Biophysical Proteome Atlas

Thermus thermophilus HB8

Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

Sequence-based biophysical predictions for the thermus thermophilus hb8 reference proteome from UniProt.

Traditionally, proteins are described in a single static state (a picture). It is now increasingly recognised that many proteins can adopt multiple states and move between these conformational states dynamically (a movie). Even more, not every protein has a well-defined three-dimensional structure, many are partly or fully disordered. These predictions describe backbone and side-chain dynamics, disorder, early folding events, beta-sheet aggregation and phase separation.


In this atlas

439

Entries here

439

Genes

2

Chromosomes

441

Reviewed in UniProt

Browse all entries

Last updated 1 week, 6 days ago.

About this proteome

Extracted from UniProtKB

Thermus thermophilus is an extremely thermophilic, halotolerant bacterium. It was isolated from a natural thermal environment in Japan. It has an optimal growth temperature of about 85 degrees Celsius. T.thermophilus has become a model organism in structural biology and some of its enzymes have a biotechnological application.

What is included

This atlas covers the reviewed entries of this proteome — the manually curated Swiss-Prot section of UniProtKB. That is 19.8% of it. The other 1,786 entries are unreviewed (TrEMBL) and are not included, which is why the count above is smaller than the proteome. You can run the same predictions on any of them yourself in the online predictors.

441 reviewed · 19.8% 1,786 unreviewed · 80.2% 2,227 in the proteome
UniProt proteome
UP000000532
Taxonomy
300852 · THET8
Proteome type
Reference proteome
Strain
ATCC 27634 / DSM 579 / HB8
Superkingdom
bacteria
Genome assembly
GCA_000091545.1 · ENA/EMBL
Completeness (BUSCO)
91% · 109/124

Source: UniProt proteome UP000000532, last modified 5 Apr 2026. Retrieved 11 Sep 2026 (7 hours ago) and cached for a week.


Most viewed thermus thermophilus hb8 proteins

What visitors are reading in this proteome — 1,750 entry views in total.

  1. 1 O50606 · mutM FPG_THET8 Chromosome Chromosome 12 views
  2. 2 P21777 · pfkA PFKA1_THET8 Chromosome Chromosome 11 views
  3. 3 Q5SLN1 · pstB PSTB_THET8 Chromosome Chromosome 11 views
  4. 4 Q5SHH5 · lysJ LYSJ_THET8 Chromosome Chromosome 10 views
  5. 5 Q5SJ39 · rimO RIMO_THET8 Chromosome Chromosome 10 views
  6. 6 Q5SJ47 · recJ RECJ_THET8 Chromosome Chromosome 10 views
  7. 7 P80373 · rpsD RS4_THET8 Chromosome Chromosome 9 views
  8. 8 P05378 · trpE TRPE_THET8 Chromosome Chromosome 8 views
  9. 9 Q5SHT5 · mutS2 MUTS2_THET8 Chromosome Chromosome 8 views
  10. 10 Q5SLR4 · TTHA0229 ODBA_THET8 Chromosome Chromosome 8 views

What do we provide?

Sequence-based predictions that help explain the behaviour of the proteins in the thermus thermophilus hb8 proteome. Not all of these proteins, or regions of them, have a well-defined three-dimensional structure as available from the PDB; many are dynamic or ambiguous. These predictions give clues as to how such regions behave.

DynaMine
backbone and side-chain dynamics
DisoMine
disorder
EFoldMine
early folding
AgMata
beta-sheet aggregation
PSPer
phase separation

How do I proceed?

Open the entry list and click a UniProt accession. Each entry page carries:

  • Overview — every prediction on one plot.
  • Interpretation — disorder classified as order, transition or disorder.
  • Values and Statistics — the numbers behind the plots.
  • Sequence — residues coloured by prediction.
  • PSP — phase-separation propensity.
  • Visualization 1D-3D — a 3D model coloured by prediction.
  • Downloads — sequence, predictions and structures.

Prefer code? Everything is available through the REST API.