The Bio2Byte group is led by Prof. Dr. Wim Vranken, with many people contributing to the research


If you are interested in our work, keep an eye on the publications in which the lab has been involved.


For joining us, have a look at what possible opportunities we have.


The Bio2Byte group is primarily situated at the Interuniversity Institute of Bioinformatics in Brussels, a collaborative interfaculty institute between the Vrije Universiteit Brussel and the Université Libre de Bruxelles. It is located at the the ULB side of the Pleinlaan/La Plaine campus on the 6th floor of the C building.

At the VUB, the group is linked to Structural Biology Brussels at the Bioengineering sciences department, as well as the departments of Computer Science and Chemistry at the Faculty of Sciences, plus to the Biomedical sciences at the Faculty of Medicine and Pharmacy.


Our research is funded from various sources, listed below:
  • FWO-IRI ELIXIR (Jan. 1, 2023-Dec. 31, 2026) from FWO

    Infrastructure grant from the Flemish government for ELIXIR-Belgium, where we receive funding to develop services for the 2023-2026 period.

  • O&O project with Confo therapeutics (Jan. 1, 2023-Dec. 31, 2024) from VLAIO

    We receive funding from this O&O project to connect our tools to inside approaches at Confo Therapeutics to help with the in silico screening of new target proteins.

  • FWO-SB (Nov. 1, 2022-Oct. 31, 2026) from FWO

    FWO-SB grant to Charlotte Crauwels to work on the design of hybrid GPCRs

  • Synthetic biology SRP (Oct. 1, 2022-Sept. 30, 2027) from VUB

    Strategic Research Project (SRP) from the VUB with as topic 'Synthetic biology for the development of microbial cell factories'. Other partners are Eveline Peeters and Sophie de Buyl, both VUB.

  • PhD grant (May 1, 2022-April 30, 2026) from FNRS

    Grant for Sophie-Luise Heidig from the FNRS in a joint PhD with the ULB (Francois Flot).

  • Hosmart-AI (April 1, 2021-March 31, 2025) from EC

    Hosmart-AI is a European project to develop a marketplace for AI solutions in the health sector. We contribute one of the 'pilots' in this grant, based on TumorScope.

  • ProteinContour (Jan. 1, 2021-Dec. 12, 2024) from FWO

    In this project (FWO identifier G028821N), we combine mass spectrometry analysis expertise from UGent (CompOmics group, Lennart Martens) and UCL (Laurent Gatto) with our predictions to map the relationships between post-translational modifications, sub cellular location, interactions and biophysical features of proteins in human cells.

  • Implementation studies (Jan. 1, 2021-May 31, 2023) from ELIXIR

    We participated in several ELIXIR implementation studies (IDP, IDPTools), with focus on creating connections between the IDP and other ELIXIR communities (3DBioinfo, proteomics).

  • TumorScope (Oct. 1, 2019-Sept. 30, 2024) from VUB

    In this interdisciplinary research project (IRP) from the VUB, we leverage the unique expertise and data present at the VUB and the UZ Brussel to create a general framework to store and analyze raw medical data, both at the image and molecular level, in relation to solid tumors, their clinical behavior and response to therapies. An integrated research platform, which conforms to GDPR and patient legislation, will enable AI-driven extraction of new information on breast and brain tumors, as well as sarcomas. Combined with expert insights from clinicians, we will work towards assisting and improving the decision-making process in especially multi-disciplinary oncology consults (MOC).

  • RNAct (Jan. 1, 2019-Dec. 31, 2023) from EC

    The H2020-MSCA-ITN-2018 813239 RNAct project focusses on 'Enabling proteins with RNA recognition motifs for synthetic biology and bio-analytics'.

  • FWOESFRI2 (Nov. 6, 2017-Dec. 31, 2019) from ELIXIR-Belgium

    Bringing European standards to Brussels : Preparing the human health related (IB)2 services and databases for ELIXIR.

  • G.0328.16N (Jan. 1, 2016-Dec. 31, 2019) from FWO

    FoldMod - The role of local amino acid interactions in the folding of proteins, the stability of their fold and the location of post-translational modifications.

  • ICITY-RDI.BRU (Jan. 1, 2014-Dec. 31, 2023) from ICITY

    A software framework for identifying molecular causes of human diseases (Mutaframe)

  • Ph.D. grant Daniele Raimondi (Jan. 1, 2013-Dec. 31, 2017) from IWT

    Advancing the prediction and understanding of coding variant effects

  • BB2B 2010-1-12 (Dec. 1, 2010-Nov. 30, 2015) from Innoviris

    Brains Back to Brussels project - Combining experiment and informatics to study biopolymer dynamics and interactions.