The Bio2Byte group is led by Prof. Dr. Wim Vranken, with many people contributing to the research.
About our research group.
The Bio2Byte group is led by Prof. Dr. Wim Vranken, with many people contributing to the research.
If you are interested in our work, keep an eye on the publications in which the lab has been involved.
For any further questions, feedback or suggestions, please send an email to: bio2byte@vub.be.
Stay updated with our latest news, projects, and collaborations by following us on our social media and platforms:
For joining us, have a look at what possible opportunities we have.
The Bio2Byte group is primarily situated at the Interuniversity Institute of Bioinformatics in Brussels, a collaborative interfaculty institute between the Vrije Universiteit Brussel and the Université Libre de Bruxelles. It is located at the the ULB side of the Pleinlaan/La Plaine campus on the 6th floor of the C building.
At the VUB, the group is linked to Structural Biology Brussels at the Bioengineering sciences department, as well as the departments of Computer Science and Chemistry at the Faculty of Sciences, plus to the Biomedical sciences at the Faculty of Medicine and Pharmacy.
Our research is funded from various sources, listed below:
PROHITS is a MSCA doctoral network (DN) action coordinated by us. The overall aim of PROHITS is to integrate experimental and computational approaches that can resolve the proteome of prokaryotes at single cell level, and at a range of temperatures, in order to improve our understanding of thermophile biology and to guide the optimized design of cell factories. For more information, please go to https://prohits.eu.
Infrastructure grant from the Flemish government for ELIXIR-Belgium, where we receive funding to develop services for the 2023-2026 period.
We receive funding from this O&O project to connect our tools to inside approaches at Confo Therapeutics to help with the in silico screening of new target proteins.
FWO-SB grant to Charlotte Crauwels to work on the design of hybrid GPCRs
Strategic Research Project (SRP) from the VUB with as topic 'Synthetic biology for the development of microbial cell factories'. Other partners are Eveline Peeters and Sophie de Buyl, both VUB.
Grant for Sophie-Luise Heidig from the FNRS in a joint PhD with the ULB (Francois Flot).
Hosmart-AI is a European project to develop a marketplace for AI solutions in the health sector. We contribute one of the 'pilots' in this grant, based on TumorScope.
In this project (FWO identifier G028821N), we combine mass spectrometry analysis expertise from UGent (CompOmics group, Lennart Martens) and UCL (Laurent Gatto) with our predictions to map the relationships between post-translational modifications, sub cellular location, interactions and biophysical features of proteins in human cells.
We participated in several ELIXIR implementation studies (IDP, IDPTools), with focus on creating connections between the IDP and other ELIXIR communities (3DBioinfo, proteomics).
In this interdisciplinary research project (IRP) from the VUB, we leverage the unique expertise and data present at the VUB and the UZ Brussel to create a general framework to store and analyze raw medical data, both at the image and molecular level, in relation to solid tumors, their clinical behavior and response to therapies. An integrated research platform, which conforms to GDPR and patient legislation, will enable AI-driven extraction of new information on breast and brain tumors, as well as sarcomas. Combined with expert insights from clinicians, we will work towards assisting and improving the decision-making process in especially multi-disciplinary oncology consults (MOC).
The H2020-MSCA-ITN-2018 813239 RNAct project focusses on 'Enabling proteins with RNA recognition motifs for synthetic biology and bio-analytics'.
Bringing European standards to Brussels : Preparing the human health related (IB)2 services and databases for ELIXIR.
FoldMod - The role of local amino acid interactions in the folding of proteins, the stability of their fold and the location of post-translational modifications.
A software framework for identifying molecular causes of human diseases (Mutaframe)
Advancing the prediction and understanding of coding variant effects
Brains Back to Brussels project - Combining experiment and informatics to study biopolymer dynamics and interactions.