 Q8R3G1 UNP 140 D 
ATOM 1095 C CG  . ASP A 1 140 ? -31.276 21.902  19.317  1.0 50.40 ? 140 ASP A CG  1 Q8R3G1 UNP 140 D 
ATOM 1096 O OD1 . ASP A 1 140 ? -31.712 22.479  18.295  1.0 50.40 ? 140 ASP A OD1 1 Q8R3G1 UNP 140 D 
ATOM 1097 O OD2 . ASP A 1 140 ? -31.406 22.333  20.486  1.0 50.40 ? 140 ASP A OD2 1 Q8R3G1 UNP 140 D 
ATOM 1098 N N   . GLU A 1 141 ? -33.420 19.378  19.813  1.0 44.52 ? 141 GLU A N   1 Q8R3G1 UNP 141 E 
ATOM 1099 C CA  . GLU A 1 141 ? -34.765 18.847  19.595  1.0 44.52 ? 141 GLU A CA  1 Q8R3G1 UNP 141 E 
ATOM 1100 C C   . GLU A 1 141 ? -35.259 19.091  18.156  1.0 44.52 ? 141 GLU A C   1 Q8R3G1 UNP 141 E 
ATOM 1101 C CB  . GLU A 1 141 ? -35.703 19.559  20.597  1.0 44.52 ? 141 GLU A CB  1 Q8R3G1 UNP 141 E 
ATOM 1102 O O   . GLU A 1 141 ? -35.391 20.241  17.731  1.0 44.52 ? 141 GLU A O   1 Q8R3G1 UNP 141 E 
ATOM 1103 C CG  . GLU A 1 141 ? -35.335 19.348  22.079  1.0 44.52 ? 141 GLU A CG  1 Q8R3G1 UNP 141 E 
ATOM 1104 C CD  . GLU A 1 141 ? -36.092 20.316  23.004  1.0 44.52 ? 141 GLU A CD  1 Q8R3G1 UNP 141 E 
ATOM 1105 O OE1 . GLU A 1 141 ? -37.058 19.871  23.663  1.0 44.52 ? 141 GLU A OE1 1 Q8R3G1 UNP 141 E 
ATOM 1106 O OE2 . GLU A 1 141 ? -35.683 21.498  23.081  1.0 44.52 ? 141 GLU A OE2 1 Q8R3G1 UNP 141 E 
ATOM 1107 N N   . LYS A 1 142 ? -35.639 18.042  17.408  1.0 50.81 ? 142 LYS A N   1 Q8R3G1 UNP 142 K 
ATOM 1108 C CA  . LYS A 1 142 ? -36.580 18.202  16.285  1.0 50.81 ? 142 LYS A CA  1 Q8R3G1 UNP 142 K 
ATOM 1109 C C   . LYS A 1 142 ? -37.296 16.905  15.907  1.0 50.81 ? 142 LYS A C   1 Q8R3G1 UNP 142 K 
ATOM 1110 C CB  . LYS A 1 142 ? -35.889 18.847  15.066  1.0 50.81 ? 142 LYS A CB  1 Q8R3G1 UNP 142 K 
ATOM 1111 O O   . LYS A 1 142 ? -36.680 15.946  15.472  1.0 50.81 ? 142 LYS A O   1 Q8R3G1 UNP 142 K 
ATOM 1112 C CG  . LYS A 1 142 ? -36.633 20.133  14.673  1.0 50.81 ? 142 LYS A CG  1 Q8R3G1 UNP 142 K 
ATOM 1113 C CD  . LYS A 1 142 ? -35.893 20.862  13.556  1.0 50.81 ? 142 LYS A CD  1 Q8R3G1 UNP 142 K 
ATOM 1114 C CE  . LYS A 1 142 ? -36.601 22.181  13.251  1.0 50.81 ? 142 LYS A CE  1 Q8R3G1 UNP 142 K 
ATOM 1115 N NZ  . LYS A 1 142 ? -35.862 22.926  12.207  1.0 50.81 ? 142 LYS A NZ  1 Q8R3G1 UNP 142 K 
ATOM 1116 N N   . MET A 1 143 ? -38.619 16.956  16.065  1.0 42.42 ? 143 MET A N   1 Q8R3G1 UNP 143 M 
ATOM 1117 C CA  . MET A 1 143 ? -39.631 15.949  15.736  1.0 42.42 ? 143 MET A CA  1 Q8R3G1 UNP 143 M 
ATOM 1118 C C   . MET A 1 143 ? -39.331 15.072  14.507  1.0 42.42 ? 143 MET A C   1 Q8R3G1 UNP 143 M 
ATOM 1119 C CB  . MET A 1 143 ? -40.953 16.687  15.446  1.0 42.42 ? 143 MET A CB  1 Q8R3G1 UNP 143 M 
ATOM 1120 O O   . MET A 1 143 ? -39.327 15.576  13.384  1.0 42.42 ? 143 MET A O   1 Q8R3G1 UNP 143 M 
ATOM 1121 C CG  . MET A 1 143 ? -41.618 17.313  16.674  1.0 42.42 ? 143 MET A CG  1 Q8R3G1 UNP 143 M 
ATOM 1122 S SD  . MET A 1 143 ? -43.433 17.287  16.596  1.0 42.42 ? 143 MET A SD  1 Q8R3G1 UNP 143 M 
ATOM 1123 C CE  . MET A 1 143 ? -43.785 18.562  15.364  1.0 42.42 ? 143 MET A CE  1 Q8R3G1 UNP 143 M 
ATOM 1124 N N   . GLY A 1 144 ? -39.239 13.757  14.718  1.0 46.58 ? 144 GLY A N   1 Q8R3G1 UNP 144 G 
ATOM 1125 C CA  . GLY A 1 144 ? -39.338 12.736  13.674  1.0 46.58 ? 144 GLY A CA  1 Q8R3G1 UNP 144 G 
ATOM 1126 C C   . GLY A 1 144 ? -39.326 11.324  14.272  1.0 46.58 ? 144 GLY A C   1 Q8R3G1 UNP 144 G 
ATOM 1127 O O   . GLY A 1 144 ? -38.352 10.981  14.917  1.0 46.58 ? 144 GLY A O   1 Q8R3G1 UNP 144 G 
ATOM 1128 N N   . GLY A 1 145 ? -40.416 10.566  14.081  1.0 50.35 ? 145 GLY A N   1 Q8R3G1 UNP 145 G 
ATOM 1129 C CA  . GLY A 1 145 ? -40.513 9.095   14.190  1.0 50.35 ? 145 GLY A CA  1 Q8R3G1 UNP 145 G 
ATOM 1130 C C   . GLY A 1 145 ? -39.978 8.413   15.459  1.0 50.35 ? 145 GLY A C   1 Q8R3G1 UNP 145 G 
ATOM 1131 O O   . GLY A 1 145 ? -38.778 8.220   15.615  1.0 50.35 ? 145 GLY A O   1 Q8R3G1 UNP 145 G 
ATOM 1132 N N   . GLU A 1 146 ? -40.876 7.929   16.322  1.0 59.06 ? 146 GLU A N   1 Q8R3G1 UNP 146 E 
ATOM 1133 C CA  . GLU A 1 146 ? -40.565 7.118   17.522  1.0 59.06 ? 146 GLU A CA  1 Q8R3G1 UNP 146 E 
ATOM 1134 C C   . GLU A 1 146 ? -39.757 5.834   17.199  1.0 59.06 ? 146 GLU A C   1 Q8R3G1 UNP 146 E 
ATOM 1135 C CB  . GLU A 1 146 ? -41.898 6.729   18.202  1.0 59.06 ? 146 GLU A CB  1 Q8R3G1 UNP 146 E 
ATOM 1136 O O   . GLU A 1 146 ? -39.130 5.227   18.067  1.0 59.06 ? 146 GLU A O   1 Q8R3G1 UNP 146 E 
ATOM 1137 C CG  . GLU A 1 146 ? -42.831 7.925   18.498  1.0 59.06 ? 146 GLU A CG  1 Q8R3G1 UNP 146 E 
ATOM 1138 C CD  . GLU A 1 146 ? -44.199 7.530   19.087  1.0 59.06 ? 146 GLU A CD  1 Q8R3G1 UNP 146 E 
ATOM 1139 O OE1 . GLU A 1 146 ? -44.793 8.382   19.789  1.0 59.06 ? 146 GLU A OE1 1 Q8R3G1 UNP 146 E 
ATOM 1140 O OE2 . GLU A 1 146 ? -44.686 6.411   18.803  1.0 59.06 ? 146 GLU A OE2 1 Q8R3G1 UNP 146 E 
ATOM 1141 N N   . ASP A 1 147 ? -39.765 5.424   15.933  1.0 61.83 ? 147 ASP A N   1 Q8R3G1 UNP 147 D 
ATOM 1142 C CA  . ASP A 1 147 ? -39.072 4.282   15.354  1.0 61.83 ? 147 ASP A CA  1 Q8R3G1 UNP 147 D 
ATOM 1143 C C   . ASP A 1 147 ? -37.609 4.558   14.949  1.0 61.83 ? 147 ASP A C   1 Q8R3G1 UNP 147 D 
ATOM 1144 C CB  . ASP A 1 147 ? -39.927 3.723   14.195  1.0 61.83 ? 147 ASP A CB  1 Q8R3G1 UNP 147 D 
ATOM 1145 O O   . ASP A 1 147 ? -36.792 3.631   14.989  1.0 61.83 ? 147 ASP A O   1 Q8R3G1 UNP 147 D 
ATOM 1146 C CG  . ASP A 1 147 ? -40.508 4.729   13.173  1.0 61.83 ? 147 ASP A CG  1 Q8R3G1 UNP 147 D 
ATOM 1147 O OD1 . ASP A 1 147 ? -40.975 5.825   13.576  1.0 61.83 ? 147 ASP A OD1 1 Q8R3G1 UNP 147 D 
ATOM 1148 O OD2 . ASP A 1 147 ? -40.606 4.323   11.994  1.0 61.83 ? 147 ASP A OD2 1 Q8R3G1 UNP 147 D 
ATOM 1149 N N   . ASP A 1 148 ? -37.243 5.806   14.642  1.0 59.51 ? 148 ASP A N   1 Q8R3G1 UNP 148 D 
ATOM 1150 C CA  . ASP A 1 148 ? -35.859 6.187   14.320  1.0 59.51 ? 148 ASP A CA  1 Q8R3G1 UNP 148 D 
ATOM 1151 C C   . ASP A 1 148 ? -35.026 6.449   15.589  1.0 59.51 ? 148 ASP A C   1 Q8R3G1 UNP 148 D 
ATOM 1152 C CB  . ASP A 1 148 ? -35.850 7.389   13.357  1.0 59.51 ? 148 ASP A CB  1 Q8R3G1 UNP 148 D 
ATOM 1153 O O   . ASP A 1 148 ? -33.843 6.100   15.653  1.0 59.51 ? 148 ASP A O   1 Q8R3G1 UNP 148 D 
ATOM 1154 C CG  . ASP A 1 148 ? -36.165 6.991   11.905  1.0 59.51 ? 148 ASP A CG  1 Q8R3G1 UNP 148 D 
ATOM 1155 O OD1 . ASP A 1 148 ? -35.654 5.931   11.459  1.0 59.51 ? 148 ASP A OD1 1 Q8R3G1 UNP 148 D 
ATOM 1156 O OD2 . ASP A 1 148 ? -36.885 7.765   11.232  1.0 59.51 ? 148 ASP A OD2 1 Q8R3G1 UNP 148 D 
ATOM 1157 N N   . GLU A 1 149 ? -35.658 6.947   16.657  1.0 56.76 ? 149 GLU A N   1 Q8R3G1 UNP 149 E 
ATOM 1158 C CA  . GLU A 1 149 ? -34.988 7.244   17.932  1.0 56.76 ? 149 GLU A CA  1 Q8R3G1 UNP 149 E 
ATOM 1159 C C   . GLU A 1 149 ? -34.466 5.971   18.633  1.0 56.76 ? 149 GLU A C   1 Q8R3G1 UNP 149 E 
ATOM 1160 C CB  . GLU A 1 149 ? -35.945 8.066   18.822  1.0 56.76 ? 149 GLU A CB  1 Q8R3G1 UNP 149 E 
ATOM 1161 O O   . GLU A 1 149 ? -33.414 5.986   19.277  1.0 56.76 ? 149 GLU A O   1 Q8R3G1 UNP 149 E 
ATOM 1162 C CG  . GLU A 1 149 ? -35.188 9.030   19.748  1.0 56.76 ? 149 GLU A CG  1 Q8R3G1 UNP 149 E 
ATOM 1163 C CD  . GLU A 1 149 ? -36.123 9.945   20.562  1.0 56.76 ? 149 GLU A CD  1 Q8R3G1 UNP 149 E 
ATOM 1164 O OE1 . GLU A 1 149 ? -35.982 9.953   21.809  1.0 56.76 ? 149 GLU A OE1 1 Q8R3G1 UNP 149 E 
ATOM 1165 O OE2 . GLU A 1 149 ? -36.941 10.668  19.951  1.0 56.76 ? 149 GLU A OE2 1 Q8R3G1 UNP 149 E 
ATOM 1166 N N   . LEU A 1 150 ? -35.133 4.824   18.443  1.0 58.63 ? 150 LEU A N   1 Q8R3G1 UNP 150 L 
ATOM 1167 C CA  . LEU A 1 150 ? -34.686 3.541   19.001  1.0 58.63 ? 150 LEU A CA  1 Q8R3G1 UNP 150 L 
ATOM 1168 C C   . LEU A 1 150 ? -33.457 2.970   18.268  1.0 58.63 ? 150 LEU A C   1 Q8R3G1 UNP 150 L 
ATOM 1169 C CB  . LEU A 1 150 ? -35.856 2.540   18.980  1.0 58.63 ? 150 LEU A CB  1 Q8R3G1 UNP 150 L 
ATOM 1170 O O   . LEU A 1 150 ? -32.653 2.261   18.877  1.0 58.63 ? 150 LEU A O   1 Q8R3G1 UNP 150 L 
ATOM 1171 C CG  . LEU A 1 150 ? -35.675 1.398   20.003  1.0 58.63 ? 150 LEU A CG  1 Q8R3G1 UNP 150 L 
ATOM 1172 C CD1 . LEU A 1 150 ? -36.220 1.795   21.378  1.0 58.63 ? 150 LEU A CD1 1 Q8R3G1 UNP 150 L 
ATOM 1173 C CD2 . LEU A 1 150 ? -36.402 0.133   19.548  1.0 58.63 ? 150 LEU A CD2 1 Q8R3G1 UNP 150 L 
ATOM 1174 N N   . LYS A 1 151 ? -33.290 3.263   16.970  1.0 58.85 ? 151 LYS A N   1 Q8R3G1 UNP 151 K 
ATOM 1175 C CA  . LYS A 1 151 ? -32.159 2.765   16.168  1.0 58.85 ? 151 LYS A CA  1 Q8R3G1 UNP 151 K 
ATOM 1176 C C   . LYS A 1 151 ? -30.857 3.486   16.511  1.0 58.85 ? 151 LYS A C   1 Q8R3G1 UNP 151 K 
ATOM 1177 C CB  . LYS A 1 151 ? -32.468 2.889   14.674  1.0 58.85 ? 151 LYS A CB  1 Q8R3G1 UNP 151 K 
ATOM 1178 O O   . LYS A 1 151 ? -29.852 2.811   16.748  1.0 58.85 ? 151 LYS A O   1 Q8R3G1 UNP 151 K 
ATOM 1179 C CG  . LYS A 1 151 ? -33.473 1.836   14.191  1.0 58.85 ? 151 LYS A CG  1 Q8R3G1 UNP 151 K 
ATOM 1180 C CD  . LYS A 1 151 ? -33.706 2.072   12.700  1.0 58.85 ? 151 LYS A CD  1 Q8R3G1 UNP 151 K 
ATOM 1181 C CE  . LYS A 1 151 ? -34.624 1.027   12.075  1.0 58.85 ? 151 LYS A CE  1 Q8R3G1 UNP 151 K 
ATOM 1182 N NZ  . LYS A 1 151 ? -34.833 1.382   10.654  1.0 58.85 ? 151 LYS A NZ  1 Q8R3G1 UNP 151 K 
ATOM 1183 N N   . GLY A 1 152 ? -30.900 4.814   16.645  1.0 59.30 ? 152 GLY A N   1 Q8R3G1 UNP 152 G 
ATOM 1184 C CA  . GLY A 1 152 ? -29.751 5.612   17.093  1.0 59.30 ? 152 GLY A CA  1 Q8R3G1 UNP 152 G 
ATOM 1185 C C   . GLY A 1 152 ? -29.309 5.266   18.523  1.0 59.30 ? 152 GLY A C   1 Q8R3G1 UNP 152 G 
ATOM 1186 O O   . GLY A 1 152 ? -28.115 5.223   18.829  1.0 59.30 ? 152 GLY A O   1 Q8R3G1 UNP 152 G 
ATOM 1187 N N   . LEU A 1 153 ? -30.254 4.896   19.401  1.0 58.61 ? 153 LEU A N   1 Q8R3G1 UNP 153 L 
ATOM 1188 C CA  . LEU A 1 153 ? -29.966 4.487   20.784  1.0 58.61 ? 153 LEU A CA  1 Q8R3G1 UNP 153 L 
ATOM 1189 C C   . LEU A 1 153 ? -29.189 3.165   20.904  1.0 58.61 ? 153 LEU A C   1 Q8R3G1 UNP 153 L 
ATOM 1190 C CB  . LEU A 1 153 ? -31.289 4.411   21.577  1.0 58.61 ? 153 LEU A CB  1 Q8R3G1 UNP 153 L 
ATOM 1191 O O   . LEU A 1 153 ? -28.531 2.930   21.920  1.0 58.61 ? 153 LEU A O   1 Q8R3G1 UNP 153 L 
ATOM 1192 C CG  . LEU A 1 153 ? -31.381 5.452   22.714  1.0 58.61 ? 153 LEU A CG  1 Q8R3G1 UNP 153 L 
ATOM 1193 C CD1 . LEU A 1 153 ? -32.624 6.325   22.572  1.0 58.61 ? 153 LEU A CD1 1 Q8R3G1 UNP 153 L 
ATOM 1194 C CD2 . LEU A 1 153 ? -31.430 4.760   24.080  1.0 58.61 ? 153 LEU A CD2 1 Q8R3G1 UNP 153 L 
ATOM 1195 N N   . LEU A 1 154 ? -29.246 2.303   19.886  1.0 59.19 ? 154 LEU A N   1 Q8R3G1 UNP 154 L 
ATOM 1196 C CA  . LEU A 1 154 ? -28.577 0.999   19.884  1.0 59.19 ? 154 LEU A CA  1 Q8R3G1 UNP 154 L 
ATOM 1197 C C   . LEU A 1 154 ? -27.176 1.028   19.252  1.0 59.19 ? 154 LEU A C   1 Q8R3G1 UNP 154 L 
ATOM 1198 C CB  . LEU A 1 154 ? -29.512 -0.050  19.253  1.0 59.19 ? 154 LEU A CB  1 Q8R3G1 UNP 154 L 
ATOM 1199 O O   . LEU A 1 154 ? -26.536 -0.021  19.162  1.0 59.19 ? 154 LEU A O   1 Q8R3G1 UNP 154 L 
ATOM 1200 C CG  . LEU A 1 154 ? -30.762 -0.361  20.101  1.0 59.19 ? 154 LEU A CG  1 Q8R3G1 UNP 154 L 
ATOM 1201 C CD1 . LEU A 1 154 ? -31.663 -1.334  19.339  1.0 59.19 ? 154 LEU A CD1 1 Q8R3G1 UNP 154 L 
ATOM 1202 C CD2 . LEU A 1 154 ? -30.416 -1.004  21.450  1.0 59.19 ? 154 LEU A CD2 1 Q8R3G1 UNP 154 L 
ATOM 1203 N N   . GLY A 1 155 ? -26.677 2.201   18.839  1.0 61.51 ? 155 GLY A N   1 Q8R3G1 UNP 155 G 
ATOM 1204 C CA  . GLY A 1 155 ? -25.362 2.331   18.199  1.0 61.51 ? 155 GLY A CA  1 Q8R3G1 UNP 155 G 
ATOM 1205 C C   . GLY A 1 155 ? -25.246 1.535   16.894  1.0 61.51 ? 155 GLY A C   1 Q8R3G1 UNP 155 G 
ATOM 1206 O O   . GLY A 1 155 ? -24.147 1.138   16.500  1.0 61.51 ? 155 GLY A O   1 Q8R3G1 UNP 155 G 
ATOM 1207 N N   . LEU A 1 156 ? -26.387 1.249   16.265  1.0 64.95 ? 156 LEU A N   1 Q8R3G1 UNP 156 L 
ATOM 1208 C CA  . LEU A 1 156 ? -26.468 0.621   14.956  1.0 64.95 ? 156 LEU A CA  1 Q8R3G1 UNP 156 L 
ATOM 1209 C C   . LEU A 1 156 ? -26.320 1.717   13.889  1.0 64.95 ? 156 LEU A C   1 Q8R3G1 UNP 156 L 
ATOM 1210 C CB  . LEU A 1 156 ? -27.804 -0.135  14.837  1.0 64.95 ? 156 LEU A CB  1 Q8R3G1 UNP 156 L 
ATOM 1211 O O   . LEU A 1 156 ? -26.835 2.810   14.109  1.0 64.95 ? 156 LEU A O   1 Q8R3G1 UNP 156 L 
ATOM 1212 C CG  . LEU A 1 156 ? -27.918 -1.352  15.775  1.0 64.95 ? 156 LEU A CG  1 Q8R3G1 UNP 156 L 
ATOM 1213 C CD1 . LEU A 1 156 ? -29.349 -1.892  15.768  1.0 64.95 ? 156 LEU A CD1 1 Q8R3G1 UNP 156 L 
ATOM 1214 C CD2 . LEU A 1 156 ? -26.982 -2.491  15.355  1.0 64.95 ? 156 LEU A CD2 1 Q8R3G1 UNP 156 L 
ATOM 1215 N N   . PRO A 1 157 ? -25.629 1.453   12.763  1.0 64.07 ? 157 PRO A N   1 Q8R3G1 UNP 157 P 
ATOM 1216 C CA  . PRO A 1 157 ? -25.541 2.406   11.655  1.0 64.07 ? 157 PRO A CA  1 Q8R3G1 UNP 157 P 
ATOM 1217 C C   . PRO A 1 157 ? -26.934 2.912   11.258  1.0 64.07 ? 157 PRO A C   1 Q8R3G1 UNP 157 P 
ATOM 1218 C CB  . PRO A 1 157 ? -24.859 1.641   10.516  1.0 64.07 ? 157 PRO A CB  1 Q8R3G1 UNP 157 P 
ATOM 1219 O O   . PRO A 1 157 ? -27.836 2.098   11.040  1.0 64.07 ? 157 PRO A O   1 Q8R3G1 UNP 157 P 
ATOM 1220 C CG  . PRO A 1 157 ? -24.048 0.569   11.240  1.0 64.07 ? 157 PRO A CG  1 Q8R3G1 UNP 157 P 
ATOM 1221 C CD  . PRO A 1 157 ? -24.918 0.227   12.444  1.0 64.07 ? 157 PRO A CD  1 Q8R3G1 UNP 157 P 
ATOM 1222 N N   . GLU A 1 158 ? -27.112 4.234   11.224  1.0 66.85 ? 158 GLU A N   1 Q8R3G1 UNP 158 E 
ATOM 1223 C CA  . GLU A 1 158 ? -28.421 4.873   11.012  1.0 66.85 ? 158 GLU A CA  1 Q8R3G1 UNP 158 E 
ATOM 1224 C C   . GLU A 1 158 ? -28.808 4.868   9.525   1.0 66.85 ? 158 GLU A C   1 Q8R3G1 UNP 158 E 
ATOM 1225 C CB  . GLU A 1 158 ? -28.412 6.307   11.586  1.0 66.85 ? 158 GLU A CB  1 Q8R3G1 UNP 158 E 
ATOM 1226 O O   . GLU A 1 158 ? -29.981 4.728   9.179   1.0 66.85 ? 158 GLU A O   1 Q8R3G1 UNP 158 E 
ATOM 1227 C CG  . GLU A 1 158 ? -28.315 6.330   13.126  1.0 66.85 ? 158 GLU A CG  1 Q8R3G1 UNP 158 E 
ATOM 1228 C CD  . GLU A 1 158 ? -28.291 7.741   13.751  1.0 66.85 ? 158 GLU A CD  1 Q8R3G1 UNP 158 E 
ATOM 1229 O OE1 . GLU A 1 158 ? -28.232 7.805   15.004  1.0 66.85 ? 158 GLU A OE1 1 Q8R3G1 UNP 158 E 
ATOM 1230 O OE2 . GLU A 1 158 ? -28.310 8.746   13.005  1.0 66.85 ? 158 GLU A OE2 1 Q8R3G1 UNP 158 E 
ATOM 1231 N N   . GLU A 1 159 ? -27.812 4.944   8.638   1.0 75.37 ? 159 GLU A N   1 Q8R3G1 UNP 159 E 
ATOM 1232 C CA  . GLU A 1 159 ? -27.988 4.968   7.186   1.0 75.37 ? 159 GLU A CA  1 Q8R3G1 UNP 159 E 
ATOM 1233 C C   . GLU A 1 159 ? -27.607 3.618   6.545   1.0 75.37 ? 159 GLU A C   1 Q8R3G1 UNP 159 E 
ATOM 1234 C CB  . GLU A 1 159 ? -27.162 6.134   6.613   1.0 75.37 ? 159 GLU A CB  1 Q8R3G1 UNP 159 E 
ATOM 1235 O O   . GLU A 1 159 ? -26.594 3.009   6.900   1.0 75.37 ? 159 GLU A O   1 Q8R3G1 UNP 159 E 
ATOM 1236 C CG  . GLU A 1 159 ? -27.611 6.551   5.206   1.0 75.37 ? 159 GLU A CG  1 Q8R3G1 UNP 159 E 
ATOM 1237 C CD  . GLU A 1 159 ? -26.685 7.589   4.545   1.0 75.37 ? 159 GLU A CD  1 Q8R3G1 UNP 159 E 
ATOM 1238 O OE1 . GLU A 1 159 ? -26.691 7.629   3.290   1.0 75.37 ? 159 GLU A OE1 1 Q8R3G1 UNP 159 E 
ATOM 1239 O OE2 . GLU A 1 159 ? -25.929 8.289   5.248   1.0 75.37 ? 159 GLU A OE2 1 Q8R3G1 UNP 159 E 
ATOM 1240 N N   . GLU A 1 160 ? -28.369 3.170   5.538   1.0 79.83 ? 160 GLU A N   1 Q8R3G1 UNP 160 E 
ATOM 1241 C CA  . GLU A 1 160 ? -28.036 1.991   4.712   1.0 79.83 ? 160 GLU A CA  1 Q8R3G1 UNP 160 E 
ATOM 1242 C C   . GLU A 1 160 ? -26.610 2.100   4.138   1.0 79.83 ? 160 GLU A C   1 Q8R3G1 UNP 160 E 
ATOM 1243 C CB  . GLU A 1 160 ? -29.097 1.856   3.602   1.0 79.83 ? 160 GLU A CB  1 Q8R3G1 UNP 160 E 
ATOM 1244 O O   . GLU A 1 160 ? -25.824 1.156   4.219   1.0 79.83 ? 160 GLU A O   1 Q8R3G1 UNP 160 E 
ATOM 1245 C CG  . GLU A 1 160 ? -28.954 0.596   2.726   1.0 79.83 ? 160 GLU A CG  1 Q8R3G1 UNP 160 E 
ATOM 1246 C CD  . GLU A 1 160 ? -30.093 0.433   1.694   1.0 79.83 ? 160 GLU A CD  1 Q8R3G1 UNP 160 E 
ATOM 1247 O OE1 . GLU A 1 160 ? -30.125 -0.615  1.007   1.0 79.83 ? 160 GLU A OE1 1 Q8R3G1 UNP 160 E 
ATOM 1248 O OE2 . GLU A 1 160 ? -30.968 1.328   1.612   1.0 79.83 ? 160 GLU A OE2 1 Q8R3G1 UNP 160 E 
ATOM 1249 N N   . THR A 1 161 ? -26.224 3.302   3.697   1.0 81.41 ? 161 THR A N   1 Q8R3G1 UNP 161 T 
ATOM 1250 C CA  . THR A 1 161 ? -24.875 3.621   3.212   1.0 81.41 ? 161 THR A CA  1 Q8R3G1 UNP 161 T 
ATOM 1251 C C   . THR A 1 161 ? -23.788 3.372   4.265   1.0 81.41 ? 161 THR A C   1 Q8R3G1 UNP 161 T 
ATOM 1252 C CB  . THR A 1 161 ? -24.806 5.101   2.795   1.0 81.41 ? 161 THR A CB  1 Q8R3G1 UNP 161 T 
ATOM 1253 O O   . THR A 1 161 ? -22.700 2.888   3.942   1.0 81.41 ? 161 THR A O   1 Q8R3G1 UNP 161 T 
ATOM 1254 C CG2 . THR A 1 161 ? -23.535 5.430   2.013   1.0 81.41 ? 161 THR A CG2 1 Q8R3G1 UNP 161 T 
ATOM 1255 O OG1 . THR A 1 161 ? -25.891 5.466   1.976   1.0 81.41 ? 161 THR A OG1 1 Q8R3G1 UNP 161 T 
ATOM 1256 N N   . GLU A 1 162 ? -24.027 3.706   5.535   1.0 80.68 ? 162 GLU A N   1 Q8R3G1 UNP 162 E 
ATOM 1257 C CA  . GLU A 1 162 ? -23.058 3.467   6.611   1.0 80.68 ? 162 GLU A CA  1 Q8R3G1 UNP 162 E 
ATOM 1258 C C   . GLU A 1 162 ? -22.927 1.976   6.924   1.0 80.68 ? 162 GLU A C   1 Q8R3G1 UNP 162 E 
ATOM 1259 C CB  . GLU A 1 162 ? -23.464 4.196   7.893   1.0 80.68 ? 162 GLU A CB  1 Q8R3G1 UNP 162 E 
ATOM 1260 O O   . GLU A 1 162 ? -21.812 1.478   7.125   1.0 80.68 ? 162 GLU A O   1 Q8R3G1 UNP 162 E 
ATOM 1261 C CG  . GLU A 1 162 ? -23.309 5.718   7.817   1.0 80.68 ? 162 GLU A CG  1 Q8R3G1 UNP 162 E 
ATOM 1262 C CD  . GLU A 1 162 ? -23.604 6.381   9.173   1.0 80.68 ? 162 GLU A CD  1 Q8R3G1 UNP 162 E 
ATOM 1263 O OE1 . GLU A 1 162 ? -23.230 7.566   9.308   1.0 80.68 ? 162 GLU A OE1 1 Q8R3G1 UNP 162 E 
ATOM 1264 O OE2 . GLU A 1 162 ? -24.089 5.673   10.091  1.0 80.68 ? 162 GLU A OE2 1 Q8R3G1 UNP 162 E 
ATOM 1265 N N   . LEU A 1 163 ? -24.056 1.260   6.932   1.0 80.25 ? 163 LEU A N   1 Q8R3G1 UNP 163 L 
ATOM 1266 C CA  . LEU A 1 163 ? -24.094 -0.181  7.152   1.0 80.25 ? 163 LEU A CA  1 Q8R3G1 UNP 163 L 
ATOM 1267 C C   . LEU A 1 163 ? -23.330 -0.934  6.057   1.0 80.25 ? 163 LEU A C   1 Q8R3G1 UNP 163 L 
ATOM 1268 C CB  . LEU A 1 163 ? -25.561 -0.637  7.231   1.0 80.25 ? 163 LEU A CB  1 Q8R3G1 UNP 163 L 
ATOM 1269 O O   . LEU A 1 163 ? -22.541 -1.831  6.374   1.0 80.25 ? 163 LEU A O   1 Q8R3G1 UNP 163 L 
ATOM 1270 C CG  . LEU A 1 163 ? -25.730 -2.127  7.573   1.0 80.25 ? 163 LEU A CG  1 Q8R3G1 UNP 163 L 
ATOM 1271 C CD1 . LEU A 1 163 ? -25.152 -2.479  8.950   1.0 80.25 ? 163 LEU A CD1 1 Q8R3G1 UNP 163 L 
ATOM 1272 C CD2 . LEU A 1 163 ? -27.213 -2.490  7.578   1.0 80.25 ? 163 LEU A CD2 1 Q8R3G1 UNP 163 L 
ATOM 1273 N N   . ASP A 1 164 ? -23.504 -0.541  4.797   1.0 84.26 ? 164 ASP A N   1 Q8R3G1 UNP 164 D 
ATOM 1274 C CA  . ASP A 1 164 ? -22.782 -1.109  3.659   1.0 84.26 ? 164 ASP A CA  1 Q8R3G1 UNP 164 D 
ATOM 1275 C C   . ASP A 1 164 ? -21.281 -0.845  3.771   1.0 84.26 ? 164 ASP A C   1 Q8R3G1 UNP 164 D 
ATOM 1276 C CB  . ASP A 1 164 ? -23.341 -0.536  2.348   1.0 84.26 ? 164 ASP A CB  1 Q8R3G1 UNP 164 D 
ATOM 1277 O O   . ASP A 1 164 ? -20.478 -1.782  3.742   1.0 84.26 ? 164 ASP A O   1 Q8R3G1 UNP 164 D 
ATOM 1278 C CG  . ASP A 1 164 ? -24.651 -1.196  1.905   1.0 84.26 ? 164 ASP A CG  1 Q8R3G1 UNP 164 D 
ATOM 1279 O OD1 . ASP A 1 164 ? -25.024 -2.233  2.507   1.0 84.26 ? 164 ASP A OD1 1 Q8R3G1 UNP 164 D 
ATOM 1280 O OD2 . ASP A 1 164 ? -25.200 -0.709  0.894   1.0 84.26 ? 164 ASP A OD2 1 Q8R3G1 UNP 164 D 
ATOM 1281 N N   . ASN A 1 165 ? -20.887 0.404   4.034   1.0 84.08 ? 165 ASN A N   1 Q8R3G1 UNP 165 N 
ATOM 1282 C CA  . ASN A 1 165 ? -19.482 0.762   4.222   1.0 84.08 ? 165 ASN A CA  1 Q8R3G1 UNP 165 N 
ATOM 1283 C C   . ASN A 1 165 ? -18.824 -0.030  5.364   1.0 84.08 ? 165 ASN A C   1 Q8R3G1 UNP 165 N 
ATOM 1284 C CB  . ASN A 1 165 ? -19.380 2.271   4.492   1.0 84.08 ? 165 ASN A CB  1 Q8R3G1 UNP 165 N 
ATOM 1285 O O   . ASN A 1 165 ? -17.685 -0.490  5.227   1.0 84.08 ? 165 ASN A O   1 Q8R3G1 UNP 165 N 
ATOM 1286 C CG  . ASN A 1 165 ? -19.462 3.088   3.221   1.0 84.08 ? 165 ASN A CG  1 Q8R3G1 UNP 165 N 
ATOM 1287 N ND2 . ASN A 1 165 ? -20.302 4.087   3.177   1.0 84.08 ? 165 ASN A ND2 1 Q8R3G1 UNP 165 N 
ATOM 1288 O OD1 . ASN A 1 165 ? -18.711 2.877   2.281   1.0 84.08 ? 165 ASN A OD1 1 Q8R3G1 UNP 165 N 
ATOM 1289 N N   . LEU A 1 166 ? -19.528 -0.211  6.488   1.0 82.92 ? 166 LEU A N   1 Q8R3G1 UNP 166 L 
ATOM 1290 C CA  . LEU A 1 166 ? -19.051 -0.994  7.627   1.0 82.92 ? 166 LEU A CA  1 Q8R3G1 UNP 166 L 
ATOM 1291 C C   . LEU A 1 166 ? -18.946 -2.486  7.285   1.0 82.92 ? 166 LEU A C   1 Q8R3G1 UNP 166 L 
ATOM 1292 C CB  . LEU A 1 166 ? -19.995 -0.754  8.820   1.0 82.92 ? 166 LEU A CB  1 Q8R3G1 UNP 166 L 
ATOM 1293 O O   . LEU A 1 166 ? -17.961 -3.139  7.646   1.0 82.92 ? 166 LEU A O   1 Q8R3G1 UNP 166 L 
ATOM 1294 C CG  . LEU A 1 166 ? -19.597 -1.505  10.103  1.0 82.92 ? 166 LEU A CG  1 Q8R3G1 UNP 166 L 
ATOM 1295 C CD1 . LEU A 1 166 ? -18.213 -1.089  10.620  1.0 82.92 ? 166 LEU A CD1 1 Q8R3G1 UNP 166 L 
ATOM 1296 C CD2 . LEU A 1 166 ? -20.619 -1.244  11.206  1.0 82.92 ? 166 LEU A CD2 1 Q8R3G1 UNP 166 L 
ATOM 1297 N N   . THR A 1 167 ? -19.940 -3.025  6.582   1.0 85.17 ? 167 THR A N   1 Q8R3G1 UNP 167 T 
ATOM 1298 C CA  . THR A 1 167 ? -19.973 -4.424  6.140   1.0 85.17 ? 167 THR A CA  1 Q8R3G1 UNP 167 T 
ATOM 1299 C C   . THR A 1 167 ? -18.819 -4.719  5.193   1.0 85.17 ? 167 THR A C   1 Q8R3G1 UNP 167 T 
ATOM 1300 C CB  . THR A 1 167 ? -21.314 -4.746  5.465   1.0 85.17 ? 167 THR A CB  1 Q8R3G1 UNP 167 T 
ATOM 1301 O O   . THR A 1 167 ? -18.085 -5.692  5.384   1.0 85.17 ? 167 THR A O   1 Q8R3G1 UNP 167 T 
ATOM 1302 C CG2 . THR A 1 167 ? -21.389 -6.193  4.973   1.0 85.17 ? 167 THR A CG2 1 Q8R3G1 UNP 167 T 
ATOM 1303 O OG1 . THR A 1 167 ? -22.329 -4.590  6.425   1.0 85.17 ? 167 THR A OG1 1 Q8R3G1 UNP 167 T 
ATOM 1304 N N   . GLU A 1 168 ? -18.594 -3.856  4.210   1.0 85.46 ? 168 GLU A N   1 Q8R3G1 UNP 168 E 
ATOM 1305 C CA  . GLU A 1 168 ? -17.497 -3.965  3.256   1.0 85.46 ? 168 GLU A CA  1 Q8R3G1 UNP 168 E 
ATOM 1306 C C   . GLU A 1 168 ? -16.133 -3.803  3.934   1.0 85.46 ? 168 GLU A C   1 Q8R3G1 UNP 168 E 
ATOM 1307 C CB  . GLU A 1 168 ? -17.673 -2.887  2.198   1.0 85.46 ? 168 GLU A CB  1 Q8R3G1 UNP 168 E 
ATOM 1308 O O   . GLU A 1 168 ? -15.215 -4.569  3.641   1.0 85.46 ? 168 GLU A O   1 Q8R3G1 UNP 168 E 
ATOM 1309 C CG  . GLU A 1 168 ? -18.855 -3.151  1.255   1.0 85.46 ? 168 GLU A CG  1 Q8R3G1 UNP 168 E 
ATOM 1310 C CD  . GLU A 1 168 ? -19.094 -1.954  0.330   1.0 85.46 ? 168 GLU A CD  1 Q8R3G1 UNP 168 E 
ATOM 1311 O OE1 . GLU A 1 168 ? -19.600 -2.188  -0.790  1.0 85.46 ? 168 GLU A OE1 1 Q8R3G1 UNP 168 E 
ATOM 1312 O OE2 . GLU A 1 168 ? -18.639 -0.844  0.694   1.0 85.46 ? 168 GLU A OE2 1 Q8R3G1 UNP 168 E 
ATOM 1313 N N   . PHE A 1 169 ? -15.997 -2.872  4.887   1.0 82.91 ? 169 PHE A N   1 Q8R3G1 UNP 169 F 
ATOM 1314 C CA  . PHE A 1 169 ? -14.767 -2.697  5.667   1.0 82.91 ? 169 PHE A CA  1 Q8R3G1 UNP 169 F 
ATOM 1315 C C   . PHE A 1 169 ? -14.434 -3.964  6.463   1.0 82.91 ? 169 PHE A C   1 Q8R3G1 UNP 169 F 
ATOM 1316 C CB  . PHE A 1 169 ? -14.904 -1.479  6.595   1.0 82.91 ? 169 PHE A CB  1 Q8R3G1 UNP 169 F 
ATOM 1317 O O   . PHE A 1 169 ? -13.319 -4.483  6.382   1.0 82.91 ? 169 PHE A O   1 Q8R3G1 UNP 169 F 
ATOM 1318 C CG  . PHE A 1 169 ? -13.706 -1.273  7.506   1.0 82.91 ? 169 PHE A CG  1 Q8R3G1 UNP 169 F 
ATOM 1319 C CD1 . PHE A 1 169 ? -13.642 -1.921  8.755   1.0 82.91 ? 169 PHE A CD1 1 Q8R3G1 UNP 169 F 
ATOM 1320 C CD2 . PHE A 1 169 ? -12.629 -0.475  7.081   1.0 82.91 ? 169 PHE A CD2 1 Q8R3G1 UNP 169 F 
ATOM 1321 C CE1 . PHE A 1 169 ? -12.491 -1.805  9.555   1.0 82.91 ? 169 PHE A CE1 1 Q8R3G1 UNP 169 F 
ATOM 1322 C CE2 . PHE A 1 169 ? -11.490 -0.333  7.894   1.0 82.91 ? 169 PHE A CE2 1 Q8R3G1 UNP 169 F 
ATOM 1323 C CZ  . PHE A 1 169 ? -11.413 -1.012  9.123   1.0 82.91 ? 169 PHE A CZ  1 Q8R3G1 UNP 169 F 
ATOM 1324 N N   . ASN A 1 170 ? -15.413 -4.507  7.193   1.0 85.50 ? 170 ASN A N   1 Q8R3G1 UNP 170 N 
ATOM 1325 C CA  . ASN A 1 170 ? -15.240 -5.735  7.968   1.0 85.50 ? 170 ASN A CA  1 Q8R3G1 UNP 170 N 
ATOM 1326 C C   . ASN A 1 170 ? -14.952 -6.940  7.055   1.0 85.50 ? 170 ASN A C   1 Q8R3G1 UNP 170 N 
ATOM 1327 C CB  . ASN A 1 170 ? -16.498 -5.962  8.822   1.0 85.50 ? 170 ASN A CB  1 Q8R3G1 UNP 170 N 
ATOM 1328 O O   . ASN A 1 170 ? -14.115 -7.784  7.379   1.0 85.50 ? 170 ASN A O   1 Q8R3G1 UNP 170 N 
ATOM 1329 C CG  . ASN A 1 170 ? -16.648 -4.978  9.974   1.0 85.50 ? 170 ASN A CG  1 Q8R3G1 UNP 170 N 
ATOM 1330 N ND2 . ASN A 1 170 ? -17.862 -4.755  10.417  1.0 85.50 ? 170 ASN A ND2 1 Q8R3G1 UNP 170 N 
ATOM 1331 O OD1 . ASN A 1 170 ? -15.694 -4.438  10.520  1.0 85.50 ? 170 ASN A OD1 1 Q8R3G1 UNP 170 N 
ATOM 1332 N N   . THR A 1 171 ? -15.597 -7.004  5.887   1.0 87.03 ? 171 THR A N   1 Q8R3G1 UNP 171 T 
ATOM 1333 C CA  . THR A 1 171 ? -15.360 -8.043  4.874   1.0 87.03 ? 171 THR A CA  1 Q8R3G1 UNP 171 T 
ATOM 1334 C C   . THR A 1 171 ? -13.936 -7.973  4.327   1.0 87.03 ? 171 THR A C   1 Q8R3G1 UNP 171 T 
ATOM 1335 C CB  . THR A 1 171 ? -16.378 -7.934  3.728   1.0 87.03 ? 171 THR A CB  1 Q8R3G1 UNP 171 T 
ATOM 1336 O O   . THR A 1 171 ? -13.244 -8.992  4.285   1.0 87.03 ? 171 THR A O   1 Q8R3G1 UNP 171 T 
ATOM 1337 C CG2 . THR A 1 171 ? -16.168 -8.995  2.647   1.0 87.03 ? 171 THR A CG2 1 Q8R3G1 UNP 171 T 
ATOM 1338 O OG1 . THR A 1 171 ? -17.667 -8.143  4.246   1.0 87.03 ? 171 THR A OG1 1 Q8R3G1 UNP 171 T 
ATOM 1339 N N   . ALA A 1 172 ? -13.461 -6.783  3.956   1.0 81.28 ? 172 ALA A N   1 Q8R3G1 UNP 172 A 
ATOM 1340 C CA  . ALA A 1 172 ? -12.101 -6.566  3.471   1.0 81.28 ? 172 ALA A CA  1 Q8R3G1 UNP 172 A 
ATOM 1341 C C   . ALA A 1 172 ? -11.048 -6.905  4.534   1.0 81.28 ? 172 ALA A C   1 Q8R3G1 UNP 172 A 
ATOM 1342 C CB  . ALA A 1 172 ? -11.980 -5.109  3.029   1.0 81.28 ? 172 ALA A CB  1 Q8R3G1 UNP 172 A 
ATOM 1343 O O   . ALA A 1 172 ? -10.079 -7.615  4.247   1.0 81.28 ? 172 ALA A O   1 Q8R3G1 UNP 172 A 
ATOM 1344 N N   . HIS A 1 173 ? -11.274 -6.469  5.775   1.0 80.76 ? 173 HIS A N   1 Q8R3G1 UNP 173 H 
ATOM 1345 C CA  . HIS A 1 173 ? -10.418 -6.796  6.911   1.0 80.76 ? 173 HIS A CA  1 Q8R3G1 UNP 173 H 
ATOM 1346 C C   . HIS A 1 173 ? -10.305 -8.319  7.110   1.0 80.76 ? 173 HIS A C   1 Q8R3G1 UNP 173 H 
ATOM 1347 C CB  . HIS A 1 173 ? -10.973 -6.077  8.148   1.0 80.76 ? 173 HIS A CB  1 Q8R3G1 UNP 173 H 
ATOM 1348 O O   . HIS A 1 173 ? -9.204  -8.854  7.232   1.0 80.76 ? 173 HIS A O   1 Q8R3G1 UNP 173 H 
ATOM 1349 C CG  . HIS A 1 173 ? -10.106 -6.246  9.364   1.0 80.76 ? 173 HIS A CG  1 Q8R3G1 UNP 173 H 
ATOM 1350 C CD2 . HIS A 1 173 ? -9.140  -5.382  9.808   1.0 80.76 ? 173 HIS A CD2 1 Q8R3G1 UNP 173 H 
ATOM 1351 N ND1 . HIS A 1 173 ? -10.129 -7.317  10.229  1.0 80.76 ? 173 HIS A ND1 1 Q8R3G1 UNP 173 H 
ATOM 1352 C CE1 . HIS A 1 173 ? -9.193  -7.105  11.168  1.0 80.76 ? 173 HIS A CE1 1 Q8R3G1 UNP 173 H 
ATOM 1353 N NE2 . HIS A 1 173 ? -8.573  -5.936  10.960  1.0 80.76 ? 173 HIS A NE2 1 Q8R3G1 UNP 173 H 
ATOM 1354 N N   . ASN A 1 174 ? -11.421 -9.052  7.045   1.0 77.38 ? 174 ASN A N   1 Q8R3G1 UNP 174 N 
ATOM 1355 C CA  . ASN A 1 174 ? -11.427 -10.513 7.179   1.0 77.38 ? 174 ASN A CA  1 Q8R3G1 UNP 174 N 
ATOM 1356 C C   . ASN A 1 174 ? -10.810 -11.246 5.971   1.0 77.38 ? 174 ASN A C   1 Q8R3G1 UNP 174 N 
ATOM 1357 C CB  . ASN A 1 174 ? -12.870 -10.971 7.442   1.0 77.38 ? 174 ASN A CB  1 Q8R3G1 UNP 174 N 
ATOM 1358 O O   . ASN A 1 174 ? -10.125 -12.259 6.147   1.0 77.38 ? 174 ASN A O   1 Q8R3G1 UNP 174 N 
ATOM 1359 C CG  . ASN A 1 174 ? -13.378 -10.568 8.817   1.0 77.38 ? 174 ASN A CG  1 Q8R3G1 UNP 174 N 
ATOM 1360 N ND2 . ASN A 1 174 ? -14.676 -10.491 8.991   1.0 77.38 ? 174 ASN A ND2 1 Q8R3G1 UNP 174 N 
ATOM 1361 O OD1 . ASN A 1 174 ? -12.627 -10.350 9.755   1.0 77.38 ? 174 ASN A OD1 1 Q8R3G1 UNP 174 N 
ATOM 1362 N N   . LYS A 1 175 ? -10.999 -10.737 4.744   1.0 79.72 ? 175 LYS A N   1 Q8R3G1 UNP 175 K 
ATOM 1363 C CA  . LYS A 1 175 ? -10.386 -11.296 3.523   1.0 79.72 ? 175 LYS A CA  1 Q8R3G1 UNP 175 K 
ATOM 1364 C C   . LYS A 1 175 ? -8.858  -11.271 3.610   1.0 79.72 ? 175 LYS A C   1 Q8R3G1 UNP 175 K 
ATOM 1365 C CB  . LYS A 1 175 ? -10.904 -10.526 2.294   1.0 79.72 ? 175 LYS A CB  1 Q8R3G1 UNP 175 K 
ATOM 1366 O O   . LYS A 1 175 ? -8.212  -12.250 3.243   1.0 79.72 ? 175 LYS A O   1 Q8R3G1 UNP 175 K 
ATOM 1367 C CG  . LYS A 1 175 ? -10.452 -11.137 0.955   1.0 79.72 ? 175 LYS A CG  1 Q8R3G1 UNP 175 K 
ATOM 1368 C CD  . LYS A 1 175 ? -10.988 -10.306 -0.222  1.0 79.72 ? 175 LYS A CD  1 Q8R3G1 UNP 175 K 
ATOM 1369 C CE  . LYS A 1 175 ? -10.500 -10.847 -1.574  1.0 79.72 ? 175 LYS A CE  1 Q8R3G1 UNP 175 K 
ATOM 1370 N NZ  . LYS A 1 175 ? -10.860 -9.930  -2.691  1.0 79.72 ? 175 LYS A NZ  1 Q8R3G1 UNP 175 K 
ATOM 1371 N N   . ARG A 1 176 ? -8.292  -10.199 4.172   1.0 67.44 ? 176 ARG A N   1 Q8R3G1 UNP 176 R 
ATOM 1372 C CA  . ARG A 1 176 ? -6.847  -10.045 4.394   1.0 67.44 ? 176 ARG A CA  1 Q8R3G1 UNP 176 R 
ATOM 1373 C C   . ARG A 1 176 ? -6.267  -11.087 5.355   1.0 67.44 ? 176 ARG A C   1 Q8R3G1 UNP 176 R 
ATOM 1374 C CB  . ARG A 1 176 ? -6.607  -8.624  4.912   1.0 67.44 ? 176 ARG A CB  1 Q8R3G1 UNP 176 R 
ATOM 1375 O O   . ARG A 1 176 ? -5.154  -11.560 5.146   1.0 67.44 ? 176 ARG A O   1 Q8R3G1 UNP 176 R 
ATOM 1376 C CG  . ARG A 1 176 ? -5.123  -8.259  4.893   1.0 67.44 ? 176 ARG A CG  1 Q8R3G1 UNP 176 R 
ATOM 1377 C CD  . ARG A 1 176 ? -4.957  -6.844  5.439   1.0 67.44 ? 176 ARG A CD  1 Q8R3G1 UNP 176 R 
ATOM 1378 N NE  . ARG A 1 176 ? -3.582  -6.378  5.242   1.0 67.44 ? 176 ARG A NE  1 Q8R3G1 UNP 176 R 
ATOM 1379 N NH1 . ARG A 1 176 ? -3.817  -4.414  6.412   1.0 67.44 ? 176 ARG A NH1 1 Q8R3G1 UNP 176 R 
ATOM 1380 N NH2 . ARG A 1 176 ? -1.823  -5.016  5.600   1.0 67.44 ? 176 ARG A NH2 1 Q8R3G1 UNP 176 R 
ATOM 1381 C CZ  . ARG A 1 176 ? -3.093  -5.259  5.734   1.0 67.44 ? 176 ARG A CZ  1 Q8R3G1 UNP 176 R 
ATOM 1382 N N   . ILE A 1 177 ? -7.029  -11.486 6.377   1.0 58.75 ? 177 ILE A N   1 Q8R3G1 UNP 177 I 
ATOM 1383 C CA  . ILE A 1 177 ? -6.610  -12.534 7.324   1.0 58.75 ? 177 ILE A CA  1 Q8R3G1 UNP 177 I 
ATOM 1384 C C   . ILE A 1 177 ? -6.523  -13.894 6.616   1.0 58.75 ? 177 ILE A C   1 Q8R3G1 UNP 177 I 
ATOM 1385 C CB  . ILE A 1 177 ? -7.555  -12.572 8.550   1.0 58.75 ? 177 ILE A CB  1 Q8R3G1 UNP 177 I 
ATOM 1386 O O   . ILE A 1 177 ? -5.636  -14.689 6.911   1.0 58.75 ? 177 ILE A O   1 Q8R3G1 UNP 177 I 
ATOM 1387 C CG1 . ILE A 1 177 ? -7.527  -11.219 9.300   1.0 58.75 ? 177 ILE A CG1 1 Q8R3G1 UNP 177 I 
ATOM 1388 C CG2 . ILE A 1 177 ? -7.167  -13.711 9.514   1.0 58.75 ? 177 ILE A CG2 1 Q8R3G1 UNP 177 I 
ATOM 1389 C CD1 . ILE A 1 177 ? -8.598  -11.079 10.390  1.0 58.75 ? 177 ILE A CD1 1 Q8R3G1 UNP 177 I 
ATOM 1390 N N   . SER A 1 178 ? -7.397  -14.151 5.639   1.0 55.00 ? 178 SER A N   1 Q8R3G1 UNP 178 S 
ATOM 1391 C CA  . SER A 1 178 ? -7.427  -15.431 4.916   1.0 55.00 ? 178 SER A CA  1 Q8R3G1 UNP 178 S 
ATOM 1392 C C   . SER A 1 178 ? -6.290  -15.593 3.893   1.0 55.00 ? 178 SER A C   1 Q8R3G1 UNP 178 S 
ATOM 1393 C CB  . SER A 1 178 ? -8.785  -15.625 4.239   1.0 55.00 ? 178 SER A CB  1 Q8R3G1 UNP 178 S 
ATOM 1394 O O   . SER A 1 178 ? -5.959  -16.720 3.540   1.0 55.00 ? 178 SER A O   1 Q8R3G1 UNP 178 S 
ATOM 1395 O OG  . SER A 1 178 ? -9.826  -15.611 5.201   1.0 55.00 ? 178 SER A OG  1 Q8R3G1 UNP 178 S 
ATOM 1396 N N   . THR A 1 179 ? -5.669  -14.498 3.431   1.0 52.88 ? 179 THR A N   1 Q8R3G1 UNP 179 T 
ATOM 1397 C CA  . THR A 1 179 ? -4.509  -14.532 2.515   1.0 52.88 ? 179 THR A CA  1 Q8R3G1 UNP 179 T 
ATOM 1398 C C   . THR A 1 179 ? -3.165  -14.722 3.217   1.0 52.88 ? 179 THR A C   1 Q8R3G1 UNP 179 T 
ATOM 1399 C CB  . THR A 1 179 ? -4.440  -13.287 1.619   1.0 52.88 ? 179 THR A CB  1 Q8R3G1 UNP 179 T 
ATOM 1400 O O   . THR A 1 179 ? -2.156  -14.892 2.539   1.0 52.88 ? 179 THR A O   1 Q8R3G1 UNP 179 T 
ATOM 1401 C CG2 . THR A 1 179 ? -5.604  -13.247 0.630   1.0 52.88 ? 179 THR A CG2 1 Q8R3G1 UNP 179 T 
ATOM 1402 O OG1 . THR A 1 179 ? -4.519  -12.101 2.376   1.0 52.88 ? 179 THR A OG1 1 Q8R3G1 UNP 179 T 
ATOM 1403 N N   . LEU A 1 180 ? -3.128  -14.740 4.556   1.0 50.30 ? 180 LEU A N   1 Q8R3G1 UNP 180 L 
ATOM 1404 C CA  . LEU A 1 180 ? -2.019  -15.354 5.288   1.0 50.30 ? 180 LEU A CA  1 Q8R3G1 UNP 180 L 
ATOM 1405 C C   . LEU A 1 180 ? -2.159  -16.871 5.141   1.0 50.30 ? 180 LEU A C   1 Q8R3G1 UNP 180 L 
ATOM 1406 C CB  . LEU A 1 180 ? -1.990  -14.876 6.751   1.0 50.30 ? 180 LEU A CB  1 Q8R3G1 UNP 180 L 
ATOM 1407 O O   . LEU A 1 180 ? -2.628  -17.581 6.030   1.0 50.30 ? 180 LEU A O   1 Q8R3G1 UNP 180 L 
ATOM 1408 C CG  . LEU A 1 180 ? -1.444  -13.447 6.917   1.0 50.30 ? 180 LEU A CG  1 Q8R3G1 UNP 180 L 
ATOM 1409 C CD1 . LEU A 1 180 ? -1.770  -12.932 8.319   1.0 50.30 ? 180 LEU A CD1 1 Q8R3G1 UNP 180 L 
ATOM 1410 C CD2 . LEU A 1 180 ? 0.077   -13.385 6.735   1.0 50.30 ? 180 LEU A CD2 1 Q8R3G1 UNP 180 L 
ATOM 1411 N N   . THR A 1 181 ? -1.805  -17.347 3.952   1.0 40.88 ? 181 THR A N   1 Q8R3G1 UNP 181 T 
ATOM 1412 C CA  . THR A 1 181 ? -1.578  -18.751 3.664   1.0 40.88 ? 181 THR A CA  1 Q8R3G1 UNP 181 T 
ATOM 1413 C C   . THR A 1 181 ? -0.614  -19.279 4.707   1.0 40.88 ? 181 THR A C   1 Q8R3G1 UNP 181 T 
ATOM 1414 C CB  . THR A 1 181 ? -0.982  -18.934 2.260   1.0 40.88 ? 181 THR A CB  1 Q8R3G1 UNP 181 T 
ATOM 1415 O O   . THR A 1 181 ? 0.525   -18.825 4.806   1.0 40.88 ? 181 THR A O   1 Q8R3G1 UNP 181 T 
ATOM 1416 C CG2 . THR A 1 181 ? -2.035  -18.677 1.182   1.0 40.88 ? 181 THR A CG2 1 Q8R3G1 UNP 181 T 
ATOM 1417 O OG1 . THR A 1 181 ? 0.065   -18.014 2.053   1.0 40.88 ? 181 THR A OG1 1 Q8R3G1 UNP 181 T 
ATOM 1418 N N   . ILE A 1 182 ? -1.113  -20.228 5.493   1.0 46.44 ? 182 ILE A N   1 Q8R3G1 UNP 182 I 
ATOM 1419 C CA  . ILE A 1 182 ? -0.327  -21.255 6.162   1.0 46.44 ? 182 ILE A CA  1 Q8R3G1 UNP 182 I 
ATOM 1420 C C   . ILE A 1 182 ? 0.780   -21.641 5.182   1.0 46.44 ? 182 ILE A C   1 Q8R3G1 UNP 182 I 
ATOM 1421 C CB  . ILE A 1 182 ? -1.271  -22.446 6.456   1.0 46.44 ? 182 ILE A CB  1 Q8R3G1 UNP 182 I 
ATOM 1422 O O   . ILE A 1 182 ? 0.479   -22.197 4.126   1.0 46.44 ? 182 ILE A O   1 Q8R3G1 UNP 182 I 
ATOM 1423 C CG1 . ILE A 1 182 ? -2.407  -22.031 7.425   1.0 46.44 ? 182 ILE A CG1 1 Q8R3G1 UNP 182 I 
ATOM 1424 C CG2 . ILE A 1 182 ? -0.506  -23.657 7.018   1.0 46.44 ? 182 ILE A CG2 1 Q8R3G1 UNP 182 I 
ATOM 1425 C CD1 . ILE A 1 182 ? -3.623  -22.963 7.367   1.0 46.44 ? 182 ILE A CD1 1 Q8R3G1 UNP 182 I 
ATOM 1426 N N   . GLU A 1 183 ? 2.020   -21.259 5.483   1.0 46.09 ? 183 GLU A N   1 Q8R3G1 UNP 183 E 
ATOM 1427 C CA  . GLU A 1 183 ? 3.176   -21.659 4.695   1.0 46.09 ? 183 GLU A CA  1 Q8R3G1 UNP 183 E 
ATOM 1428 C C   . GLU A 1 183 ? 3.121   -23.183 4.558   1.0 46.09 ? 183 GLU A C   1 Q8R3G1 UNP 183 E 
ATOM 1429 C CB  . GLU A 1 183 ? 4.482   -21.176 5.352   1.0 46.09 ? 183 GLU A CB  1 Q8R3G1 UNP 183 E 
ATOM 1430 O O   . GLU A 1 183 ? 3.089   -23.923 5.548   1.0 46.09 ? 183 GLU A O   1 Q8R3G1 UNP 183 E 
ATOM 1431 C CG  . GLU A 1 183 ? 4.624   -19.642 5.296   1.0 46.09 ? 183 GLU A CG  1 Q8R3G1 UNP 183 E 
ATOM 1432 C CD  . GLU A 1 183 ? 5.898   -19.105 5.977   1.0 46.09 ? 183 GLU A CD  1 Q8R3G1 UNP 183 E 
ATOM 1433 O OE1 . GLU A 1 183 ? 6.189   -17.903 5.783   1.0 46.09 ? 183 GLU A OE1 1 Q8R3G1 UNP 183 E 
ATOM 1434 O OE2 . GLU A 1 183 ? 6.552   -19.872 6.720   1.0 46.09 ? 183 GLU A OE2 1 Q8R3G1 UNP 183 E 
ATOM 1435 N N   . GLU A 1 184 ? 3.009   -23.635 3.310   1.0 47.71 ? 184 GLU A N   1 Q8R3G1 UNP 184 E 
ATOM 1436 C CA  . GLU A 1 184 ? 3.112   -25.026 2.893   1.0 47.71 ? 184 GLU A CA  1 Q8R3G1 UNP 184 E 
ATOM 1437 C C   . GLU A 1 184 ? 4.508   -25.536 3.276   1.0 47.71 ? 184 GLU A C   1 Q8R3G1 UNP 184 E 
ATOM 1438 C CB  . GLU A 1 184 ? 2.872   -25.128 1.375   1.0 47.71 ? 184 GLU A CB  1 Q8R3G1 UNP 184 E 
ATOM 1439 O O   . GLU A 1 184 ? 5.455   -25.486 2.500   1.0 47.71 ? 184 GLU A O   1 Q8R3G1 UNP 184 E 
ATOM 1440 C CG  . GLU A 1 184 ? 1.413   -24.892 0.959   1.0 47.71 ? 184 GLU A CG  1 Q8R3G1 UNP 184 E 
ATOM 1441 C CD  . GLU A 1 184 ? 1.224   -25.061 -0.558  1.0 47.71 ? 184 GLU A CD  1 Q8R3G1 UNP 184 E 
ATOM 1442 O OE1 . GLU A 1 184 ? 0.263   -25.765 -0.948  1.0 47.71 ? 184 GLU A OE1 1 Q8R3G1 UNP 184 E 
ATOM 1443 O OE2 . GLU A 1 184 ? 2.032   -24.482 -1.318  1.0 47.71 ? 184 GLU A OE2 1 Q8R3G1 UNP 184 E 
ATOM 1444 N N   . GLY A 1 185 ? 4.659   -25.949 4.532   1.0 44.16 ? 185 GLY A N   1 Q8R3G1 UNP 185 G 
ATOM 1445 C CA  . GLY A 1 185 ? 5.965   -26.250 5.107   1.0 44.16 ? 185 GLY A CA  1 Q8R3G1 UNP 185 G 
ATOM 1446 C C   . GLY A 1 185 ? 5.908   -26.976 6.445   1.0 44.16 ? 185 GLY A C   1 Q8R3G1 UNP 185 G 
ATOM 1447 O O   . GLY A 1 185 ? 6.826   -26.829 7.239   1.0 44.16 ? 185 GLY A O   1 Q8R3G1 UNP 185 G 
ATOM 1448 N N   . ASN A 1 186 ? 4.843   -27.739 6.729   1.0 43.26 ? 186 ASN A N   1 Q8R3G1 UNP 186 N 
ATOM 1449 C CA  . ASN A 1 186 ? 4.883   -28.817 7.727   1.0 43.26 ? 186 ASN A CA  1 Q8R3G1 UNP 186 N 
ATOM 1450 C C   . ASN A 1 186 ? 3.705   -29.795 7.540   1.0 43.26 ? 186 ASN A C   1 Q8R3G1 UNP 186 N 
ATOM 1451 C CB  . ASN A 1 186 ? 4.939   -28.253 9.167   1.0 43.26 ? 186 ASN A CB  1 Q8R3G1 UNP 186 N 
ATOM 1452 O O   . ASN A 1 186 ? 2.670   -29.689 8.201   1.0 43.26 ? 186 ASN A O   1 Q8R3G1 UNP 186 N 
ATOM 1453 C CG  . ASN A 1 186 ? 5.538   -29.257 10.136  1.0 43.26 ? 186 ASN A CG  1 Q8R3G1 UNP 186 N 
ATOM 1454 N ND2 . ASN A 1 186 ? 5.522   -28.974 11.414  1.0 43.26 ? 186 ASN A ND2 1 Q8R3G1 UNP 186 N 
ATOM 1455 O OD1 . ASN A 1 186 ? 6.035   -30.307 9.779   1.0 43.26 ? 186 ASN A OD1 1 Q8R3G1 UNP 186 N 
ATOM 1456 N N   . LEU A 1 187 ? 3.855   -30.750 6.618   1.0 53.02 ? 187 LEU A N   1 Q8R3G1 UNP 187 L 
ATOM 1457 C CA  . LEU A 1 187 ? 2.881   -31.821 6.357   1.0 53.02 ? 187 LEU A CA  1 Q8R3G1 UNP 187 L 
ATOM 1458 C C   . LEU A 1 187 ? 2.912   -32.964 7.400   1.0 53.02 ? 187 LEU A C   1 Q8R3G1 UNP 187 L 
ATOM 1459 C CB  . LEU A 1 187 ? 3.024   -32.317 4.897   1.0 53.02 ? 187 LEU A CB  1 Q8R3G1 UNP 187 L 
ATOM 1460 O O   . LEU A 1 187 ? 2.321   -34.008 7.152   1.0 53.02 ? 187 LEU A O   1 Q8R3G1 UNP 187 L 
ATOM 1461 C CG  . LEU A 1 187 ? 2.339   -31.424 3.842   1.0 53.02 ? 187 LEU A CG  1 Q8R3G1 UNP 187 L 
ATOM 1462 C CD1 . LEU A 1 187 ? 2.733   -31.886 2.438   1.0 53.02 ? 187 LEU A CD1 1 Q8R3G1 UNP 187 L 
ATOM 1463 C CD2 . LEU A 1 187 ? 0.809   -31.486 3.932   1.0 53.02 ? 187 LEU A CD2 1 Q8R3G1 UNP 187 L 
ATOM 1464 N N   . ASP A 1 188 ? 3.505   -32.757 8.585   1.0 50.93 ? 188 ASP A N   1 Q8R3G1 UNP 188 D 
ATOM 1465 C CA  . ASP A 1 188 ? 3.598   -33.769 9.657   1.0 50.93 ? 188 ASP A CA  1 Q8R3G1 UNP 188 D 
ATOM 1466 C C   . ASP A 1 188 ? 2.994   -33.342 11.009  1.0 50.93 ? 188 ASP A C   1 Q8R3G1 UNP 188 D 
ATOM 1467 C CB  . ASP A 1 188 ? 5.047   -34.254 9.793   1.0 50.93 ? 188 ASP A CB  1 Q8R3G1 UNP 188 D 
ATOM 1468 O O   . ASP A 1 188 ? 3.217   -33.976 12.043  1.0 50.93 ? 188 ASP A O   1 Q8R3G1 UNP 188 D 
ATOM 1469 C CG  . ASP A 1 188 ? 5.441   -35.173 8.637   1.0 50.93 ? 188 ASP A CG  1 Q8R3G1 UNP 188 D 
ATOM 1470 O OD1 . ASP A 1 188 ? 4.698   -36.154 8.403   1.0 50.93 ? 188 ASP A OD1 1 Q8R3G1 UNP 188 D 
ATOM 1471 O OD2 . ASP A 1 188 ? 6.499   -34.905 8.028   1.0 50.93 ? 188 ASP A OD2 1 Q8R3G1 UNP 188 D 
ATOM 1472 N N   . ILE A 1 189 ? 2.152   -32.305 11.044  1.0 53.68 ? 189 ILE A N   1 Q8R3G1 UNP 189 I 
ATOM 1473 C CA  . ILE A 1 189 ? 1.346   -32.039 12.244  1.0 53.68 ? 189 ILE A CA  1 Q8R3G1 UNP 189 I 
ATOM 1474 C C   . ILE A 1 189 ? 0.089   -32.898 12.158  1.0 53.68 ? 189 ILE A C   1 Q8R3G1 UNP 189 I 
ATOM 1475 C CB  . ILE A 1 189 ? 1.088   -30.538 12.458  1.0 53.68 ? 189 ILE A CB  1 Q8R3G1 UNP 189 I 
ATOM 1476 O O   . ILE A 1 189 ? -0.870  -32.558 11.463  1.0 53.68 ? 189 ILE A O   1 Q8R3G1 UNP 189 I 
ATOM 1477 C CG1 . ILE A 1 189 ? 2.434   -29.820 12.709  1.0 53.68 ? 189 ILE A CG1 1 Q8R3G1 UNP 189 I 
ATOM 1478 C CG2 . ILE A 1 189 ? 0.155   -30.315 13.669  1.0 53.68 ? 189 ILE A CG2 1 Q8R3G1 UNP 189 I 
ATOM 1479 C CD1 . ILE A 1 189 ? 2.375   -28.330 12.364  1.0 53.68 ? 189 ILE A CD1 1 Q8R3G1 UNP 189 I 
ATOM 1480 N N   . GLN A 1 190 ? 0.102   -34.020 12.887  1.0 48.42 ? 190 GLN A N   1 Q8R3G1 UNP 190 Q 
ATOM 1481 C CA  . GLN A 1 190 ? -1.072  -34.844 13.171  1.0 48.42 ? 190 GLN A CA  1 Q8R3G1 UNP 190 Q 
ATOM 1482 C C   . GLN A 1 190 ? -2.242  -33.933 13.536  1.0 48.42 ? 190 GLN A C   1 Q8R3G1 UNP 190 Q 
ATOM 1483 C CB  . GLN A 1 190 ? -0.804  -35.798 14.348  1.0 48.42 ? 190 GLN A CB  1 Q8R3G1 UNP 190 Q 
ATOM 1484 O O   . GLN A 1 190 ? -2.333  -33.425 14.652  1.0 48.42 ? 190 GLN A O   1 Q8R3G1 UNP 190 Q 
ATOM 1485 C CG  . GLN A 1 190 ? 0.105   -36.976 13.988  1.0 48.42 ? 190 GLN A CG  1 Q8R3G1 UNP 190 Q 
ATOM 1486 C CD  . GLN A 1 190 ? 0.380   -37.888 15.183  1.0 48.42 ? 190 GLN A CD  1 Q8R3G1 UNP 190 Q 
ATOM 1487 N NE2 . GLN A 1 190 ? 1.404   -38.706 15.110  1.0 48.42 ? 190 GLN A NE2 1 Q8R3G1 UNP 190 Q 
ATOM 1488 O OE1 . GLN A 1 190 ? -0.317  -37.894 16.187  1.0 48.42 ? 190 GLN A OE1 1 Q8R3G1 UNP 190 Q 
ATOM 1489 N N   . ARG A 1 191 ? -3.147  -33.714 12.578  1.0 52.81 ? 191 ARG A N   1 Q8R3G1 UNP 191 R 
ATOM 1490 C CA  . ARG A 1 191 ? -4.399  -33.000 12.798  1.0 52.81 ? 191 ARG A CA  1 Q8R3G1 UNP 191 R 
ATOM 1491 C C   . ARG A 1 191 ? -5.110  -33.758 13.916  1.0 52.81 ? 191 ARG A C   1 Q8R3G1 UNP 191 R 
ATOM 1492 C CB  . ARG A 1 191 ? -5.178  -32.983 11.470  1.0 52.81 ? 191 ARG A CB  1 Q8R3G1 UNP 191 R 
ATOM 1493 O O   . ARG A 1 191 ? -5.549  -34.885 13.663  1.0 52.81 ? 191 ARG A O   1 Q8R3G1 UNP 191 R 
ATOM 1494 C CG  . ARG A 1 191 ? -6.303  -31.942 11.424  1.0 52.81 ? 191 ARG A CG  1 Q8R3G1 UNP 191 R 
ATOM 1495 C CD  . ARG A 1 191 ? -6.954  -31.963 10.032  1.0 52.81 ? 191 ARG A CD  1 Q8R3G1 UNP 191 R 
ATOM 1496 N NE  . ARG A 1 191 ? -7.618  -30.684 9.713   1.0 52.81 ? 191 ARG A NE  1 Q8R3G1 UNP 191 R 
ATOM 1497 N NH1 . ARG A 1 191 ? -9.789  -31.410 9.482   1.0 52.81 ? 191 ARG A NH1 1 Q8R3G1 UNP 191 R 
ATOM 1498 N NH2 . ARG A 1 191 ? -9.274  -29.284 9.033   1.0 52.81 ? 191 ARG A NH2 1 Q8R3G1 UNP 191 R 
ATOM 1499 C CZ  . ARG A 1 191 ? -8.888  -30.468 9.417   1.0 52.81 ? 191 ARG A CZ  1 Q8R3G1 UNP 191 R 
ATOM 1500 N N   . PRO A 1 192 ? -5.246  -33.214 15.142  1.0 54.21 ? 192 PRO A N   1 Q8R3G1 UNP 192 P 
ATOM 1501 C CA  . PRO A 1 192 ? -6.070  -33.889 16.118  1.0 54.21 ? 192 PRO A CA  1 Q8R3G1 UNP 192 P 
ATOM 1502 C C   . PRO A 1 192 ? -7.454  -33.926 15.482  1.0 54.21 ? 192 PRO A C   1 Q8R3G1 UNP 192 P 
ATOM 1503 C CB  . PRO A 1 192 ? -5.974  -33.065 17.404  1.0 54.21 ? 192 PRO A CB  1 Q8R3G1 UNP 192 P 
ATOM 1504 O O   . PRO A 1 192 ? -7.982  -32.885 15.076  1.0 54.21 ? 192 PRO A O   1 Q8R3G1 UNP 192 P 
ATOM 1505 C CG  . PRO A 1 192 ? -5.624  -31.659 16.914  1.0 54.21 ? 192 PRO A CG  1 Q8R3G1 UNP 192 P 
ATOM 1506 C CD  . PRO A 1 192 ? -4.843  -31.897 15.620  1.0 54.21 ? 192 PRO A CD  1 Q8R3G1 UNP 192 P 
ATOM 1507 N N   . LYS A 1 193 ? -8.024  -35.125 15.317  1.0 51.37 ? 193 LYS A N   1 Q8R3G1 UNP 193 K 
ATOM 1508 C CA  . LYS A 1 193 ? -9.419  -35.302 14.909  1.0 51.37 ? 193 LYS A CA  1 Q8R3G1 UNP 193 K 
ATOM 1509 C C   . LYS A 1 193 ? -10.310 -34.724 16.009  1.0 51.37 ? 193 LYS A C   1 Q8R3G1 UNP 193 K 
ATOM 1510 C CB  . LYS A 1 193 ? -9.749  -36.780 14.611  1.0 51.37 ? 193 LYS A CB  1 Q8R3G1 UNP 193 K 
ATOM 1511 O O   . LYS A 1 193 ? -10.969 -35.448 16.747  1.0 51.37 ? 193 LYS A O   1 Q8R3G1 UNP 193 K 
ATOM 1512 C CG  . LYS A 1 193 ? -9.138  -37.308 13.302  1.0 51.37 ? 193 LYS A CG  1 Q8R3G1 UNP 193 K 
ATOM 1513 C CD  . LYS A 1 193 ? -9.886  -38.565 12.819  1.0 51.37 ? 193 LYS A CD  1 Q8R3G1 UNP 193 K 
ATOM 1514 C CE  . LYS A 1 193 ? -9.291  -39.087 11.503  1.0 51.37 ? 193 LYS A CE  1 Q8R3G1 UNP 193 K 
ATOM 1515 N NZ  . LYS A 1 193 ? -10.010 -40.282 10.984  1.0 51.37 ? 193 LYS A NZ  1 Q8R3G1 UNP 193 K 
ATOM 1516 N N   . ARG A 1 194 ? -10.345 -33.397 16.138  1.0 56.96 ? 194 ARG A N   1 Q8R3G1 UNP 194 R 
ATOM 1517 C CA  . ARG A 1 194 ? -11.355 -32.693 16.909  1.0 56.96 ? 194 ARG A CA  1 Q8R3G1 UNP 194 R 
ATOM 1518 C C   . ARG A 1 194 ? -12.613 -32.802 16.070  1.0 56.96 ? 194 ARG A C   1 Q8R3G1 UNP 194 R 
ATOM 1519 C CB  . ARG A 1 194 ? -10.931 -31.250 17.249  1.0 56.96 ? 194 ARG A CB  1 Q8R3G1 UNP 194 R 
ATOM 1520 O O   . ARG A 1 194 ? -12.865 -31.987 15.186  1.0 56.96 ? 194 ARG A O   1 Q8R3G1 UNP 194 R 
ATOM 1521 C CG  . ARG A 1 194 ? -9.725  -31.233 18.207  1.0 56.96 ? 194 ARG A CG  1 Q8R3G1 UNP 194 R 
ATOM 1522 C CD  . ARG A 1 194 ? -9.357  -29.831 18.720  1.0 56.96 ? 194 ARG A CD  1 Q8R3G1 UNP 194 R 
ATOM 1523 N NE  . ARG A 1 194 ? -10.125 -29.429 19.922  1.0 56.96 ? 194 ARG A NE  1 Q8R3G1 UNP 194 R 
ATOM 1524 N NH1 . ARG A 1 194 ? -8.620  -27.883 20.738  1.0 56.96 ? 194 ARG A NH1 1 Q8R3G1 UNP 194 R 
ATOM 1525 N NH2 . ARG A 1 194 ? -10.473 -28.308 21.888  1.0 56.96 ? 194 ARG A NH2 1 Q8R3G1 UNP 194 R 
ATOM 1526 C CZ  . ARG A 1 194 ? -9.738  -28.548 20.838  1.0 56.96 ? 194 ARG A CZ  1 Q8R3G1 UNP 194 R 
ATOM 1527 N N   . LYS A 1 195 ? -13.377 -33.871 16.328  1.0 57.07 ? 195 LYS A N   1 Q8R3G1 UNP 195 K 
ATOM 1528 C CA  . LYS A 1 195 ? -14.816 -33.891 16.072  1.0 57.07 ? 195 LYS A CA  1 Q8R3G1 UNP 195 K 
ATOM 1529 C C   . LYS A 1 195 ? -15.325 -32.510 16.477  1.0 57.07 ? 195 LYS A C   1 Q8R3G1 UNP 195 K 
ATOM 1530 C CB  . LYS A 1 195 ? -15.508 -34.972 16.930  1.0 57.07 ? 195 LYS A CB  1 Q8R3G1 UNP 195 K 
ATOM 1531 O O   . LYS A 1 195 ? -15.167 -32.132 17.639  1.0 57.07 ? 195 LYS A O   1 Q8R3G1 UNP 195 K 
ATOM 1532 C CG  . LYS A 1 195 ? -15.407 -36.395 16.357  1.0 57.07 ? 195 LYS A CG  1 Q8R3G1 UNP 195 K 
ATOM 1533 C CD  . LYS A 1 195 ? -16.236 -37.383 17.202  1.0 57.07 ? 195 LYS A CD  1 Q8R3G1 UNP 195 K 
ATOM 1534 C CE  . LYS A 1 195 ? -16.324 -38.765 16.535  1.0 57.07 ? 195 LYS A CE  1 Q8R3G1 UNP 195 K 
ATOM 1535 N NZ  . LYS A 1 195 ? -17.168 -39.716 17.311  1.0 57.07 ? 195 LYS A NZ  1 Q8R3G1 UNP 195 K 
ATOM 1536 N N   . ARG A 1 196 ? -15.866 -31.749 15.522  1.0 59.93 ? 196 ARG A N   1 Q8R3G1 UNP 196 R 
ATOM 1537 C CA  . ARG A 1 196 ? -16.655 -30.560 15.834  1.0 59.93 ? 196 ARG A CA  1 Q8R3G1 UNP 196 R 
ATOM 1538 C C   . ARG A 1 196 ? -17.762 -31.048 16.763  1.0 59.93 ? 196 ARG A C   1 Q8R3G1 UNP 196 R 
ATOM 1539 C CB  . ARG A 1 196 ? -17.230 -29.929 14.549  1.0 59.93 ? 196 ARG A CB  1 Q8R3G1 UNP 196 R 
ATOM 1540 O O   . ARG A 1 196 ? -18.692 -31.710 16.317  1.0 59.93 ? 196 ARG A O   1 Q8R3G1 UNP 196 R 
ATOM 1541 C CG  . ARG A 1 196 ? -16.197 -29.107 13.759  1.0 59.93 ? 196 ARG A CG  1 Q8R3G1 UNP 196 R 
ATOM 1542 C CD  . ARG A 1 196 ? -16.865 -28.408 12.562  1.0 59.93 ? 196 ARG A CD  1 Q8R3G1 UNP 196 R 
ATOM 1543 N NE  . ARG A 1 196 ? -16.032 -27.317 12.012  1.0 59.93 ? 196 ARG A NE  1 Q8R3G1 UNP 196 R 
ATOM 1544 N NH1 . ARG A 1 196 ? -17.535 -26.549 10.443  1.0 59.93 ? 196 ARG A NH1 1 Q8R3G1 UNP 196 R 
ATOM 1545 N NH2 . ARG A 1 196 ? -15.608 -25.473 10.731  1.0 59.93 ? 196 ARG A NH2 1 Q8R3G1 UNP 196 R 
ATOM 1546 C CZ  . ARG A 1 196 ? -16.393 -26.458 11.068  1.0 59.93 ? 196 ARG A CZ  1 Q8R3G1 UNP 196 R 
ATOM 1547 N N   . LYS A 1 197 ? -17.609 -30.828 18.069  1.0 59.75 ? 197 LYS A N   1 Q8R3G1 UNP 197 K 
ATOM 1548 C CA  . LYS A 1 197 ? -18.744 -30.914 18.975  1.0 59.75 ? 197 LYS A CA  1 Q8R3G1 UNP 197 K 
ATOM 1549 C C   . LYS A 1 197 ? -19.611 -29.737 18.560  1.0 59.75 ? 197 LYS A C   1 Q8R3G1 UNP 197 K 
ATOM 1550 C CB  . LYS A 1 197 ? -18.314 -30.843 20.454  1.0 59.75 ? 197 LYS A CB  1 Q8R3G1 UNP 197 K 
ATOM 1551 O O   . LYS A 1 197 ? -19.192 -28.596 18.739  1.0 59.75 ? 197 LYS A O   1 Q8R3G1 UNP 197 K 
ATOM 1552 C CG  . LYS A 1 197 ? -17.647 -32.139 20.957  1.0 59.75 ? 197 LYS A CG  1 Q8R3G1 UNP 197 K 
ATOM 1553 C CD  . LYS A 1 197 ? -17.468 -32.105 22.486  1.0 59.75 ? 197 LYS A CD  1 Q8R3G1 UNP 197 K 
ATOM 1554 C CE  . LYS A 1 197 ? -16.904 -33.424 23.040  1.0 59.75 ? 197 LYS A CE  1 Q8R3G1 UNP 197 K 
ATOM 1555 N NZ  . LYS A 1 197 ? -16.885 -33.431 24.530  1.0 59.75 ? 197 LYS A NZ  1 Q8R3G1 UNP 197 K 
ATOM 1556 N N   . ASN A 1 198 ? -20.751 -30.012 17.928  1.0 60.53 ? 198 ASN A N   1 Q8R3G1 UNP 198 N 
ATOM 1557 C CA  . ASN A 1 198 ? -21.826 -29.033 17.884  1.0 60.53 ? 198 ASN A CA  1 Q8R3G1 UNP 198 N 
ATOM 1558 C C   . ASN A 1 198 ? -21.995 -28.543 19.321  1.0 60.53 ? 198 ASN A C   1 Q8R3G1 UNP 198 N 
ATOM 1559 C CB  . ASN A 1 198 ? -23.128 -29.666 17.350  1.0 60.53 ? 198 ASN A CB  1 Q8R3G1 UNP 198 N 
ATOM 1560 O O   . ASN A 1 198 ? -22.241 -29.350 20.219  1.0 60.53 ? 198 ASN A O   1 Q8R3G1 UNP 198 N 
ATOM 1561 C CG  . ASN A 1 198 ? -23.280 -29.578 15.841  1.0 60.53 ? 198 ASN A CG  1 Q8R3G1 UNP 198 N 
ATOM 1562 N ND2 . ASN A 1 198 ? -24.418 -29.970 15.319  1.0 60.53 ? 198 ASN A ND2 1 Q8R3G1 UNP 198 N 
ATOM 1563 O OD1 . ASN A 1 198 ? -22.391 -29.159 15.120  1.0 60.53 ? 198 ASN A OD1 1 Q8R3G1 UNP 198 N 
ATOM 1564 N N   . SER A 1 199 ? -21.759 -27.252 19.534  1.0 64.72 ? 199 SER A N   1 Q8R3G1 UNP 199 S 
ATOM 1565 C CA  . SER A 1 199 ? -22.117 -26.589 20.776  1.0 64.72 ? 199 SER A CA  1 Q8R3G1 UNP 199 S 
ATOM 1566 C C   . SER A 1 199 ? -23.635 -26.676 20.866  1.0 64.72 ? 199 SER A C   1 Q8R3G1 UNP 199 S 
ATOM 1567 C CB  . SER A 1 199 ? -21.637 -25.137 20.753  1.0 64.72 ? 199 SER A CB  1 Q8R3G1 UNP 199 S 
ATOM 1568 O O   . SER A 1 199 ? -24.350 -25.928 20.204  1.0 64.72 ? 199 SER A O   1 Q8R3G1 UNP 199 S 
ATOM 1569 O OG  . SER A 1 199 ? -21.993 -24.526 21.969  1.0 64.72 ? 199 SER A OG  1 Q8R3G1 UNP 199 S 
ATOM 1570 N N   . ARG A 1 200 ? -24.129 -27.696 21.568  1.0 68.13 ? 200 ARG A N   1 Q8R3G1 UNP 200 R 
ATOM 1571 C CA  . ARG A 1 200 ? -25.532 -27.787 21.933  1.0 68.13 ? 200 ARG A CA  1 Q8R3G1 UNP 200 R 
ATOM 1572 C C   . ARG A 1 200 ? -25.655 -26.981 23.211  1.0 68.13 ? 200 ARG A C   1 Q8R3G1 UNP 200 R 
ATOM 1573 C CB  . ARG A 1 200 ? -25.972 -29.256 22.065  1.0 68.13 ? 200 ARG A CB  1 Q8R3G1 UNP 200 R 
ATOM 1574 O O   . ARG A 1 200 ? -25.119 -27.391 24.234  1.0 68.13 ? 200 ARG A O   1 Q8R3G1 UNP 200 R 
ATOM 1575 C CG  . ARG A 1 200 ? -27.504 -29.364 22.134  1.0 68.13 ? 200 ARG A CG  1 Q8R3G1 UNP 200 R 
ATOM 1576 C CD  . ARG A 1 200 ? -28.005 -30.814 22.019  1.0 68.13 ? 200 ARG A CD  1 Q8R3G1 UNP 200 R 
ATOM 1577 N NE  . ARG A 1 200 ? -28.502 -31.345 23.304  1.0 68.13 ? 200 ARG A NE  1 Q8R3G1 UNP 200 R 
ATOM 1578 N NH1 . ARG A 1 200 ? -29.914 -32.957 22.456  1.0 68.13 ? 200 ARG A NH1 1 Q8R3G1 UNP 200 R 
ATOM 1579 N NH2 . ARG A 1 200 ? -29.828 -32.616 24.656  1.0 68.13 ? 200 ARG A NH2 1 Q8R3G1 UNP 200 R 
ATOM 1580 C CZ  . ARG A 1 200 ? -29.406 -32.301 23.465  1.0 68.13 ? 200 ARG A CZ  1 Q8R3G1 UNP 200 R 
ATOM 1581 N N   . VAL A 1 201 ? -26.309 -25.828 23.118  1.0 71.62 ? 201 VAL A N   1 Q8R3G1 UNP 201 V 
ATOM 1582 C CA  . VAL A 1 201 ? -26.766 -25.086 24.291  1.0 71.62 ? 201 VAL A CA  1 Q8R3G1 UNP 201 V 
ATOM 1583 C C   . VAL A 1 201 ? -27.696 -26.026 25.056  1.0 71.62 ? 201 VAL A C   1 Q8R3G1 UNP 201 V 
ATOM 1584 C CB  . VAL A 1 201 ? -27.476 -23.780 23.878  1.0 71.62 ? 201 VAL A CB  1 Q8R3G1 UNP 201 V 
ATOM 1585 O O   . VAL A 1 201 ? -28.737 -26.433 24.544  1.0 71.62 ? 201 VAL A O   1 Q8R3G1 UNP 201 V 
ATOM 1586 C CG1 . VAL A 1 201 ? -27.973 -22.996 25.096  1.0 71.62 ? 201 VAL A CG1 1 Q8R3G1 UNP 201 V 
ATOM 1587 C CG2 . VAL A 1 201 ? -26.527 -22.873 23.079  1.0 71.62 ? 201 VAL A CG2 1 Q8R3G1 UNP 201 V 
ATOM 1588 N N   . THR A 1 202 ? -27.264 -26.456 26.232  1.0 72.97 ? 202 THR A N   1 Q8R3G1 UNP 202 T 
ATOM 1589 C CA  . THR A 1 202 ? -28.096 -27.136 27.223  1.0 72.97 ? 202 THR A CA  1 Q8R3G1 UNP 202 T 
ATOM 1590 C C   . THR A 1 202 ? -28.358 -26.128 28.322  1.0 72.97 ? 202 THR A C   1 Q8R3G1 UNP 202 T 
ATOM 1591 C CB  . THR A 1 202 ? -27.419 -28.396 27.789  1.0 72.97 ? 202 THR A CB  1 Q8R3G1 UNP 202 T 
ATOM 1592 O O   . THR A 1 202 ? -27.407 -25.610 28.905  1.0 72.97 ? 202 THR A O   1 Q8R3G1 UNP 202 T 
ATOM 1593 C CG2 . THR A 1 202 ? -27.493 -29.553 26.789  1.0 72.97 ? 202 THR A CG2 1 Q8R3G1 UNP 202 T 
ATOM 1594 O OG1 . THR A 1 202 ? -26.053 -28.165 28.057  1.0 72.97 ? 202 THR A OG1 1 Q8R3G1 UNP 202 T 
ATOM 1595 N N   . PHE A 1 203 ? -29.627 -25.825 28.568  1.0 68.33 ? 203 PHE A N   1 Q8R3G1 UNP 203 F 
ATOM 1596 C CA  . PHE A 1 203 ? -30.028 -25.128 29.780  1.0 68.33 ? 203 PHE A CA  1 Q8R3G1 UNP 203 F 
ATOM 1597 C C   . PHE A 1 203 ? -29.813 -26.089 30.950  1.0 68.33 ? 203 PHE A C   1 Q8R3G1 UNP 203 F 
ATOM 1598 C CB  . PHE A 1 203 ? -31.486 -24.666 29.637  1.0 68.33 ? 203 PHE A CB  1 Q8R3G1 UNP 203 F 
ATOM 1599 O O   . PHE A 1 203 ? -30.152 -27.269 30.832  1.0 68.33 ? 203 PHE A O   1 Q8R3G1 UNP 203 F 
ATOM 1600 C CG  . PHE A 1 203 ? -31.677 -23.649 28.523  1.0 68.33 ? 203 PHE A CG  1 Q8R3G1 UNP 203 F 
ATOM 1601 C CD1 . PHE A 1 203 ? -31.414 -22.290 28.771  1.0 68.33 ? 203 PHE A CD1 1 Q8R3G1 UNP 203 F 
ATOM 1602 C CD2 . PHE A 1 203 ? -32.081 -24.055 27.235  1.0 68.33 ? 203 PHE A CD2 1 Q8R3G1 UNP 203 F 
ATOM 1603 C CE1 . PHE A 1 203 ? -31.550 -21.342 27.741  1.0 68.33 ? 203 PHE A CE1 1 Q8R3G1 UNP 203 F 
ATOM 1604 C CE2 . PHE A 1 203 ? -32.213 -23.107 26.202  1.0 68.33 ? 203 PHE A CE2 1 Q8R3G1 UNP 203 F 
ATOM 1605 C CZ  . PHE A 1 203 ? -31.948 -21.750 26.456  1.0 68.33 ? 203 PHE A CZ  1 Q8R3G1 UNP 203 F 
ATOM 1606 N N   . SER A 1 204 ? -29.186 -25.618 32.027  1.0 72.96 ? 204 SER A N   1 Q8R3G1 UNP 204 S 
ATOM 1607 C CA  . SER A 1 204 ? -29.199 -26.347 33.293  1.0 72.96 ? 204 SER A CA  1 Q8R3G1 UNP 204 S 
ATOM 1608 C C   . SER A 1 204 ? -30.662 -26.490 33.721  1.0 72.96 ? 204 SER A C   1 Q8R3G1 UNP 204 S 
ATOM 1609 C CB  . SER A 1 204 ? -28.403 -25.592 34.365  1.0 72.96 ? 204 SER A CB  1 Q8R3G1 UNP 204 S 
ATOM 1610 O O   . SER A 1 204 ? -31.362 -25.487 33.788  1.0 72.96 ? 204 SER A O   1 Q8R3G1 UNP 204 S 
ATOM 1611 O OG  . SER A 1 204 ? -27.039 -25.462 33.989  1.0 72.96 ? 204 SER A OG  1 Q8R3G1 UNP 204 S 
ATOM 1612 N N   . GLU A 1 205 ? -31.129 -27.720 33.946  1.0 70.92 ? 205 GLU A N   1 Q8R3G1 UNP 205 E 
ATOM 1613 C CA  . GLU A 1 205 ? -32.456 -27.991 34.538  1.0 70.92 ? 205 GLU A CA  1 Q8R3G1 UNP 205 E 
ATOM 1614 C C   . GLU A 1 205 ? -32.478 -27.723 36.051  1.0 70.92 ? 205 GLU A C   1 Q8R3G1 UNP 205 E 
ATOM 1615 C CB  . GLU A 1 205 ? -32.897 -29.437 34.224  1.0 70.92 ? 205 GLU A CB  1 Q8R3G1 UNP 205 E 
ATOM 1616 O O   . GLU A 1 205 ? -33.534 -27.785 36.676  1.0 70.92 ? 205 GLU A O   1 Q8R3G1 UNP 205 E 
ATOM 1617 C CG  . GLU A 1 205 ? -33.661 -29.530 32.893  1.0 70.92 ? 205 GLU A CG  1 Q8R3G1 UNP 205 E 
ATOM 1618 C CD  . GLU A 1 205 ? -34.026 -30.969 32.475  1.0 70.92 ? 205 GLU A CD  1 Q8R3G1 UNP 205 E 
ATOM 1619 O OE1 . GLU A 1 205 ? -34.945 -31.112 31.631  1.0 70.92 ? 205 GLU A OE1 1 Q8R3G1 UNP 205 E 
ATOM 1620 O OE2 . GLU A 1 205 ? -33.337 -31.926 32.899  1.0 70.92 ? 205 GLU A OE2 1 Q8R3G1 UNP 205 E 
ATOM 1621 N N   . ASP A 1 206 ? -31.325 -27.397 36.635  1.0 68.75 ? 206 ASP A N   1 Q8R3G1 UNP 206 D 
ATOM 1622 C CA  . ASP A 1 206 ? -31.228 -26.913 38.002  1.0 68.75 ? 206 ASP A CA  1 Q8R3G1 UNP 206 D 
ATOM 1623 C C   . ASP A 1 206 ? -31.597 -25.425 38.018  1.0 68.75 ? 206 ASP A C   1 Q8R3G1 UNP 206 D 
ATOM 1624 C CB  . ASP A 1 206 ? -29.829 -27.201 38.567  1.0 68.75 ? 206 ASP A CB  1 Q8R3G1 UNP 206 D 
ATOM 1625 O O   . ASP A 1 206 ? -30.753 -24.546 37.826  1.0 68.75 ? 206 ASP A O   1 Q8R3G1 UNP 206 D 
ATOM 1626 C CG  . ASP A 1 206 ? -29.490 -28.698 38.567  1.0 68.75 ? 206 ASP A CG  1 Q8R3G1 UNP 206 D 
ATOM 1627 O OD1 . ASP A 1 206 ? -30.322 -29.505 39.039  1.0 68.75 ? 206 ASP A OD1 1 Q8R3G1 UNP 206 D 
ATOM 1628 O OD2 . ASP A 1 206 ? -28.383 -29.037 38.084  1.0 68.75 ? 206 ASP A OD2 1 Q8R3G1 UNP 206 D 
ATOM 1629 N N   . ASP A 1 207 ? -32.885 -25.150 38.213  1.0 67.28 ? 207 ASP A N   1 Q8R3G1 UNP 207 D 
ATOM 1630 C CA  . ASP A 1 207 ? -33.335 -23.837 38.654  1.0 67.28 ? 207 ASP A CA  1 Q8R3G1 UNP 207 D 
ATOM 1631 C C   . ASP A 1 207 ? -32.674 -23.558 40.015  1.0 67.28 ? 207 ASP A C   1 Q8R3G1 UNP 207 D 
ATOM 1632 C CB  . ASP A 1 207 ? -34.875 -23.785 38.749  1.0 67.28 ? 207 ASP A CB  1 Q8R3G1 UNP 207 D 
ATOM 1633 O O   . ASP A 1 207 ? -33.044 -24.138 41.040  1.0 67.28 ? 207 ASP A O   1 Q8R3G1 UNP 207 D 
ATOM 1634 C CG  . ASP A 1 207 ? -35.596 -23.664 37.397  1.0 67.28 ? 207 ASP A CG  1 Q8R3G1 UNP 207 D 
ATOM 1635 O OD1 . ASP A 1 207 ? -35.085 -22.940 36.512  1.0 67.28 ? 207 ASP A OD1 1 Q8R3G1 UNP 207 D 
ATOM 1636 O OD2 . ASP A 1 207 ? -36.713 -24.223 37.285  1.0 67.28 ? 207 ASP A OD2 1 Q8R3G1 UNP 207 D 
ATOM 1637 N N   . GLU A 1 208 ? -31.670 -22.676 40.040  1.0 69.67 ? 208 GLU A N   1 Q8R3G1 UNP 208 E 
ATOM 1638 C CA  . GLU A 1 208 ? -31.189 -22.063 41.279  1.0 69.67 ? 208 GLU A CA  1 Q8R3G1 UNP 208 E 
ATOM 1639 C C   . GLU A 1 208 ? -32.321 -21.189 41.834  1.0 69.67 ? 208 GLU A C   1 Q8R3G1 UNP 208 E 
ATOM 1640 C CB  . GLU A 1 208 ? -29.883 -21.270 41.073  1.0 69.67 ? 208 GLU A CB  1 Q8R3G1 UNP 208 E 
ATOM 1641 O O   . GLU A 1 208 ? -32.455 -20.003 41.526  1.0 69.67 ? 208 GLU A O   1 Q8R3G1 UNP 208 E 
ATOM 1642 C CG  . GLU A 1 208 ? -28.644 -22.175 40.931  1.0 69.67 ? 208 GLU A CG  1 Q8R3G1 UNP 208 E 
ATOM 1643 C CD  . GLU A 1 208 ? -27.316 -21.401 40.787  1.0 69.67 ? 208 GLU A CD  1 Q8R3G1 UNP 208 E 
ATOM 1644 O OE1 . GLU A 1 208 ? -26.265 -22.071 40.640  1.0 69.67 ? 208 GLU A OE1 1 Q8R3G1 UNP 208 E 
ATOM 1645 O OE2 . GLU A 1 208 ? -27.327 -20.147 40.817  1.0 69.67 ? 208 GLU A OE2 1 Q8R3G1 UNP 208 E 
ATOM 1646 N N   . ILE A 1 209 ? -33.191 -21.809 42.631  1.0 69.46 ? 209 ILE A N   1 Q8R3G1 UNP 209 I 
ATOM 1647 C CA  . ILE A 1 209 ? -34.228 -21.122 43.391  1.0 69.46 ? 209 ILE A CA  1 Q8R3G1 UNP 209 I 
ATOM 1648 C C   . ILE A 1 209 ? -33.514 -20.351 44.502  1.0 69.46 ? 209 ILE A C   1 Q8R3G1 UNP 209 I 
ATOM 1649 C CB  . ILE A 1 209 ? -35.294 -22.108 43.923  1.0 69.46 ? 209 ILE A CB  1 Q8R3G1 UNP 209 I 
ATOM 1650 O O   . ILE A 1 209 ? -33.186 -20.898 45.552  1.0 69.46 ? 209 ILE A O   1 Q8R3G1 UNP 209 I 
ATOM 1651 C CG1 . ILE A 1 209 ? -35.976 -22.874 42.763  1.0 69.46 ? 209 ILE A CG1 1 Q8R3G1 UNP 209 I 
ATOM 1652 C CG2 . ILE A 1 209 ? -36.356 -21.344 44.743  1.0 69.46 ? 209 ILE A CG2 1 Q8R3G1 UNP 209 I 
ATOM 1653 C CD1 . ILE A 1 209 ? -36.846 -24.052 43.219  1.0 69.46 ? 209 ILE A CD1 1 Q8R3G1 UNP 209 I 
ATOM 1654 N N   . ILE A 1 210 ? -33.245 -19.071 44.248  1.0 66.79 ? 210 ILE A N   1 Q8R3G1 UNP 210 I 
ATOM 1655 C CA  . ILE A 1 210 ? -32.816 -18.133 45.283  1.0 66.79 ? 210 ILE A CA  1 Q8R3G1 UNP 210 I 
ATOM 1656 C C   . ILE A 1 210 ? -34.032 -17.875 46.166  1.0 66.79 ? 210 ILE A C   1 Q8R3G1 UNP 210 I 
ATOM 1657 C CB  . ILE A 1 210 ? -32.259 -16.830 44.671  1.0 66.79 ? 210 ILE A CB  1 Q8R3G1 UNP 210 I 
ATOM 1658 O O   . ILE A 1 210 ? -35.014 -17.272 45.718  1.0 66.79 ? 210 ILE A O   1 Q8R3G1 UNP 210 I 
ATOM 1659 C CG1 . ILE A 1 210 ? -31.073 -17.117 43.722  1.0 66.79 ? 210 ILE A CG1 1 Q8R3G1 UNP 210 I 
ATOM 1660 C CG2 . ILE A 1 210 ? -31.826 -15.880 45.800  1.0 66.79 ? 210 ILE A CG2 1 Q8R3G1 UNP 210 I 
ATOM 1661 C CD1 . ILE A 1 210 ? -30.566 -15.881 42.967  1.0 66.79 ? 210 ILE A CD1 1 Q8R3G1 UNP 210 I 
ATOM 1662 N N   . ASN A 1 211 ? -33.985 -18.335 47.414  1.0 70.33 ? 211 ASN A N   1 Q8R3G1 UNP 211 N 
ATOM 1663 C CA  . ASN A 1 211 ? -35.059 -18.034 48.342  1.0 70.33 ? 211 ASN A CA  1 Q8R3G1 UNP 211 N 
ATOM 1664 C C   . ASN A 1 211 ? -35.008 -16.536 48.694  1.0 70.33 ? 211 ASN A C   1 Q8R3G1 UNP 211 N 
ATOM 1665 C CB  . ASN A 1 211 ? -35.003 -18.938 49.572  1.0 70.33 ? 211 ASN A CB  1 Q8R3G1 UNP 211 N 
ATOM 1666 O O   . ASN A 1 211 ? -33.922 -15.957 48.789  1.0 70.33 ? 211 ASN A O   1 Q8R3G1 UNP 211 N 
ATOM 1667 C CG  . ASN A 1 211 ? -34.901 -20.406 49.246  1.0 70.33 ? 211 ASN A CG  1 Q8R3G1 UNP 211 N 
ATOM 1668 N ND2 . ASN A 1 211 ? -33.772 -21.003 49.537  1.0 70.33 ? 211 ASN A ND2 1 Q8R3G1 UNP 211 N 
ATOM 1669 O OD1 . ASN A 1 211 ? -35.813 -21.007 48.693  1.0 70.33 ? 211 ASN A OD1 1 Q8R3G1 UNP 211 N 
ATOM 1670 N N   . PRO A 1 212 ? -36.154 -15.863 48.882  1.0 67.62 ? 212 PRO A N   1 Q8R3G1 UNP 212 P 
ATOM 1671 C CA  . PRO A 1 212 ? -36.183 -14.441 49.220  1.0 67.62 ? 212 PRO A CA  1 Q8R3G1 UNP 212 P 
ATOM 1672 C C   . PRO A 1 212 ? -35.447 -14.102 50.532  1.0 67.62 ? 212 PRO A C   1 Q8R3G1 UNP 212 P 
ATOM 1673 C CB  . PRO A 1 212 ? -37.670 -14.073 49.259  1.0 67.62 ? 212 PRO A CB  1 Q8R3G1 UNP 212 P 
ATOM 1674 O O   . PRO A 1 212 ? -35.094 -12.944 50.733  1.0 67.62 ? 212 PRO A O   1 Q8R3G1 UNP 212 P 
ATOM 1675 C CG  . PRO A 1 212 ? -38.376 -15.403 49.525  1.0 67.62 ? 212 PRO A CG  1 Q8R3G1 UNP 212 P 
ATOM 1676 C CD  . PRO A 1 212 ? -37.492 -16.420 48.815  1.0 67.62 ? 212 PRO A CD  1 Q8R3G1 UNP 212 P 
ATOM 1677 N N   . GLU A 1 213 ? -35.189 -15.077 51.408  1.0 67.81 ? 213 GLU A N   1 Q8R3G1 UNP 213 E 
ATOM 1678 C CA  . GLU A 1 213 ? -34.336 -14.945 52.595  1.0 67.81 ? 213 GLU A CA  1 Q8R3G1 UNP 213 E 
ATOM 1679 C C   . GLU A 1 213 ? -32.823 -14.953 52.309  1.0 67.81 ? 213 GLU A C   1 Q8R3G1 UNP 213 E 
ATOM 1680 C CB  . GLU A 1 213 ? -34.685 -16.029 53.634  1.0 67.81 ? 213 GLU A CB  1 Q8R3G1 UNP 213 E 
ATOM 1681 O O   . GLU A 1 213 ? -32.063 -14.418 53.115  1.0 67.81 ? 213 GLU A O   1 Q8R3G1 UNP 213 E 
ATOM 1682 C CG  . GLU A 1 213 ? -34.484 -17.492 53.185  1.0 67.81 ? 213 GLU A CG  1 Q8R3G1 UNP 213 E 
ATOM 1683 C CD  . GLU A 1 213 ? -35.743 -18.130 52.579  1.0 67.81 ? 213 GLU A CD  1 Q8R3G1 UNP 213 E 
ATOM 1684 O OE1 . GLU A 1 213 ? -35.917 -19.357 52.744  1.0 67.81 ? 213 GLU A OE1 1 Q8R3G1 UNP 213 E 
ATOM 1685 O OE2 . GLU A 1 213 ? -36.552 -17.396 51.957  1.0 67.81 ? 213 GLU A OE2 1 Q8R3G1 UNP 213 E 
ATOM 1686 N N   . ASP A 1 214 ? -32.386 -15.508 51.173  1.0 67.66 ? 214 ASP A N   1 Q8R3G1 UNP 214 D 
ATOM 1687 C CA  . ASP A 1 214 ? -30.970 -15.594 50.780  1.0 67.66 ? 214 ASP A CA  1 Q8R3G1 UNP 214 D 
ATOM 1688 C C   . ASP A 1 214 ? -30.467 -14.286 50.136  1.0 67.66 ? 214 ASP A C   1 Q8R3G1 UNP 214 D 
ATOM 1689 C CB  . ASP A 1 214 ? -30.756 -16.797 49.839  1.0 67.66 ? 214 ASP A CB  1 Q8R3G1 UNP 214 D 
ATOM 1690 O O   . ASP A 1 214 ? -29.264 -14.086 49.944  1.0 67.66 ? 214 ASP A O   1 Q8R3G1 UNP 214 D 
ATOM 1691 C CG  . ASP A 1 214 ? -31.020 -18.159 50.499  1.0 67.66 ? 214 ASP A CG  1 Q8R3G1 UNP 214 D 
ATOM 1692 O OD1 . ASP A 1 214 ? -30.612 -18.332 51.669  1.0 67.66 ? 214 ASP A OD1 1 Q8R3G1 UNP 214 D 
ATOM 1693 O OD2 . ASP A 1 214 ? -31.599 -19.041 49.817  1.0 67.66 ? 214 ASP A OD2 1 Q8R3G1 UNP 214 D 
ATOM 1694 N N   . VAL A 1 215 ? -31.382 -13.363 49.820  1.0 66.16 ? 215 VAL A N   1 Q8R3G1 UNP 215 V 
ATOM 1695 C CA  . VAL A 1 215 ? -31.074 -12.030 49.293  1.0 66.16 ? 215 VAL A CA  1 Q8R3G1 UNP 215 V 
ATOM 1696 C C   . VAL A 1 215 ? -31.122 -11.020 50.433  1.0 66.16 ? 215 VAL A C   1 Q8R3G1 UNP 215 V 
ATOM 1697 C CB  . VAL A 1 215 ? -32.019 -11.633 48.141  1.0 66.16 ? 215 VAL A CB  1 Q8R3G1 UNP 215 V 
ATOM 1698 O O   . VAL A 1 215 ? -32.184 -10.510 50.785  1.0 66.16 ? 215 VAL A O   1 Q8R3G1 UNP 215 V 
ATOM 1699 C CG1 . VAL A 1 215 ? -31.598 -10.295 47.514  1.0 66.16 ? 215 VAL A CG1 1 Q8R3G1 UNP 215 V 
ATOM 1700 C CG2 . VAL A 1 215 ? -32.007 -12.684 47.029  1.0 66.16 ? 215 VAL A CG2 1 Q8R3G1 UNP 215 V 
ATOM 1701 N N   . ASP A 1 216 ? -29.957 -10.690 50.991  1.0 65.51 ? 216 ASP A N   1 Q8R3G1 UNP 216 D 
ATOM 1702 C CA  . ASP A 1 216 ? -29.843 -9.590  51.949  1.0 65.51 ? 216 ASP A CA  1 Q8R3G1 UNP 216 D 
ATOM 1703 C C   . ASP A 1 216 ? -30.181 -8.258  51.244  1.0 65.51 ? 216 ASP A C   1 Q8R3G1 UNP 216 D 
ATOM 1704 C CB  . ASP A 1 216 ? -28.443 -9.574  52.584  1.0 65.51 ? 216 ASP A CB  1 Q8R3G1 UNP 216 D 
ATOM 1705 O O   . ASP A 1 216 ? -29.425 -7.813  50.371  1.0 65.51 ? 216 ASP A O   1 Q8R3G1 UNP 216 D 
ATOM 1706 C CG  . ASP A 1 216 ? -28.276 -8.518  53.687  1.0 65.51 ? 216 ASP A CG  1 Q8R3G1 UNP 216 D 
ATOM 1707 O OD1 . ASP A 1 216 ? -29.097 -7.572  53.782  1.0 65.51 ? 216 ASP A OD1 1 Q8R3G1 UNP 216 D 
ATOM 1708 O OD2 . ASP A 1 216 ? -27.269 -8.586  54.416  1.0 65.51 ? 216 ASP A OD2 1 Q8R3G1 UNP 216 D 
ATOM 1709 N N   . PRO A 1 217 ? -31.281 -7.571  51.612  1.0 68.37 ? 217 PRO A N   1 Q8R3G1 UNP 217 P 
ATOM 1710 C CA  . PRO A 1 217 ? -31.677 -6.309  50.987  1.0 68.37 ? 217 PRO A CA  1 Q8R3G1 UNP 217 P 
ATOM 1711 C C   . PRO A 1 217 ? -30.659 -5.174  51.209  1.0 68.37 ? 217 PRO A C   1 Q8R3G1 UNP 217 P 
ATOM 1712 C CB  . PRO A 1 217 ? -33.050 -5.989  51.592  1.0 68.37 ? 217 PRO A CB  1 Q8R3G1 UNP 217 P 
ATOM 1713 O O   . PRO A 1 217 ? -30.764 -4.115  50.582  1.0 68.37 ? 217 PRO A O   1 Q8R3G1 UNP 217 P 
ATOM 1714 C CG  . PRO A 1 217 ? -33.015 -6.672  52.959  1.0 68.37 ? 217 PRO A CG  1 Q8R3G1 UNP 217 P 
ATOM 1715 C CD  . PRO A 1 217 ? -32.196 -7.925  52.689  1.0 68.37 ? 217 PRO A CD  1 Q8R3G1 UNP 217 P 
ATOM 1716 N N   . SER A 1 218 ? -29.675 -5.369  52.094  1.0 67.37 ? 218 SER A N   1 Q8R3G1 UNP 218 S 
ATOM 1717 C CA  . SER A 1 218 ? -28.583 -4.432  52.356  1.0 67.37 ? 218 SER A CA  1 Q8R3G1 UNP 218 S 
ATOM 1718 C C   . SER A 1 218 ? -27.340 -4.651  51.478  1.0 67.37 ? 218 SER A C   1 Q8R3G1 UNP 218 S 
ATOM 1719 C CB  . SER A 1 218 ? -28.240 -4.452  53.850  1.0 67.37 ? 218 SER A CB  1 Q8R3G1 UNP 218 S 
ATOM 1720 O O   . SER A 1 218 ? -26.495 -3.750  51.405  1.0 67.37 ? 218 SER A O   1 Q8R3G1 UNP 218 S 
ATOM 1721 O OG  . SER A 1 218 ? -27.426 -5.542  54.214  1.0 67.37 ? 218 SER A OG  1 Q8R3G1 UNP 218 S 
ATOM 1722 N N   . VAL A 1 219 ? -27.242 -5.780  50.760  1.0 64.58 ? 219 VAL A N   1 Q8R3G1 UNP 219 V 
ATOM 1723 C CA  . VAL A 1 219 ? -26.065 -6.169  49.966  1.0 64.58 ? 219 VAL A CA  1 Q8R3G1 UNP 219 V 
ATOM 1724 C C   . VAL A 1 219 ? -26.387 -6.179  48.467  1.0 64.58 ? 219 VAL A C   1 Q8R3G1 UNP 219 V 
ATOM 1725 C CB  . VAL A 1 219 ? -25.502 -7.529  50.439  1.0 64.58 ? 219 VAL A CB  1 Q8R3G1 UNP 219 V 
ATOM 1726 O O   . VAL A 1 219 ? -27.280 -6.873  47.998  1.0 64.58 ? 219 VAL A O   1 Q8R3G1 UNP 219 V 
ATOM 1727 C CG1 . VAL A 1 219 ? -24.236 -7.921  49.658  1.0 64.58 ? 219 VAL A CG1 1 Q8R3G1 UNP 219 V 
ATOM 1728 C CG2 . VAL A 1 219 ? -25.106 -7.488  51.921  1.0 64.58 ? 219 VAL A CG2 1 Q8R3G1 UNP 219 V 
ATOM 1729 N N   . GLY A 1 220 ? -25.612 -5.426  47.679  1.0 67.05 ? 220 GLY A N   1 Q8R3G1 UNP 220 G 
ATOM 1730 C CA  . GLY A 1 220 ? -25.659 -5.469  46.212  1.0 67.05 ? 220 GLY A CA  1 Q8R3G1 UNP 220 G 
ATOM 1731 C C   . GLY A 1 220 ? -26.160 -4.193  45.529  1.0 67.05 ? 220 GLY A C   1 Q8R3G1 UNP 220 G 
ATOM 1732 O O   . GLY A 1 220 ? -26.609 -3.228  46.147  1.0 67.05 ? 220 GLY A O   1 Q8R3G1 UNP 220 G 
ATOM 1733 N N   . ARG A 1 221 ? -26.039 -4.177  44.197  1.0 67.48 ? 221 ARG A N   1 Q8R3G1 UNP 221 R 
ATOM 1734 C CA  . ARG A 1 221 ? -26.284 -3.001  43.338  1.0 67.48 ? 221 ARG A CA  1 Q8R3G1 UNP 221 R 
ATOM 1735 C C   . ARG A 1 221 ? -27.753 -2.563  43.259  1.0 67.48 ? 221 ARG A C   1 Q8R3G1 UNP 221 R 
ATOM 1736 C CB  . ARG A 1 221 ? -25.726 -3.282  41.928  1.0 67.48 ? 221 ARG A CB  1 Q8R3G1 UNP 221 R 
ATOM 1737 O O   . ARG A 1 221 ? -28.022 -1.489  42.736  1.0 67.48 ? 221 ARG A O   1 Q8R3G1 UNP 221 R 
ATOM 1738 C CG  . ARG A 1 221 ? -24.727 -2.210  41.474  1.0 67.48 ? 221 ARG A CG  1 Q8R3G1 UNP 221 R 
ATOM 1739 C CD  . ARG A 1 221 ? -24.297 -2.490  40.030  1.0 67.48 ? 221 ARG A CD  1 Q8R3G1 UNP 221 R 
ATOM 1740 N NE  . ARG A 1 221 ? -23.223 -1.580  39.586  1.0 67.48 ? 221 ARG A NE  1 Q8R3G1 UNP 221 R 
ATOM 1741 N NH1 . ARG A 1 221 ? -22.882 -2.538  37.525  1.0 67.48 ? 221 ARG A NH1 1 Q8R3G1 UNP 221 R 
ATOM 1742 N NH2 . ARG A 1 221 ? -21.637 -0.796  38.147  1.0 67.48 ? 221 ARG A NH2 1 Q8R3G1 UNP 221 R 
ATOM 1743 C CZ  . ARG A 1 221 ? -22.589 -1.641  38.426  1.0 67.48 ? 221 ARG A CZ  1 Q8R3G1 UNP 221 R 
ATOM 1744 N N   . PHE A 1 222 ? -28.671 -3.382  43.770  1.0 61.92 ? 222 PHE A N   1 Q8R3G1 UNP 222 F 
ATOM 1745 C CA  . PHE A 1 222 ? -30.121 -3.177  43.708  1.0 61.92 ? 222 PHE A CA  1 Q8R3G1 UNP 222 F 
ATOM 1746 C C   . PHE A 1 222 ? -30.723 -2.697  45.034  1.0 61.92 ? 222 PHE A C   1 Q8R3G1 UNP 222 F 
ATOM 1747 C CB  . PHE A 1 222 ? -30.789 -4.453  43.184  1.0 61.92 ? 222 PHE A CB  1 Q8R3G1 UNP 222 F 
ATOM 1748 O O   . PHE A 1 222 ? -31.941 -2.743  45.215  1.0 61.92 ? 222 PHE A O   1 Q8R3G1 UNP 222 F 
ATOM 1749 C CG  . PHE A 1 222 ? -30.264 -4.885  41.830  1.0 61.92 ? 222 PHE A CG  1 Q8R3G1 UNP 222 F 
ATOM 1750 C CD1 . PHE A 1 222 ? -30.621 -4.159  40.678  1.0 61.92 ? 222 PHE A CD1 1 Q8R3G1 UNP 222 F 
ATOM 1751 C CD2 . PHE A 1 222 ? -29.412 -6.000  41.721  1.0 61.92 ? 222 PHE A CD2 1 Q8R3G1 UNP 222 F 
ATOM 1752 C CE1 . PHE A 1 222 ? -30.134 -4.552  39.420  1.0 61.92 ? 222 PHE A CE1 1 Q8R3G1 UNP 222 F 
ATOM 1753 C CE2 . PHE A 1 222 ? -28.923 -6.391  40.463  1.0 61.92 ? 222 PHE A CE2 1 Q8R3G1 UNP 222 F 
ATOM 1754 C CZ  . PHE A 1 222 ? -29.287 -5.669  39.312  1.0 61.92 ? 222 PHE A CZ  1 Q8R3G1 UNP 222 F 
ATOM 1755 N N   . ARG A 1 223 ? -29.885 -2.202  45.958  1.0 58.68 ? 223 ARG A N   1 Q8R3G1 UNP 223 R 
ATOM 1756 C CA  . ARG A 1 223 ? -30.347 -1.490  47.155  1.0 58.68 ? 223 ARG A CA  1 Q8R3G1 UNP 223 R 
ATOM 1757 C C   . ARG A 1 223 ? -31.348 -0.410  46.723  1.0 58.68 ? 223 ARG A C   1 Q8R3G1 UNP 223 R 
ATOM 1758 C CB  . ARG A 1 223 ? -29.131 -0.908  47.905  1.0 58.68 ? 223 ARG A CB  1 Q8R3G1 UNP 223 R 
ATOM 1759 O O   . ARG A 1 223 ? -30.988 0.467   45.943  1.0 58.68 ? 223 ARG A O   1 Q8R3G1 UNP 223 R 
ATOM 1760 C CG  . ARG A 1 223 ? -29.528 -0.356  49.283  1.0 58.68 ? 223 ARG A CG  1 Q8R3G1 UNP 223 R 
ATOM 1761 C CD  . ARG A 1 223 ? -28.320 0.079   50.125  1.0 58.68 ? 223 ARG A CD  1 Q8R3G1 UNP 223 R 
ATOM 1762 N NE  . ARG A 1 223 ? -27.916 1.481   49.881  1.0 58.68 ? 223 ARG A NE  1 Q8R3G1 UNP 223 R 
ATOM 1763 N NH1 . ARG A 1 223 ? -26.314 1.572   51.522  1.0 58.68 ? 223 ARG A NH1 1 Q8R3G1 UNP 223 R 
ATOM 1764 N NH2 . ARG A 1 223 ? -26.817 3.423   50.380  1.0 58.68 ? 223 ARG A NH2 1 Q8R3G1 UNP 223 R 
ATOM 1765 C CZ  . ARG A 1 223 ? -27.021 2.151   50.590  1.0 58.68 ? 223 ARG A CZ  1 Q8R3G1 UNP 223 R 
ATOM 1766 N N   . ASN A 1 224 ? -32.578 -0.480  47.237  1.0 61.46 ? 224 ASN A N   1 Q8R3G1 UNP 224 N 
ATOM 1767 C CA  . ASN A 1 224 ? -33.736 0.383   46.926  1.0 61.46 ? 224 ASN A CA  1 Q8R3G1 UNP 224 N 
ATOM 1768 C C   . ASN A 1 224 ? -34.606 0.002   45.708  1.0 61.46 ? 224 ASN A C   1 Q8R3G1 UNP 224 N 
ATOM 1769 C CB  . ASN A 1 224 ? -33.355 1.878   46.890  1.0 61.46 ? 224 ASN A CB  1 Q8R3G1 UNP 224 N 
ATOM 1770 O O   . ASN A 1 224 ? -35.541 0.740   45.406  1.0 61.46 ? 224 ASN A O   1 Q8R3G1 UNP 224 N 
ATOM 1771 C CG  . ASN A 1 224 ? -32.445 2.323   48.016  1.0 61.46 ? 224 ASN A CG  1 Q8R3G1 UNP 224 N 
ATOM 1772 N ND2 . ASN A 1 224 ? -31.475 3.159   47.730  1.0 61.46 ? 224 ASN A ND2 1 Q8R3G1 UNP 224 N 
ATOM 1773 O OD1 . ASN A 1 224 ? -32.580 1.945   49.165  1.0 61.46 ? 224 ASN A OD1 1 Q8R3G1 UNP 224 N 
ATOM 1774 N N   . MET A 1 225 ? -34.359 -1.125  45.033  1.0 64.94 ? 225 MET A N   1 Q8R3G1 UNP 225 M 
ATOM 1775 C CA  . MET A 1 225 ? -35.214 -1.609  43.930  1.0 64.94 ? 225 MET A CA  1 Q8R3G1 UNP 225 M 
ATOM 1776 C C   . MET A 1 225 ? -36.068 -2.838  44.278  1.0 64.94 ? 225 MET A C   1 Q8R3G1 UNP 225 M 
ATOM 1777 C CB  . MET A 1 225 ? -34.370 -1.862  42.673  1.0 64.94 ? 225 MET A CB  1 Q8R3G1 UNP 225 M 
ATOM 1778 O O   . MET A 1 225 ? -36.880 -3.260  43.459  1.0 64.94 ? 225 MET A O   1 Q8R3G1 UNP 225 M 
ATOM 1779 C CG  . MET A 1 225 ? -34.054 -0.557  41.936  1.0 64.94 ? 225 MET A CG  1 Q8R3G1 UNP 225 M 
ATOM 1780 S SD  . MET A 1 225 ? -33.102 -0.773  40.406  1.0 64.94 ? 225 MET A SD  1 Q8R3G1 UNP 225 M 
ATOM 1781 C CE  . MET A 1 225 ? -34.273 -1.730  39.398  1.0 64.94 ? 225 MET A CE  1 Q8R3G1 UNP 225 M 
ATOM 1782 N N   . VAL A 1 226 ? -35.926 -3.405  45.477  1.0 63.72 ? 226 VAL A N   1 Q8R3G1 UNP 226 V 
ATOM 1783 C CA  . VAL A 1 226 ? -36.694 -4.585  45.904  1.0 63.72 ? 226 VAL A CA  1 Q8R3G1 UNP 226 V 
ATOM 1784 C C   . VAL A 1 226 ? -37.853 -4.150  46.805  1.0 63.72 ? 226 VAL A C   1 Q8R3G1 UNP 226 V 
ATOM 1785 C CB  . VAL A 1 226 ? -35.780 -5.633  46.573  1.0 63.72 ? 226 VAL A CB  1 Q8R3G1 UNP 226 V 
ATOM 1786 O O   . VAL A 1 226 ? -37.633 -3.622  47.894  1.0 63.72 ? 226 VAL A O   1 Q8R3G1 UNP 226 V 
ATOM 1787 C CG1 . VAL A 1 226 ? -36.558 -6.913  46.896  1.0 63.72 ? 226 VAL A CG1 1 Q8R3G1 UNP 226 V 
ATOM 1788 C CG2 . VAL A 1 226 ? -34.604 -6.014  45.659  1.0 63.72 ? 226 VAL A CG2 1 Q8R3G1 UNP 226 V 
ATOM 1789 N N   . GLN A 1 227 ? -39.091 -4.370  46.352  1.0 67.78 ? 227 GLN A N   1 Q8R3G1 UNP 227 Q 
ATOM 1790 C CA  . GLN A 1 227 ? -40.302 -4.297  47.175  1.0 67.78 ? 227 GLN A CA  1 Q8R3G1 UNP 227 Q 
ATOM 1791 C C   . GLN A 1 227 ? -40.797 -5.720  47.457  1.0 67.78 ? 227 GLN A C   1 Q8R3G1 UNP 227 Q 
ATOM 1792 C CB  . GLN A 1 227 ? -41.406 -3.479  46.476  1.0 67.78 ? 227 GLN A CB  1 Q8R3G1 UNP 227 Q 
ATOM 1793 O O   . GLN A 1 227 ? -41.138 -6.450  46.530  1.0 67.78 ? 227 GLN A O   1 Q8R3G1 UNP 227 Q 
ATOM 1794 C CG  . GLN A 1 227 ? -41.205 -1.961  46.586  1.0 67.78 ? 227 GLN A CG  1 Q8R3G1 UNP 227 Q 
ATOM 1795 C CD  . GLN A 1 227 ? -42.341 -1.160  45.946  1.0 67.78 ? 227 GLN A CD  1 Q8R3G1 UNP 227 Q 
ATOM 1796 N NE2 . GLN A 1 227 ? -42.400 0.134   46.168  1.0 67.78 ? 227 GLN A NE2 1 Q8R3G1 UNP 227 Q 
ATOM 1797 O OE1 . GLN A 1 227 ? -43.198 -1.661  45.240  1.0 67.78 ? 227 GLN A OE1 1 Q8R3G1 UNP 227 Q 
ATOM 1798 N N   . THR A 1 228 ? -40.873 -6.101  48.732  1.0 70.50 ? 228 THR A N   1 Q8R3G1 UNP 228 T 
ATOM 1799 C CA  . THR A 1 228 ? -41.437 -7.390  49.160  1.0 70.50 ? 228 THR A CA  1 Q8R3G1 UNP 228 T 
ATOM 1800 C C   . THR A 1 228 ? -42.854 -7.172  49.688  1.0 70.50 ? 228 THR A C   1 Q8R3G1 UNP 228 T 
ATOM 1801 C CB  . THR A 1 228 ? -40.545 -8.068  50.215  1.0 70.50 ? 228 THR A CB  1 Q8R3G1 UNP 228 T 
ATOM 1802 O O   . THR A 1 228 ? -43.043 -6.462  50.674  1.0 70.50 ? 228 THR A O   1 Q8R3G1 UNP 228 T 
ATOM 1803 C CG2 . THR A 1 228 ? -41.017 -9.482  50.557  1.0 70.50 ? 228 THR A CG2 1 Q8R3G1 UNP 228 T 
ATOM 1804 O OG1 . THR A 1 228 ? -39.236 -8.182  49.710  1.0 70.50 ? 228 THR A OG1 1 Q8R3G1 UNP 228 T 
ATOM 1805 N N   . ALA A 1 229 ? -43.855 -7.792  49.057  1.0 74.39 ? 229 ALA A N   1 Q8R3G1 UNP 229 A 
ATOM 1806 C CA  . ALA A 1 229 ? -45.237 -7.818  49.537  1.0 74.39 ? 229 ALA A CA  1 Q8R3G1 UNP 229 A 
ATOM 1807 C C   . ALA A 1 229 ? -45.600 -9.237  50.005  1.0 74.39 ? 229 ALA A C   1 Q8R3G1 UNP 229 A 
ATOM 1808 C CB  . ALA A 1 229 ? -46.169 -7.299  48.433  1.0 74.39 ? 229 ALA A CB  1 Q8R3G1 UNP 229 A 
ATOM 1809 O O   . ALA A 1 229 ? -45.591 -10.181 49.219  1.0 74.39 ? 229 ALA A O   1 Q8R3G1 UNP 229 A 
ATOM 1810 N N   . VAL A 1 230 ? -45.919 -9.395  51.293  1.0 75.92 ? 230 VAL A N   1 Q8R3G1 UNP 230 V 
ATOM 1811 C CA  . VAL A 1 230 ? -46.336 -10.680 51.877  1.0 75.92 ? 230 VAL A CA  1 Q8R3G1 UNP 230 V 
ATOM 1812 C C   . VAL A 1 230 ? -47.842 -10.848 51.686  1.0 75.92 ? 230 VAL A C   1 Q8R3G1 UNP 230 V 
ATOM 1813 C CB  . VAL A 1 230 ? -45.940 -10.775 53.367  1.0 75.92 ? 230 VAL A CB  1 Q8R3G1 UNP 230 V 
ATOM 1814 O O   . VAL A 1 230 ? -48.630 -10.118 52.285  1.0 75.92 ? 230 VAL A O   1 Q8R3G1 UNP 230 V 
ATOM 1815 C CG1 . VAL A 1 230 ? -46.401 -12.097 54.000  1.0 75.92 ? 230 VAL A CG1 1 Q8R3G1 UNP 230 V 
ATOM 1816 C CG2 . VAL A 1 230 ? -44.418 -10.679 53.536  1.0 75.92 ? 230 VAL A CG2 1 Q8R3G1 UNP 230 V 
ATOM 1817 N N   . VAL A 1 231 ? -48.255 -11.824 50.874  1.0 69.00 ? 231 VAL A N   1 Q8R3G1 UNP 231 V 
ATOM 1818 C CA  . VAL A 1 231 ? -49.667 -12.213 50.740  1.0 69.00 ? 231 VAL A CA  1 Q8R3G1 UNP 231 V 
ATOM 1819 C C   . VAL A 1 231 ? -49.986 -13.285 51.789  1.0 69.00 ? 231 VAL A C   1 Q8R3G1 UNP 231 V 
ATOM 1820 C CB  . VAL A 1 231 ? -50.003 -12.702 49.317  1.0 69.00 ? 231 VAL A CB  1 Q8R3G1 UNP 231 V 
ATOM 1821 O O   . VAL A 1 231 ? -49.470 -14.400 51.695  1.0 69.00 ? 231 VAL A O   1 Q8R3G1 UNP 231 V 
ATOM 1822 C CG1 . VAL A 1 231 ? -51.492 -13.063 49.198  1.0 69.00 ? 231 VAL A CG1 1 Q8R3G1 UNP 231 V 
ATOM 1823 C CG2 . VAL A 1 231 ? -49.701 -11.616 48.277  1.0 69.00 ? 231 VAL A CG2 1 Q8R3G1 UNP 231 V 
ATOM 1824 N N   . PRO A 1 232 ? -50.833 -13.007 52.797  1.0 73.70 ? 232 PRO A N   1 Q8R3G1 UNP 232 P 
ATOM 1825 C CA  . PRO A 1 232 ? -51.215 -14.013 53.777  1.0 73.70 ? 232 PRO A CA  1 Q8R3G1 UNP 232 P 
ATOM 1826 C C   . PRO A 1 232 ? -52.107 -15.077 53.124  1.0 73.70 ? 232 PRO A C   1 Q8R3G1 UNP 232 P 
ATOM 1827 C CB  . PRO A 1 232 ? -51.905 -13.245 54.909  1.0 73.70 ? 232 PRO A CB  1 Q8R3G1 UNP 232 P 
ATOM 1828 O O   . PRO A 1 232 ? -53.282 -14.845 52.835  1.0 73.70 ? 232 PRO A O   1 Q8R3G1 UNP 232 P 
ATOM 1829 C CG  . PRO A 1 232 ? -52.444 -11.988 54.226  1.0 73.70 ? 232 PRO A CG  1 Q8R3G1 UNP 232 P 
ATOM 1830 C CD  . PRO A 1 232 ? -51.437 -11.721 53.112  1.0 73.70 ? 232 PRO A CD  1 Q8R3G1 UNP 232 P 
ATOM 1831 N N   . VAL A 1 233 ? -51.569 -16.283 52.939  1.0 69.71 ? 233 VAL A N   1 Q8R3G1 UNP 233 V 
ATOM 1832 C CA  . VAL A 1 233 ? -52.361 -17.473 52.598  1.0 69.71 ? 233 VAL A CA  1 Q8R3G1 UNP 233 V 
ATOM 1833 C C   . VAL A 1 233 ? -53.206 -17.865 53.811  1.0 69.71 ? 233 VAL A C   1 Q8R3G1 UNP 233 V 
ATOM 1834 C CB  . VAL A 1 233 ? -51.511 -18.657 52.066  1.0 69.71 ? 233 VAL A CB  1 Q8R3G1 UNP 233 V 
ATOM 1835 O O   . VAL A 1 233 ? -52.772 -18.584 54.711  1.0 69.71 ? 233 VAL A O   1 Q8R3G1 UNP 233 V 
ATOM 1836 C CG1 . VAL A 1 233 ? -51.724 -18.821 50.558  1.0 69.71 ? 233 VAL A CG1 1 Q8R3G1 UNP 233 V 
ATOM 1837 C CG2 . VAL A 1 233 ? -50.005 -18.535 52.336  1.0 69.71 ? 233 VAL A CG2 1 Q8R3G1 UNP 233 V 
ATOM 1838 N N   . LYS A 1 234 ? -54.449 -17.374 53.854  1.0 62.48 ? 234 LYS A N   1 Q8R3G1 UNP 234 K 
ATOM 1839 C CA  . LYS A 1 234 ? -55.464 -17.860 54.793  1.0 62.48 ? 234 LYS A CA  1 Q8R3G1 UNP 234 K 
ATOM 1840 C C   . LYS A 1 234 ? -55.718 -19.345 54.520  1.0 62.48 ? 234 LYS A C   1 Q8R3G1 UNP 234 K 
ATOM 1841 C CB  . LYS A 1 234 ? -56.759 -17.031 54.688  1.0 62.48 ? 234 LYS A CB  1 Q8R3G1 UNP 234 K 
ATOM 1842 O O   . LYS A 1 234 ? -56.341 -19.707 53.524  1.0 62.48 ? 234 LYS A O   1 Q8R3G1 UNP 234 K 
ATOM 1843 C CG  . LYS A 1 234 ? -56.688 -15.728 55.502  1.0 62.48 ? 234 LYS A CG  1 Q8R3G1 UNP 234 K 
ATOM 1844 C CD  . LYS A 1 234 ? -58.014 -14.951 55.439  1.0 62.48 ? 234 LYS A CD  1 Q8R3G1 UNP 234 K 
ATOM 1845 C CE  . LYS A 1 234 ? -58.021 -13.816 56.474  1.0 62.48 ? 234 LYS A CE  1 Q8R3G1 UNP 234 K 
ATOM 1846 N NZ  . LYS A 1 234 ? -59.235 -12.964 56.368  1.0 62.48 ? 234 LYS A NZ  1 Q8R3G1 UNP 234 K 
ATOM 1847 N N   . LYS A 1 235 ? -55.275 -20.207 55.443  1.0 58.87 ? 235 LYS A N   1 Q8R3G1 UNP 235 K 
ATOM 1848 C CA  . LYS A 1 235 ? -55.737 -21.597 55.555  1.0 58.87 ? 235 LYS A CA  1 Q8R3G1 UNP 235 K 
ATOM 1849 C C   . LYS A 1 235 ? -57.261 -21.589 55.689  1.0 58.87 ? 235 LYS A C   1 Q8R3G1 UNP 235 K 
ATOM 1850 C CB  . LYS A 1 235 ? -55.085 -22.293 56.769  1.0 58.87 ? 235 LYS A CB  1 Q8R3G1 UNP 235 K 
ATOM 1851 O O   . LYS A 1 235 ? -57.796 -21.254 56.743  1.0 58.87 ? 235 LYS A O   1 Q8R3G1 UNP 235 K 
ATOM 1852 C CG  . LYS A 1 235 ? -53.720 -22.914 56.436  1.0 58.87 ? 235 LYS A CG  1 Q8R3G1 UNP 235 K 
ATOM 1853 C CD  . LYS A 1 235 ? -53.094 -23.598 57.665  1.0 58.87 ? 235 LYS A CD  1 Q8R3G1 UNP 235 K 
ATOM 1854 C CE  . LYS A 1 235 ? -51.888 -24.446 57.233  1.0 58.87 ? 235 LYS A CE  1 Q8R3G1 UNP 235 K 
ATOM 1855 N NZ  . LYS A 1 235 ? -51.104 -24.958 58.387  1.0 58.87 ? 235 LYS A NZ  1 Q8R3G1 UNP 235 K 
ATOM 1856 N N   . LYS A 1 236 ? -57.960 -21.972 54.621  1.0 50.26 ? 236 LYS A N   1 Q8R3G1 UNP 236 K 
ATOM 1857 C CA  . LYS A 1 236 ? -59.399 -22.241 54.636  1.0 50.26 ? 236 LYS A CA  1 Q8R3G1 UNP 236 K 
ATOM 1858 C C   . LYS A 1 236 ? -59.639 -23.543 55.409  1.0 50.26 ? 236 LYS A C   1 Q8R3G1 UNP 236 K 
ATOM 1859 C CB  . LYS A 1 236 ? -59.922 -22.250 53.186  1.0 50.26 ? 236 LYS A CB  1 Q8R3G1 UNP 236 K 
ATOM 1860 O O   . LYS A 1 236 ? -59.687 -24.621 54.826  1.0 50.26 ? 236 LYS A O   1 Q8R3G1 UNP 236 K 
ATOM 1861 C CG  . LYS A 1 236 ? -61.455 -22.348 53.095  1.0 50.26 ? 236 LYS A CG  1 Q8R3G1 UNP 236 K 
ATOM 1862 C CD  . LYS A 1 236 ? -61.910 -22.367 51.627  1.0 50.26 ? 236 LYS A CD  1 Q8R3G1 UNP 236 K 
ATOM 1863 C CE  . LYS A 1 236 ? -63.428 -22.571 51.531  1.0 50.26 ? 236 LYS A CE  1 Q8R3G1 UNP 236 K 
ATOM 1864 N NZ  . LYS A 1 236 ? -63.892 -22.620 50.120  1.0 50.26 ? 236 LYS A NZ  1 Q8R3G1 UNP 236 K 
ATOM 1865 N N   . ARG A 1 237 ? -59.752 -23.437 56.738  1.0 46.26 ? 237 ARG A N   1 Q8R3G1 UNP 237 R 
ATOM 1866 C CA  . ARG A 1 237 ? -60.457 -24.427 57.561  1.0 46.26 ? 237 ARG A CA  1 Q8R3G1 UNP 237 R 
ATOM 1867 C C   . ARG A 1 237 ? -61.950 -24.232 57.296  1.0 46.26 ? 237 ARG A C   1 Q8R3G1 UNP 237 R 
ATOM 1868 C CB  . ARG A 1 237 ? -60.114 -24.278 59.058  1.0 46.26 ? 237 ARG A CB  1 Q8R3G1 UNP 237 R 
ATOM 1869 O O   . ARG A 1 237 ? -62.452 -23.114 57.349  1.0 46.26 ? 237 ARG A O   1 Q8R3G1 UNP 237 R 
ATOM 1870 C CG  . ARG A 1 237 ? -59.613 -25.595 59.676  1.0 46.26 ? 237 ARG A CG  1 Q8R3G1 UNP 237 R 
ATOM 1871 C CD  . ARG A 1 237 ? -59.524 -25.470 61.203  1.0 46.26 ? 237 ARG A CD  1 Q8R3G1 UNP 237 R 
ATOM 1872 N NE  . ARG A 1 237 ? -58.724 -26.556 61.808  1.0 46.26 ? 237 ARG A NE  1 Q8R3G1 UNP 237 R 
ATOM 1873 N NH1 . ARG A 1 237 ? -59.632 -26.464 63.922  1.0 46.26 ? 237 ARG A NH1 1 Q8R3G1 UNP 237 R 
ATOM 1874 N NH2 . ARG A 1 237 ? -57.931 -27.846 63.514  1.0 46.26 ? 237 ARG A NH2 1 Q8R3G1 UNP 237 R 
ATOM 1875 C CZ  . ARG A 1 237 ? -58.768 -26.947 63.073  1.0 46.26 ? 237 ARG A CZ  1 Q8R3G1 UNP 237 R 
ATOM 1876 N N   . MET A 1 238 ? -62.608 -25.316 56.920  1.0 46.37 ? 238 MET A N   1 Q8R3G1 UNP 238 M 
ATOM 1877 C CA  . MET A 1 238 ? -64.027 -25.375 56.606  1.0 46.37 ? 238 MET A CA  1 Q8R3G1 UNP 238 M 
ATOM 1878 C C   . MET A 1 238 ? -64.827 -25.368 57.912  1.0 46.37 ? 238 MET A C   1 Q8R3G1 UNP 238 M 
ATOM 1879 C CB  . MET A 1 238 ? -64.225 -26.653 55.767  1.0 46.37 ? 238 MET A CB  1 Q8R3G1 UNP 238 M 
ATOM 1880 O O   . MET A 1 238 ? -64.825 -26.363 58.622  1.0 46.37 ? 238 MET A O   1 Q8R3G1 UNP 238 M 
ATOM 1881 C CG  . MET A 1 238 ? -65.624 -26.829 55.178  1.0 46.37 ? 238 MET A CG  1 Q8R3G1 UNP 238 M 
ATOM 1882 S SD  . MET A 1 238 ? -65.632 -27.807 53.644  1.0 46.37 ? 238 MET A SD  1 Q8R3G1 UNP 238 M 
ATOM 1883 C CE  . MET A 1 238 ? -65.381 -29.488 54.281  1.0 46.37 ? 238 MET A CE  1 Q8R3G1 UNP 238 M 
ATOM 1884 N N   . GLU A 1 239 ? -65.492 -24.259 58.220  1.0 44.13 ? 239 GLU A N   1 Q8R3G1 UNP 239 E 
ATOM 1885 C CA  . GLU A 1 239 ? -66.624 -24.204 59.149  1.0 44.13 ? 239 GLU A CA  1 Q8R3G1 UNP 239 E 
ATOM 1886 C C   . GLU A 1 239 ? -67.626 -23.186 58.596  1.0 44.13 ? 239 GLU A C   1 Q8R3G1 UNP 239 E 
ATOM 1887 C CB  . GLU A 1 239 ? -66.185 -23.915 60.598  1.0 44.13 ? 239 GLU A CB  1 Q8R3G1 UNP 239 E 
ATOM 1888 O O   . GLU A 1 239 ? -67.251 -22.113 58.120  1.0 44.13 ? 239 GLU A O   1 Q8R3G1 UNP 239 E 
ATOM 1889 C CG  . GLU A 1 239 ? -66.535 -25.116 61.498  1.0 44.13 ? 239 GLU A CG  1 Q8R3G1 UNP 239 E 
ATOM 1890 C CD  . GLU A 1 239 ? -66.003 -25.009 62.935  1.0 44.13 ? 239 GLU A CD  1 Q8R3G1 UNP 239 E 
ATOM 1891 O OE1 . GLU A 1 239 ? -66.334 -25.918 63.728  1.0 44.13 ? 239 GLU A OE1 1 Q8R3G1 UNP 239 E 
ATOM 1892 O OE2 . GLU A 1 239 ? -65.217 -24.076 63.219  1.0 44.13 ? 239 GLU A OE2 1 Q8R3G1 UNP 239 E 
ATOM 1893 N N   . GLY A 1 240 ? -68.881 -23.618 58.497  1.0 39.35 ? 240 GLY A N   1 Q8R3G1 UNP 240 G 
ATOM 1894 C CA  . GLY A 1 240 ? -69.933 -22.946 57.747  1.0 39.35 ? 240 GLY A CA  1 Q8R3G1 UNP 240 G 
ATOM 1895 C C   . GLY A 1 240 ? -70.627 -21.811 58.497  1.0 39.35 ? 240 GLY A C   1 Q8R3G1 UNP 240 G 
ATOM 1896 O O   . GLY A 1 240 ? -70.510 -21.672 59.710  1.0 39.35 ? 240 GLY A O   1 Q8R3G1 UNP 240 G 
ATOM 1897 N N   . SER A 1 241 ? -71.437 -21.086 57.719  1.0 39.11 ? 241 SER A N   1 Q8R3G1 UNP 241 S 
ATOM 1898 C CA  . SER A 1 241 ? -72.395 -20.028 58.089  1.0 39.11 ? 241 SER A CA  1 Q8R3G1 UNP 241 S 
ATOM 1899 C C   . SER A 1 241 ? -71.745 -18.732 58.580  1.0 39.11 ? 241 SER A C   1 Q8R3G1 UNP 241 S 
ATOM 1900 C CB  . SER A 1 241 ? -73.484 -20.577 59.021  1.0 39.11 ? 241 SER A CB  1 Q8R3G1 UNP 241 S 
ATOM 1901 O O   . SER A 1 241 ? -71.254 -18.634 59.692  1.0 39.11 ? 241 SER A O   1 Q8R3G1 UNP 241 S 
ATOM 1902 O OG  . SER A 1 241 ? -73.025 -20.890 60.316  1.0 39.11 ? 241 SER A OG  1 Q8R3G1 UNP 241 S 
ATOM 1903 N N   . GLY A 1 242 ? -71.562 -17.739 57.712  1.0 37.48 ? 242 GLY A N   1 Q8R3G1 UNP 242 G 
ATOM 1904 C CA  . GLY A 1 242 ? -72.569 -16.766 57.255  1.0 37.48 ? 242 GLY A CA  1 Q8R3G1 UNP 242 G 
ATOM 1905 C C   . GLY A 1 242 ? -71.906 -15.391 57.474  1.0 37.48 ? 242 GLY A C   1 Q8R3G1 UNP 242 G 
ATOM 1906 O O   . GLY A 1 242 ? -71.086 -15.262 58.369  1.0 37.48 ? 242 GLY A O   1 Q8R3G1 UNP 242 G 
ATOM 1907 N N   . SER A 1 243 ? -72.094 -14.315 56.726  1.0 39.32 ? 243 SER A N   1 Q8R3G1 UNP 243 S 
ATOM 1908 C CA  . SER A 1 243 ? -73.128 -13.879 55.807  1.0 39.32 ? 243 SER A CA  1 Q8R3G1 UNP 243 S 
ATOM 1909 C C   . SER A 1 243 ? -72.612 -12.556 55.186  1.0 39.32 ? 243 SER A C   1 Q8R3G1 UNP 243 S 
ATOM 1910 C CB  . SER A 1 243 ? -74.368 -13.596 56.670  1.0 39.32 ? 243 SER A CB  1 Q8R3G1 UNP 243 S 
ATOM 1911 O O   . SER A 1 243 ? -71.889 -11.837 55.874  1.0 39.32 ? 243 SER A O   1 Q8R3G1 UNP 243 S 
ATOM 1912 O OG  . SER A 1 243 ? -75.508 -13.393 55.876  1.0 39.32 ? 243 SER A OG  1 Q8R3G1 UNP 243 S 
ATOM 1913 N N   . LEU A 1 244 ? -73.057 -12.222 53.963  1.0 45.53 ? 244 LEU A N   1 Q8R3G1 UNP 244 L 
ATOM 1914 C CA  . LEU A 1 244 ? -73.041 -10.886 53.304  1.0 45.53 ? 244 LEU A CA  1 Q8R3G1 UNP 244 L 
ATOM 1915 C C   . LEU A 1 244 ? -71.658 -10.398 52.803  1.0 45.53 ? 244 LEU A C   1 Q8R3G1 UNP 244 L 
ATOM 1916 C CB  . LEU A 1 244 ? -73.752 -9.852  54.212  1.0 45.53 ? 244 LEU A CB  1 Q8R3G1 UNP 244 L 
ATOM 1917 O O   . LEU A 1 244 ? -70.726 -10.268 53.583  1.0 45.53 ? 244 LEU A O   1 Q8R3G1 UNP 244 L 
ATOM 1918 C CG  . LEU A 1 244 ? -75.028 -10.348 54.924  1.0 45.53 ? 244 LEU A CG  1 Q8R3G1 UNP 244 L 
ATOM 1919 C CD1 . LEU A 1 244 ? -75.661 -9.266  55.788  1.0 45.53 ? 244 LEU A CD1 1 Q8R3G1 UNP 244 L 
ATOM 1920 C CD2 . LEU A 1 244 ? -76.082 -10.884 53.947  1.0 45.53 ? 244 LEU A CD2 1 Q8R3G1 UNP 244 L 
ATOM 1921 N N   . GLY A 1 245 ? -71.399 -10.218 51.500  1.0 36.94 ? 245 GLY A N   1 Q8R3G1 UNP 245 G 
ATOM 1922 C CA  . GLY A 1 245 ? -72.002 -9.260  50.548  1.0 36.94 ? 245 GLY A CA  1 Q8R3G1 UNP 245 G 
ATOM 1923 C C   . GLY A 1 245 ? -70.922 -8.192  50.273  1.0 36.94 ? 245 GLY A C   1 Q8R3G1 UNP 245 G 
ATOM 1924 O O   . GLY A 1 245 ? -70.404 -7.631  51.226  1.0 36.94 ? 245 GLY A O   1 Q8R3G1 UNP 245 G 
ATOM 1925 N N   . LEU A 1 246 ? -70.392 -7.974  49.065  1.0 44.89 ? 246 LEU A N   1 Q8R3G1 UNP 246 L 
ATOM 1926 C CA  . LEU A 1 246 ? -70.978 -7.205  47.959  1.0 44.89 ? 246 LEU A CA  1 Q8R3G1 UNP 246 L 
ATOM 1927 C C   . LEU A 1 246 ? -69.854 -7.022  46.895  1.0 44.89 ? 246 LEU A C   1 Q8R3G1 UNP 246 L 
ATOM 1928 C CB  . LEU A 1 246 ? -71.373 -5.824  48.551  1.0 44.89 ? 246 LEU A CB  1 Q8R3G1 UNP 246 L 
ATOM 1929 O O   . LEU A 1 246 ? -68.737 -6.722  47.304  1.0 44.89 ? 246 LEU A O   1 Q8R3G1 UNP 246 L 
ATOM 1930 C CG  . LEU A 1 246 ? -72.014 -4.794  47.609  1.0 44.89 ? 246 LEU A CG  1 Q8R3G1 UNP 246 L 
ATOM 1931 C CD1 . LEU A 1 246 ? -73.461 -5.163  47.276  1.0 44.89 ? 246 LEU A CD1 1 Q8R3G1 UNP 246 L 
ATOM 1932 C CD2 . LEU A 1 246 ? -72.056 -3.424  48.291  1.0 44.89 ? 246 LEU A CD2 1 Q8R3G1 UNP 246 L 
ATOM 1933 N N   . GLU A 1 247 ? -70.170 -7.270  45.611  1.0 42.94 ? 247 GLU A N   1 Q8R3G1 UNP 247 E 
ATOM 1934 C CA  . GLU A 1 247 ? -69.725 -6.644  44.329  1.0 42.94 ? 247 GLU A CA  1 Q8R3G1 UNP 247 E 
ATOM 1935 C C   . GLU A 1 247 ? -68.255 -6.131  44.208  1.0 42.94 ? 247 GLU A C   1 Q8R3G1 UNP 247 E 
ATOM 1936 C CB  . GLU A 1 247 ? -70.738 -5.529  43.982  1.0 42.94 ? 247 GLU A CB  1 Q8R3G1 UNP 247 E 
ATOM 1937 O O   . GLU A 1 247 ? -67.726 -5.485  45.096  1.0 42.94 ? 247 GLU A O   1 Q8R3G1 UNP 247 E 
ATOM 1938 C CG  . GLU A 1 247 ? -72.237 -5.838  44.208  1.0 42.94 ? 247 GLU A CG  1 Q8R3G1 UNP 247 E 
ATOM 1939 C CD  . GLU A 1 247 ? -72.906 -6.585  43.057  1.0 42.94 ? 247 GLU A CD  1 Q8R3G1 UNP 247 E 
ATOM 1940 O OE1 . GLU A 1 247 ? -72.946 -7.835  43.132  1.0 42.94 ? 247 GLU A OE1 1 Q8R3G1 UNP 247 E 
ATOM 1941 O OE2 . GLU A 1 247 ? -73.397 -5.903  42.135  1.0 42.94 ? 247 GLU A OE2 1 Q8R3G1 UNP 247 E 
ATOM 1942 N N   . GLU A 1 248 ? -67.485 -6.314  43.127  1.0 42.35 ? 248 GLU A N   1 Q8R3G1 UNP 248 E 
ATOM 1943 C CA  . GLU A 1 248 ? -67.760 -5.838  41.767  1.0 42.35 ? 248 GLU A CA  1 Q8R3G1 UNP 248 E 
ATOM 1944 C C   . GLU A 1 248 ? -66.565 -6.182  40.822  1.0 42.35 ? 248 GLU A C   1 Q8R3G1 UNP 248 E 
ATOM 1945 C CB  . GLU A 1 248 ? -67.942 -4.299  41.851  1.0 42.35 ? 248 GLU A CB  1 Q8R3G1 UNP 248 E 
ATOM 1946 O O   . GLU A 1 248 ? -65.404 -6.066  41.206  1.0 42.35 ? 248 GLU A O   1 Q8R3G1 UNP 248 E 
ATOM 1947 C CG  . GLU A 1 248 ? -68.238 -3.639  40.507  1.0 42.35 ? 248 GLU A CG  1 Q8R3G1 UNP 248 E 
ATOM 1948 C CD  . GLU A 1 248 ? -68.671 -2.169  40.572  1.0 42.35 ? 248 GLU A CD  1 Q8R3G1 UNP 248 E 
ATOM 1949 O OE1 . GLU A 1 248 ? -68.347 -1.472  39.583  1.0 42.35 ? 248 GLU A OE1 1 Q8R3G1 UNP 248 E 
ATOM 1950 O OE2 . GLU A 1 248 ? -69.319 -1.766  41.562  1.0 42.35 ? 248 GLU A OE2 1 Q8R3G1 UNP 248 E 
ATOM 1951 N N   . SER A 1 249 ? -66.885 -6.542  39.568  1.0 47.91 ? 249 SER A N   1 Q8R3G1 UNP 249 S 
ATOM 1952 C CA  . SER A 1 249 ? -66.118 -6.370  38.310  1.0 47.91 ? 249 SER A CA  1 Q8R3G1 UNP 249 S 
ATOM 1953 C C   . SER A 1 249 ? -64.802 -7.117  38.005  1.0 47.91 ? 249 SER A C   1 Q8R3G1 UNP 249 S 
ATOM 1954 C CB  . SER A 1 249 ? -65.944 -4.878  38.015  1.0 47.91 ? 249 SER A CB  1 Q8R3G1 UNP 249 S 
ATOM 1955 O O   . SER A 1 249 ? -63.787 -6.977  38.675  1.0 47.91 ? 249 SER A O   1 Q8R3G1 UNP 249 S 
ATOM 1956 O OG  . SER A 1 249 ? -67.210 -4.356  37.654  1.0 47.91 ? 249 SER A OG  1 Q8R3G1 UNP 249 S 
ATOM 1957 N N   . GLY A 1 250 ? -64.781 -7.775  36.826  1.0 42.28 ? 250 GLY A N   1 Q8R3G1 UNP 250 G 
ATOM 1958 C CA  . GLY A 1 250 ? -63.547 -7.892  36.026  1.0 42.28 ? 250 GLY A CA  1 Q8R3G1 UNP 250 G 
ATOM 1959 C C   . GLY A 1 250 ? -63.236 -9.189  35.263  1.0 42.28 ? 250 GLY A C   1 Q8R3G1 UNP 250 G 
ATOM 1960 O O   . GLY A 1 250 ? -62.065 -9.513  35.102  1.0 42.28 ? 250 GLY A O   1 Q8R3G1 UNP 250 G 
ATOM 1961 N N   . SER A 1 251 ? -64.216 -9.957  34.770  1.0 44.36 ? 251 SER A N   1 Q8R3G1 UNP 251 S 
ATOM 1962 C CA  . SER A 1 251 ? -63.952 -11.075 33.838  1.0 44.36 ? 251 SER A CA  1 Q8R3G1 UNP 251 S 
ATOM 1963 C C   . SER A 1 251 ? -63.444 -10.605 32.464  1.0 44.36 ? 251 SER A C   1 Q8R3G1 UNP 251 S 
ATOM 1964 C CB  . SER A 1 251 ? -65.236 -11.879 33.587  1.0 44.36 ? 251 SER A CB  1 Q8R3G1 UNP 251 S 
ATOM 1965 O O   . SER A 1 251 ? -64.128 -9.808  31.820  1.0 44.36 ? 251 SER A O   1 Q8R3G1 UNP 251 S 
ATOM 1966 O OG  . SER A 1 251 ? -65.419 -12.876 34.565  1.0 44.36 ? 251 SER A OG  1 Q8R3G1 UNP 251 S 
ATOM 1967 N N   . ARG A 1 252 ? -62.336 -11.199 31.979  1.0 47.35 ? 252 ARG A N   1 Q8R3G1 UNP 252 R 
ATOM 1968 C CA  . ARG A 1 252 ? -62.084 -11.772 30.621  1.0 47.35 ? 252 ARG A CA  1 Q8R3G1 UNP 252 R 
ATOM 1969 C C   . ARG A 1 252 ? -60.571 -11.739 30.305  1.0 47.35 ? 252 ARG A C   1 Q8R3G1 UNP 252 R 
ATOM 1970 C CB  . ARG A 1 252 ? -62.893 -11.077 29.496  1.0 47.35 ? 252 ARG A CB  1 Q8R3G1 UNP 252 R 
ATOM 1971 O O   . ARG A 1 252 ? -59.993 -10.675 30.185  1.0 47.35 ? 252 ARG A O   1 Q8R3G1 UNP 252 R 
ATOM 1972 C CG  . ARG A 1 252 ? -64.317 -11.667 29.388  1.0 47.35 ? 252 ARG A CG  1 Q8R3G1 UNP 252 R 
ATOM 1973 C CD  . ARG A 1 252 ? -65.126 -11.155 28.190  1.0 47.35 ? 252 ARG A CD  1 Q8R3G1 UNP 252 R 
ATOM 1974 N NE  . ARG A 1 252 ? -65.844 -9.892  28.447  1.0 47.35 ? 252 ARG A NE  1 Q8R3G1 UNP 252 R 
ATOM 1975 N NH1 . ARG A 1 252 ? -67.279 -10.032 26.649  1.0 47.35 ? 252 ARG A NH1 1 Q8R3G1 UNP 252 R 
ATOM 1976 N NH2 . ARG A 1 252 ? -67.411 -8.282  28.015  1.0 47.35 ? 252 ARG A NH2 1 Q8R3G1 UNP 252 R 
ATOM 1977 C CZ  . ARG A 1 252 ? -66.836 -9.409  27.709  1.0 47.35 ? 252 ARG A CZ  1 Q8R3G1 UNP 252 R 
ATOM 1978 N N   . ARG A 1 253 ? -59.861 -12.876 30.310  1.0 42.07 ? 253 ARG A N   1 Q8R3G1 UNP 253 R 
ATOM 1979 C CA  . ARG A 1 253 ? -59.731 -13.910 29.248  1.0 42.07 ? 253 ARG A CA  1 Q8R3G1 UNP 253 R 
ATOM 1980 C C   . ARG A 1 253 ? -58.370 -13.775 28.537  1.0 42.07 ? 253 ARG A C   1 Q8R3G1 UNP 253 R 
ATOM 1981 C CB  . ARG A 1 253 ? -60.925 -13.918 28.256  1.0 42.07 ? 253 ARG A CB  1 Q8R3G1 UNP 253 R 
ATOM 1982 O O   . ARG A 1 253 ? -58.296 -13.173 27.475  1.0 42.07 ? 253 ARG A O   1 Q8R3G1 UNP 253 R 
ATOM 1983 C CG  . ARG A 1 253 ? -60.984 -15.162 27.347  1.0 42.07 ? 253 ARG A CG  1 Q8R3G1 UNP 253 R 
ATOM 1984 C CD  . ARG A 1 253 ? -62.165 -15.056 26.365  1.0 42.07 ? 253 ARG A CD  1 Q8R3G1 UNP 253 R 
ATOM 1985 N NE  . ARG A 1 253 ? -62.513 -16.356 25.750  1.0 42.07 ? 253 ARG A NE  1 Q8R3G1 UNP 253 R 
ATOM 1986 N NH1 . ARG A 1 253 ? -64.263 -15.630 24.445  1.0 42.07 ? 253 ARG A NH1 1 Q8R3G1 UNP 253 R 
ATOM 1987 N NH2 . ARG A 1 253 ? -63.778 -17.803 24.513  1.0 42.07 ? 253 ARG A NH2 1 Q8R3G1 UNP 253 R 
ATOM 1988 C CZ  . ARG A 1 253 ? -63.512 -16.590 24.911  1.0 42.07 ? 253 ARG A CZ  1 Q8R3G1 UNP 253 R 
ATOM 1989 N N   . MET A 1 254 ? -57.312 -14.367 29.099  1.0 47.52 ? 254 MET A N   1 Q8R3G1 UNP 254 M 
ATOM 1990 C CA  . MET A 1 254 ? -56.087 -14.646 28.334  1.0 47.52 ? 254 MET A CA  1 Q8R3G1 UNP 254 M 
ATOM 1991 C C   . MET A 1 254 ? -56.275 -15.938 27.534  1.0 47.52 ? 254 MET A C   1 Q8R3G1 UNP 254 M 
ATOM 1992 C CB  . MET A 1 254 ? -54.832 -14.700 29.218  1.0 47.52 ? 254 MET A CB  1 Q8R3G1 UNP 254 M 
ATOM 1993 O O   . MET A 1 254 ? -56.725 -16.955 28.062  1.0 47.52 ? 254 MET A O   1 Q8R3G1 UNP 254 M 
ATOM 1994 C CG  . MET A 1 254 ? -54.353 -13.292 29.594  1.0 47.52 ? 254 MET A CG  1 Q8R3G1 UNP 254 M 
ATOM 1995 S SD  . MET A 1 254 ? -52.674 -13.227 30.273  1.0 47.52 ? 254 MET A SD  1 Q8R3G1 UNP 254 M 
ATOM 1996 C CE  . MET A 1 254 ? -51.681 -13.469 28.772  1.0 47.52 ? 254 MET A CE  1 Q8R3G1 UNP 254 M 
ATOM 1997 N N   . GLN A 1 255 ? -56.007 -15.855 26.235  1.0 47.01 ? 255 GLN A N   1 Q8R3G1 UNP 255 Q 
ATOM 1998 C CA  . GLN A 1 255 ? -56.102 -16.954 25.285  1.0 47.01 ? 255 GLN A CA  1 Q8R3G1 UNP 255 Q 
ATOM 1999 C C   . GLN A 1 255 ? -54.834 -17.812 25.363  1.0 47.01 ? 255 GLN A C   1 Q8R3G1 UNP 255 Q 
ATOM 2000 C CB  . GLN A 1 255 ? -56.304 -16.375 23.872  1.0 47.01 ? 255 GLN A CB  1 Q8R3G1 UNP 255 Q 
ATOM 2001 O O   . GLN A 1 255 ? -53.726 -17.305 25.211  1.0 47.01 ? 255 GLN A O   1 Q8R3G1 UNP 255 Q 
ATOM 2002 C CG  . GLN A 1 255 ? -57.682 -15.710 23.688  1.0 47.01 ? 255 GLN A CG  1 Q8R3G1 UNP 255 Q 
ATOM 2003 C CD  . GLN A 1 255 ? -57.821 -14.974 22.355  1.0 47.01 ? 255 GLN A CD  1 Q8R3G1 UNP 255 Q 
ATOM 2004 N NE2 . GLN A 1 255 ? -59.021 -14.770 21.858  1.0 47.01 ? 255 GLN A NE2 1 Q8R3G1 UNP 255 Q 
ATOM 2005 O OE1 . GLN A 1 255 ? -56.870 -14.546 21.733  1.0 47.01 ? 255 GLN A OE1 1 Q8R3G1 UNP 255 Q 
ATOM 2006 N N   . ASN A 1 256 ? -55.017 -19.118 25.566  1.0 42.65 ? 256 ASN A N   1 Q8R3G1 UNP 256 N 
ATOM 2007 C CA  . ASN A 1 256 ? -54.006 -20.133 25.292  1.0 42.65 ? 256 ASN A CA  1 Q8R3G1 UNP 256 N 
ATOM 2008 C C   . ASN A 1 256 ? -53.681 -20.122 23.792  1.0 42.65 ? 256 ASN A C   1 Q8R3G1 UNP 256 N 
ATOM 2009 C CB  . ASN A 1 256 ? -54.552 -21.529 25.668  1.0 42.65 ? 256 ASN A CB  1 Q8R3G1 UNP 256 N 
ATOM 2010 O O   . ASN A 1 256 ? -54.558 -20.423 22.981  1.0 42.65 ? 256 ASN A O   1 Q8R3G1 UNP 256 N 
ATOM 2011 C CG  . ASN A 1 256 ? -54.453 -21.896 27.135  1.0 42.65 ? 256 ASN A CG  1 Q8R3G1 UNP 256 N 
ATOM 2012 N ND2 . ASN A 1 256 ? -54.604 -23.160 27.451  1.0 42.65 ? 256 ASN A ND2 1 Q8R3G1 UNP 256 N 
ATOM 2013 O OD1 . ASN A 1 256 ? -54.248 -21.078 28.010  1.0 42.65 ? 256 ASN A OD1 1 Q8R3G1 UNP 256 N 
ATOM 2014 N N   . PHE A 1 257 ? -52.428 -19.856 23.424  1.0 42.67 ? 257 PHE A N   1 Q8R3G1 UNP 257 F 
ATOM 2015 C CA  . PHE A 1 257 ? -51.914 -20.237 22.112  1.0 42.67 ? 257 PHE A CA  1 Q8R3G1 UNP 257 F 
ATOM 2016 C C   . PHE A 1 257 ? -51.357 -21.656 22.195  1.0 42.67 ? 257 PHE A C   1 Q8R3G1 UNP 257 F 
ATOM 2017 C CB  . PHE A 1 257 ? -50.903 -19.214 21.584  1.0 42.67 ? 257 PHE A CB  1 Q8R3G1 UNP 257 F 
ATOM 2018 O O   . PHE A 1 257 ? -50.408 -21.936 22.925  1.0 42.67 ? 257 PHE A O   1 Q8R3G1 UNP 257 F 
ATOM 2019 C CG  . PHE A 1 257 ? -51.587 -18.014 20.958  1.0 42.67 ? 257 PHE A CG  1 Q8R3G1 UNP 257 F 
ATOM 2020 C CD1 . PHE A 1 257 ? -52.046 -18.086 19.628  1.0 42.67 ? 257 PHE A CD1 1 Q8R3G1 UNP 257 F 
ATOM 2021 C CD2 . PHE A 1 257 ? -51.810 -16.846 21.710  1.0 42.67 ? 257 PHE A CD2 1 Q8R3G1 UNP 257 F 
ATOM 2022 C CE1 . PHE A 1 257 ? -52.718 -16.994 19.051  1.0 42.67 ? 257 PHE A CE1 1 Q8R3G1 UNP 257 F 
ATOM 2023 C CE2 . PHE A 1 257 ? -52.479 -15.752 21.131  1.0 42.67 ? 257 PHE A CE2 1 Q8R3G1 UNP 257 F 
ATOM 2024 C CZ  . PHE A 1 257 ? -52.932 -15.826 19.803  1.0 42.67 ? 257 PHE A CZ  1 Q8R3G1 UNP 257 F 
ATOM 2025 N N   . ALA A 1 258 ? -51.995 -22.562 21.458  1.0 45.09 ? 258 ALA A N   1 Q8R3G1 UNP 258 A 
ATOM 2026 C CA  . ALA A 1 258 ? -51.475 -23.891 21.206  1.0 45.09 ? 258 ALA A CA  1 Q8R3G1 UNP 258 A 
ATOM 2027 C C   . ALA A 1 258 ? -50.243 -23.786 20.297  1.0 45.09 ? 258 ALA A C   1 Q8R3G1 UNP 258 A 
ATOM 2028 C CB  . ALA A 1 258 ? -52.586 -24.744 20.579  1.0 45.09 ? 258 ALA A CB  1 Q8R3G1 UNP 258 A 
ATOM 2029 O O   . ALA A 1 258 ? -50.305 -23.196 19.218  1.0 45.09 ? 258 ALA A O   1 Q8R3G1 UNP 258 A 
ATOM 2030 N N   . PHE A 1 259 ? -49.139 -24.397 20.724  1.0 43.30 ? 259 PHE A N   1 Q8R3G1 UNP 259 F 
ATOM 2031 C CA  . PHE A 1 259 ? -48.026 -24.744 19.849  1.0 43.30 ? 259 PHE A CA  1 Q8R3G1 UNP 259 F 
ATOM 2032 C C   . PHE A 1 259 ? -48.550 -25.643 18.723  1.0 43.30 ? 259 PHE A C   1 Q8R3G1 UNP 259 F 
ATOM 2033 C CB  . PHE A 1 259 ? -46.949 -25.476 20.667  1.0 43.30 ? 259 PHE A CB  1 Q8R3G1 UNP 259 F 
ATOM 2034 O O   . PHE A 1 259 ? -48.943 -26.783 18.962  1.0 43.30 ? 259 PHE A O   1 Q8R3G1 UNP 259 F 
ATOM 2035 C CG  . PHE A 1 259 ? -45.896 -24.578 21.282  1.0 43.30 ? 259 PHE A CG  1 Q8R3G1 UNP 259 F 
ATOM 2036 C CD1 . PHE A 1 259 ? -44.677 -24.383 20.604  1.0 43.30 ? 259 PHE A CD1 1 Q8R3G1 UNP 259 F 
ATOM 2037 C CD2 . PHE A 1 259 ? -46.110 -23.955 22.527  1.0 43.30 ? 259 PHE A CD2 1 Q8R3G1 UNP 259 F 
ATOM 2038 C CE1 . PHE A 1 259 ? -43.673 -23.578 21.169  1.0 43.30 ? 259 PHE A CE1 1 Q8R3G1 UNP 259 F 
ATOM 2039 C CE2 . PHE A 1 259 ? -45.104 -23.149 23.091  1.0 43.30 ? 259 PHE A CE2 1 Q8R3G1 UNP 259 F 
ATOM 2040 C CZ  . PHE A 1 259 ? -43.886 -22.962 22.414  1.0 43.30 ? 259 PHE A CZ  1 Q8R3G1 UNP 259 F 
ATOM 2041 N N   . SER A 1 260 ? -48.570 -25.134 17.495  1.0 52.54 ? 260 SER A N   1 Q8R3G1 UNP 260 S 
ATOM 2042 C CA  . SER A 1 260 ? -48.893 -25.913 16.304  1.0 52.54 ? 260 SER A CA  1 Q8R3G1 UNP 260 S 
ATOM 2043 C C   . SER A 1 260 ? -48.042 -25.446 15.133  1.0 52.54 ? 260 SER A C   1 Q8R3G1 UNP 260 S 
ATOM 2044 C CB  . SER A 1 260 ? -50.383 -25.795 15.964  1.0 52.54 ? 260 SER A CB  1 Q8R3G1 UNP 260 S 
ATOM 2045 O O   . SER A 1 260 ? -48.121 -24.289 14.739  1.0 52.54 ? 260 SER A O   1 Q8R3G1 UNP 260 S 
ATOM 2046 O OG  . SER A 1 260 ? -50.645 -26.367 14.695  1.0 52.54 ? 260 SER A OG  1 Q8R3G1 UNP 260 S 
ATOM 2047 N N   . GLY A 1 261 ? -47.311 -26.400 14.553  1.0 50.30 ? 261 GLY A N   1 Q8R3G1 UNP 261 G 
ATOM 2048 C CA  . GLY A 1 261 ? -47.071 -26.488 13.112  1.0 50.30 ? 261 GLY A CA  1 Q8R3G1 UNP 261 G 
ATOM 2049 C C   . GLY A 1 261 ? -46.006 -25.567 12.525  1.0 50.30 ? 261 GLY A C   1 Q8R3G1 UNP 261 G 
ATOM 2050 O O   . GLY A 1 261 ? -46.159 -24.354 12.476  1.0 50.30 ? 261 GLY A O   1 Q8R3G1 UNP 261 G 
ATOM 2051 N N   . GLY A 1 262 ? -44.940 -26.175 12.004  1.0 49.40 ? 262 GLY A N   1 Q8R3G1 UNP 262 G 
ATOM 2052 C CA  . GLY A 1 262 ? -43.833 -25.488 11.347  1.0 49.40 ? 262 GLY A CA  1 Q8R3G1 UNP 262 G 
ATOM 2053 C C   . GLY A 1 262 ? -44.227 -24.639 10.132  1.0 49.40 ? 262 GLY A C   1 Q8R3G1 UNP 262 G 
ATOM 2054 O O   . GLY A 1 262 ? -45.093 -24.990 9.334   1.0 49.40 ? 262 GLY A O   1 Q8R3G1 UNP 262 G 
ATOM 2055 N N   . LEU A 1 263 ? -43.491 -23.541 9.969   1.0 58.73 ? 263 LEU A N   1 Q8R3G1 UNP 263 L 
ATOM 2056 C CA  . LEU A 1 263 ? -43.658 -22.483 8.965   1.0 58.73 ? 263 LEU A CA  1 Q8R3G1 UNP 263 L 
ATOM 2057 C C   . LEU A 1 263 ? -43.212 -22.863 7.530   1.0 58.73 ? 263 LEU A C   1 Q8R3G1 UNP 263 L 
ATOM 2058 C CB  . LEU A 1 263 ? -42.926 -21.226 9.495   1.0 58.73 ? 263 LEU A CB  1 Q8R3G1 UNP 263 L 
ATOM 2059 O O   . LEU A 1 263 ? -42.890 -21.985 6.741   1.0 58.73 ? 263 LEU A O   1 Q8R3G1 UNP 263 L 
ATOM 2060 C CG  . LEU A 1 263 ? -43.569 -20.587 10.743  1.0 58.73 ? 263 LEU A CG  1 Q8R3G1 UNP 263 L 
ATOM 2061 C CD1 . LEU A 1 263 ? -42.604 -19.592 11.387  1.0 58.73 ? 263 LEU A CD1 1 Q8R3G1 UNP 263 L 
ATOM 2062 C CD2 . LEU A 1 263 ? -44.857 -19.844 10.385  1.0 58.73 ? 263 LEU A CD2 1 Q8R3G1 UNP 263 L 
ATOM 2063 N N   . TYR A 1 264 ? -43.193 -24.152 7.168   1.0 61.06 ? 264 TYR A N   1 Q8R3G1 UNP 264 Y 
ATOM 2064 C CA  . TYR A 1 264 ? -42.771 -24.624 5.831   1.0 61.06 ? 264 TYR A CA  1 Q8R3G1 UNP 264 Y 
ATOM 2065 C C   . TYR A 1 264 ? -43.730 -25.641 5.180   1.0 61.06 ? 264 TYR A C   1 Q8R3G1 UNP 264 Y 
ATOM 2066 C CB  . TYR A 1 264 ? -41.310 -25.111 5.876   1.0 61.06 ? 264 TYR A CB  1 Q8R3G1 UNP 264 Y 
ATOM 2067 O O   . TYR A 1 264 ? -43.382 -26.285 4.195   1.0 61.06 ? 264 TYR A O   1 Q8R3G1 UNP 264 Y 
ATOM 2068 C CG  . TYR A 1 264 ? -40.305 -23.998 5.649   1.0 61.06 ? 264 TYR A CG  1 Q8R3G1 UNP 264 Y 
ATOM 2069 C CD1 . TYR A 1 264 ? -39.947 -23.641 4.333   1.0 61.06 ? 264 TYR A CD1 1 Q8R3G1 UNP 264 Y 
ATOM 2070 C CD2 . TYR A 1 264 ? -39.751 -23.303 6.741   1.0 61.06 ? 264 TYR A CD2 1 Q8R3G1 UNP 264 Y 
ATOM 2071 C CE1 . TYR A 1 264 ? -39.031 -22.596 4.109   1.0 61.06 ? 264 TYR A CE1 1 Q8R3G1 UNP 264 Y 
ATOM 2072 C CE2 . TYR A 1 264 ? -38.839 -22.252 6.521   1.0 61.06 ? 264 TYR A CE2 1 Q8R3G1 UNP 264 Y 
ATOM 2073 O OH  . TYR A 1 264 ? -37.598 -20.887 4.980   1.0 61.06 ? 264 TYR A OH  1 Q8R3G1 UNP 264 Y 
ATOM 2074 C CZ  . TYR A 1 264 ? -38.478 -21.898 5.202   1.0 61.06 ? 264 TYR A CZ  1 Q8R3G1 UNP 264 Y 
ATOM 2075 N N   . GLY A 1 265 ? -44.960 -25.781 5.682   1.0 59.50 ? 265 GLY A N   1 Q8R3G1 UNP 265 G 
ATOM 2076 C CA  . GLY A 1 265 ? -45.934 -26.758 5.170   1.0 59.50 ? 265 GLY A CA  1 Q8R3G1 UNP 265 G 
ATOM 2077 C C   . GLY A 1 265 ? -46.645 -26.404 3.853   1.0 59.50 ? 265 GLY A C   1 Q8R3G1 UNP 265 G 
ATOM 2078 O O   . GLY A 1 265 ? -47.591 -27.095 3.494   1.0 59.50 ? 265 GLY A O   1 Q8R3G1 UNP 265 G 
ATOM 2079 N N   . GLY A 1 266 ? -46.254 -25.332 3.154   1.0 63.73 ? 266 GLY A N   1 Q8R3G1 UNP 266 G 
ATOM 2080 C CA  . GLY A 1 266 ? -47.064 -24.719 2.088   1.0 63.73 ? 266 GLY A CA  1 Q8R3G1 UNP 266 G 
ATOM 2081 C C   . GLY A 1 266 ? -46.508 -24.752 0.660   1.0 63.73 ? 266 GLY A C   1 Q8R3G1 UNP 266 G 
ATOM 2082 O O   . GLY A 1 266 ? -47.062 -24.056 -0.186  1.0 63.73 ? 266 GLY A O   1 Q8R3G1 UNP 266 G 
ATOM 2083 N N   . LEU A 1 267 ? -45.432 -25.489 0.360   1.0 58.01 ? 267 LEU A N   1 Q8R3G1 UNP 267 L 
ATOM 2084 C CA  . LEU A 1 267 ? -44.884 -25.513 -1.005  1.0 58.01 ? 267 LEU A CA  1 Q8R3G1 UNP 267 L 
ATOM 2085 C C   . LEU A 1 267 ? -45.467 -26.671 -1.839  1.0 58.01 ? 267 LEU A C   1 Q8R3G1 UNP 267 L 
ATOM 2086 C CB  . LEU A 1 267 ? -43.348 -25.497 -0.992  1.0 58.01 ? 267 LEU A CB  1 Q8R3G1 UNP 267 L 
ATOM 2087 O O   . LEU A 1 267 ? -45.474 -27.812 -1.371  1.0 58.01 ? 267 LEU A O   1 Q8R3G1 UNP 267 L 
ATOM 2088 C CG  . LEU A 1 267 ? -42.746 -24.186 -0.447  1.0 58.01 ? 267 LEU A CG  1 Q8R3G1 UNP 267 L 
ATOM 2089 C CD1 . LEU A 1 267 ? -41.221 -24.298 -0.433  1.0 58.01 ? 267 LEU A CD1 1 Q8R3G1 UNP 267 L 
ATOM 2090 C CD2 . LEU A 1 267 ? -43.113 -22.953 -1.282  1.0 58.01 ? 267 LEU A CD2 1 Q8R3G1 UNP 267 L 
ATOM 2091 N N   . PRO A 1 268 ? -45.956 -26.398 -3.066  1.0 61.28 ? 268 PRO A N   1 Q8R3G1 UNP 268 P 
ATOM 2092 C CA  . PRO A 1 268 ? -46.533 -27.412 -3.944  1.0 61.28 ? 268 PRO A CA  1 Q8R3G1 UNP 268 P 
ATOM 2093 C C   . PRO A 1 268 ? -45.464 -28.417 -4.431  1.0 61.28 ? 268 PRO A C   1 Q8R3G1 UNP 268 P 
ATOM 2094 C CB  . PRO A 1 268 ? -47.157 -26.633 -5.106  1.0 61.28 ? 268 PRO A CB  1 Q8R3G1 UNP 268 P 
ATOM 2095 O O   . PRO A 1 268 ? -44.335 -28.015 -4.722  1.0 61.28 ? 268 PRO A O   1 Q8R3G1 UNP 268 P 
ATOM 2096 C CG  . PRO A 1 268 ? -46.313 -25.366 -5.181  1.0 61.28 ? 268 PRO A CG  1 Q8R3G1 UNP 268 P 
ATOM 2097 C CD  . PRO A 1 268 ? -45.978 -25.096 -3.720  1.0 61.28 ? 268 PRO A CD  1 Q8R3G1 UNP 268 P 
ATOM 2098 N N   . PRO A 1 269 ? -45.799 -29.714 -4.563  1.0 62.43 ? 269 PRO A N   1 Q8R3G1 UNP 269 P 
ATOM 2099 C CA  . PRO A 1 269 ? -44.882 -30.734 -5.059  1.0 62.43 ? 269 PRO A CA  1 Q8R3G1 UNP 269 P 
ATOM 2100 C C   . PRO A 1 269 ? -44.731 -30.636 -6.584  1.0 62.43 ? 269 PRO A C   1 Q8R3G1 UNP 269 P 
ATOM 2101 C CB  . PRO A 1 269 ? -45.480 -32.069 -4.597  1.0 62.43 ? 269 PRO A CB  1 Q8R3G1 UNP 269 P 
ATOM 2102 O O   . PRO A 1 269 ? -45.713 -30.582 -7.324  1.0 62.43 ? 269 PRO A O   1 Q8R3G1 UNP 269 P 
ATOM 2103 C CG  . PRO A 1 269 ? -46.983 -31.795 -4.548  1.0 62.43 ? 269 PRO A CG  1 Q8R3G1 UNP 269 P 
ATOM 2104 C CD  . PRO A 1 269 ? -47.070 -30.311 -4.187  1.0 62.43 ? 269 PRO A CD  1 Q8R3G1 UNP 269 P 
ATOM 2105 N N   . THR A 1 270 ? -43.494 -30.651 -7.077  1.0 54.75 ? 270 THR A N   1 Q8R3G1 UNP 270 T 
ATOM 2106 C CA  . THR A 1 270 ? -43.208 -30.793 -8.510  1.0 54.75 ? 270 THR A CA  1 Q8R3G1 UNP 270 T 
ATOM 2107 C C   . THR A 1 270 ? -43.342 -32.264 -8.907  1.0 54.75 ? 270 THR A C   1 Q8R3G1 UNP 270 T 
ATOM 2108 C CB  . THR A 1 270 ? -41.814 -30.250 -8.863  1.0 54.75 ? 270 THR A CB  1 Q8R3G1 UNP 270 T 
ATOM 2109 O O   . THR A 1 270 ? -42.496 -33.086 -8.556  1.0 54.75 ? 270 THR A O   1 Q8R3G1 UNP 270 T 
ATOM 2110 C CG2 . THR A 1 270 ? -41.719 -28.740 -8.644  1.0 54.75 ? 270 THR A CG2 1 Q8R3G1 UNP 270 T 
ATOM 2111 O OG1 . THR A 1 270 ? -40.832 -30.858 -8.057  1.0 54.75 ? 270 THR A OG1 1 Q8R3G1 UNP 270 T 
ATOM 2112 N N   . HIS A 1 271 ? -44.415 -32.603 -9.622  1.0 48.67 ? 271 HIS A N   1 Q8R3G1 UNP 271 H 
ATOM 2113 C CA  . HIS A 1 271 ? -44.629 -33.916 -10.229 1.0 48.67 ? 271 HIS A CA  1 Q8R3G1 UNP 271 H 
ATOM 2114 C C   . HIS A 1 271 ? -43.783 -34.077 -11.503 1.0 48.67 ? 271 HIS A C   1 Q8R3G1 UNP 271 H 
ATOM 2115 C CB  . HIS A 1 271 ? -46.120 -34.090 -10.572 1.0 48.67 ? 271 HIS A CB  1 Q8R3G1 UNP 271 H 
ATOM 2116 O O   . HIS A 1 271 ? -43.829 -33.237 -12.397 1.0 48.67 ? 271 HIS A O   1 Q8R3G1 UNP 271 H 
ATOM 2117 C CG  . HIS A 1 271 ? -47.008 -34.434 -9.402  1.0 48.67 ? 271 HIS A CG  1 Q8R3G1 UNP 271 H 
ATOM 2118 C CD2 . HIS A 1 271 ? -47.464 -33.593 -8.420  1.0 48.67 ? 271 HIS A CD2 1 Q8R3G1 UNP 271 H 
ATOM 2119 N ND1 . HIS A 1 271 ? -47.557 -35.673 -9.162  1.0 48.67 ? 271 HIS A ND1 1 Q8R3G1 UNP 271 H 
ATOM 2120 C CE1 . HIS A 1 271 ? -48.316 -35.585 -8.058  1.0 48.67 ? 271 HIS A CE1 1 Q8R3G1 UNP 271 H 
ATOM 2121 N NE2 . HIS A 1 271 ? -48.286 -34.338 -7.565  1.0 48.67 ? 271 HIS A NE2 1 Q8R3G1 UNP 271 H 
ATOM 2122 N N   . SER A 1 272 ? -43.064 -35.190 -11.619 1.0 43.79 ? 272 SER A N   1 Q8R3G1 UNP 272 S 
ATOM 2123 C CA  . SER A 1 272 ? -42.952 -35.945 -12.875 1.0 43.79 ? 272 SER A CA  1 Q8R3G1 UNP 272 S 
ATOM 2124 C C   . SER A 1 272 ? -42.658 -37.412 -12.544 1.0 43.79 ? 272 SER A C   1 Q8R3G1 UNP 272 S 
ATOM 2125 C CB  . SER A 1 272 ? -41.971 -35.357 -13.904 1.0 43.79 ? 272 SER A CB  1 Q8R3G1 UNP 272 S 
ATOM 2126 O O   . SER A 1 272 ? -41.571 -37.794 -12.121 1.0 43.79 ? 272 SER A O   1 Q8R3G1 UNP 272 S 
ATOM 2127 O OG  . SER A 1 272 ? -40.881 -34.689 -13.309 1.0 43.79 ? 272 SER A OG  1 Q8R3G1 UNP 272 S 
ATOM 2128 N N   . GLU A 1 273 ? -43.728 -38.198 -12.666 1.0 42.86 ? 273 GLU A N   1 Q8R3G1 UNP 273 E 
ATOM 2129 C CA  . GLU A 1 273 ? -43.791 -39.651 -12.852 1.0 42.86 ? 273 GLU A CA  1 Q8R3G1 UNP 273 E 
ATOM 2130 C C   . GLU A 1 273 ? -42.939 -40.065 -14.080 1.0 42.86 ? 273 GLU A C   1 Q8R3G1 UNP 273 E 
ATOM 2131 C CB  . GLU A 1 273 ? -45.287 -39.935 -13.080 1.0 42.86 ? 273 GLU A CB  1 Q8R3G1 UNP 273 E 
ATOM 2132 O O   . GLU A 1 273 ? -42.615 -39.217 -14.902 1.0 42.86 ? 273 GLU A O   1 Q8R3G1 UNP 273 E 
ATOM 2133 C CG  . GLU A 1 273 ? -46.171 -39.714 -11.845 1.0 42.86 ? 273 GLU A CG  1 Q8R3G1 UNP 273 E 
ATOM 2134 C CD  . GLU A 1 273 ? -47.646 -39.928 -12.204 1.0 42.86 ? 273 GLU A CD  1 Q8R3G1 UNP 273 E 
ATOM 2135 O OE1 . GLU A 1 273 ? -48.129 -41.064 -12.003 1.0 42.86 ? 273 GLU A OE1 1 Q8R3G1 UNP 273 E 
ATOM 2136 O OE2 . GLU A 1 273 ? -48.256 -38.948 -12.683 1.0 42.86 ? 273 GLU A OE2 1 Q8R3G1 UNP 273 E 
ATOM 2137 N N   . THR A 1 274 ? -42.520 -41.302 -14.356 1.0 41.53 ? 274 THR A N   1 Q8R3G1 UNP 274 T 
ATOM 2138 C CA  . THR A 1 274 ? -43.034 -42.654 -14.082 1.0 41.53 ? 274 THR A CA  1 Q8R3G1 UNP 274 T 
ATOM 2139 C C   . THR A 1 274 ? -41.954 -43.644 -14.570 1.0 41.53 ? 274 THR A C   1 Q8R3G1 UNP 274 T 
ATOM 2140 C CB  . THR A 1 274 ? -44.286 -42.967 -14.955 1.0 41.53 ? 274 THR A CB  1 Q8R3G1 UNP 274 T 
ATOM 2141 O O   . THR A 1 274 ? -41.185 -43.308 -15.468 1.0 41.53 ? 274 THR A O   1 Q8R3G1 UNP 274 T 
ATOM 2142 C CG2 . THR A 1 274 ? -45.459 -43.540 -14.156 1.0 41.53 ? 274 THR A CG2 1 Q8R3G1 UNP 274 T 
ATOM 2143 O OG1 . THR A 1 274 ? -44.756 -41.875 -15.712 1.0 41.53 ? 274 THR A OG1 1 Q8R3G1 UNP 274 T 
ATOM 2144 N N   . GLY A 1 275 ? -41.949 -44.894 -14.088 1.0 39.48 ? 275 GLY A N   1 Q8R3G1 UNP 275 G 
ATOM 2145 C CA  . GLY A 1 275 ? -41.417 -46.018 -14.884 1.0 39.48 ? 275 GLY A CA  1 Q8R3G1 UNP 275 G 
ATOM 2146 C C   . GLY A 1 275 ? -40.376 -46.919 -14.216 1.0 39.48 ? 275 GLY A C   1 Q8R3G1 UNP 275 G 
ATOM 2147 O O   . GLY A 1 275 ? -39.176 -46.717 -14.327 1.0 39.48 ? 275 GLY A O   1 Q8R3G1 UNP 275 G 
ATOM 2148 N N   . SER A 1 276 ? -40.883 -47.962 -13.571 1.0 41.79 ? 276 SER A N   1 Q8R3G1 UNP 276 S 
ATOM 2149 C CA  . SER A 1 276 ? -40.238 -49.144 -12.983 1.0 41.79 ? 276 SER A CA  1 Q8R3G1 UNP 276 S 
ATOM 2150 C C   . SER A 1 276 ? -39.264 -49.940 -13.875 1.0 41.79 ? 276 SER A C   1 Q8R3G1 UNP 276 S 
ATOM 2151 C CB  . SER A 1 276 ? -41.408 -50.099 -12.700 1.0 41.79 ? 276 SER A CB  1 Q8R3G1 UNP 276 S 
ATOM 2152 O O   . SER A 1 276 ? -39.600 -50.214 -15.024 1.0 41.79 ? 276 SER A O   1 Q8R3G1 UNP 276 S 
ATOM 2153 O OG  . SER A 1 276 ? -42.194 -50.242 -13.879 1.0 41.79 ? 276 SER A OG  1 Q8R3G1 UNP 276 S 
ATOM 2154 N N   . GLN A 1 277 ? -38.174 -50.466 -13.290 1.0 42.39 ? 277 GLN A N   1 Q8R3G1 UNP 277 Q 
ATOM 2155 C CA  . GLN A 1 277 ? -37.851 -51.908 -13.083 1.0 42.39 ? 277 GLN A CA  1 Q8R3G1 UNP 277 Q 
ATOM 2156 C C   . GLN A 1 277 ? -36.332 -52.094 -12.786 1.0 42.39 ? 277 GLN A C   1 Q8R3G1 UNP 277 Q 
ATOM 2157 C CB  . GLN A 1 277 ? -38.241 -52.821 -14.267 1.0 42.39 ? 277 GLN A CB  1 Q8R3G1 UNP 277 Q 
ATOM 2158 O O   . GLN A 1 277 ? -35.523 -51.391 -13.391 1.0 42.39 ? 277 GLN A O   1 Q8R3G1 UNP 277 Q 
ATOM 2159 C CG  . GLN A 1 277 ? -39.718 -53.282 -14.265 1.0 42.39 ? 277 GLN A CG  1 Q8R3G1 UNP 277 Q 
ATOM 2160 C CD  . GLN A 1 277 ? -40.088 -54.274 -13.163 1.0 42.39 ? 277 GLN A CD  1 Q8R3G1 UNP 277 Q 
ATOM 2161 N NE2 . GLN A 1 277 ? -41.356 -54.419 -12.846 1.0 42.39 ? 277 GLN A NE2 1 Q8R3G1 UNP 277 Q 
ATOM 2162 O OE1 . GLN A 1 277 ? -39.263 -54.931 -12.557 1.0 42.39 ? 277 GLN A OE1 1 Q8R3G1 UNP 277 Q 
ATOM 2163 N N   . PRO A 1 278 ? -35.902 -53.001 -11.875 1.0 41.07 ? 278 PRO A N   1 Q8R3G1 UNP 278 P 
ATOM 2164 C CA  . PRO A 1 278 ? -34.509 -53.099 -11.418 1.0 41.07 ? 278 PRO A CA  1 Q8R3G1 UNP 278 P 
ATOM 2165 C C   . PRO A 1 278 ? -33.765 -54.336 -11.960 1.0 41.07 ? 278 PRO A C   1 Q8R3G1 UNP 278 P 
ATOM 2166 C CB  . PRO A 1 278 ? -34.654 -53.191 -9.896  1.0 41.07 ? 278 PRO A CB  1 Q8R3G1 UNP 278 P 
ATOM 2167 O O   . PRO A 1 278 ? -34.328 -55.420 -11.969 1.0 41.07 ? 278 PRO A O   1 Q8R3G1 UNP 278 P 
ATOM 2168 C CG  . PRO A 1 278 ? -35.914 -54.046 -9.711  1.0 41.07 ? 278 PRO A CG  1 Q8R3G1 UNP 278 P 
ATOM 2169 C CD  . PRO A 1 278 ? -36.729 -53.821 -10.989 1.0 41.07 ? 278 PRO A CD  1 Q8R3G1 UNP 278 P 
ATOM 2170 N N   . HIS A 1 279 ? -32.470 -54.216 -12.288 1.0 40.42 ? 279 HIS A N   1 Q8R3G1 UNP 279 H 
ATOM 2171 C CA  . HIS A 1 279 ? -31.496 -55.322 -12.214 1.0 40.42 ? 279 HIS A CA  1 Q8R3G1 UNP 279 H 
ATOM 2172 C C   . HIS A 1 279 ? -30.039 -54.812 -12.223 1.0 40.42 ? 279 HIS A C   1 Q8R3G1 UNP 279 H 
ATOM 2173 C CB  . HIS A 1 279 ? -31.701 -56.372 -13.333 1.0 40.42 ? 279 HIS A CB  1 Q8R3G1 UNP 279 H 
ATOM 2174 O O   . HIS A 1 279 ? -29.594 -54.167 -13.160 1.0 40.42 ? 279 HIS A O   1 Q8R3G1 UNP 279 H 
ATOM 2175 C CG  . HIS A 1 279 ? -32.570 -57.546 -12.925 1.0 40.42 ? 279 HIS A CG  1 Q8R3G1 UNP 279 H 
ATOM 2176 C CD2 . HIS A 1 279 ? -33.776 -57.905 -13.470 1.0 40.42 ? 279 HIS A CD2 1 Q8R3G1 UNP 279 H 
ATOM 2177 N ND1 . HIS A 1 279 ? -32.316 -58.438 -11.904 1.0 40.42 ? 279 HIS A ND1 1 Q8R3G1 UNP 279 H 
ATOM 2178 C CE1 . HIS A 1 279 ? -33.347 -59.298 -11.832 1.0 40.42 ? 279 HIS A CE1 1 Q8R3G1 UNP 279 H 
ATOM 2179 N NE2 . HIS A 1 279 ? -34.255 -59.022 -12.775 1.0 40.42 ? 279 HIS A NE2 1 Q8R3G1 UNP 279 H 
ATOM 2180 N N   . GLY A 1 280 ? -29.312 -55.136 -11.149 1.0 38.89 ? 280 GLY A N   1 Q8R3G1 UNP 280 G 
ATOM 2181 C CA  . GLY A 1 280 ? -28.010 -55.812 -11.174 1.0 38.89 ? 280 GLY A CA  1 Q8R3G1 UNP 280 G 
ATOM 2182 C C   . GLY A 1 280 ? -26.774 -55.223 -11.885 1.0 38.89 ? 280 GLY A C   1 Q8R3G1 UNP 280 G 
ATOM 2183 O O   . GLY A 1 280 ? -26.603 -55.408 -13.076 1.0 38.89 ? 280 GLY A O   1 Q8R3G1 UNP 280 G 
ATOM 2184 N N   . ILE A 1 281 ? -25.828 -54.778 -11.042 1.0 43.42 ? 281 ILE A N   1 Q8R3G1 UNP 281 I 
ATOM 2185 C CA  . ILE A 1 281 ? -24.371 -55.069 -11.022 1.0 43.42 ? 281 ILE A CA  1 Q8R3G1 UNP 281 I 
ATOM 2186 C C   . ILE A 1 281 ? -23.448 -54.585 -12.178 1.0 43.42 ? 281 ILE A C   1 Q8R3G1 UNP 281 I 
ATOM 2187 C CB  . ILE A 1 281 ? -24.073 -56.556 -10.638 1.0 43.42 ? 281 ILE A CB  1 Q8R3G1 UNP 281 I 
ATOM 2188 O O   . ILE A 1 281 ? -23.669 -54.849 -13.349 1.0 43.42 ? 281 ILE A O   1 Q8R3G1 UNP 281 I 
ATOM 2189 C CG1 . ILE A 1 281 ? -25.200 -57.305 -9.885  1.0 43.42 ? 281 ILE A CG1 1 Q8R3G1 UNP 281 I 
ATOM 2190 C CG2 . ILE A 1 281 ? -22.811 -56.612 -9.755  1.0 43.42 ? 281 ILE A CG2 1 Q8R3G1 UNP 281 I 
ATOM 2191 C CD1 . ILE A 1 281 ? -24.887 -58.739 -9.440  1.0 43.42 ? 281 ILE A CD1 1 Q8R3G1 UNP 281 I 
ATOM 2192 N N   . HIS A 1 282 ? -22.296 -54.037 -11.748 1.0 38.73 ? 282 HIS A N   1 Q8R3G1 UNP 282 H 
ATOM 2193 C CA  . HIS A 1 282 ? -21.000 -53.848 -12.437 1.0 38.73 ? 282 HIS A CA  1 Q8R3G1 UNP 282 H 
ATOM 2194 C C   . HIS A 1 282 ? -20.735 -52.514 -13.170 1.0 38.73 ? 282 HIS A C   1 Q8R3G1 UNP 282 H 
ATOM 2195 C CB  . HIS A 1 282 ? -20.576 -55.074 -13.269 1.0 38.73 ? 282 HIS A CB  1 Q8R3G1 UNP 282 H 
ATOM 2196 O O   . HIS A 1 282 ? -21.067 -52.331 -14.328 1.0 38.73 ? 282 HIS A O   1 Q8R3G1 UNP 282 H 
ATOM 2197 C CG  . HIS A 1 282 ? -20.447 -56.347 -12.472 1.0 38.73 ? 282 HIS A CG  1 Q8R3G1 UNP 282 H 
ATOM 2198 C CD2 . HIS A 1 282 ? -21.357 -57.365 -12.415 1.0 38.73 ? 282 HIS A CD2 1 Q8R3G1 UNP 282 H 
ATOM 2199 N ND1 . HIS A 1 282 ? -19.369 -56.729 -11.705 1.0 38.73 ? 282 HIS A ND1 1 Q8R3G1 UNP 282 H 
ATOM 2200 C CE1 . HIS A 1 282 ? -19.642 -57.930 -11.167 1.0 38.73 ? 282 HIS A CE1 1 Q8R3G1 UNP 282 H 
ATOM 2201 N NE2 . HIS A 1 282 ? -20.851 -58.351 -11.558 1.0 38.73 ? 282 HIS A NE2 1 Q8R3G1 UNP 282 H 
ATOM 2202 N N   . GLY A 1 283 ? -20.013 -51.622 -12.478 1.0 36.94 ? 283 GLY A N   1 Q8R3G1 UNP 283 G 
ATOM 2203 C CA  . GLY A 1 283 ? -18.605 -51.305 -12.770 1.0 36.94 ? 283 GLY A CA  1 Q8R3G1 UNP 283 G 
ATOM 2204 C C   . GLY A 1 283 ? -18.213 -50.576 -14.068 1.0 36.94 ? 283 GLY A C   1 Q8R3G1 UNP 283 G 
ATOM 2205 O O   . GLY A 1 283 ? -18.460 -51.043 -15.168 1.0 36.94 ? 283 GLY A O   1 Q8R3G1 UNP 283 G 
ATOM 2206 N N   . THR A 1 284 ? -17.358 -49.566 -13.864 1.0 39.64 ? 284 THR A N   1 Q8R3G1 UNP 284 T 
ATOM 2207 C CA  . THR A 1 284 ? -16.390 -48.922 -14.782 1.0 39.64 ? 284 THR A CA  1 Q8R3G1 UNP 284 T 
ATOM 2208 C C   . THR A 1 284 ? -16.819 -47.641 -15.508 1.0 39.64 ? 284 THR A C   1 Q8R3G1 UNP 284 T 
ATOM 2209 C CB  . THR A 1 284 ? -15.575 -49.879 -15.671 1.0 39.64 ? 284 THR A CB  1 Q8R3G1 UNP 284 T 
ATOM 2210 O O   . THR A 1 284 ? -17.910 -47.499 -16.042 1.0 39.64 ? 284 THR A O   1 Q8R3G1 UNP 284 T 
ATOM 2211 C CG2 . THR A 1 284 ? -14.868 -50.963 -14.854 1.0 39.64 ? 284 THR A CG2 1 Q8R3G1 UNP 284 T 
ATOM 2212 O OG1 . THR A 1 284 ? -16.348 -50.505 -16.655 1.0 39.64 ? 284 THR A OG1 1 Q8R3G1 UNP 284 T 
ATOM 2213 N N   . ALA A 1 285 ? -15.909 -46.668 -15.424 1.0 40.48 ? 285 ALA A N   1 Q8R3G1 UNP 285 A 
ATOM 2214 C CA  . ALA A 1 285 ? -16.005 -45.284 -15.861 1.0 40.48 ? 285 ALA A CA  1 Q8R3G1 UNP 285 A 
ATOM 2215 C C   . ALA A 1 285 ? -15.564 -45.120 -17.316 1.0 40.48 ? 285 ALA A C   1 Q8R3G1 UNP 285 A 
ATOM 2216 C CB  . ALA A 1 285 ? -15.026 -44.508 -14.965 1.0 40.48 ? 285 ALA A CB  1 Q8R3G1 UNP 285 A 
ATOM 2217 O O   . ALA A 1 285 ? -14.599 -45.778 -17.672 1.0 40.48 ? 285 ALA A O   1 Q8R3G1 UNP 285 A 
ATOM 2218 N N   . LEU A 1 286 ? -16.148 -44.174 -18.068 1.0 49.74 ? 286 LEU A N   1 Q8R3G1 UNP 286 L 
ATOM 2219 C CA  . LEU A 1 286 ? -15.488 -43.385 -19.123 1.0 49.74 ? 286 LEU A CA  1 Q8R3G1 UNP 286 L 
ATOM 2220 C C   . LEU A 1 286 ? -16.330 -42.129 -19.472 1.0 49.74 ? 286 LEU A C   1 Q8R3G1 UNP 286 L 
ATOM 2221 C CB  . LEU A 1 286 ? -15.233 -44.201 -20.420 1.0 49.74 ? 286 LEU A CB  1 Q8R3G1 UNP 286 L 
ATOM 2222 O O   . LEU A 1 286 ? -17.505 -42.231 -19.793 1.0 49.74 ? 286 LEU A O   1 Q8R3G1 UNP 286 L 
ATOM 2223 C CG  . LEU A 1 286 ? -14.063 -45.215 -20.459 1.0 49.74 ? 286 LEU A CG  1 Q8R3G1 UNP 286 L 
ATOM 2224 C CD1 . LEU A 1 286 ? -13.824 -45.687 -21.888 1.0 49.74 ? 286 LEU A CD1 1 Q8R3G1 UNP 286 L 
ATOM 2225 C CD2 . LEU A 1 286 ? -12.734 -44.652 -19.932 1.0 49.74 ? 286 LEU A CD2 1 Q8R3G1 UNP 286 L 
ATOM 2226 N N   . ILE A 1 287 ? -15.682 -40.961 -19.389 1.0 47.60 ? 287 ILE A N   1 Q8R3G1 UNP 287 I 
ATOM 2227 C CA  . ILE A 1 287 ? -15.567 -39.919 -20.435 1.0 47.60 ? 287 ILE A CA  1 Q8R3G1 UNP 287 I 
ATOM 2228 C C   . ILE A 1 287 ? -16.852 -39.356 -21.094 1.0 47.60 ? 287 ILE A C   1 Q8R3G1 UNP 287 I 
ATOM 2229 C CB  . ILE A 1 287 ? -14.528 -40.404 -21.487 1.0 47.60 ? 287 ILE A CB  1 Q8R3G1 UNP 287 I 
ATOM 2230 O O   . ILE A 1 287 ? -17.464 -39.992 -21.938 1.0 47.60 ? 287 ILE A O   1 Q8R3G1 UNP 287 I 
ATOM 2231 C CG1 . ILE A 1 287 ? -13.153 -40.647 -20.805 1.0 47.60 ? 287 ILE A CG1 1 Q8R3G1 UNP 287 I 
ATOM 2232 C CG2 . ILE A 1 287 ? -14.363 -39.428 -22.668 1.0 47.60 ? 287 ILE A CG2 1 Q8R3G1 UNP 287 I 
ATOM 2233 C CD1 . ILE A 1 287 ? -12.090 -41.283 -21.708 1.0 47.60 ? 287 ILE A CD1 1 Q8R3G1 UNP 287 I 
ATOM 2234 N N   . GLY A 1 288 ? -17.077 -38.052 -20.863 1.0 40.79 ? 288 GLY A N   1 Q8R3G1 UNP 288 G 
ATOM 2235 C CA  . GLY A 1 288 ? -17.090 -37.043 -21.936 1.0 40.79 ? 288 GLY A CA  1 Q8R3G1 UNP 288 G 
ATOM 2236 C C   . GLY A 1 288 ? -18.417 -36.666 -22.612 1.0 40.79 ? 288 GLY A C   1 Q8R3G1 UNP 288 G 
ATOM 2237 O O   . GLY A 1 288 ? -18.980 -37.438 -23.371 1.0 40.79 ? 288 GLY A O   1 Q8R3G1 UNP 288 G 
ATOM 2238 N N   . GLY A 1 289 ? -18.773 -35.381 -22.481 1.0 43.45 ? 289 GLY A N   1 Q8R3G1 UNP 289 G 
ATOM 2239 C CA  . GLY A 1 289 ? -19.486 -34.619 -23.513 1.0 43.45 ? 289 GLY A CA  1 Q8R3G1 UNP 289 G 
ATOM 2240 C C   . GLY A 1 289 ? -20.993 -34.457 -23.320 1.0 43.45 ? 289 GLY A C   1 Q8R3G1 UNP 289 G 
ATOM 2241 O O   . GLY A 1 289 ? -21.743 -35.409 -23.470 1.0 43.45 ? 289 GLY A O   1 Q8R3G1 UNP 289 G 
ATOM 2242 N N   . LEU A 1 290 ? -21.432 -33.223 -23.049 1.0 47.89 ? 290 LEU A N   1 Q8R3G1 UNP 290 L 
ATOM 2243 C CA  . LEU A 1 290 ? -22.349 -32.425 -23.887 1.0 47.89 ? 290 LEU A CA  1 Q8R3G1 UNP 290 L 
ATOM 2244 C C   . LEU A 1 290 ? -22.789 -31.160 -23.108 1.0 47.89 ? 290 LEU A C   1 Q8R3G1 UNP 290 L 
ATOM 2245 C CB  . LEU A 1 290 ? -23.586 -33.215 -24.370 1.0 47.89 ? 290 LEU A CB  1 Q8R3G1 UNP 290 L 
ATOM 2246 O O   . LEU A 1 290 ? -23.084 -31.256 -21.916 1.0 47.89 ? 290 LEU A O   1 Q8R3G1 UNP 290 L 
ATOM 2247 C CG  . LEU A 1 290 ? -23.354 -34.030 -25.666 1.0 47.89 ? 290 LEU A CG  1 Q8R3G1 UNP 290 L 
ATOM 2248 C CD1 . LEU A 1 290 ? -24.519 -34.992 -25.886 1.0 47.89 ? 290 LEU A CD1 1 Q8R3G1 UNP 290 L 
ATOM 2249 C CD2 . LEU A 1 290 ? -23.218 -33.140 -26.904 1.0 47.89 ? 290 LEU A CD2 1 Q8R3G1 UNP 290 L 
ATOM 2250 N N   . PRO A 1 291 ? -22.805 -29.967 -23.735 1.0 53.74 ? 291 PRO A N   1 Q8R3G1 UNP 291 P 
ATOM 2251 C CA  . PRO A 1 291 ? -23.179 -28.719 -23.077 1.0 53.74 ? 291 PRO A CA  1 Q8R3G1 UNP 291 P 
ATOM 2252 C C   . PRO A 1 291 ? -24.701 -28.502 -23.114 1.0 53.74 ? 291 PRO A C   1 Q8R3G1 UNP 291 P 
ATOM 2253 C CB  . PRO A 1 291 ? -22.415 -27.636 -23.842 1.0 53.74 ? 291 PRO A CB  1 Q8R3G1 UNP 291 P 
ATOM 2254 O O   . PRO A 1 291 ? -25.342 -28.685 -24.147 1.0 53.74 ? 291 PRO A O   1 Q8R3G1 UNP 291 P 
ATOM 2255 C CG  . PRO A 1 291 ? -22.393 -28.174 -25.274 1.0 53.74 ? 291 PRO A CG  1 Q8R3G1 UNP 291 P 
ATOM 2256 C CD  . PRO A 1 291 ? -22.391 -29.696 -25.106 1.0 53.74 ? 291 PRO A CD  1 Q8R3G1 UNP 291 P 
ATOM 2257 N N   . MET A 1 292 ? -25.269 -28.070 -21.987 1.0 65.48 ? 292 MET A N   1 Q8R3G1 UNP 292 M 
ATOM 2258 C CA  . MET A 1 292 ? -26.662 -27.622 -21.881 1.0 65.48 ? 292 MET A CA  1 Q8R3G1 UNP 292 M 
ATOM 2259 C C   . MET A 1 292 ? -26.806 -26.188 -22.425 1.0 65.48 ? 292 MET A C   1 Q8R3G1 UNP 292 M 
ATOM 2260 C CB  . MET A 1 292 ? -27.111 -27.669 -20.411 1.0 65.48 ? 292 MET A CB  1 Q8R3G1 UNP 292 M 
ATOM 2261 O O   . MET A 1 292 ? -26.016 -25.324 -22.033 1.0 65.48 ? 292 MET A O   1 Q8R3G1 UNP 292 M 
ATOM 2262 C CG  . MET A 1 292 ? -27.346 -29.101 -19.916 1.0 65.48 ? 292 MET A CG  1 Q8R3G1 UNP 292 M 
ATOM 2263 S SD  . MET A 1 292 ? -28.851 -29.886 -20.556 1.0 65.48 ? 292 MET A SD  1 Q8R3G1 UNP 292 M 
ATOM 2264 C CE  . MET A 1 292 ? -30.110 -29.066 -19.537 1.0 65.48 ? 292 MET A CE  1 Q8R3G1 UNP 292 M 
ATOM 2265 N N   . PRO A 1 293 ? -27.801 -25.892 -23.283 1.0 62.13 ? 293 PRO A N   1 Q8R3G1 UNP 293 P 
ATOM 2266 C CA  . PRO A 1 293 ? -28.065 -24.538 -23.749 1.0 62.13 ? 293 PRO A CA  1 Q8R3G1 UNP 293 P 
ATOM 2267 C C   . PRO A 1 293 ? -28.900 -23.789 -22.700 1.0 62.13 ? 293 PRO A C   1 Q8R3G1 UNP 293 P 
ATOM 2268 C CB  . PRO A 1 293 ? -28.791 -24.723 -25.085 1.0 62.13 ? 293 PRO A CB  1 Q8R3G1 UNP 293 P 
ATOM 2269 O O   . PRO A 1 293 ? -30.032 -24.169 -22.407 1.0 62.13 ? 293 PRO A O   1 Q8R3G1 UNP 293 P 
ATOM 2270 C CG  . PRO A 1 293 ? -29.575 -26.023 -24.894 1.0 62.13 ? 293 PRO A CG  1 Q8R3G1 UNP 293 P 
ATOM 2271 C CD  . PRO A 1 293 ? -28.747 -26.824 -23.886 1.0 62.13 ? 293 PRO A CD  1 Q8R3G1 UNP 293 P 
ATOM 2272 N N   . TYR A 1 294 ? -28.352 -22.716 -22.128 1.0 65.58 ? 294 TYR A N   1 Q8R3G1 UNP 294 Y 
ATOM 2273 C CA  . TYR A 1 294 ? -29.142 -21.737 -21.377 1.0 65.58 ? 294 TYR A CA  1 Q8R3G1 UNP 294 Y 
ATOM 2274 C C   . TYR A 1 294 ? -29.818 -20.768 -22.365 1.0 65.58 ? 294 TYR A C   1 Q8R3G1 UNP 294 Y 
ATOM 2275 C CB  . TYR A 1 294 ? -28.265 -20.977 -20.370 1.0 65.58 ? 294 TYR A CB  1 Q8R3G1 UNP 294 Y 
ATOM 2276 O O   . TYR A 1 294 ? -29.132 -20.250 -23.250 1.0 65.58 ? 294 TYR A O   1 Q8R3G1 UNP 294 Y 
ATOM 2277 C CG  . TYR A 1 294 ? -28.201 -21.623 -19.000 1.0 65.58 ? 294 TYR A CG  1 Q8R3G1 UNP 294 Y 
ATOM 2278 C CD1 . TYR A 1 294 ? -29.128 -21.240 -18.009 1.0 65.58 ? 294 TYR A CD1 1 Q8R3G1 UNP 294 Y 
ATOM 2279 C CD2 . TYR A 1 294 ? -27.231 -22.603 -18.713 1.0 65.58 ? 294 TYR A CD2 1 Q8R3G1 UNP 294 Y 
ATOM 2280 C CE1 . TYR A 1 294 ? -29.084 -21.829 -16.730 1.0 65.58 ? 294 TYR A CE1 1 Q8R3G1 UNP 294 Y 
ATOM 2281 C CE2 . TYR A 1 294 ? -27.180 -23.190 -17.434 1.0 65.58 ? 294 TYR A CE2 1 Q8R3G1 UNP 294 Y 
ATOM 2282 O OH  . TYR A 1 294 ? -28.053 -23.373 -15.208 1.0 65.58 ? 294 TYR A OH  1 Q8R3G1 UNP 294 Y 
ATOM 2283 C CZ  . TYR A 1 294 ? -28.105 -22.804 -16.441 1.0 65.58 ? 294 TYR A CZ  1 Q8R3G1 UNP 294 Y 
ATOM 2284 N N   . PRO A 1 295 ? -31.131 -20.496 -22.238 1.0 62.34 ? 295 PRO A N   1 Q8R3G1 UNP 295 P 
ATOM 2285 C CA  . PRO A 1 295 ? -31.801 -19.498 -23.060 1.0 62.34 ? 295 PRO A CA  1 Q8R3G1 UNP 295 P 
ATOM 2286 C C   . PRO A 1 295 ? -31.332 -18.096 -22.652 1.0 62.34 ? 295 PRO A C   1 Q8R3G1 UNP 295 P 
ATOM 2287 C CB  . PRO A 1 295 ? -33.300 -19.728 -22.846 1.0 62.34 ? 295 PRO A CB  1 Q8R3G1 UNP 295 P 
ATOM 2288 O O   . PRO A 1 295 ? -31.412 -17.707 -21.487 1.0 62.34 ? 295 PRO A O   1 Q8R3G1 UNP 295 P 
ATOM 2289 C CG  . PRO A 1 295 ? -33.376 -20.320 -21.439 1.0 62.34 ? 295 PRO A CG  1 Q8R3G1 UNP 295 P 
ATOM 2290 C CD  . PRO A 1 295 ? -32.060 -21.082 -21.284 1.0 62.34 ? 295 PRO A CD  1 Q8R3G1 UNP 295 P 
ATOM 2291 N N   . ASN A 1 296 ? -30.814 -17.347 -23.624 1.0 59.26 ? 296 ASN A N   1 Q8R3G1 UNP 296 N 
ATOM 2292 C CA  . ASN A 1 296 ? -30.467 -15.937 -23.481 1.0 59.26 ? 296 ASN A CA  1 Q8R3G1 UNP 296 N 
ATOM 2293 C C   . ASN A 1 296 ? -31.763 -15.107 -23.368 1.0 59.26 ? 296 ASN A C   1 Q8R3G1 UNP 296 N 
ATOM 2294 C CB  . ASN A 1 296 ? -29.602 -15.551 -24.698 1.0 59.26 ? 296 ASN A CB  1 Q8R3G1 UNP 296 N 
ATOM 2295 O O   . ASN A 1 296 ? -32.641 -15.235 -24.216 1.0 59.26 ? 296 ASN A O   1 Q8R3G1 UNP 296 N 
ATOM 2296 C CG  . ASN A 1 296 ? -28.952 -14.185 -24.577 1.0 59.26 ? 296 ASN A CG  1 Q8R3G1 UNP 296 N 
ATOM 2297 N ND2 . ASN A 1 296 ? -28.409 -13.667 -25.652 1.0 59.26 ? 296 ASN A ND2 1 Q8R3G1 UNP 296 N 
ATOM 2298 O OD1 . ASN A 1 296 ? -28.910 -13.579 -23.520 1.0 59.26 ? 296 ASN A OD1 1 Q8R3G1 UNP 296 N 
ATOM 2299 N N   . LEU A 1 297 ? -31.887 -14.281 -22.326 1.0 50.19 ? 297 LEU A N   1 Q8R3G1 UNP 297 L 
ATOM 2300 C CA  . LEU A 1 297 ? -33.059 -13.437 -22.026 1.0 50.19 ? 297 LEU A CA  1 Q8R3G1 UNP 297 L 
ATOM 2301 C C   . LEU A 1 297 ? -32.819 -11.951 -22.366 1.0 50.19 ? 297 LEU A C   1 Q8R3G1 UNP 297 L 
ATOM 2302 C CB  . LEU A 1 297 ? -33.493 -13.639 -20.553 1.0 50.19 ? 297 LEU A CB  1 Q8R3G1 UNP 297 L 
ATOM 2303 O O   . LEU A 1 297 ? -33.325 -11.065 -21.679 1.0 50.19 ? 297 LEU A O   1 Q8R3G1 UNP 297 L 
ATOM 2304 C CG  . LEU A 1 297 ? -34.204 -14.965 -20.235 1.0 50.19 ? 297 LEU A CG  1 Q8R3G1 UNP 297 L 
ATOM 2305 C CD1 . LEU A 1 297 ? -34.421 -15.065 -18.722 1.0 50.19 ? 297 LEU A CD1 1 Q8R3G1 UNP 297 L 
ATOM 2306 C CD2 . LEU A 1 297 ? -35.577 -15.058 -20.908 1.0 50.19 ? 297 LEU A CD2 1 Q8R3G1 UNP 297 L 
ATOM 2307 N N   . ALA A 1 298 ? -32.034 -11.651 -23.401 1.0 55.74 ? 298 ALA A N   1 Q8R3G1 UNP 298 A 
ATOM 2308 C CA  . ALA A 1 298 ? -31.787 -10.274 -23.828 1.0 55.74 ? 298 ALA A CA  1 Q8R3G1 UNP 298 A 
ATOM 2309 C C   . ALA A 1 298 ? -32.672 -9.905  -25.036 1.0 55.74 ? 298 ALA A C   1 Q8R3G1 UNP 298 A 
ATOM 2310 C CB  . ALA A 1 298 ? -30.295 -10.096 -24.117 1.0 55.74 ? 298 ALA A CB  1 Q8R3G1 UNP 298 A 
ATOM 2311 O O   . ALA A 1 298 ? -32.675 -10.655 -26.012 1.0 55.74 ? 298 ALA A O   1 Q8R3G1 UNP 298 A 
ATOM 2312 N N   . PRO A 1 299 ? -33.408 -8.778  -25.001 1.0 61.12 ? 299 PRO A N   1 Q8R3G1 UNP 299 P 
ATOM 2313 C CA  . PRO A 1 299 ? -34.119 -8.271  -26.169 1.0 61.12 ? 299 PRO A CA  1 Q8R3G1 UNP 299 P 
ATOM 2314 C C   . PRO A 1 299 ? -33.123 -7.784  -27.232 1.0 61.12 ? 299 PRO A C   1 Q8R3G1 UNP 299 P 
ATOM 2315 C CB  . PRO A 1 299 ? -35.021 -7.149  -25.643 1.0 61.12 ? 299 PRO A CB  1 Q8R3G1 UNP 299 P 
ATOM 2316 O O   . PRO A 1 299 ? -32.174 -7.064  -26.916 1.0 61.12 ? 299 PRO A O   1 Q8R3G1 UNP 299 P 
ATOM 2317 C CG  . PRO A 1 299 ? -34.280 -6.638  -24.407 1.0 61.12 ? 299 PRO A CG  1 Q8R3G1 UNP 299 P 
ATOM 2318 C CD  . PRO A 1 299 ? -33.566 -7.877  -23.870 1.0 61.12 ? 299 PRO A CD  1 Q8R3G1 UNP 299 P 
ATOM 2319 N N   . ASP A 1 300 ? -33.354 -8.171  -28.486 1.0 53.53 ? 300 ASP A N   1 Q8R3G1 UNP 300 D 
ATOM 2320 C CA  . ASP A 1 300 ? -32.586 -7.716  -29.644 1.0 53.53 ? 300 ASP A CA  1 Q8R3G1 UNP 300 D 
ATOM 2321 C C   . ASP A 1 300 ? -32.734 -6.193  -29.817 1.0 53.53 ? 300 ASP A C   1 Q8R3G1 UNP 300 D 
ATOM 2322 C CB  . ASP A 1 300 ? -33.056 -8.469  -30.903 1.0 53.53 ? 300 ASP A CB  1 Q8R3G1 UNP 300 D 
ATOM 2323 O O   . ASP A 1 300 ? -33.830 -5.679  -30.043 1.0 53.53 ? 300 ASP A O   1 Q8R3G1 UNP 300 D 
ATOM 2324 C CG  . ASP A 1 300 ? -32.715 -9.963  -30.864 1.0 53.53 ? 300 ASP A CG  1 Q8R3G1 UNP 300 D 
ATOM 2325 O OD1 . ASP A 1 300 ? -31.509 -10.276 -30.737 1.0 53.53 ? 300 ASP A OD1 1 Q8R3G1 UNP 300 D 
ATOM 2326 O OD2 . ASP A 1 300 ? -33.661 -10.778 -30.957 1.0 53.53 ? 300 ASP A OD2 1 Q8R3G1 UNP 300 D 
ATOM 2327 N N   . VAL A 1 301 ? -31.625 -5.456  -29.696 1.0 64.31 ? 301 VAL A N   1 Q8R3G1 UNP 301 V 
ATOM 2328 C CA  . VAL A 1 301 ? -31.546 -4.034  -30.060 1.0 64.31 ? 301 VAL A CA  1 Q8R3G1 UNP 301 V 
ATOM 2329 C C   . VAL A 1 301 ? -30.917 -3.945  -31.444 1.0 64.31 ? 301 VAL A C   1 Q8R3G1 UNP 301 V 
ATOM 2330 C CB  . VAL A 1 301 ? -30.795 -3.192  -29.011 1.0 64.31 ? 301 VAL A CB  1 Q8R3G1 UNP 301 V 
ATOM 2331 O O   . VAL A 1 301 ? -29.729 -4.213  -31.623 1.0 64.31 ? 301 VAL A O   1 Q8R3G1 UNP 301 V 
ATOM 2332 C CG1 . VAL A 1 301 ? -30.623 -1.732  -29.460 1.0 64.31 ? 301 VAL A CG1 1 Q8R3G1 UNP 301 V 
ATOM 2333 C CG2 . VAL A 1 301 ? -31.564 -3.176  -27.682 1.0 64.31 ? 301 VAL A CG2 1 Q8R3G1 UNP 301 V 
ATOM 2334 N N   . ASP A 1 302 ? -31.747 -3.578  -32.414 1.0 48.09 ? 302 ASP A N   1 Q8R3G1 UNP 302 D 
ATOM 2335 C CA  . ASP A 1 302 ? -31.395 -3.400  -33.817 1.0 48.09 ? 302 ASP A CA  1 Q8R3G1 UNP 302 D 
ATOM 2336 C C   . ASP A 1 302 ? -30.450 -2.190  -33.973 1.0 48.09 ? 302 ASP A C   1 Q8R3G1 UNP 302 D 
ATOM 2337 C CB  . ASP A 1 302 ? -32.715 -3.263  -34.610 1.0 48.09 ? 302 ASP A CB  1 Q8R3G1 UNP 302 D 
ATOM 2338 O O   . ASP A 1 302 ? -30.815 -1.043  -33.704 1.0 48.09 ? 302 ASP A O   1 Q8R3G1 UNP 302 D 
ATOM 2339 C CG  . ASP A 1 302 ? -32.672 -3.810  -36.040 1.0 48.09 ? 302 ASP A CG  1 Q8R3G1 UNP 302 D 
ATOM 2340 O OD1 . ASP A 1 302 ? -31.609 -4.332  -36.446 1.0 48.09 ? 302 ASP A OD1 1 Q8R3G1 UNP 302 D 
ATOM 2341 O OD2 . ASP A 1 302 ? -33.721 -3.706  -36.713 1.0 48.09 ? 302 ASP A OD2 1 Q8R3G1 UNP 302 D 
ATOM 2342 N N   . LEU A 1 303 ? -29.194 -2.446  -34.347 1.0 48.59 ? 303 LEU A N   1 Q8R3G1 UNP 303 L 
ATOM 2343 C CA  . LEU A 1 303 ? -28.180 -1.421  -34.597 1.0 48.59 ? 303 LEU A CA  1 Q8R3G1 UNP 303 L 
ATOM 2344 C C   . LEU A 1 303 ? -28.183 -1.060  -36.084 1.0 48.59 ? 303 LEU A C   1 Q8R3G1 UNP 303 L 
ATOM 2345 C CB  . LEU A 1 303 ? -26.795 -1.915  -34.127 1.0 48.59 ? 303 LEU A CB  1 Q8R3G1 UNP 303 L 
ATOM 2346 O O   . LEU A 1 303 ? -27.520 -1.703  -36.897 1.0 48.59 ? 303 LEU A O   1 Q8R3G1 UNP 303 L 
ATOM 2347 C CG  . LEU A 1 303 ? -26.552 -1.787  -32.612 1.0 48.59 ? 303 LEU A CG  1 Q8R3G1 UNP 303 L 
ATOM 2348 C CD1 . LEU A 1 303 ? -25.380 -2.680  -32.200 1.0 48.59 ? 303 LEU A CD1 1 Q8R3G1 UNP 303 L 
ATOM 2349 C CD2 . LEU A 1 303 ? -26.197 -0.348  -32.218 1.0 48.59 ? 303 LEU A CD2 1 Q8R3G1 UNP 303 L 
ATOM 2350 N N   . THR A 1 304 ? -28.876 0.018   -36.443 1.0 50.14 ? 304 THR A N   1 Q8R3G1 UNP 304 T 
ATOM 2351 C CA  . THR A 1 304 ? -28.702 0.661   -37.751 1.0 50.14 ? 304 THR A CA  1 Q8R3G1 UNP 304 T 
ATOM 2352 C C   . THR A 1 304 ? -27.396 1.469   -37.775 1.0 50.14 ? 304 THR A C   1 Q8R3G1 UNP 304 T 
ATOM 2353 C CB  . THR A 1 304 ? -29.869 1.593   -38.093 1.0 50.14 ? 304 THR A CB  1 Q8R3G1 UNP 304 T 
ATOM 2354 O O   . THR A 1 304 ? -27.212 2.336   -36.913 1.0 50.14 ? 304 THR A O   1 Q8R3G1 UNP 304 T 
ATOM 2355 C CG2 . THR A 1 304 ? -31.174 0.826   -38.293 1.0 50.14 ? 304 THR A CG2 1 Q8R3G1 UNP 304 T 
ATOM 2356 O OG1 . THR A 1 304 ? -30.057 2.537   -37.063 1.0 50.14 ? 304 THR A OG1 1 Q8R3G1 UNP 304 T 
ATOM 2357 N N   . PRO A 1 305 ? -26.495 1.266   -38.751 1.0 51.46 ? 305 PRO A N   1 Q8R3G1 UNP 305 P 
ATOM 2358 C CA  . PRO A 1 305 ? -25.292 2.076   -38.884 1.0 51.46 ? 305 PRO A CA  1 Q8R3G1 UNP 305 P 
ATOM 2359 C C   . PRO A 1 305 ? -25.612 3.403   -39.588 1.0 51.46 ? 305 PRO A C   1 Q8R3G1 UNP 305 P 
ATOM 2360 C CB  . PRO A 1 305 ? -24.317 1.196   -39.673 1.0 51.46 ? 305 PRO A CB  1 Q8R3G1 UNP 305 P 
ATOM 2361 O O   . PRO A 1 305 ? -26.039 3.416   -40.740 1.0 51.46 ? 305 PRO A O   1 Q8R3G1 UNP 305 P 
ATOM 2362 C CG  . PRO A 1 305 ? -25.230 0.345   -40.559 1.0 51.46 ? 305 PRO A CG  1 Q8R3G1 UNP 305 P 
ATOM 2363 C CD  . PRO A 1 305 ? -26.521 0.209   -39.751 1.0 51.46 ? 305 PRO A CD  1 Q8R3G1 UNP 305 P 
ATOM 2364 N N   . VAL A 1 306 ? -25.351 4.530   -38.919 1.0 52.65 ? 306 VAL A N   1 Q8R3G1 UNP 306 V 
ATOM 2365 C CA  . VAL A 1 306 ? -25.288 5.856   -39.553 1.0 52.65 ? 306 VAL A CA  1 Q8R3G1 UNP 306 V 
ATOM 2366 C C   . VAL A 1 306 ? -23.818 6.249   -39.732 1.0 52.65 ? 306 VAL A C   1 Q8R3G1 UNP 306 V 
ATOM 2367 C CB  . VAL A 1 306 ? -26.104 6.919   -38.787 1.0 52.65 ? 306 VAL A CB  1 Q8R3G1 UNP 306 V 
ATOM 2368 O O   . VAL A 1 306 ? -23.113 6.585   -38.787 1.0 52.65 ? 306 VAL A O   1 Q8R3G1 UNP 306 V 
ATOM 2369 C CG1 . VAL A 1 306 ? -25.970 8.308   -39.429 1.0 52.65 ? 306 VAL A CG1 1 Q8R3G1 UNP 306 V 
ATOM 2370 C CG2 . VAL A 1 306 ? -27.598 6.561   -38.776 1.0 52.65 ? 306 VAL A CG2 1 Q8R3G1 UNP 306 V 
ATOM 2371 N N   . VAL A 1 307 ? -23.369 6.206   -40.981 1.0 49.66 ? 307 VAL A N   1 Q8R3G1 UNP 307 V 
ATOM 2372 C CA  . VAL A 1 307 ? -22.269 6.998   -41.568 1.0 49.66 ? 307 VAL A CA  1 Q8R3G1 UNP 307 V 
ATOM 2373 C C   . VAL A 1 307 ? -22.965 8.017   -42.495 1.0 49.66 ? 307 VAL A C   1 Q8R3G1 UNP 307 V 
ATOM 2374 C CB  . VAL A 1 307 ? -21.288 6.100   -42.380 1.0 49.66 ? 307 VAL A CB  1 Q8R3G1 UNP 307 V 
ATOM 2375 O O   . VAL A 1 307 ? -24.065 7.687   -42.943 1.0 49.66 ? 307 VAL A O   1 Q8R3G1 UNP 307 V 
ATOM 2376 C CG1 . VAL A 1 307 ? -19.848 6.232   -41.870 1.0 49.66 ? 307 VAL A CG1 1 Q8R3G1 UNP 307 V 
ATOM 2377 C CG2 . VAL A 1 307 ? -21.616 4.595   -42.395 1.0 49.66 ? 307 VAL A CG2 1 Q8R3G1 UNP 307 V 
ATOM 2378 N N   . PRO A 1 308 ? -22.412 9.187   -42.891 1.0 43.38 ? 308 PRO A N   1 Q8R3G1 UNP 308 P 
ATOM 2379 C CA  . PRO A 1 308 ? -21.059 9.721   -42.685 1.0 43.38 ? 308 PRO A CA  1 Q8R3G1 UNP 308 P 
ATOM 2380 C C   . PRO A 1 308 ? -21.001 11.251  -42.409 1.0 43.38 ? 308 PRO A C   1 Q8R3G1 UNP 308 P 
ATOM 2381 C CB  . PRO A 1 308 ? -20.442 9.469   -44.066 1.0 43.38 ? 308 PRO A CB  1 Q8R3G1 UNP 308 P 
ATOM 2382 O O   . PRO A 1 308 ? -21.964 11.981  -42.621 1.0 43.38 ? 308 PRO A O   1 Q8R3G1 UNP 308 P 
ATOM 2383 C CG  . PRO A 1 308 ? -21.596 9.799   -45.028 1.0 43.38 ? 308 PRO A CG  1 Q8R3G1 UNP 308 P 
ATOM 2384 C CD  . PRO A 1 308 ? -22.862 9.713   -44.179 1.0 43.38 ? 308 PRO A CD  1 Q8R3G1 UNP 308 P 
ATOM 2385 N N   . SER A 1 309 ? -19.828 11.775  -42.044 1.0 43.01 ? 309 SER A N   1 Q8R3G1 UNP 309 S 
ATOM 2386 C CA  . SER A 1 309 ? -19.205 12.942  -42.710 1.0 43.01 ? 309 SER A CA  1 Q8R3G1 UNP 309 S 
ATOM 2387 C C   . SER A 1 309 ? -17.969 13.387  -41.940 1.0 43.01 ? 309 SER A C   1 Q8R3G1 UNP 309 S 
ATOM 2388 C CB  . SER A 1 309 ? -20.107 14.172  -42.891 1.0 43.01 ? 309 SER A CB  1 Q8R3G1 UNP 309 S 
ATOM 2389 O O   . SER A 1 309 ? -18.047 13.863  -40.810 1.0 43.01 ? 309 SER A O   1 Q8R3G1 UNP 309 S 
ATOM 2390 O OG  . SER A 1 309 ? -20.853 13.995  -44.075 1.0 43.01 ? 309 SER A OG  1 Q8R3G1 UNP 309 S 
ATOM 2391 N N   . ALA A 1 310 ? -16.815 13.238  -42.582 1.0 41.88 ? 310 ALA A N   1 Q8R3G1 UNP 310 A 
ATOM 2392 C CA  . ALA A 1 310 ? -15.578 13.855  -42.147 1.0 41.88 ? 310 ALA A CA  1 Q8R3G1 UNP 310 A 
ATOM 2393 C C   . ALA A 1 310 ? -15.647 15.363  -42.427 1.0 41.88 ? 310 ALA A C   1 Q8R3G1 UNP 310 A 
ATOM 2394 C CB  . ALA A 1 310 ? -14.421 13.179  -42.894 1.0 41.88 ? 310 ALA A CB  1 Q8R3G1 UNP 310 A 
ATOM 2395 O O   . ALA A 1 310 ? -15.821 15.774  -43.572 1.0 41.88 ? 310 ALA A O   1 Q8R3G1 UNP 310 A 
ATOM 2396 N N   . VAL A 1 311 ? -15.472 16.183  -41.391 1.0 47.33 ? 311 VAL A N   1 Q8R3G1 UNP 311 V 
ATOM 2397 C CA  . VAL A 1 311 ? -15.135 17.601  -41.541 1.0 47.33 ? 311 VAL A CA  1 Q8R3G1 UNP 311 V 
ATOM 2398 C C   . VAL A 1 311 ? -13.654 17.737  -41.213 1.0 47.33 ? 311 VAL A C   1 Q8R3G1 UNP 311 V 
ATOM 2399 C CB  . VAL A 1 311 ? -16.028 18.517  -40.683 1.0 47.33 ? 311 VAL A CB  1 Q8R3G1 UNP 311 V 
ATOM 2400 O O   . VAL A 1 311 ? -13.240 17.605  -40.063 1.0 47.33 ? 311 VAL A O   1 Q8R3G1 UNP 311 V 
ATOM 2401 C CG1 . VAL A 1 311 ? -15.685 19.995  -40.920 1.0 47.33 ? 311 VAL A CG1 1 Q8R3G1 UNP 311 V 
ATOM 2402 C CG2 . VAL A 1 311 ? -17.510 18.323  -41.035 1.0 47.33 ? 311 VAL A CG2 1 Q8R3G1 UNP 311 V 
ATOM 2403 N N   . ALA A 1 312 ? -12.848 17.945  -42.251 1.0 43.50 ? 312 ALA A N   1 Q8R3G1 UNP 312 A 
ATOM 2404 C CA  . ALA A 1 312 ? -11.453 18.330  -42.119 1.0 43.50 ? 312 ALA A CA  1 Q8R3G1 UNP 312 A 
ATOM 2405 C C   . ALA A 1 312 ? -11.383 19.803  -41.692 1.0 43.50 ? 312 ALA A C   1 Q8R3G1 UNP 312 A 
ATOM 2406 C CB  . ALA A 1 312 ? -10.750 18.083  -43.461 1.0 43.50 ? 312 ALA A CB  1 Q8R3G1 UNP 312 A 
ATOM 2407 O O   . ALA A 1 312 ? -11.940 20.668  -42.366 1.0 43.50 ? 312 ALA A O   1 Q8R3G1 UNP 312 A 
ATOM 2408 N N   . ILE A 1 313 ? -10.688 20.092  -40.592 1.0 51.12 ? 313 ILE A N   1 Q8R3G1 UNP 313 I 
ATOM 2409 C CA  . ILE A 1 313 ? -10.380 21.458  -40.161 1.0 51.12 ? 313 ILE A CA  1 Q8R3G1 UNP 313 I 
ATOM 2410 C C   . ILE A 1 313 ? -8.858  21.605  -40.154 1.0 51.12 ? 313 ILE A C   1 Q8R3G1 UNP 313 I 
ATOM 2411 C CB  . ILE A 1 313 ? -11.036 21.855  -38.808 1.0 51.12 ? 313 ILE A CB  1 Q8R3G1 UNP 313 I 
ATOM 2412 O O   . ILE A 1 313 ? -8.168  21.049  -39.302 1.0 51.12 ? 313 ILE A O   1 Q8R3G1 UNP 313 I 
ATOM 2413 C CG1 . ILE A 1 313 ? -12.201 20.935  -38.367 1.0 51.12 ? 313 ILE A CG1 1 Q8R3G1 UNP 313 I 
ATOM 2414 C CG2 . ILE A 1 313 ? -11.504 23.319  -38.922 1.0 51.12 ? 313 ILE A CG2 1 Q8R3G1 UNP 313 I 
ATOM 2415 C CD1 . ILE A 1 313 ? -12.775 21.265  -36.984 1.0 51.12 ? 313 ILE A CD1 1 Q8R3G1 UNP 313 I 
ATOM 2416 N N   . ASN A 1 314 ? -8.342  22.320  -41.155 1.0 51.20 ? 314 ASN A N   1 Q8R3G1 UNP 314 N 
ATOM 2417 C CA  . ASN A 1 314 ? -6.957  22.784  -41.219 1.0 51.20 ? 314 ASN A CA  1 Q8R3G1 UNP 314 N 
ATOM 2418 C C   . ASN A 1 314 ? -6.745  23.919  -40.201 1.0 51.20 ? 314 ASN A C   1 Q8R3G1 UNP 314 N 
ATOM 2419 C CB  . ASN A 1 314 ? -6.664  23.324  -42.639 1.0 51.20 ? 314 ASN A CB  1 Q8R3G1 UNP 314 N 
ATOM 2420 O O   . ASN A 1 314 ? -7.558  24.845  -40.173 1.0 51.20 ? 314 ASN A O   1 Q8R3G1 UNP 314 N 
ATOM 2421 C CG  . ASN A 1 314 ? -6.002  22.337  -43.579 1.0 51.20 ? 314 ASN A CG  1 Q8R3G1 UNP 314 N 
ATOM 2422 N ND2 . ASN A 1 314 ? -5.934  22.661  -44.849 1.0 51.20 ? 314 ASN A ND2 1 Q8R3G1 UNP 314 N 
ATOM 2423 O OD1 . ASN A 1 314 ? -5.506  21.292  -43.200 1.0 51.20 ? 314 ASN A OD1 1 Q8R3G1 UNP 314 N 
ATOM 2424 N N   . PRO A 1 315 ? -5.642  23.935  -39.433 1.0 53.40 ? 315 PRO A N   1 Q8R3G1 UNP 315 P 
ATOM 2425 C CA  . PRO A 1 315 ? -5.249  25.100  -38.657 1.0 53.40 ? 315 PRO A CA  1 Q8R3G1 UNP 315 P 
ATOM 2426 C C   . PRO A 1 315 ? -4.288  25.981  -39.472 1.0 53.40 ? 315 PRO A C   1 Q8R3G1 UNP 315 P 
ATOM 2427 C CB  . PRO A 1 315 ? -4.617  24.512  -37.394 1.0 53.40 ? 315 PRO A CB  1 Q8R3G1 UNP 315 P 
ATOM 2428 O O   . PRO A 1 315 ? -3.176  25.572  -39.801 1.0 53.40 ? 315 PRO A O   1 Q8R3G1 UNP 315 P 
ATOM 2429 C CG  . PRO A 1 315 ? -3.975  23.207  -37.877 1.0 53.40 ? 315 PRO A CG  1 Q8R3G1 UNP 315 P 
ATOM 2430 C CD  . PRO A 1 315 ? -4.767  22.810  -39.128 1.0 53.40 ? 315 PRO A CD  1 Q8R3G1 UNP 315 P 
ATOM 2431 N N   . THR A 1 316 ? -4.690  27.215  -39.779 1.0 55.46 ? 316 THR A N   1 Q8R3G1 UNP 316 T 
ATOM 2432 C CA  . THR A 1 316 ? -3.773  28.289  -40.204 1.0 55.46 ? 316 THR A CA  1 Q8R3G1 UNP 316 T 
ATOM 2433 C C   . THR A 1 316 ? -3.335  29.108  -38.985 1.0 55.46 ? 316 THR A C   1 Q8R3G1 UNP 316 T 
ATOM 2434 C CB  . THR A 1 316 ? -4.416  29.238  -41.226 1.0 55.46 ? 316 THR A CB  1 Q8R3G1 UNP 316 T 
ATOM 2435 O O   . THR A 1 316 ? -4.207  29.574  -38.247 1.0 55.46 ? 316 THR A O   1 Q8R3G1 UNP 316 T 
ATOM 2436 C CG2 . THR A 1 316 ? -4.425  28.637  -42.628 1.0 55.46 ? 316 THR A CG2 1 Q8R3G1 UNP 316 T 
ATOM 2437 O OG1 . THR A 1 316 ? -5.747  29.527  -40.862 1.0 55.46 ? 316 THR A OG1 1 Q8R3G1 UNP 316 T 
ATOM 2438 N N   . PRO A 1 317 ? -2.027  29.334  -38.759 1.0 50.48 ? 317 PRO A N   1 Q8R3G1 UNP 317 P 
ATOM 2439 C CA  . PRO A 1 317 ? -1.542  30.180  -37.676 1.0 50.48 ? 317 PRO A CA  1 Q8R3G1 UNP 317 P 
ATOM 2440 C C   . PRO A 1 317 ? -1.447  31.638  -38.145 1.0 50.48 ? 317 PRO A C   1 Q8R3G1 UNP 317 P 
ATOM 2441 C CB  . PRO A 1 317 ? -0.180  29.586  -37.312 1.0 50.48 ? 317 PRO A CB  1 Q8R3G1 UNP 317 P 
ATOM 2442 O O   . PRO A 1 317 ? -0.837  31.920  -39.174 1.0 50.48 ? 317 PRO A O   1 Q8R3G1 UNP 317 P 
ATOM 2443 C CG  . PRO A 1 317 ? 0.354   29.069  -38.651 1.0 50.48 ? 317 PRO A CG  1 Q8R3G1 UNP 317 P 
ATOM 2444 C CD  . PRO A 1 317 ? -0.899  28.740  -39.466 1.0 50.48 ? 317 PRO A CD  1 Q8R3G1 UNP 317 P 
ATOM 2445 N N   . ASN A 1 318 ? -2.016  32.571  -37.379 1.0 49.35 ? 318 ASN A N   1 Q8R3G1 UNP 318 N 
ATOM 2446 C CA  . ASN A 1 318 ? -1.835  34.008  -37.592 1.0 49.35 ? 318 ASN A CA  1 Q8R3G1 UNP 318 N 
ATOM 2447 C C   . ASN A 1 318 ? -0.944  34.571  -36.467 1.0 49.35 ? 318 ASN A C   1 Q8R3G1 UNP 318 N 
ATOM 2448 C CB  . ASN A 1 318 ? -3.215  34.699  -37.674 1.0 49.35 ? 318 ASN A CB  1 Q8R3G1 UNP 318 N 
ATOM 2449 O O   . ASN A 1 318 ? -1.286  34.384  -35.296 1.0 49.35 ? 318 ASN A O   1 Q8R3G1 UNP 318 N 
ATOM 2450 C CG  . ASN A 1 318 ? -3.314  35.717  -38.800 1.0 49.35 ? 318 ASN A CG  1 Q8R3G1 UNP 318 N 
ATOM 2451 N ND2 . ASN A 1 318 ? -4.177  36.697  -38.677 1.0 49.35 ? 318 ASN A ND2 1 Q8R3G1 UNP 318 N 
ATOM 2452 O OD1 . ASN A 1 318 ? -2.653  35.637  -39.818 1.0 49.35 ? 318 ASN A OD1 1 Q8R3G1 UNP 318 N 
ATOM 2453 N N   . PRO A 1 319 ? 0.185   35.240  -36.766 1.0 42.12 ? 319 PRO A N   1 Q8R3G1 UNP 319 P 
ATOM 2454 C CA  . PRO A 1 319 ? 1.033   35.859  -35.758 1.0 42.12 ? 319 PRO A CA  1 Q8R3G1 UNP 319 P 
ATOM 2455 C C   . PRO A 1 319 ? 0.632   37.328  -35.570 1.0 42.12 ? 319 PRO A C   1 Q8R3G1 UNP 319 P 
ATOM 2456 C CB  . PRO A 1 319 ? 2.450   35.697  -36.315 1.0 42.12 ? 319 PRO A CB  1 Q8R3G1 UNP 319 P 
ATOM 2457 O O   . PRO A 1 319 ? 0.608   38.095  -36.529 1.0 42.12 ? 319 PRO A O   1 Q8R3G1 UNP 319 P 
ATOM 2458 C CG  . PRO A 1 319 ? 2.257   35.811  -37.831 1.0 42.12 ? 319 PRO A CG  1 Q8R3G1 UNP 319 P 
ATOM 2459 C CD  . PRO A 1 319 ? 0.817   35.348  -38.076 1.0 42.12 ? 319 PRO A CD  1 Q8R3G1 UNP 319 P 
ATOM 2460 N N   . ALA A 1 320 ? 0.351   37.753  -34.338 1.0 44.76 ? 320 ALA A N   1 Q8R3G1 UNP 320 A 
ATOM 2461 C CA  . ALA A 1 320 ? 0.238   39.173  -34.011 1.0 44.76 ? 320 ALA A CA  1 Q8R3G1 UNP 320 A 
ATOM 2462 C C   . ALA A 1 320 ? 0.732   39.457  -32.584 1.0 44.76 ? 320 ALA A C   1 Q8R3G1 UNP 320 A 
ATOM 2463 C CB  . ALA A 1 320 ? -1.189  39.671  -34.261 1.0 44.76 ? 320 ALA A CB  1 Q8R3G1 UNP 320 A 
ATOM 2464 O O   . ALA A 1 320 ? 0.035   39.228  -31.604 1.0 44.76 ? 320 ALA A O   1 Q8R3G1 UNP 320 A 
ATOM 2465 N N   . VAL A 1 321 ? 1.989   39.900  -32.540 1.0 46.29 ? 321 VAL A N   1 Q8R3G1 UNP 321 V 
ATOM 2466 C CA  . VAL A 1 321 ? 2.529   41.070  -31.826 1.0 46.29 ? 321 VAL A CA  1 Q8R3G1 UNP 321 V 
ATOM 2467 C C   . VAL A 1 321 ? 2.148   41.296  -30.349 1.0 46.29 ? 321 VAL A C   1 Q8R3G1 UNP 321 V 
ATOM 2468 C CB  . VAL A 1 321 ? 2.344   42.342  -32.681 1.0 46.29 ? 321 VAL A CB  1 Q8R3G1 UNP 321 V 
ATOM 2469 O O   . VAL A 1 321 ? 1.020   41.576  -29.967 1.0 46.29 ? 321 VAL A O   1 Q8R3G1 UNP 321 V 
ATOM 2470 C CG1 . VAL A 1 321 ? 3.083   43.547  -32.088 1.0 46.29 ? 321 VAL A CG1 1 Q8R3G1 UNP 321 V 
ATOM 2471 C CG2 . VAL A 1 321 ? 2.908   42.135  -34.101 1.0 46.29 ? 321 VAL A CG2 1 Q8R3G1 UNP 321 V 
ATOM 2472 N N   . TYR A 1 322 ? 3.223   41.271  -29.566 1.0 38.27 ? 322 TYR A N   1 Q8R3G1 UNP 322 Y 
ATOM 2473 C CA  . TYR A 1 322 ? 3.459   41.645  -28.175 1.0 38.27 ? 322 TYR A CA  1 Q8R3G1 UNP 322 Y 
ATOM 2474 C C   . TYR A 1 322 ? 3.084   43.099  -27.815 1.0 38.27 ? 322 TYR A C   1 Q8R3G1 UNP 322 Y 
ATOM 2475 C CB  . TYR A 1 322 ? 4.986   41.455  -28.073 1.0 38.27 ? 322 TYR A CB  1 Q8R3G1 UNP 322 Y 
ATOM 2476 O O   . TYR A 1 322 ? 3.425   44.021  -28.552 1.0 38.27 ? 322 TYR A O   1 Q8R3G1 UNP 322 Y 
ATOM 2477 C CG  . TYR A 1 322 ? 5.676   41.685  -26.751 1.0 38.27 ? 322 TYR A CG  1 Q8R3G1 UNP 322 Y 
ATOM 2478 C CD1 . TYR A 1 322 ? 6.345   42.899  -26.506 1.0 38.27 ? 322 TYR A CD1 1 Q8R3G1 UNP 322 Y 
ATOM 2479 C CD2 . TYR A 1 322 ? 5.782   40.622  -25.836 1.0 38.27 ? 322 TYR A CD2 1 Q8R3G1 UNP 322 Y 
ATOM 2480 C CE1 . TYR A 1 322 ? 7.132   43.046  -25.348 1.0 38.27 ? 322 TYR A CE1 1 Q8R3G1 UNP 322 Y 
ATOM 2481 C CE2 . TYR A 1 322 ? 6.553   40.773  -24.670 1.0 38.27 ? 322 TYR A CE2 1 Q8R3G1 UNP 322 Y 
ATOM 2482 O OH  . TYR A 1 322 ? 7.979   42.114  -23.299 1.0 38.27 ? 322 TYR A OH  1 Q8R3G1 UNP 322 Y 
ATOM 2483 C CZ  . TYR A 1 322 ? 7.231   41.984  -24.424 1.0 38.27 ? 322 TYR A CZ  1 Q8R3G1 UNP 322 Y 
ATOM 2484 N N   . ASN A 1 323 ? 2.510   43.308  -26.624 1.0 47.44 ? 323 ASN A N   1 Q8R3G1 UNP 323 N 
ATOM 2485 C CA  . ASN A 1 323 ? 2.672   44.545  -25.851 1.0 47.44 ? 323 ASN A CA  1 Q8R3G1 UNP 323 N 
ATOM 2486 C C   . ASN A 1 323 ? 2.707   44.205  -24.340 1.0 47.44 ? 323 ASN A C   1 Q8R3G1 UNP 323 N 
ATOM 2487 C CB  . ASN A 1 323 ? 1.559   45.554  -26.187 1.0 47.44 ? 323 ASN A CB  1 Q8R3G1 UNP 323 N 
ATOM 2488 O O   . ASN A 1 323 ? 1.797   43.511  -23.878 1.0 47.44 ? 323 ASN A O   1 Q8R3G1 UNP 323 N 
ATOM 2489 C CG  . ASN A 1 323 ? 1.959   46.961  -25.769 1.0 47.44 ? 323 ASN A CG  1 Q8R3G1 UNP 323 N 
ATOM 2490 N ND2 . ASN A 1 323 ? 1.125   47.675  -25.054 1.0 47.44 ? 323 ASN A ND2 1 Q8R3G1 UNP 323 N 
ATOM 2491 O OD1 . ASN A 1 323 ? 3.040   47.431  -26.074 1.0 47.44 ? 323 ASN A OD1 1 Q8R3G1 UNP 323 N 
ATOM 2492 N N   . PRO A 1 324 ? 3.734   44.623  -23.574 1.0 41.46 ? 324 PRO A N   1 Q8R3G1 UNP 324 P 
ATOM 2493 C CA  . PRO A 1 324 ? 3.877   44.307  -22.154 1.0 41.46 ? 324 PRO A CA  1 Q8R3G1 UNP 324 P 
ATOM 2494 C C   . PRO A 1 324 ? 3.284   45.408  -21.251 1.0 41.46 ? 324 PRO A C   1 Q8R3G1 UNP 324 P 
ATOM 2495 C CB  . PRO A 1 324 ? 5.389   44.154  -21.974 1.0 41.46 ? 324 PRO A CB  1 Q8R3G1 UNP 324 P 
ATOM 2496 O O   . PRO A 1 324 ? 2.896   46.467  -21.728 1.0 41.46 ? 324 PRO A O   1 Q8R3G1 UNP 324 P 
ATOM 2497 C CG  . PRO A 1 324 ? 5.938   45.255  -22.883 1.0 41.46 ? 324 PRO A CG  1 Q8R3G1 UNP 324 P 
ATOM 2498 C CD  . PRO A 1 324 ? 4.916   45.351  -24.020 1.0 41.46 ? 324 PRO A CD  1 Q8R3G1 UNP 324 P 
ATOM 2499 N N   . GLU A 1 325 ? 3.278   45.144  -19.940 1.0 41.15 ? 325 GLU A N   1 Q8R3G1 UNP 325 E 
ATOM 2500 C CA  . GLU A 1 325 ? 2.947   46.060  -18.827 1.0 41.15 ? 325 GLU A CA  1 Q8R3G1 UNP 325 E 
ATOM 2501 C C   . GLU A 1 325 ? 1.461   46.311  -18.514 1.0 41.15 ? 325 GLU A C   1 Q8R3G1 UNP 325 E 
ATOM 2502 C CB  . GLU A 1 325 ? 3.765   47.367  -18.860 1.0 41.15 ? 325 GLU A CB  1 Q8R3G1 UNP 325 E 
ATOM 2503 O O   . GLU A 1 325 ? 0.842   47.268  -18.961 1.0 41.15 ? 325 GLU A O   1 Q8R3G1 UNP 325 E 
ATOM 2504 C CG  . GLU A 1 325 ? 5.226   47.108  -18.493 1.0 41.15 ? 325 GLU A CG  1 Q8R3G1 UNP 325 E 
ATOM 2505 C CD  . GLU A 1 325 ? 6.086   48.352  -18.723 1.0 41.15 ? 325 GLU A CD  1 Q8R3G1 UNP 325 E 
ATOM 2506 O OE1 . GLU A 1 325 ? 6.440   49.006  -17.717 1.0 41.15 ? 325 GLU A OE1 1 Q8R3G1 UNP 325 E 
ATOM 2507 O OE2 . GLU A 1 325 ? 6.408   48.604  -19.904 1.0 41.15 ? 325 GLU A OE2 1 Q8R3G1 UNP 325 E 
ATOM 2508 N N   . ALA A 1 326 ? 0.929   45.492  -17.601 1.0 41.87 ? 326 ALA A N   1 Q8R3G1 UNP 326 A 
ATOM 2509 C CA  . ALA A 1 326 ? 0.147   45.949  -16.446 1.0 41.87 ? 326 ALA A CA  1 Q8R3G1 UNP 326 A 
ATOM 2510 C C   . ALA A 1 326 ? 0.008   44.781  -15.455 1.0 41.87 ? 326 ALA A C   1 Q8R3G1 UNP 326 A 
ATOM 2511 C CB  . ALA A 1 326 ? -1.227  46.498  -16.855 1.0 41.87 ? 326 ALA A CB  1 Q8R3G1 UNP 326 A 
ATOM 2512 O O   . ALA A 1 326 ? -0.871  43.928  -15.570 1.0 41.87 ? 326 ALA A O   1 Q8R3G1 UNP 326 A 
ATOM 2513 N N   . VAL A 1 327 ? 0.921   44.725  -14.486 1.0 43.29 ? 327 VAL A N   1 Q8R3G1 UNP 327 V 
ATOM 2514 C CA  . VAL A 1 327 ? 0.884   43.789  -13.357 1.0 43.29 ? 327 VAL A CA  1 Q8R3G1 UNP 327 V 
ATOM 2515 C C   . VAL A 1 327 ? -0.308  44.167  -12.470 1.0 43.29 ? 327 VAL A C   1 Q8R3G1 UNP 327 V 
ATOM 2516 C CB  . VAL A 1 327 ? 2.220   43.852  -12.580 1.0 43.29 ? 327 VAL A CB  1 Q8R3G1 UNP 327 V 
ATOM 2517 O O   . VAL A 1 327 ? -0.290  45.209  -11.821 1.0 43.29 ? 327 VAL A O   1 Q8R3G1 UNP 327 V 
ATOM 2518 C CG1 . VAL A 1 327 ? 2.268   42.836  -11.433 1.0 43.29 ? 327 VAL A CG1 1 Q8R3G1 UNP 327 V 
ATOM 2519 C CG2 . VAL A 1 327 ? 3.418   43.572  -13.502 1.0 43.29 ? 327 VAL A CG2 1 Q8R3G1 UNP 327 V 
ATOM 2520 N N   . ASN A 1 328 ? -1.362  43.349  -12.460 1.0 42.37 ? 328 ASN A N   1 Q8R3G1 UNP 328 N 
ATOM 2521 C CA  . ASN A 1 328 ? -2.509  43.504  -11.562 1.0 42.37 ? 328 ASN A CA  1 Q8R3G1 UNP 328 N 
ATOM 2522 C C   . ASN A 1 328 ? -2.731  42.185  -10.805 1.0 42.37 ? 328 ASN A C   1 Q8R3G1 UNP 328 N 
ATOM 2523 C CB  . ASN A 1 328 ? -3.731  44.003  -12.357 1.0 42.37 ? 328 ASN A CB  1 Q8R3G1 UNP 328 N 
ATOM 2524 O O   . ASN A 1 328 ? -3.198  41.195  -11.368 1.0 42.37 ? 328 ASN A O   1 Q8R3G1 UNP 328 N 
ATOM 2525 C CG  . ASN A 1 328 ? -4.756  44.709  -11.478 1.0 42.37 ? 328 ASN A CG  1 Q8R3G1 UNP 328 N 
ATOM 2526 N ND2 . ASN A 1 328 ? -5.245  45.849  -11.908 1.0 42.37 ? 328 ASN A ND2 1 Q8R3G1 UNP 328 N 
ATOM 2527 O OD1 . ASN A 1 328 ? -5.130  44.277  -10.401 1.0 42.37 ? 328 ASN A OD1 1 Q8R3G1 UNP 328 N 
ATOM 2528 N N   . GLU A 1 329 ? -2.308  42.171  -9.540  1.0 47.08 ? 329 GLU A N   1 Q8R3G1 UNP 329 E 
ATOM 2529 C CA  . GLU A 1 329 ? -2.426  41.053  -8.599  1.0 47.08 ? 329 GLU A CA  1 Q8R3G1 UNP 329 E 
ATOM 2530 C C   . GLU A 1 329 ? -3.887  40.594  -8.409  1.0 47.08 ? 329 GLU A C   1 Q8R3G1 UNP 329 E 
ATOM 2531 C CB  . GLU A 1 329 ? -1.926  41.494  -7.212  1.0 47.08 ? 329 GLU A CB  1 Q8R3G1 UNP 329 E 
ATOM 2532 O O   . GLU A 1 329 ? -4.773  41.419  -8.152  1.0 47.08 ? 329 GLU A O   1 Q8R3G1 UNP 329 E 
ATOM 2533 C CG  . GLU A 1 329 ? -0.408  41.640  -7.058  1.0 47.08 ? 329 GLU A CG  1 Q8R3G1 UNP 329 E 
ATOM 2534 C CD  . GLU A 1 329 ? -0.056  42.149  -5.649  1.0 47.08 ? 329 GLU A CD  1 Q8R3G1 UNP 329 E 
ATOM 2535 O OE1 . GLU A 1 329 ? 0.721   41.463  -4.947  1.0 47.08 ? 329 GLU A OE1 1 Q8R3G1 UNP 329 E 
ATOM 2536 O OE2 . GLU A 1 329 ? -0.617  43.196  -5.253  1.0 47.08 ? 329 GLU A OE2 1 Q8R3G1 UNP 329 E 
ATOM 2537 N N   . PRO A 1 330 ? -4.177  39.279  -8.403  1.0 56.11 ? 330 PRO A N   1 Q8R3G1 UNP 330 P 
ATOM 2538 C CA  . PRO A 1 330 ? -5.483  38.794  -7.995  1.0 56.11 ? 330 PRO A CA  1 Q8R3G1 UNP 330 P 
ATOM 2539 C C   . PRO A 1 330 ? -5.622  38.805  -6.463  1.0 56.11 ? 330 PRO A C   1 Q8R3G1 UNP 330 P 
ATOM 2540 C CB  . PRO A 1 330 ? -5.645  37.424  -8.643  1.0 56.11 ? 330 PRO A CB  1 Q8R3G1 UNP 330 P 
ATOM 2541 O O   . PRO A 1 330 ? -4.927  38.125  -5.709  1.0 56.11 ? 330 PRO A O   1 Q8R3G1 UNP 330 P 
ATOM 2542 C CG  . PRO A 1 330 ? -4.209  36.916  -8.747  1.0 56.11 ? 330 PRO A CG  1 Q8R3G1 UNP 330 P 
ATOM 2543 C CD  . PRO A 1 330 ? -3.350  38.179  -8.872  1.0 56.11 ? 330 PRO A CD  1 Q8R3G1 UNP 330 P 
ATOM 2544 N N   . LYS A 1 331 ? -6.584  39.622  -6.040  1.0 52.45 ? 331 LYS A N   1 Q8R3G1 UNP 331 K 
ATOM 2545 C CA  . LYS A 1 331 ? -7.076  39.929  -4.693  1.0 52.45 ? 331 LYS A CA  1 Q8R3G1 UNP 331 K 
ATOM 2546 C C   . LYS A 1 331 ? -7.261  38.713  -3.765  1.0 52.45 ? 331 LYS A C   1 Q8R3G1 UNP 331 K 
ATOM 2547 C CB  . LYS A 1 331 ? -8.411  40.675  -4.883  1.0 52.45 ? 331 LYS A CB  1 Q8R3G1 UNP 331 K 
ATOM 2548 O O   . LYS A 1 331 ? -7.843  37.690  -4.119  1.0 52.45 ? 331 LYS A O   1 Q8R3G1 UNP 331 K 
ATOM 2549 C CG  . LYS A 1 331 ? -8.224  42.052  -5.554  1.0 52.45 ? 331 LYS A CG  1 Q8R3G1 UNP 331 K 
ATOM 2550 C CD  . LYS A 1 331 ? -9.533  42.602  -6.137  1.0 52.45 ? 331 LYS A CD  1 Q8R3G1 UNP 331 K 
ATOM 2551 C CE  . LYS A 1 331 ? -9.264  43.977  -6.764  1.0 52.45 ? 331 LYS A CE  1 Q8R3G1 UNP 331 K 
ATOM 2552 N NZ  . LYS A 1 331 ? -10.434 44.489  -7.523  1.0 52.45 ? 331 LYS A NZ  1 Q8R3G1 UNP 331 K 
ATOM 2553 N N   . LYS A 1 332 ? -6.838  38.920  -2.512  1.0 50.10 ? 332 LYS A N   1 Q8R3G1 UNP 332 K 
ATOM 2554 C CA  . LYS A 1 332 ? -6.977  38.057  -1.326  1.0 50.10 ? 332 LYS A CA  1 Q8R3G1 UNP 332 K 
ATOM 2555 C C   . LYS A 1 332 ? -8.425  37.586  -1.102  1.0 50.10 ? 332 LYS A C   1 Q8R3G1 UNP 332 K 
ATOM 2556 C CB  . LYS A 1 332 ? -6.494  38.859  -0.095  1.0 50.10 ? 332 LYS A CB  1 Q8R3G1 UNP 332 K 
ATOM 2557 O O   . LYS A 1 332 ? -9.342  38.404  -1.033  1.0 50.10 ? 332 LYS A O   1 Q8R3G1 UNP 332 K 
ATOM 2558 C CG  . LYS A 1 332 ? -4.998  39.228  -0.156  1.0 50.10 ? 332 LYS A CG  1 Q8R3G1 UNP 332 K 
ATOM 2559 C CD  . LYS A 1 332 ? -4.572  40.204  0.955   1.0 50.10 ? 332 LYS A CD  1 Q8R3G1 UNP 332 K 
ATOM 2560 C CE  . LYS A 1 332 ? -3.064  40.477  0.829   1.0 50.10 ? 332 LYS A CE  1 Q8R3G1 UNP 332 K 
ATOM 2561 N NZ  . LYS A 1 332 ? -2.584  41.550  1.740   1.0 50.10 ? 332 LYS A NZ  1 Q8R3G1 UNP 332 K 
ATOM 2562 N N   . LYS A 1 333 ? -8.613  36.277  -0.886  1.0 59.56 ? 333 LYS A N   1 Q8R3G1 UNP 333 K 
ATOM 2563 C CA  . LYS A 1 333 ? -9.867  35.694  -0.379  1.0 59.56 ? 333 LYS A CA  1 Q8R3G1 UNP 333 K 
ATOM 2564 C C   . LYS A 1 333 ? -10.066 36.095  1.088   1.0 59.56 ? 333 LYS A C   1 Q8R3G1 UNP 333 K 
ATOM 2565 C CB  . LYS A 1 333 ? -9.878  34.163  -0.556  1.0 59.56 ? 333 LYS A CB  1 Q8R3G1 UNP 333 K 
ATOM 2566 O O   . LYS A 1 333 ? -9.220  35.826  1.938   1.0 59.56 ? 333 LYS A O   1 Q8R3G1 UNP 333 K 
ATOM 2567 C CG  . LYS A 1 333 ? -9.976  33.740  -2.033  1.0 59.56 ? 333 LYS A CG  1 Q8R3G1 UNP 333 K 
ATOM 2568 C CD  . LYS A 1 333 ? -10.024 32.210  -2.186  1.0 59.56 ? 333 LYS A CD  1 Q8R3G1 UNP 333 K 
ATOM 2569 C CE  . LYS A 1 333 ? -10.161 31.820  -3.666  1.0 59.56 ? 333 LYS A CE  1 Q8R3G1 UNP 333 K 
ATOM 2570 N NZ  . LYS A 1 333 ? -10.214 30.346  -3.857  1.0 59.56 ? 333 LYS A NZ  1 Q8R3G1 UNP 333 K 
ATOM 2571 N N   . LYS A 1 334 ? -11.184 36.766  1.357   1.0 60.55 ? 334 LYS A N   1 Q8R3G1 UNP 334 K 
ATOM 2572 C CA  . LYS A 1 334 ? -11.643 37.240  2.666   1.0 60.55 ? 334 LYS A CA  1 Q8R3G1 UNP 334 K 
ATOM 2573 C C   . LYS A 1 334 ? -12.561 36.155  3.243   1.0 60.55 ? 334 LYS A C   1 Q8R3G1 UNP 334 K 
ATOM 2574 C CB  . LYS A 1 334 ? -12.348 38.594  2.411   1.0 60.55 ? 334 LYS A CB  1 Q8R3G1 UNP 334 K 
ATOM 2575 O O   . LYS A 1 334 ? -13.635 35.936  2.697   1.0 60.55 ? 334 LYS A O   1 Q8R3G1 UNP 334 K 
ATOM 2576 C CG  . LYS A 1 334 ? -12.492 39.532  3.619   1.0 60.55 ? 334 LYS A CG  1 Q8R3G1 UNP 334 K 
ATOM 2577 C CD  . LYS A 1 334 ? -13.188 40.833  3.170   1.0 60.55 ? 334 LYS A CD  1 Q8R3G1 UNP 334 K 
ATOM 2578 C CE  . LYS A 1 334 ? -13.252 41.875  4.295   1.0 60.55 ? 334 LYS A CE  1 Q8R3G1 UNP 334 K 
ATOM 2579 N NZ  . LYS A 1 334 ? -14.022 43.080  3.887   1.0 60.55 ? 334 LYS A NZ  1 Q8R3G1 UNP 334 K 
ATOM 2580 N N   . TYR A 1 335 ? -12.129 35.445  4.285   1.0 50.85 ? 335 TYR A N   1 Q8R3G1 UNP 335 Y 
ATOM 2581 C CA  . TYR A 1 335 ? -12.983 34.477  4.984   1.0 50.85 ? 335 TYR A CA  1 Q8R3G1 UNP 335 Y 
ATOM 2582 C C   . TYR A 1 335 ? -13.959 35.208  5.912   1.0 50.85 ? 335 TYR A C   1 Q8R3G1 UNP 335 Y 
ATOM 2583 C CB  . TYR A 1 335 ? -12.142 33.437  5.739   1.0 50.85 ? 335 TYR A CB  1 Q8R3G1 UNP 335 Y 
ATOM 2584 O O   . TYR A 1 335 ? -13.564 36.120  6.643   1.0 50.85 ? 335 TYR A O   1 Q8R3G1 UNP 335 Y 
ATOM 2585 C CG  . TYR A 1 335 ? -11.622 32.320  4.852   1.0 50.85 ? 335 TYR A CG  1 Q8R3G1 UNP 335 Y 
ATOM 2586 C CD1 . TYR A 1 335 ? -12.438 31.199  4.596   1.0 50.85 ? 335 TYR A CD1 1 Q8R3G1 UNP 335 Y 
ATOM 2587 C CD2 . TYR A 1 335 ? -10.338 32.397  4.276   1.0 50.85 ? 335 TYR A CD2 1 Q8R3G1 UNP 335 Y 
ATOM 2588 C CE1 . TYR A 1 335 ? -11.976 30.161  3.765   1.0 50.85 ? 335 TYR A CE1 1 Q8R3G1 UNP 335 Y 
ATOM 2589 C CE2 . TYR A 1 335 ? -9.867  31.352  3.456   1.0 50.85 ? 335 TYR A CE2 1 Q8R3G1 UNP 335 Y 
ATOM 2590 O OH  . TYR A 1 335 ? -10.238 29.224  2.406   1.0 50.85 ? 335 TYR A OH  1 Q8R3G1 UNP 335 Y 
ATOM 2591 C CZ  . TYR A 1 335 ? -10.688 30.232  3.198   1.0 50.85 ? 335 TYR A CZ  1 Q8R3G1 UNP 335 Y 
ATOM 2592 N N   . ALA A 1 336 ? -15.231 34.811  5.860   1.0 60.25 ? 336 ALA A N   1 Q8R3G1 UNP 336 A 
ATOM 2593 C CA  . ALA A 1 336 ? -16.260 35.262  6.783   1.0 60.25 ? 336 ALA A CA  1 Q8R3G1 UNP 336 A 
ATOM 2594 C C   . ALA A 1 336 ? -15.982 34.684  8.177   1.0 60.25 ? 336 ALA A C   1 Q8R3G1 UNP 336 A 
ATOM 2595 C CB  . ALA A 1 336 ? -17.637 34.861  6.243   1.0 60.25 ? 336 ALA A CB  1 Q8R3G1 UNP 336 A 
ATOM 2596 O O   . ALA A 1 336 ? -15.787 33.485  8.354   1.0 60.25 ? 336 ALA A O   1 Q8R3G1 UNP 336 A 
ATOM 2597 N N   . LYS A 1 337 ? -15.919 35.578  9.160   1.0 55.43 ? 337 LYS A N   1 Q8R3G1 UNP 337 K 
ATOM 2598 C CA  . LYS A 1 337 ? -15.774 35.275  10.579  1.0 55.43 ? 337 LYS A CA  1 Q8R3G1 UNP 337 K 
ATOM 2599 C C   . LYS A 1 337 ? -17.179 35.036  11.129  1.0 55.43 ? 337 LYS A C   1 Q8R3G1 UNP 337 K 
ATOM 2600 C CB  . LYS A 1 337 ? -15.031 36.469  11.210  1.0 55.43 ? 337 LYS A CB  1 Q8R3G1 UNP 337 K 
ATOM 2601 O O   . LYS A 1 337 ? -17.841 35.994  11.514  1.0 55.43 ? 337 LYS A O   1 Q8R3G1 UNP 337 K 
ATOM 2602 C CG  . LYS A 1 337 ? -14.597 36.276  12.669  1.0 55.43 ? 337 LYS A CG  1 Q8R3G1 UNP 337 K 
ATOM 2603 C CD  . LYS A 1 337 ? -13.832 37.526  13.136  1.0 55.43 ? 337 LYS A CD  1 Q8R3G1 UNP 337 K 
ATOM 2604 C CE  . LYS A 1 337 ? -13.271 37.330  14.548  1.0 55.43 ? 337 LYS A CE  1 Q8R3G1 UNP 337 K 
ATOM 2605 N NZ  . LYS A 1 337 ? -12.492 38.513  14.998  1.0 55.43 ? 337 LYS A NZ  1 Q8R3G1 UNP 337 K 
ATOM 2606 N N   . GLU A 1 338 ? -17.648 33.792  11.115  1.0 56.83 ? 338 GLU A N   1 Q8R3G1 UNP 338 E 
ATOM 2607 C CA  . GLU A 1 338 ? -18.873 33.422  11.829  1.0 56.83 ? 338 GLU A CA  1 Q8R3G1 UNP 338 E 
ATOM 2608 C C   . GLU A 1 338 ? -18.590 33.357  13.332  1.0 56.83 ? 338 GLU A C   1 Q8R3G1 UNP 338 E 
ATOM 2609 C CB  . GLU A 1 338 ? -19.504 32.138  11.278  1.0 56.83 ? 338 GLU A CB  1 Q8R3G1 UNP 338 E 
ATOM 2610 O O   . GLU A 1 338 ? -17.662 32.699  13.809  1.0 56.83 ? 338 GLU A O   1 Q8R3G1 UNP 338 E 
ATOM 2611 C CG  . GLU A 1 338 ? -20.353 32.476  10.041  1.0 56.83 ? 338 GLU A CG  1 Q8R3G1 UNP 338 E 
ATOM 2612 C CD  . GLU A 1 338 ? -21.064 31.259  9.437   1.0 56.83 ? 338 GLU A CD  1 Q8R3G1 UNP 338 E 
ATOM 2613 O OE1 . GLU A 1 338 ? -22.034 31.500  8.687   1.0 56.83 ? 338 GLU A OE1 1 Q8R3G1 UNP 338 E 
ATOM 2614 O OE2 . GLU A 1 338 ? -20.599 30.128  9.692   1.0 56.83 ? 338 GLU A OE2 1 Q8R3G1 UNP 338 E 
ATOM 2615 N N   . ALA A 1 339 ? -19.358 34.159  14.063  1.0 55.21 ? 339 ALA A N   1 Q8R3G1 UNP 339 A 
ATOM 2616 C CA  . ALA A 1 339 ? -19.290 34.334  15.498  1.0 55.21 ? 339 ALA A CA  1 Q8R3G1 UNP 339 A 
ATOM 2617 C C   . ALA A 1 339 ? -20.159 33.276  16.186  1.0 55.21 ? 339 ALA A C   1 Q8R3G1 UNP 339 A 
ATOM 2618 C CB  . ALA A 1 339 ? -19.754 35.763  15.814  1.0 55.21 ? 339 ALA A CB  1 Q8R3G1 UNP 339 A 
ATOM 2619 O O   . ALA A 1 339 ? -21.358 33.191  15.935  1.0 55.21 ? 339 ALA A O   1 Q8R3G1 UNP 339 A 
ATOM 2620 N N   . TRP A 1 340 ? -19.554 32.504  17.085  1.0 47.63 ? 340 TRP A N   1 Q8R3G1 UNP 340 W 
ATOM 2621 C CA  . TRP A 1 340 ? -20.272 31.594  17.975  1.0 47.63 ? 340 TRP A CA  1 Q8R3G1 UNP 340 W 
ATOM 2622 C C   . TRP A 1 340 ? -21.026 32.378  19.064  1.0 47.63 ? 340 TRP A C   1 Q8R3G1 UNP 340 W 
ATOM 2623 C CB  . TRP A 1 340 ? -19.272 30.628  18.616  1.0 47.63 ? 340 TRP A CB  1 Q8R3G1 UNP 340 W 
ATOM 2624 O O   . TRP A 1 340 ? -20.409 33.216  19.731  1.0 47.63 ? 340 TRP A O   1 Q8R3G1 UNP 340 W 
ATOM 2625 C CG  . TRP A 1 340 ? -18.831 29.513  17.724  1.0 47.63 ? 340 TRP A CG  1 Q8R3G1 UNP 340 W 
ATOM 2626 C CD1 . TRP A 1 340 ? -17.813 29.540  16.834  1.0 47.63 ? 340 TRP A CD1 1 Q8R3G1 UNP 340 W 
ATOM 2627 C CD2 . TRP A 1 340 ? -19.450 28.199  17.588  1.0 47.63 ? 340 TRP A CD2 1 Q8R3G1 UNP 340 W 
ATOM 2628 C CE2 . TRP A 1 340 ? -18.731 27.463  16.601  1.0 47.63 ? 340 TRP A CE2 1 Q8R3G1 UNP 340 W 
ATOM 2629 C CE3 . TRP A 1 340 ? -20.562 27.568  18.187  1.0 47.63 ? 340 TRP A CE3 1 Q8R3G1 UNP 340 W 
ATOM 2630 N NE1 . TRP A 1 340 ? -17.747 28.328  16.173  1.0 47.63 ? 340 TRP A NE1 1 Q8R3G1 UNP 340 W 
ATOM 2631 C CH2 . TRP A 1 340 ? -20.198 25.557  16.846  1.0 47.63 ? 340 TRP A CH2 1 Q8R3G1 UNP 340 W 
ATOM 2632 C CZ2 . TRP A 1 340 ? -19.088 26.160  16.231  1.0 47.63 ? 340 TRP A CZ2 1 Q8R3G1 UNP 340 W 
ATOM 2633 C CZ3 . TRP A 1 340 ? -20.932 26.261  17.818  1.0 47.63 ? 340 TRP A CZ3 1 Q8R3G1 UNP 340 W 
ATOM 2634 N N   . PRO A 1 341 ? -22.319 32.105  19.308  1.0 59.57 ? 341 PRO A N   1 Q8R3G1 UNP 341 P 
ATOM 2635 C CA  . PRO A 1 341 ? -23.047 32.691  20.423  1.0 59.57 ? 341 PRO A CA  1 Q8R3G1 UNP 341 P 
ATOM 2636 C C   . PRO A 1 341 ? -22.882 31.850  21.702  1.0 59.57 ? 341 PRO A C   1 Q8R3G1 UNP 341 P 
ATOM 2637 C CB  . PRO A 1 341 ? -24.498 32.763  19.937  1.0 59.57 ? 341 PRO A CB  1 Q8R3G1 UNP 341 P 
ATOM 2638 O O   . PRO A 1 341 ? -23.018 30.632  21.687  1.0 59.57 ? 341 PRO A O   1 Q8R3G1 UNP 341 P 
ATOM 2639 C CG  . PRO A 1 341 ? -24.632 31.540  19.027  1.0 59.57 ? 341 PRO A CG  1 Q8R3G1 UNP 341 P 
ATOM 2640 C CD  . PRO A 1 341 ? -23.221 31.317  18.476  1.0 59.57 ? 341 PRO A CD  1 Q8R3G1 UNP 341 P 
ATOM 2641 N N   . GLY A 1 342 ? -22.671 32.523  22.838  1.0 49.33 ? 342 GLY A N   1 Q8R3G1 UNP 342 G 
ATOM 2642 C CA  . GLY A 1 342 ? -23.173 32.045  24.131  1.0 49.33 ? 342 GLY A CA  1 Q8R3G1 UNP 342 G 
ATOM 2643 C C   . GLY A 1 342 ? -22.192 31.350  25.083  1.0 49.33 ? 342 GLY A C   1 Q8R3G1 UNP 342 G 
ATOM 2644 O O   . GLY A 1 342 ? -22.287 30.150  25.317  1.0 49.33 ? 342 GLY A O   1 Q8R3G1 UNP 342 G 
ATOM 2645 N N   . LYS A 1 343 ? -21.368 32.130  25.796  1.0 53.01 ? 343 LYS A N   1 Q8R3G1 UNP 343 K 
ATOM 2646 C CA  . LYS A 1 343 ? -21.029 31.818  27.197  1.0 53.01 ? 343 LYS A CA  1 Q8R3G1 UNP 343 K 
ATOM 2647 C C   . LYS A 1 343 ? -21.718 32.834  28.107  1.0 53.01 ? 343 LYS A C   1 Q8R3G1 UNP 343 K 
ATOM 2648 C CB  . LYS A 1 343 ? -19.509 31.771  27.445  1.0 53.01 ? 343 LYS A CB  1 Q8R3G1 UNP 343 K 
ATOM 2649 O O   . LYS A 1 343 ? -21.364 34.009  28.092  1.0 53.01 ? 343 LYS A O   1 Q8R3G1 UNP 343 K 
ATOM 2650 C CG  . LYS A 1 343 ? -18.864 30.462  26.953  1.0 53.01 ? 343 LYS A CG  1 Q8R3G1 UNP 343 K 
ATOM 2651 C CD  . LYS A 1 343 ? -17.685 30.052  27.852  1.0 53.01 ? 343 LYS A CD  1 Q8R3G1 UNP 343 K 
ATOM 2652 C CE  . LYS A 1 343 ? -17.086 28.722  27.379  1.0 53.01 ? 343 LYS A CE  1 Q8R3G1 UNP 343 K 
ATOM 2653 N NZ  . LYS A 1 343 ? -16.146 28.152  28.378  1.0 53.01 ? 343 LYS A NZ  1 Q8R3G1 UNP 343 K 
ATOM 2654 N N   . LYS A 1 344 ? -22.702 32.382  28.892  1.0 61.28 ? 344 LYS A N   1 Q8R3G1 UNP 344 K 
ATOM 2655 C CA  . LYS A 1 344 ? -23.237 33.145  30.030  1.0 61.28 ? 344 LYS A CA  1 Q8R3G1 UNP 344 K 
ATOM 2656 C C   . LYS A 1 344 ? -22.276 33.004  31.222  1.0 61.28 ? 344 LYS A C   1 Q8R3G1 UNP 344 K 
ATOM 2657 C CB  . LYS A 1 344 ? -24.647 32.668  30.422  1.0 61.28 ? 344 LYS A CB  1 Q8R3G1 UNP 344 K 
ATOM 2658 O O   . LYS A 1 344 ? -21.834 31.885  31.484  1.0 61.28 ? 344 LYS A O   1 Q8R3G1 UNP 344 K 
ATOM 2659 C CG  . LYS A 1 344 ? -25.718 33.019  29.375  1.0 61.28 ? 344 LYS A CG  1 Q8R3G1 UNP 344 K 
ATOM 2660 C CD  . LYS A 1 344 ? -27.127 32.696  29.900  1.0 61.28 ? 344 LYS A CD  1 Q8R3G1 UNP 344 K 
ATOM 2661 C CE  . LYS A 1 344 ? -28.197 33.074  28.865  1.0 61.28 ? 344 LYS A CE  1 Q8R3G1 UNP 344 K 
ATOM 2662 N NZ  . LYS A 1 344 ? -29.572 32.772  29.346  1.0 61.28 ? 344 LYS A NZ  1 Q8R3G1 UNP 344 K 
ATOM 2663 N N   . PRO A 1 345 ? -21.950 34.090  31.939  1.0 55.41 ? 345 PRO A N   1 Q8R3G1 UNP 345 P 
ATOM 2664 C CA  . PRO A 1 345 ? -21.158 34.026  33.160  1.0 55.41 ? 345 PRO A CA  1 Q8R3G1 UNP 345 P 
ATOM 2665 C C   . PRO A 1 345 ? -22.049 33.655  34.356  1.0 55.41 ? 345 PRO A C   1 Q8R3G1 UNP 345 P 
ATOM 2666 C CB  . PRO A 1 345 ? -20.533 35.418  33.287  1.0 55.41 ? 345 PRO A CB  1 Q8R3G1 UNP 345 P 
ATOM 2667 O O   . PRO A 1 345 ? -23.098 34.256  34.575  1.0 55.41 ? 345 PRO A O   1 Q8R3G1 UNP 345 P 
ATOM 2668 C CG  . PRO A 1 345 ? -21.585 36.339  32.667  1.0 55.41 ? 345 PRO A CG  1 Q8R3G1 UNP 345 P 
ATOM 2669 C CD  . PRO A 1 345 ? -22.264 35.472  31.607  1.0 55.41 ? 345 PRO A CD  1 Q8R3G1 UNP 345 P 
ATOM 2670 N N   . THR A 1 346 ? -21.629 32.662  35.135  1.0 62.00 ? 346 THR A N   1 Q8R3G1 UNP 346 T 
ATOM 2671 C CA  . THR A 1 346 ? -22.174 32.349  36.464  1.0 62.00 ? 346 THR A CA  1 Q8R3G1 UNP 346 T 
ATOM 2672 C C   . THR A 1 346 ? -21.588 33.305  37.508  1.0 62.00 ? 346 THR A C   1 Q8R3G1 UNP 346 T 
ATOM 2673 C CB  . THR A 1 346 ? -21.784 30.916  36.876  1.0 62.00 ? 346 THR A CB  1 Q8R3G1 UNP 346 T 
ATOM 2674 O O   . THR A 1 346 ? -20.361 33.352  37.623  1.0 62.00 ? 346 THR A O   1 Q8R3G1 UNP 346 T 
ATOM 2675 C CG2 . THR A 1 346 ? -22.641 29.860  36.184  1.0 62.00 ? 346 THR A CG2 1 Q8R3G1 UNP 346 T 
ATOM 2676 O OG1 . THR A 1 346 ? -20.435 30.667  36.527  1.0 62.00 ? 346 THR A OG1 1 Q8R3G1 UNP 346 T 
ATOM 2677 N N   . PRO A 1 347 ? -22.394 34.026  38.307  1.0 61.19 ? 347 PRO A N   1 Q8R3G1 UNP 347 P 
ATOM 2678 C CA  . PRO A 1 347 ? -21.910 34.651  39.530  1.0 61.19 ? 347 PRO A CA  1 Q8R3G1 UNP 347 P 
ATOM 2679 C C   . PRO A 1 347 ? -21.884 33.619  40.669  1.0 61.19 ? 347 PRO A C   1 Q8R3G1 UNP 347 P 
ATOM 2680 C CB  . PRO A 1 347 ? -22.862 35.818  39.788  1.0 61.19 ? 347 PRO A CB  1 Q8R3G1 UNP 347 P 
ATOM 2681 O O   . PRO A 1 347 ? -22.900 33.013  41.006  1.0 61.19 ? 347 PRO A O   1 Q8R3G1 UNP 347 P 
ATOM 2682 C CG  . PRO A 1 347 ? -24.189 35.332  39.203  1.0 61.19 ? 347 PRO A CG  1 Q8R3G1 UNP 347 P 
ATOM 2683 C CD  . PRO A 1 347 ? -23.790 34.372  38.076  1.0 61.19 ? 347 PRO A CD  1 Q8R3G1 UNP 347 P 
ATOM 2684 N N   . SER A 1 348 ? -20.705 33.413  41.250  1.0 61.89 ? 348 SER A N   1 Q8R3G1 UNP 348 S 
ATOM 2685 C CA  . SER A 1 348 ? -20.505 32.678  42.499  1.0 61.89 ? 348 SER A CA  1 Q8R3G1 UNP 348 S 
ATOM 2686 C C   . SER A 1 348 ? -21.100 33.463  43.668  1.0 61.89 ? 348 SER A C   1 Q8R3G1 UNP 348 S 
ATOM 2687 C CB  . SER A 1 348 ? -19.004 32.454  42.720  1.0 61.89 ? 348 SER A CB  1 Q8R3G1 UNP 348 S 
ATOM 2688 O O   . SER A 1 348 ? -20.690 34.595  43.929  1.0 61.89 ? 348 SER A O   1 Q8R3G1 UNP 348 S 
ATOM 2689 O OG  . SER A 1 348 ? -18.300 33.666  42.508  1.0 61.89 ? 348 SER A OG  1 Q8R3G1 UNP 348 S 
ATOM 2690 N N   . LEU A 1 349 ? -22.055 32.842  44.360  1.0 60.44 ? 349 LEU A N   1 Q8R3G1 UNP 349 L 
ATOM 2691 C CA  . LEU A 1 349 ? -22.589 33.285  45.642  1.0 60.44 ? 349 LEU A CA  1 Q8R3G1 UNP 349 L 
ATOM 2692 C C   . LEU A 1 349 ? -21.517 33.095  46.727  1.0 60.44 ? 349 LEU A C   1 Q8R3G1 UNP 349 L 
ATOM 2693 C CB  . LEU A 1 349 ? -23.859 32.460  45.960  1.0 60.44 ? 349 LEU A CB  1 Q8R3G1 UNP 349 L 
ATOM 2694 O O   . LEU A 1 349 ? -20.903 32.031  46.811  1.0 60.44 ? 349 LEU A O   1 Q8R3G1 UNP 349 L 
ATOM 2695 C CG  . LEU A 1 349 ? -25.031 33.292  46.519  1.0 60.44 ? 349 LEU A CG  1 Q8R3G1 UNP 349 L 
ATOM 2696 C CD1 . LEU A 1 349 ? -26.139 33.422  45.468  1.0 60.44 ? 349 LEU A CD1 1 Q8R3G1 UNP 349 L 
ATOM 2697 C CD2 . LEU A 1 349 ? -25.629 32.641  47.764  1.0 60.44 ? 349 LEU A CD2 1 Q8R3G1 UNP 349 L 
ATOM 2698 N N   . LEU A 1 350 ? -21.308 34.124  47.541  1.0 50.27 ? 350 LEU A N   1 Q8R3G1 UNP 350 L 
ATOM 2699 C CA  . LEU A 1 350 ? -20.476 34.117  48.739  1.0 50.27 ? 350 LEU A CA  1 Q8R3G1 UNP 350 L 
ATOM 2700 C C   . LEU A 1 350 ? -21.341 34.741  49.841  1.0 50.27 ? 350 LEU A C   1 Q8R3G1 UNP 350 L 
ATOM 2701 C CB  . LEU A 1 350 ? -19.165 34.879  48.419  1.0 50.27 ? 350 LEU A CB  1 Q8R3G1 UNP 350 L 
ATOM 2702 O O   . LEU A 1 350 ? -21.560 35.948  49.800  1.0 50.27 ? 350 LEU A O   1 Q8R3G1 UNP 350 L 
ATOM 2703 C CG  . LEU A 1 350 ? -17.948 34.540  49.304  1.0 50.27 ? 350 LEU A CG  1 Q8R3G1 UNP 350 L 
ATOM 2704 C CD1 . LEU A 1 350 ? -16.660 34.740  48.497  1.0 50.27 ? 350 LEU A CD1 1 Q8R3G1 UNP 350 L 
ATOM 2705 C CD2 . LEU A 1 350 ? -17.849 35.417  50.553  1.0 50.27 ? 350 LEU A CD2 1 Q8R3G1 UNP 350 L 
ATOM 2706 N N   . ILE A 1 351 ? -21.910 33.890  50.701  1.0 52.42 ? 351 ILE A N   1 Q8R3G1 UNP 351 I 
ATOM 2707 C CA  . ILE A 1 351 ? -22.368 34.064  52.097  1.0 52.42 ? 351 ILE A CA  1 Q8R3G1 UNP 351 I 
ATOM 2708 C C   . ILE A 1 351 ? -22.678 32.663  52.623  1.0 52.42 ? 351 ILE A C   1 Q8R3G1 UNP 351 I 
ATOM 2709 C CB  . ILE A 1 351 ? -23.569 35.029  52.254  1.0 52.42 ? 351 ILE A CB  1 Q8R3G1 UNP 351 I 
ATOM 2710 O O   . ILE A 1 351 ? -23.325 31.895  51.871  1.0 52.42 ? 351 ILE A O   1 Q8R3G1 UNP 351 I 
ATOM 2711 C CG1 . ILE A 1 351 ? -23.077 36.484  52.450  1.0 52.42 ? 351 ILE A CG1 1 Q8R3G1 UNP 351 I 
ATOM 2712 C CG2 . ILE A 1 351 ? -24.435 34.697  53.488  1.0 52.42 ? 351 ILE A CG2 1 Q8R3G1 UNP 351 I 
ATOM 2713 C CD1 . ILE A 1 351 ? -24.064 37.516  51.895  1.0 52.42 ? 351 ILE A CD1 1 Q8R3G1 UNP 351 I 
ATOM 2714 O OXT . ILE A 1 351 ? -22.184 32.395  53.737  1.0 52.42 ? 351 ILE A OXT 1 Q8R3G1 UNP 351 I 
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