Traditionally, proteins are described in a single static state (a picture). It is now increasingly recognised that many proteins can adopt multiple states and move between these conformational states dynamically (a movie). Even more, not every protein has a well-defined three-dimensional structure, many are partly or fully disordered. These predictions describe backbone and side-chain dynamics, disorder, early folding events, beta-sheet aggregation and phase separation.
In this atlas
Entries here
Genes
Chromosomes
Reviewed in UniProt
Last updated 2 days, 10 hours ago.
About this proteome
Extracted from UniProtKB
Rattus norvegicus (also called the brown rat, Hanover rat, Norwegian rat, Brown Norway rat) is a common rodent closely related to mouse. The species originated in Asia, not Norway as the name suggests, and has spread throughout the world. The rat is a major pest and a reservoir of pathogens, being involved in the transmission of infectious diseases such as cholera, bubonic plague and typhus. On the other hand, Rattus norvegicus was the first mammalian species to be domesticated for scientific research. The rat is an indispensable model organism in biomedical research, especially in cardiovascular and psychological research, and in therapeutic efficacy and toxicity studies. It is the third mammalian species to have its genome sequenced. The reference proteome of Rattus norvegicus is derived from the genome sequence of strain Brown Norway (BN) that was published in 2004. The sequence data were mostly from two inbred female animals of strain BN/SsNHsd/Mcwi. The assembled genome size is 2.75 Gb.
What is included
This atlas covers the reviewed entries of this proteome — the manually curated Swiss-Prot section of UniProtKB. That is 15.6% of it. The other 44,600 entries are unreviewed (TrEMBL) and are not included, which is why the count above is smaller than the proteome. You can run the same predictions on any of them yourself in the online predictors.
- UniProt proteome
- UP000002494
- Taxonomy
- 10116 · RAT
- Proteome type
- Reference proteome
- Strain
- Brown Norway
- Superkingdom
- eukaryota
- Genome assembly
- GCA_036323735.1 · Ensembl
- Completeness (BUSCO)
- 96% · 13236/13798
Source: UniProt proteome UP000002494, last modified 5 Dec 2025. Retrieved 19 Aug 2026 (2 days, 6 hours ago) and cached for a week.
What do we provide?
Sequence-based predictions that help explain the behaviour of the proteins in the rat proteome. Not all of these proteins, or regions of them, have a well-defined three-dimensional structure as available from the PDB; many are dynamic or ambiguous. These predictions give clues as to how such regions behave.
- DynaMine
- backbone and side-chain dynamics
- DisoMine
- disorder
- EFoldMine
- early folding
- AgMata
- beta-sheet aggregation
- PSPer
- phase separation
How do I proceed?
Open the entry list and click a UniProt accession. Each entry page carries:
- Overview — every prediction on one plot.
- Interpretation — disorder classified as order, transition or disorder.
- Values and Statistics — the numbers behind the plots.
- Sequence — residues coloured by prediction.
- PSP — phase-separation propensity.
- Visualization 1D-3D — a 3D model coloured by prediction.
- Downloads — sequence, predictions and structures.
Prefer code? Everything is available through the REST API.