Traditionally, proteins are described in a single static state (a picture). It is now increasingly recognised that many proteins can adopt multiple states and move between these conformational states dynamically (a movie). Even more, not every protein has a well-defined three-dimensional structure, many are partly or fully disordered. These predictions describe backbone and side-chain dynamics, disorder, early folding events, beta-sheet aggregation and phase separation.
In this atlas
Entries here
Genes
Chromosomes
Reviewed in UniProt
Last updated 4 seconds ago.
About this proteome
Extracted from UniProtKB
The house mouse (Mus musculus) is a common rodent that is distributed throughout the world. It has become a frequently used model for understanding human disease and development due to its small size, short life-cycle and rapid breeding cycle. The mouse was the second mammal to have its genome sequenced. The mouse strain used for sequencing was C57BL/6J, which is the most widely used inbred strain. This strain is a permissive background for the expression of most mutations, but is resilient to many tumors. C57BL/6J mice are susceptible to atherosclerosis, type 2 diabetes and diet-induced obesity. It also develops age-related hearing loss. 75% of the mouse genes are in 1:1 orthologous relationships to human genes and have most likely maintained their ancestral function in both species. The reference proteome of Mus musculus is derived from the genome sequence of strain C57BL/6J that was published in 2009. The size of the genome is 2.6 Gb.
What is included
This atlas covers the reviewed entries of this proteome — the manually curated Swiss-Prot section of UniProtKB. That is 31.5% of it. The other 37,578 entries are unreviewed (TrEMBL) and are not included, which is why the count above is smaller than the proteome. You can run the same predictions on any of them yourself in the online predictors.
- UniProt proteome
- UP000000589
- Taxonomy
- 10090 · MOUSE
- Proteome type
- Reference proteome
- Strain
- C57BL/6J
- Superkingdom
- eukaryota
- Genome assembly
- GCA_000001635.9 · Ensembl
- Completeness (BUSCO)
- 99% · 13767/13798
Source: UniProt proteome UP000000589, last modified 22 Apr 2026. Retrieved 11 Sep 2026 (6 hours ago) and cached for a week.
Most viewed mouse proteins
What visitors are reading in this proteome — 2,952 entry views in total.
- 1 B2RVY9 · Tmem182 Chromosome 1 10 views
- 2 A7MCT6 · Etnk2 Chromosome 1 9 views
- 3 A9Q751 · Cfap221 Chromosome 1 9 views
- 4 Q3V1G4 · Olfml2b Chromosome 1 9 views
- 5 B2RPY5 · Gpr161 Chromosome 1 7 views
- 6 E9PUQ8 · Dgkd Chromosome 1 7 views
- 7 Q3UU96 · Cdc42bpa Chromosome 1 7 views
- 8 Q3V089 · Rbm44 Chromosome 1 7 views
- 9 Q61137 · Astn1 Chromosome 1 7 views
- 10 Q69ZM6 · Stk36 Chromosome 1 7 views
What do we provide?
Sequence-based predictions that help explain the behaviour of the proteins in the mouse proteome. Not all of these proteins, or regions of them, have a well-defined three-dimensional structure as available from the PDB; many are dynamic or ambiguous. These predictions give clues as to how such regions behave.
- DynaMine
- backbone and side-chain dynamics
- DisoMine
- disorder
- EFoldMine
- early folding
- AgMata
- beta-sheet aggregation
- PSPer
- phase separation
How do I proceed?
Open the entry list and click a UniProt accession. Each entry page carries:
- Overview — every prediction on one plot.
- Interpretation — disorder classified as order, transition or disorder.
- Values and Statistics — the numbers behind the plots.
- Sequence — residues coloured by prediction.
- PSP — phase-separation propensity.
- Visualization 1D-3D — a 3D model coloured by prediction.
- Downloads — sequence, predictions and structures.
Prefer code? Everything is available through the REST API.