The data we collected and organised, accessible for your research.
Database with information on the early/intermediate/late folding regions of proteins, and their unfolding, from hydrogen/deuterium exchange data from NMR and X-ray crystallography
Developers: Rita Pancsa, Mihaly Varadi,
Funding: G.0328.16N (FWO),
Noumenon is a bias-free dataset for the validation of contact prediction methods.
Developers: Daniele Raimondi,
Funding: BB2B 2010-1-12 (Innoviris), Ph.D. grant Daniele Raimondi (IWT),
This website provides sequence-based predictions for all proteins that compose the SARS-CoV-2 virus. Its aim is to provide information on the possible behaviour of these proteins that is not evident from structure nor sequence directly.
Developers: Luciano Kagami, Wim Vranken,
Funding: G.0328.16N (FWO),
Sequence-based predictions for the characteristics of the proteins that compose the human proteome.
Developers: Adrian Diaz, Wim Vranken,
Funding: FWOESFRI2 (ELIXIR-Belgium),
Interactive database of AlphaFold models aligned to dynamics information from experimental NMR parameters and computational metrics: This resource enables exploration of datasets where AlphaFold models were correlated with (interpreted) NMR or MD data for proteins in solution, as described in our original large scale analysis. The AlphaFold pLDDT is, for each protein, mapped to the information for three different datasets, with the results visualised at the sequence and structure level.
Developers: Adrian Diaz, Bhawna Dixit, Jose Gavaldá-GarcĂa,
Funding: No funding associated.
GPCRchimeraDB is the only database to describe chimeric GPCRs and their parents at such an extend: 1. Centralize previously designed chimeric GPCRs available in the literature in a single location. 2. Describe both chimeric and natural at the sequence, structural and biophysical level. 3. Support the design of novel chimeric GPCRs to make more GPCR druggable.
Developers: Charlotte Crauwels, Adrian Diaz,
Funding: G.0328.16N (FWO),
AmyPro is a database with information on aggregating regions of proteins.
DisProt is a database with annotations on disordered regions of proteins based on experimental observations.
MobiDB is a database of (predicted) annotations on protein disorder and mobility
The PBDe-KB (Knowledge base) is an extensive collection of annotations for protein structures at the EBI> It includes our DynaMine and EFoldMine predictions.
Web server that provides quick predictions for the effect of mutations on proteins and visualization tools for a comprehensive view of mutational landscape